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Information on patient characteristics, isolated\n                      <jats:italic>Candida<\/jats:italic>\n                      species, treatment details for candidemia, and ocular findings were extracted to identify factors associated with OC development.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The leading pathogen of candidemia was\n                      <jats:italic>Candida albicans\u00a0(C.albicans)<\/jats:italic>\n                      (41.1%). Of 56 patients, 18 (32.1%) were diagnosed with chorioretinitis, categorized as either probable (8 patients) or possible OC (10 patients). There was no case of endophthalmitis with vitritis. The incidence of probable OC was not significantly different between the groups treated with echinocandins and other antifungal drugs (15.2% vs. 11.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.00). In all probable OC cases, systemic antifungal therapy was switched from echinocandins to azoles, and no case progressed to endophthalmitis. A multivariate logistic analysis revealed that female sex (adjusted odds ratio [aOR], 8.93; 95% confidence interval [CI], 1.09\u201372.9) and\n                      <jats:italic>C. albicans<\/jats:italic>\n                      (aOR, 23.6; 95% CI, 1.8\u2013281) were independent factors associated with the development of probable OC.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      One-seventh of patients with candidemia developed probable OC. Given the evidence of female and\n                      <jats:italic>C. albicans<\/jats:italic>\n                      as the factors associated with OC development, careful ophthalmologic management is required with these factors, especially in candidemia. Although echinocandins had no correlation with OC development and did not lead to the deterioration of ocular prognosis, further investigation is required.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12348-021-00248-0","type":"journal-article","created":{"date-parts":[[2021,6,13]],"date-time":"2021-06-13T19:03:41Z","timestamp":1623611021000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Factors associated with the development of ocular candidiasis and ocular prognosis with echinocandin therapy for candidemia"],"prefix":"10.1186","volume":"11","author":[{"given":"Daiki","family":"Sakai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3495-7460","authenticated-orcid":false,"given":"Wataru","family":"Matsumiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sentaro","family":"Kusuhara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,14]]},"reference":[{"issue":"5","key":"248_CR1","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.jinf.2009.08.020","volume":"59","author":"I Hassan","year":"2009","unstructured":"Hassan I, Powell G, Sidhu M, Hart WM, Denning DW (2009) Excess mortality, length of stay and cost attributable to candidaemia. 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