{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T10:25:05Z","timestamp":1785493505385,"version":"3.56.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30 CA016672"],"award-info":[{"award-number":["P30 CA016672"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int J Emerg Med"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12245-017-0144-9","type":"journal-article","created":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T12:41:01Z","timestamp":1496752861000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Discharge or admit? Emergency department management of incidental pulmonary embolism in patients with cancer: a retrospective study"],"prefix":"10.1186","volume":"10","author":[{"given":"Srinivas R.","family":"Banala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai-Ching Jim","family":"Yeung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry W.","family":"Rice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cielito C.","family":"Reyes-Gibby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol C.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knox H.","family":"Todd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Frank","family":"Peacock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumar","family":"Alagappan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"issue":"3","key":"144_CR1","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1111\/acem.12615","volume":"22","author":"GJ Fermann","year":"2015","unstructured":"Fermann GJ, Erkens PM, Prins MH, Wells PS, Pap AF, Lensing AW. Treatment of pulmonary embolism with rivaroxaban: outcomes by simplified pulmonary embolism severity index score from a post hoc analysis of the EINSTEIN PE study. Acad Emerg Med. 2015;22(3):299\u2013307.","journal-title":"Acad Emerg Med"},{"issue":"18","key":"144_CR2","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.1093\/eurheartj\/ehn310","volume":"29","author":"A Torbicki","year":"2008","unstructured":"Torbicki A, Perrier A, Konstantinides S, Agnelli G, Galie N, Pruszczyk P, et al. Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J. 2008;29(18):2276\u2013315.","journal-title":"Eur Heart J"},{"issue":"3","key":"144_CR3","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1067\/mem.2001.113703","volume":"37","author":"DR Vinson","year":"2001","unstructured":"Vinson DR, Berman DA. Outpatient treatment of deep venous thrombosis: a clinical care pathway managed by the emergency department. Ann Emerg Med. 2001;37(3):251\u20138.","journal-title":"Ann Emerg Med"},{"issue":"2 Suppl 4","key":"144_CR4","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.1053\/j.seminoncol.2006.01.022","volume":"33","author":"RS Cunningham","year":"2006","unstructured":"Cunningham RS. The role of low-molecular-weight heparins as supportive care therapy in cancer-associated thrombosis. Semin Oncol. 2006;33(2 Suppl 4):S17\u201325. quiz S41\u20132.","journal-title":"Semin Oncol"},{"issue":"2","key":"144_CR5","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.ijcard.2004.01.011","volume":"99","author":"H Punukollu","year":"2005","unstructured":"Punukollu H, Khan IA, Punukollu G, Gowda RM, Mendoza C, Sacchi TJ. Acute pulmonary embolism in elderly: clinical characteristics and outcome. Int J Cardiol. 2005;99(2):213\u20136.","journal-title":"Int J Cardiol"},{"issue":"12","key":"144_CR6","doi-asserted-by":"publisher","first-page":"2602","DOI":"10.1111\/jth.12023","volume":"10","author":"AA Khorana","year":"2012","unstructured":"Khorana AA, O\u2019Connell C, Agnelli G, Liebman HA, Lee AY, Subcommittee on H, et al. Incidental venous thromboembolism in oncology patients. J Thromb Haemost. 2012;10(12):2602\u20134.","journal-title":"J Thromb Haemost"},{"issue":"12","key":"144_CR7","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1164\/rccm.201212-2219OC","volume":"187","author":"PL den Exter","year":"2013","unstructured":"den Exter PL, van Es J, Erkens PM, van Roosmalen MJ, van den Hoven P, Hovens MM, et al. Impact of delay in clinical presentation on the diagnostic management and prognosis of patients with suspected pulmonary embolism. Am J Respir Crit Care Med. 2013;187(12):1369\u201373.","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"144_CR8","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1378\/chest.09-0959","volume":"137","author":"SB Smith","year":"2010","unstructured":"Smith SB, Geske JB, Maguire JM, Zane NA, Carter RE, Morgenthaler TI. Early anticoagulation is associated with reduced mortality for acute pulmonary embolism. Chest. 