{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T15:40:12Z","timestamp":1729784412872,"version":"3.28.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T00:00:00Z","timestamp":1729728000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Beijing Natural Science Foundation","award":["7212016"],"award-info":[{"award-number":["7212016"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Ophthal Inflamm Infect"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To evaluate the safety and efficacy of intravitreal dexamethasone implantation during phacoemulsification and intraocular lens implantation in pediatric uveitis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A retrospective analysis was conducted on pediatric uveitis patients undergoing phacoemulsification and intraocular lens implantation with intravitreal dexamethasone implantation. Patients with a minimum follow-up of 6 months were included. Primary outcome measures included ocular inflammation, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and worsening of uveitis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>36 eyes of 28 patients were ultimately included in this study. The mean preoperative BCVA was 1.00 (0.40\u20131.50) LogMAR. BCVA significantly improved to 0.40 (0.20\u20130.54) LogMAR at 1 month postoperatively (<jats:italic>P<\/jats:italic>\u2009=\u20090.006), further improving to 0.30 (0.20\u20130.40) LogMAR at 3 months postoperatively (<jats:italic>P<\/jats:italic>\u2009=\u20090.001). BCVA remained stable at 0.30 (0.20\u20130.70) LogMAR at 6 months postoperatively (<jats:italic>P<\/jats:italic>\u2009=\u20090.005). Mean IOP showed no statistically significant difference during the follow-up period of three to six months after surgery. Eight children experienced recurrence of ocular inflammation during the 6-month follow-up period. No cases of worsening macular edema, glaucoma, or elevated IOP were observed in any patient.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Intravitreal dexamethasone implantation during phacoemulsification and intraocular lens implantation is a safe and effective method for preventing and treating postoperative inflammation in children with uveitis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12348-024-00440-y","type":"journal-article","created":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T15:03:09Z","timestamp":1729782189000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Safety and efficacy of intravitreal dexamethasone implantation along with phacoemulsification and intraocular lens implantation in children with uveitis"],"prefix":"10.1186","volume":"14","author":[{"given":"Hui","family":"Feng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weixin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianzhu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haorong","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Mo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,10,24]]},"reference":[{"key":"440_CR1","doi-asserted-by":"publisher","unstructured":"de Boer J, Wulffraat N, Rothova A (Jul 2003) Visual loss in uveitis of childhood[Br J Ophthalmol. 87(7):879\u2013884. https:\/\/doi.org\/10.1136\/bjo.87.7.879","DOI":"10.1136\/bjo.87.7.879"},{"issue":"6","key":"440_CR2","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.preteyeres.2011.06.005","volume":"30","author":"MD de Smet","year":"2011","unstructured":"de Smet MD, Taylor SR, Bodaghi B et al (2011) Understanding uveitis: the impact of research on visual outcomes[. 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All patients provided written informed consent to use their data for analysis and publication. Written informed consent was obtained from adult patients and their parents or legal guardians before enrollment.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All patients or legal guardians provided written informed consent to use their data for analysis and publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"55"}}