{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:06:29Z","timestamp":1790129189616,"version":"4.0.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":82,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/100008127","name":"DePuy Synthes","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008127","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Biol Proced Online"],"DOI":"10.1186\/s12575-026-00350-4","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:03:59Z","timestamp":1783040639000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Comparison of Two Rabbit Tibiofemoral Joint Replacement Models"],"prefix":"10.1186","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9784-4693","authenticated-orcid":false,"given":"Bailey V.","family":"Fearing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah M.","family":"Romereim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Smykowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Eddie","family":"Afetse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aatif A.","family":"Jabbar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth W.","family":"Sloop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerry","family":"A. Danelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse E.","family":"Otero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"issue":"17","key":"350_CR1","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.2106\/JBJS.17.01617","volume":"100","author":"M Sloan","year":"2018","unstructured":"Sloan M, Premkumar A, Sheth NP. Projected Volume of Primary Total Joint Arthroplasty in the U.S., 2014 to 2030. J Bone Joint Surg Am. 2018;100(17):1455\u201360.","journal-title":"J Bone Joint Surg Am"},{"key":"350_CR2","doi-asserted-by":"publisher","unstructured":"Day CW, Costi K, Pannach S, Atkins GJ, Hofstaetter JG, Callary SA et al. Long-Term Outcomes of Staged Revision Surgery for Chronic Periprosthetic Joint Infection of Total Hip Arthroplasty. J Clin Med. 2021;11(1):122. https:\/\/doi.org\/10.3390\/jcm11010122","DOI":"10.3390\/jcm11010122"},{"issue":"24","key":"350_CR3","doi-asserted-by":"publisher","first-page":"2177","DOI":"10.2106\/JBJS.L.00789","volume":"95","author":"B Zmistowski","year":"2013","unstructured":"Zmistowski B, Karam JA, Durinka JB, Casper DS, Parvizi J. Periprosthetic joint infection increases the risk of one-year mortality. JBJS. 2013;95(24):2177\u201384.","journal-title":"JBJS"},{"key":"350_CR4","doi-asserted-by":"crossref","unstructured":"Parvizi J, Gehrke T, Chen AF. Proceedings of the International Consensus on Periprosthetic Joint Infection. Bone Joint J. 2013;95-B(11):1450-2.","DOI":"10.1302\/0301-620X.95B11.33135"},{"issue":"6","key":"350_CR5","doi-asserted-by":"publisher","first-page":"e25","DOI":"10.2106\/JBJS.16.00815","volume":"99","author":"AV Carli","year":"2017","unstructured":"Carli AV, Bhimani S, Yang X, Shirley MB, de Mesy Bentley KL, Ross FP, et al. Quantification of Peri-implant Bacterial Load and in vivo Biofilm Formation in an Innovative, Clinically Representative Mouse Model of Periprosthetic Joint Infection. JBJS. 2017;99(6):e25.","journal-title":"JBJS"},{"issue":"5","key":"350_CR6","doi-asserted-by":"publisher","first-page":"1100","DOI":"10.1016\/j.orthres.2005.03.007","volume":"23","author":"MR Craig","year":"2005","unstructured":"Craig MR, Poelstra KA, Sherrell JC, Kwon MS, Belzile EL, Brown TE. A Novel Total Knee Arthroplasty Infection Model in Rabbits. J Orthop Res. 2005;23(5):1100\u20134.","journal-title":"J Orthop Res"},{"key":"350_CR7","volume-title":"Staphylococcus Epidermidis Methods in Molecular Biology [Internet]","author":"TD Scherr","year":"2014","unstructured":"Scherr TD, Lindgren KE, Schaeffer CR, Hanke ML, Hartman CW, Kielian T. Mouse Model of Post-arthroplasty Staphylococcus epidermidis Joint Infection. Staphylococcus Epidermidis Methods in Molecular Biology. Totowa, NJ: Humana; 2014."},{"key":"350_CR8","volume-title":"Animal Models in Orthopaedic Research","author":"DR Sumner","year":"1998","unstructured":"Sumner DR, Turner TM, Urban RM. Animal Models for Studying Bone Ingrowth and Joint Replacement. In: An Y, Friedman R, editors. Animal Models in Orthopaedic Research. Boca Raton, FL: CRC; 1998."