{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:52:38Z","timestamp":1791420758211,"version":"4.3.3"},"reference-count":61,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":91,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Physiological Sciences"],"published-print":{"date-parts":[[2024]]},"DOI":"10.1186\/s12576-024-00908-5","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T07:01:43Z","timestamp":1711954903000},"page":"22","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Acetate ameliorates ovarian mitochondrial dysfunction in letrozole-induced polycystic ovarian syndrome rat model by improving mitofusin-2"],"prefix":"10.1016","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8229-9688","authenticated-orcid":false,"given":"Kehinde S.","family":"Olaniyi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie E.","family":"Areloegbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1186\/s12576-024-00908-5_bb0010","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1007\/s10815-017-1027-y","article-title":"CoQ10 increases mitochondrial mass and polarization, ATP and Oct4 potency levels, and bovine oocyte MII during IVM while decreasing AMPK activity and oocyte death","volume":"34","author":"Abdulhasan","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"10.1186\/s12576-024-00908-5_bb0015","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.abb.2019.06.009","article-title":"Therapeutic potential of sodium selenite in letrozole induced polycystic ovary syndrome rat model: targeting mitochondrial approach (selenium in PCOS)","volume":"671","author":"Atef","year":"2019","journal-title":"Arch Biochem Biophys"},{"issue":"6","key":"10.1186\/s12576-024-00908-5_bb0020","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1093\/humrep\/deac049","article-title":"Candidate genes for polycystic ovary syndrome are regulated by TGF\u03b2 in the bovine foetal ovary","volume":"37","author":"Azumah","year":"2022","journal-title":"Hum Reprod"},{"issue":"4","key":"10.1186\/s12576-024-00908-5_bb0025","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/OGX.0000000000000661","article-title":"Polycystic ovary syndrome: impact of lipotoxicity on metabolic and reproductive health","volume":"74","author":"Brennan","year":"2019","journal-title":"Obstet Gynecol Surv"},{"issue":"5","key":"10.1186\/s12576-024-00908-5_bb0030","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1111\/acel.12368","article-title":"Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging","volume":"14","author":"Ben-Meir","year":"2015","journal-title":"Aging Cell"},{"issue":"6","key":"10.1186\/s12576-024-00908-5_bb0035","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1093\/molehr\/gaw023","article-title":"Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency","volume":"22","author":"Conca Dioguardi","year":"2016","journal-title":"Mol Hum Reprod"},{"key":"10.1186\/s12576-024-00908-5_bb0040","first-page":"520","article-title":"Polycystic ovary syndrome and hyperandrogenic states","author":"Chang","year":"2019"},{"issue":"2","key":"10.1186\/s12576-024-00908-5_bb0045","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1007\/s43032-022-01014-w","article-title":"Targeted deletion of mitofusin 1 and mitofusin 2 causes female infertility and loss of follicular reserve","volume":"30","author":"Cozzolino","year":"2023","journal-title":"Reprod Sci"},{"issue":"9","key":"10.1186\/s12576-024-00908-5_bb0050","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1194\/jlr.R036012","article-title":"The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism","volume":"54","author":"Den","year":"2013","journal-title":"J Lipid Res"},{"key":"10.1186\/s12576-024-00908-5_bb0055","doi-asserted-by":"crossref","first-page":"108929","DOI":"10.1016\/j.cbi.2019.108929","article-title":"Sodium acetate protects against nicotine-induced excess hepatic lipid in male rats by suppressing xanthine oxidase activity","volume":"316","author":"Dangana","year":"2020","journal-title":"Chem Biol Interact"},{"issue":"10","key":"10.1186\/s12576-024-00908-5_bb0060","first-page":"13","article-title":"Effect of infertility on the quality of life, a cross-sectional study","volume":"8","author":"Direkvand-Moghadam","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"10.1186\/s12576-024-00908-5_bb0065","doi-asserted-by":"crossref","first-page":"782","DOI":"10.3389\/fphys.2020.00782","article-title":"Mitofusin 2 dysfunction and disease in mice and men","volume":"11","author":"Dorn","year":"2020","journal-title":"Front Physiol"},{"key":"10.1186\/s12576-024-00908-5_bb0070","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.coemr.2020.02.013","article-title":"Endocrine\u2013metabolic dysfunction in polycystic ovary syndrome: an evolutionary perspective","volume":"12","author":"Dumesic","year":"2020","journal-title":"Curr Opin Endocr Metab Res"},{"issue":"3","key":"10.1186\/s12576-024-00908-5_bb0075","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1080\/14647273.2016.1214754","article-title":"Effect