2010;137(6):1382\u201390.","journal-title":"Chest"},{"issue":"8","key":"144_CR9","doi-asserted-by":"publisher","first-page":"1500","DOI":"10.1111\/j.1538-7836.2011.04388.x","volume":"9","author":"W Zondag","year":"2011","unstructured":"Zondag W, Mos IC, Creemers-Schild D, Hoogerbrugge AD, Dekkers OM, Dolsma J, et al. Outpatient treatment in patients with acute pulmonary embolism: the Hestia Study. J Thromb Haemost. 2011;9(8):1500\u20137.","journal-title":"J Thromb Haemost"},{"issue":"5","key":"144_CR10","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/j.annemergmed.2012.05.041","volume":"60","author":"DR Vinson","year":"2012","unstructured":"Vinson DR, Zehtabchi S, Yealy DM. Can selected patients with newly diagnosed pulmonary embolism be safely treated without hospitalization? A systematic review. Ann Emerg Med. 2012;60(5):651\u201362. e4.","journal-title":"Ann Emerg Med"},{"issue":"6","key":"144_CR11","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1016\/j.thromres.2010.03.016","volume":"125","author":"F Dentali","year":"2010","unstructured":"Dentali F, Ageno W, Becattini C, Galli L, Gianni M, Riva N, et al. Prevalence and clinical history of incidental, asymptomatic pulmonary embolism: a meta-analysis. Thromb Res. 2010;125(6):518\u201322.","journal-title":"Thromb Res"},{"issue":"2 Suppl","key":"144_CR12","doi-asserted-by":"publisher","first-page":"e419S","DOI":"10.1378\/chest.11-2301","volume":"141","author":"C Kearon","year":"2012","unstructured":"Kearon C, Akl EA, Comerota AJ, Prandoni P, Bounameaux H, Goldhaber SZ, et al. Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2 Suppl):e419S\u201394S.","journal-title":"Chest"},{"issue":"7","key":"144_CR13","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1002\/cncr.25714","volume":"117","author":"GH Lyman","year":"2011","unstructured":"Lyman GH. Venous thromboembolism in the patient with cancer: focus on burden of disease and benefits of thromboprophylaxis. Cancer. 2011;117(7):1334\u201349.","journal-title":"Cancer"},{"issue":"5","key":"144_CR14","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1111\/bjh.13556","volume":"170","author":"HG Watson","year":"2015","unstructured":"Watson HG, Keeling DM, Laffan M, Tait RC, Makris M, British Committee for Standards in H. Guideline on aspects of cancer-related venous thrombosis. Br J Haematol. 2015;170(5):640\u20138.","journal-title":"Br J Haematol"},{"issue":"4","key":"144_CR15","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1001\/archinte.166.4.458","volume":"166","author":"HK Chew","year":"2006","unstructured":"Chew HK, Wun T, Harvey D, Zhou H, White RH. Incidence of venous thromboembolism and its effect on survival among patients with common cancers. Arch Intern Med. 2006;166(4):458\u201364.","journal-title":"Arch Intern Med"},{"issue":"23 Suppl 1","key":"144_CR16","first-page":"I17","volume":"107","author":"AY Lee","year":"2003","unstructured":"Lee AY, Levine MN. Venous thromboembolism and cancer: risks and outcomes. Circulation. 2003;107(23 Suppl 1):I17\u201321.","journal-title":"Circulation"},{"issue":"19","key":"144_CR17","doi-asserted-by":"publisher","first-page":"1240","DOI":"10.1056\/NEJM199205073261902","volume":"326","author":"JL Carson","year":"1992","unstructured":"Carson JL, Kelley MA, Duff A, Weg JG, Fulkerson WJ, Palevsky HI, et al. The clinical course of pulmonary embolism. N Engl J Med. 1992;326(19):1240\u20135.","journal-title":"N Engl J Med"},{"issue":"25","key":"144_CR18","doi-asserted-by":"publisher","first-page":"1846","DOI":"10.1056\/NEJM200012213432504","volume":"343","author":"HT Sorensen","year":"2000","unstructured":"Sorensen HT, Mellemkjaer L, Olsen JH, Baron JA. Prognosis of cancers associated with venous thromboembolism. N Engl J Med. 2000;343(25):1846\u201350.","journal-title":"N Engl J Med"},{"key":"144_CR19","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-3-319-26387-8_1","volume-title":"Oncologic Emergency Medicine: Principles and Practice","author":"TW Rice","year":"2016","unstructured":"Rice TW, Klotz A, Neville-Webbe HL, Ahn S, Adkins EJ. Models of care for cancer emergencies. In: Todd KH, Thomas CRJ, editors. Oncologic Emergency Medicine: Principles and Practice. Switzerland: Springer International Publishing; 2016. p. 3\u201312."