{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T10:45:55Z","timestamp":1746009955756},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T00:00:00Z","timestamp":1728864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T00:00:00Z","timestamp":1728864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ophthal Inflamm Infect"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Orbital tuberculosis is a rare form of extra pulmonary TB and may arise either by hematogenous route or spread directly from the paranasal sinus. We herein report two cases of orbital TB with a vision threatening complication. Case-1 is a 31-year-old female with a headache, a diminution of vision in the right eye, and pain in ocular movement. On examination, there was no proptosis with RAPD present in right eye and tenderness on palpation. CEMRI revealed a diffuse infiltrating lesion at the orbital apex, suggesting of inflammatory pathology. Case-2 is a 40-year-old male with similar complaints in the left eye, CECT showed edema and swelling in the optic nerve and extraocular muscle of the left eye. A detailed investigation was done, and a diagnosis of orbital tuberculosis was made in both patients. They were started on ATT and oral steroids but lost follow-up initially and due to delayed treatment, it led to irreversible vision loss. A long-term follow-up showed resolution of ocular symptoms with occasional headaches.<\/jats:p>","DOI":"10.1186\/s12348-024-00425-x","type":"journal-article","created":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T10:02:15Z","timestamp":1728900135000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Orbital tuberculosis presenting as vision loss and headache: early management is paramount"],"prefix":"10.1186","volume":"14","author":[{"given":"Sandeep","family":"Pal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narendra","family":"Patidar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunjan","family":"Tomar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himanshu","family":"Gaikwad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,14]]},"reference":[{"key":"425_CR1","unstructured":"Ocular Tuberculosis (TB) - Asia Pacific [Internet], American Academy of Ophthalmology. 2014 [cited 2023 Oct 15]. Available from: https:\/\/www.aao.org\/education\/topic-detail\/ocular-tuberculosis-tb--asia-pacific-2"},{"key":"425_CR2","doi-asserted-by":"publisher","unstructured":"Badakere A, Patil- Chhablani P (2019) Orbital apex syndrome: A review. Eye Brain [Internet]. 11:63\u201372. Available from: https:\/\/doi.org\/10.2147\/eb.s180190","DOI":"10.2147\/eb.s180190"},{"key":"425_CR3","doi-asserted-by":"publisher","unstructured":"Hughes EH, Petrushkin H, Sibtain NA, Stanford MR, Plant GT, Graham EM (2008) Tuberculous orbital apex syndromes. Br J Ophthalmol [Internet]. 92(11):1511\u20137. Available from: https:\/\/doi.org\/10.1136\/bjo.2008.138974","DOI":"10.1136\/bjo.2008.138974"},{"key":"425_CR4","doi-asserted-by":"publisher","unstructured":"Tanawade RG, Thampy RS, Wilson S, Lloyd IC, Ashworth J (2015) Tuberculous orbital apex syndrome with severe irreversible visual loss. Orbit [Internet]. 34(3):172\u20134. Available from: https:\/\/doi.org\/10.3109\/01676830.2015.1014505","DOI":"10.3109\/01676830.2015.1014505"},{"key":"425_CR5","doi-asserted-by":"publisher","unstructured":"Babu K, Mukhopadhyay M, Bhat SS, Chinmayee JT (2014) Orbital and adnexal tuberculosis: a case series from a South Indian population. J Ophthalmic Inflamm Infect [Internet]. 4(1):12. Available from: https:\/\/doi.org\/10.1186\/1869-5760-4-12","DOI":"10.1186\/1869-5760-4-12"},{"key":"425_CR6","doi-asserted-by":"publisher","unstructured":"Nayak S, Acharjya B (2012) Mantoux test and its interpretation. Indian Dermatol Online J [Internet]. 3(1):2. Available from: https:\/\/doi.org\/10.4103\/2229-5178.93479","DOI":"10.4103\/2229-5178.93479"},{"key":"425_CR7","doi-asserted-by":"publisher","unstructured":"Shah I, Kathwate J, Shetty N (2020) Comparison of tuberculin skin test and QuantiFERON-TB Gold In-Tube test in Bacillus Calmette\u2013Guerin-vaccinated children. Lung India [Internet]. 37(1):24. Available from: https:\/\/doi.org\/10.4103\/lungindia.lungindia_304_19","DOI":"10.4103\/lungindia.lungindia_304_19"}],"container-title":["Journal of Ophthalmic Inflammation and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12348-024-00425-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12348-024-00425-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12348-024-00425-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T10:03:12Z","timestamp":1728900192000},"score":1,"resource":{"primary":{"URL":"https:\/\/joii-journal.springeropen.com\/articles\/10.1186\/s12348-024-00425-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,14]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["425"],"URL":"https:\/\/doi.org\/10.1186\/s12348-024-00425-x","relation":{},"ISSN":["1869-5760"],"issn-type":[{"value":"1869-5760","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,14]]},"assertion":[{"value":"24 December 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval is not required for this case report in accordance with local and national guidelines.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written Informed consent was obtained from the patient in question to publish their medical case and accompanying images.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"51"}}