of infertility on quality of life of women: a validation study of the Turkish FertiQoL","volume":"19","author":"Dural","year":"2016","journal-title":"Hum Fertil"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0080","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/GRF.0b013e31802f35a0","article-title":"Pharmacologic therapy of polycystic ovary syndrome","volume":"50","author":"Dronavalli","year":"2007","journal-title":"Clin Obstet Gynecol"},{"issue":"8","key":"10.1186\/s12576-024-00908-5_bb0085","doi-asserted-by":"crossref","first-page":"E1298","DOI":"10.1210\/jc.2011-0278","article-title":"Intact primary mitochondrial function in myotubes established from women with PCOS","volume":"96","author":"Eriksen","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0090","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/humrep\/deh098","article-title":"Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)","volume":"19","author":"ASRM-Sponsored PCOS Consensus Workshop Group","year":"2004","journal-title":"Hum Reprod"},{"issue":"7","key":"10.1186\/s12576-024-00908-5_bb0095","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1089\/jwh.2017.6833","article-title":"Long-term response of hirsutism and other hyperandrogenic symptoms to combination therapy in polycystic ovary syndrome","volume":"27","author":"Ezeh","year":"2018","journal-title":"J Womens Health"},{"key":"10.1186\/s12576-024-00908-5_bb0100","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.phrs.2018.01.003","article-title":"Highlighting the endoplasmic reticulum\u2013mitochondria connection: focus on Mitofusin 2","volume":"128","author":"Filadi","year":"2018","journal-title":"Pharmacol Res"},{"key":"10.1186\/s12576-024-00908-5_bb0105","doi-asserted-by":"crossref","first-page":"452","DOI":"10.3389\/fendo.2018.00452","article-title":"Androgen action in the ovary","volume":"9","author":"Franks","year":"2018","journal-title":"Front Endocrinol"},{"issue":"8","key":"10.1186\/s12576-024-00908-5_bb0110","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.3390\/nu11081943","article-title":"The short-chain fatty acid acetate in body weight control and insulin sensitivity","volume":"11","author":"Gonz\u00e1lez","year":"2019","journal-title":"Nutrients"},{"issue":"2","key":"10.1186\/s12576-024-00908-5_bb0115","first-page":"203","article-title":"Adipocytokines and aging: adiponectin and leptin","volume":"38","author":"Gulcelik","year":"2013","journal-title":"Minerva Endocrinol"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0120","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/jnci\/95.1.67","article-title":"Insulin resistance and prostate cancer risk","volume":"95","author":"Hsing","year":"2003","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"10.1186\/s12576-024-00908-5_bb0125","doi-asserted-by":"crossref","first-page":"731","DOI":"10.3892\/etm.2014.1835","article-title":"Lentivirus vector-mediated mitofusin-2 overexpression in rat ovary changes endocrine function and promotes follicular development in vivo","volume":"8","author":"Hu","year":"2014","journal-title":"Exp Ther Med"},{"issue":"4","key":"10.1186\/s12576-024-00908-5_bb0130","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1093\/humupd\/dmv016","article-title":"Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century","volume":"21","author":"Inhorn","year":"2015","journal-title":"Hum Reprod Update"},{"issue":"7","key":"10.1186\/s12576-024-00908-5_bb0135","first-page":"423","article-title":"Association of leptin and insulin resistance in PCOS: a case-controlled study","volume":"15","author":"Jahromi","year":"2017","journal-title":"Int J Reprod BioMed"},{"issue":"2","key":"10.1186\/s12576-024-00908-5_bb0140","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.arcmed.2003.10.005","article-title":"Letrozole-induced polycystic ovaries in the rat: a new model for cystic ovarian disease","volume":"35","author":"Kafali","year":"2004","journal-title":"Arch Med Res"},{"key":"10.1186\/s12576-024-00908-5_bb0145","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.maturitas.2015.08.015","article-title":"Ovarian infertility is associated with cardiovascular disease risk factors in later life: a Japanese cross-sectional study","volume":"83","author":"Kurabayashi","year":"2016","journal-title":"Maturitas"},{"issue":"8","key":"10.1186\/s12576-024-00908-5_bb0150","doi-asserted-by":"crossref","first-page":"E924","DOI":"10.1152\/ajpendo.00198.2011","article-title":"Amylin improves the effect of leptin on insulin sensitivity in leptin-resistant diet-induced obese mice","volume":"302","author":"Kusakabe","year":"2012","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0155","doi-asserted-by":"crossref","first-page":"30561","DOI":"10.1038\/srep30561","article-title":"Mitofusin 2 regulates the oocytes development and quality by modulating meiosis and mitochondrial function","volume":"6","author":"Liu","year":"2016","journal-title":"Sci Rep"},{"key":"10.1186\/s12576-024-00908-5_bb0160","article-title":"Short-chain