},{"key":"144_CR20","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.ienj.2015.05.007","volume":"24","author":"M Oatley","year":"2016","unstructured":"Oatley M, Fry M, Mullen L. A cross-sectional study of the clinical characteristics of cancer patients presenting to one tertiary referral emergency department. Int Emerg Nurs. 2016;24:35\u20138.","journal-title":"Int Emerg Nurs"},{"issue":"6","key":"144_CR21","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1136\/thorax.58.6.470","volume":"58","author":"British Thoracic Society Standards of Care Committee Pulmonary Embolism Guideline Development G","year":"2003","unstructured":"British Thoracic Society Standards of Care Committee Pulmonary Embolism Guideline Development G. British Thoracic Society guidelines for the management of suspected acute pulmonary embolism. Thorax. 2003;58(6):470\u201383.","journal-title":"Thorax"},{"issue":"3","key":"144_CR22","doi-asserted-by":"publisher","first-page":"204","DOI":"10.7326\/0003-4819-146-3-200702060-00149","volume":"146","author":"V Snow","year":"2007","unstructured":"Snow V, Qaseem A, Barry P, Hornbake ER, Rodnick JE, Tobolic T, et al. Management of venous thromboembolism: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Ann Intern Med. 2007;146(3):204\u201310.","journal-title":"Ann Intern Med"},{"issue":"11","key":"144_CR23","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1111\/acem.13072","volume":"23","author":"AJ Singer","year":"2016","unstructured":"Singer AJ, Xiang J, Kabrhel C, Merli GJ, Pollack C, Tapson VF, et al. Multicenter trial of rivaroxaban for early discharge of pulmonary embolism from the emergency department (MERCURY PE): rationale and design. Acad Emerg Med. 2016;23(11):1280\u20136.","journal-title":"Acad Emerg Med"},{"key":"144_CR24","unstructured":"American Cancer Society. Cancer Facts & Figures 2016. Available from: \n                    http:\/\/www.cancer.org\/acs\/groups\/content\/@research\/documents\/document\/acspc-047079.pdf\n                    \n                  . Accessed 18 Nov 2016."},{"issue":"2","key":"144_CR25","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1093\/jnci\/djq495","volume":"103","author":"AB Mariotto","year":"2011","unstructured":"Mariotto AB, Yabroff KR, Shao Y, Feuer EJ, Brown ML. Projections of the cost of cancer care in the United States: 2010\u20132020. J Natl Cancer Inst. 2011;103(2):117\u201328.","journal-title":"J Natl Cancer Inst"},{"issue":"4","key":"144_CR26","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1007\/s11739-014-1066-7","volume":"9","author":"MP Donadini","year":"2014","unstructured":"Donadini MP, Dentali F, Squizzato A, Guasti L, Ageno W. Unsuspected pulmonary embolism in cancer patients: a narrative review with pooled data. Intern Emerg Med. 2014;9(4):375\u201384.","journal-title":"Intern Emerg Med"},{"issue":"1","key":"144_CR27","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.crad.2005.09.002","volume":"61","author":"AJ Sebastian","year":"2006","unstructured":"Sebastian AJ, Paddon AJ. Clinically unsuspected pulmonary embolism\u2014an important secondary finding in oncology CT. Clin Radiol. 