},{"issue":"2","key":"350_CR9","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1093\/infdis\/174.2.414","volume":"174","author":"N Belmatoug","year":"1996","unstructured":"Belmatoug N, Cremieux AC, Bleton R, Volk A, Saleh-Mghir A, Grossin M, et al. A New Model of Experimental Prosthetic Joint Infection Due to Methicillin-resistant Staphylococcus Aureus: A Microbiologic, Histopathologic, and Magnetic Resonance Imaging Characterization. J Infect Dis. 1996;174(2):414\u20137.","journal-title":"J Infect Dis"},{"issue":"7","key":"350_CR10","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1016\/j.otsr.2015.08.007","volume":"101","author":"L Gatin","year":"2015","unstructured":"Gatin L, Saleh-Mghir A, Massin P, Cremieux AC. Critical Analysis of Experimental Models of Periprosthetic Joint Infection. Orthop Traumatol Surg Res. 2015;101(7):851\u20135.","journal-title":"Orthop Traumatol Surg Res"},{"issue":"1","key":"350_CR11","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1186\/s12917-020-02451-y","volume":"16","author":"N Percie du Sert","year":"2020","unstructured":"Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, et al. The ARRIVE guidelines 2.0: Updated Guidelines for Reporting Animal Research. BMC Vet Res. 2020;16(1):242.","journal-title":"BMC Vet Res"},{"issue":"4","key":"350_CR12","doi-asserted-by":"publisher","first-page":"510","DOI":"10.30802\/AALAS-JAALAS-18-000116","volume":"58","author":"KA Bartley","year":"2019","unstructured":"Bartley KA, Johnson CH. Human Infant Pants for Postoperative Protection during Social Housing of New Zealand White Rabbits (Oryctolagus cuniculus). J Am Assoc Lab Anim Sci. 2019;58(4):510\u20136.","journal-title":"J Am Assoc Lab Anim Sci"},{"issue":"10","key":"350_CR13","doi-asserted-by":"publisher","first-page":"4589","DOI":"10.1128\/AAC.00675-11","volume":"55","author":"A Saleh-Mghir","year":"2011","unstructured":"Saleh-Mghir A, Muller-Serieys C, Dinh A, Massias L, Cremieux AC. Adjunctive Rifampin is Crucial to Optimizing Daptomycin Efficacy Against Rabbit Prosthetic Joint Infection Due to Methicillin-resistant Staphylococcus Aureus. Antimicrob Agents Chemother. 2011;55(10):4589\u201393.","journal-title":"Antimicrob Agents Chemother"},{"key":"350_CR14","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1186\/1749-799X-8-25","volume":"8","author":"V Zampelis","year":"2013","unstructured":"Zampelis V, Tagil M, Lidgren L, Isaksson H, Atroshi I, Wang JS. The Effect of a Biphasic Injectable Bone Substitute on the Interface Strength in a Rabbit Knee Prosthesis Model. J Orthop Surg Res. 2013;8:25.","journal-title":"J Orthop Surg Res"},{"issue":"1","key":"350_CR15","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s42826-022-00128-1","volume":"38","author":"P Mukherjee","year":"2022","unstructured":"Mukherjee P, Roy S, Ghosh D, Nandi SK. Role of Animal Models in Biomedical Research: A Review. Lab Anim Res. 2022;38(1):18.","journal-title":"Lab Anim Res"},{"key":"350_CR16","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1097\/01.blo.0000214417.29335.19","volume":"446","author":"KI Kim","year":"2006","unstructured":"Kim KI, Egol KA, Hozack WJ, Parvizi J. Periprosthetic Fractures After Total Knee Arthroplasties. Clin Orthop Relat Res. 2006;446:167\u201375.","journal-title":"Clin Orthop Relat Res"}],"container-title":["Biological Procedures Online"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12575-026-00350-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12575-026-00350-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12575-026-00350-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:51:33Z","timestamp":1790128293000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12575-026-00350-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,3]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["350"],"URL":"https:\/\/doi.org\/10.1186\/s12575-026-00350-4","relation":{},"ISSN":["1480-9222"],"issn-type":[{"value":"1480-9222","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,3]]},"assertion":[{"value":"23 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 June 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Ethical approval of the study protocols (11-20-01\u00a0A, A21-065, and A24-160) was received from the Institutional Animal Care and Use Committee. All methods were performed in accordance with the relevant guidelines and regulations of the ethics committee.","order":1,"name":"Ethics","label":"Ethics Approval and Consent to Participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Note applicable.","order":2,"name":"Ethics","label":"Consent for Publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Dr. Otero is a paid consultant of DePuy Synthes.","order":3,"name":"Ethics","label":"Competing Interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"35"}}