{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T18:07:17Z","timestamp":1781546837918,"version":"3.54.5"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ophthal Inflamm Infect"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>Corneal ulcers frequently result in ocular morbidity and may lead to permanent visual impairment if severe or untreated. This study aims to evaluate the association of patient factors and ocular exam findings on clinical outcomes for patients diagnosed with a corneal ulcer at a tertiary care center in the Bronx, New York.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A retrospective chart review was conducted on all ambulatory and admitted patients diagnosed with a corneal ulcer (identified using ICD-10 code H16.0) at Montefiore Medical Center, Bronx, NY between 2016\u20132022. Patient demographics, presence of known risk factors, characteristics of subsequent clinical course, and microbiological studies were noted. Clinical outcomes following treatment were longitudinally evaluated and categorized based upon the following criteria: 1) \u2018No Surgical Intervention\u2019: No severe complications or surgery required after presentation, 2) \u2018Surgical Intervention\u2019: Decline in BCVA with surgery required for a severe complication.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The search criteria identified 205 patients (205 eyes) with the diagnosis of a corneal ulcer. Mean age was 55.3\u2009\u00b1\u200921.1\u00a0years (mean\u2009\u00b1\u2009SD). Mean ulcer area at presentation was 7\u2009\u00b1\u200910.5 mm<jats:sup>2<\/jats:sup>. Mean LogMAR at presentation was 1.2\u2009\u00b1\u20091, and following treatment, improved to 1.0\u2009\u00b1\u20091. \u2018Surgical Intervention\u2019 outcome was associated with advanced age (<jats:italic>p<\/jats:italic>\u2009=\u20090.005), presence of ocular surface disease (<jats:italic>p<\/jats:italic>\u2009=\u20090.008), central location of ulcer (<jats:italic>p<\/jats:italic>\u2009=\u20090.014), greater ulcer area at presentation (<jats:italic>p<\/jats:italic>\u2009=\u20090.003), worse visual acuity at presentation (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and isolation of fungi (<jats:italic>p<\/jats:italic>\u2009=\u20090.004).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Identification of risk factors associated with a poor clinical prognosis can guide treatment and inform expectations for patients diagnosed with a corneal ulcer. Our study highlights the importance of timely diagnosis, work-up, and initiation of appropriate management, particularly in vulnerable populations where access to specialty care is logistically challenging.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12348-024-00392-3","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T15:01:59Z","timestamp":1713970919000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Prognostic indicators of corneal ulcer clinical outcomes at a tertiary care center in the Bronx, New York"],"prefix":"10.1186","volume":"14","author":[{"given":"Sruthi","family":"Kodali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Behram","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda M.","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jee-Young","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anurag","family":"Shrivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna P.","family":"Daily","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard P.","family":"Gibralter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"issue":"3","key":"392_CR1","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/j.pop.2015.05.004","volume":"42","author":"F Ahmed","year":"2015","unstructured":"Ahmed F, House RJ, Feldman BH (2015) Corneal Abrasions and Corneal Foreign Bodies. 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