2006;61(1):81\u20135.","journal-title":"Clin Radiol"},{"issue":"3","key":"144_CR28","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/S0196-0644(96)70264-0","volume":"27","author":"EH Gilbert","year":"1996","unstructured":"Gilbert EH, Lowenstein SR, Koziol-McLain J, Barta DC, Steiner J. Chart reviews in emergency medicine research: where are the methods? Ann Emerg Med. 1996;27(3):305\u20138.","journal-title":"Ann Emerg Med"},{"issue":"4","key":"144_CR29","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.annemergmed.2004.11.021","volume":"45","author":"A Worster","year":"2005","unstructured":"Worster A, Bledsoe RD, Cleve P, Fernandes CM, Upadhye S, Eva K. Reassessing the methods of medical record review studies in emergency medicine research. Ann Emerg Med. 2005;45(4):448\u201351.","journal-title":"Ann Emerg Med"},{"issue":"6","key":"144_CR30","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1097\/00000421-198212000-00014","volume":"5","author":"MM Oken","year":"1982","unstructured":"Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5(6):649\u201355.","journal-title":"Am J Clin Oncol"},{"issue":"11","key":"144_CR31","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/0895-4356(94)90129-5","volume":"47","author":"M Charlson","year":"1994","unstructured":"Charlson M, Szatrowski TP, Peterson J, Gold J. Validation of a combined comorbidity index. J Clin Epidemiol. 1994;47(11):1245\u201351.","journal-title":"J Clin Epidemiol"},{"issue":"3","key":"144_CR32","doi-asserted-by":"publisher","first-page":"126","DOI":"10.15441\/ceem.15.096","volume":"3","author":"AJ Singer","year":"2016","unstructured":"Singer AJ, Thode Jr HC, Peacock WF. Admission rates for emergency department patients with venous thromboembolism and estimation of the proportion of low risk pulmonary embolism patients: a US perspective. Clin Exp Emerg Med. 2016;3(3):126\u201331.","journal-title":"Clin Exp Emerg Med"},{"issue":"11","key":"144_CR33","doi-asserted-by":"publisher","first-page":"2412","DOI":"10.1111\/j.1538-7836.2010.04041.x","volume":"8","author":"PM Erkens","year":"2010","unstructured":"Erkens PM, Gandara E, Wells P, Shen AY, Bose G, Le Gal G, et al. Safety of outpatient treatment in acute pulmonary embolism. J Thromb Haemost. 2010;8(11):2412\u20137.","journal-title":"J Thromb Haemost"},{"issue":"11","key":"144_CR34","doi-asserted-by":"publisher","first-page":"2406","DOI":"10.1111\/j.1538-7836.2010.03981.x","volume":"8","author":"MJ Kovacs","year":"2010","unstructured":"Kovacs MJ, Hawel JD, Rekman JF, Lazo-Langner A. Ambulatory management of pulmonary embolism: a pragmatic evaluation. J Thromb Haemost. 2010;8(11):2406\u201311.","journal-title":"J Thromb Haemost"},{"issue":"47\u201348","key":"144_CR35","first-page":"685","volume":"139","author":"D Aujesky","year":"2009","unstructured":"Aujesky D, Mazzolai L, Hugli O, Perrier A. Outpatient treatment of pulmonary embolism. Swiss Med Wkly. 2009;139(47\u201348):685\u201390.","journal-title":"Swiss Med Wkly"},{"issue":"3","key":"144_CR36","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1378\/chest.128.3.1601","volume":"128","author":"D Aujesky","year":"2005","unstructured":"Aujesky D, Smith KJ, Cornuz J, Roberts MS. Cost-effectiveness of low-molecular-weight heparin for treatment of pulmonary embolism. Chest. 2005;128(3):1601\u201310.","journal-title":"Chest"},{"key":"144_CR37","first-page":"CD007491","volume":"4","author":"S Shepperd","year":"2008","unstructured":"Shepperd S, Doll H, Angus RM, Clarke MJ, Iliffe S, Kalra L, et al. Admission avoidance hospital at home. Cochrane Database Syst Rev. 2008;4:CD007491.","journal-title":"Cochrane Database Syst Rev"}],"container-title":["International Journal of Emergency Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12245-017-0144-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12245-017-0144-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12245-017-0144-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T17:34:43Z","timestamp":1589650483000},"score":1,"resource":{"primary":{"URL":"https:\/\/intjem.biomedcentral.com\/articles\/10.1186\/s12245-017-0144-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,6]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["144"],"URL":"https:\/\/doi.org\/10.1186\/s12245-017-0144-9","relation":{},"ISSN":["1865-1372","1865-1380"],"issn-type":[{"value":"1865-1372","type":"print"},{"value":"1865-1380","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,6]]},"assertion":[{"value":"17 March 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 June 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"19"}}