fatty acid propionate alleviates Akt2 knockout-induced myocardial contractile dysfunction","author":"Li","year":"2012","journal-title":"J Diabetes Res"},{"key":"10.1186\/s12576-024-00908-5_bb0165","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/BF00381883","article-title":"Ovarian innervation develops before initiation of folliculogenesis in the rat","volume":"270","author":"Malamed","year":"1992","journal-title":"Cell Tissue Res"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0170","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1056\/NEJMcp1514916","article-title":"Polycystic ovary syndrome","volume":"375","author":"McCartney","year":"2016","journal-title":"N Engl J Med"},{"issue":"9","key":"10.1186\/s12576-024-00908-5_bb0175","doi-asserted-by":"crossref","first-page":"e9854","DOI":"10.15252\/emmm.201809854","article-title":"From molecular promise to preclinical results: HDAC inhibitors in the race for healthy aging drugs","volume":"11","author":"McIntyre","year":"2019","journal-title":"EMBO Mol Med"},{"key":"10.1186\/s12576-024-00908-5_bb0180","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.reprotox.2021.10.008","article-title":"Repression of HDAC5 by acetate restores hypothalamic-pituitary-ovarian function in type 2 diabetes mellitus","volume":"106","author":"Olaniyi","year":"2021","journal-title":"Reprod Toxicol"},{"issue":"7","key":"10.1186\/s12576-024-00908-5_bb0185","doi-asserted-by":"crossref","first-page":"e0272124","DOI":"10.1371\/journal.pone.0272124","article-title":"Short chain fatty acid, acetate restores ovarian function in experimentally induced PCOS rat model","volume":"17","author":"Olaniyi","year":"2022","journal-title":"PLoS ONE"},{"key":"10.1186\/s12576-024-00908-5_bb0190","doi-asserted-by":"crossref","first-page":"120560","DOI":"10.1016\/j.lfs.2022.120560","article-title":"Suppression of PCSK9\/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome","volume":"300","author":"Olaniyi","year":"2022","journal-title":"Life Sci"},{"key":"10.1186\/s12576-024-00908-5_bb0195","doi-asserted-by":"crossref","first-page":"115381","DOI":"10.1016\/j.taap.2020.115381","article-title":"Low dose spironolactone-mediated androgen-adiponectin modulation alleviates endocrine-metabolic disturbances in letrozole-induced PCOS","volume":"411","author":"Olaniyi","year":"2021","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1186\/s12576-024-00908-5_bb0200","doi-asserted-by":"crossref","first-page":"110226","DOI":"10.1016\/j.biopha.2020.110226","article-title":"Sodium acetate-mediated inhibition of histone deacetylase alleviates hepatic lipid dysregulation and its accompanied injury in streptozotocin-nicotinamide-induced diabetic rats","volume":"128","author":"Olaniyi","year":"2020","journal-title":"Biomed Pharmacother"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0205","doi-asserted-by":"crossref","first-page":"18967","DOI":"10.1038\/s41598-021-98605-5","article-title":"Acetate rescues defective brain-adipose metabolic network in obese Wistar rats by modulation of peroxisome proliferator-activated receptor-\u03b3","volume":"11","author":"Olaniyi","year":"2021","journal-title":"Sci Rep"},{"key":"10.1186\/s12576-024-00908-5_bb0210","doi-asserted-by":"crossref","first-page":"176243","DOI":"10.1016\/j.ejphar.2023.176243","article-title":"Cardiac energy depletion in a rat model of polycystic ovarian syndrome is reversed by acetate and associated with inhibitory effect of HDAC2\/mTOR","volume":"962","author":"Olaniyi","year":"2024","journal-title":"Eur J Pharmacol"},{"issue":"18","key":"10.1186\/s12576-024-00908-5_bb0215","doi-asserted-by":"crossref","first-page":"2709","DOI":"10.2174\/1381612822666160216151852","article-title":"Oxidative stress in polycystic ovary syndrome","volume":"22","author":"Papalou","year":"2016","journal-title":"Curr Pharm Des"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0220","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1080\/17446651.2021.1865152","article-title":"Tailoring treatment for PCOS phenotypes","volume":"16","author":"Papadakis","year":"2021","journal-title":"Expert Rev Endocrinol Metab"},{"key":"10.1186\/s12576-024-00908-5_bb0225","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/162021","article-title":"Evidence for the gut microbiota short-chain fatty acids as key pathophysiological molecules improving diabetes","author":"Puddu","year":"2014","journal-title":"Mediat Inflamm"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0230","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1177\/1933719113485294","article-title":"The role of TGF-\u03b2 in polycystic ovary syndrome","volume":"21","author":"Raja-Khan","year":"2014","journal-title":"Reprod Sci"},{"issue":"23","key":"10.1186\/s12576-024-00908-5_bb0235","doi-asserted-by":"crossref","first-page":"10952","DOI":"10.18632\/aging.102497","article-title":"Global, regional, and national prevalence and disability-adjusted life-years for infertility in 195 countries and territories, 1990\u20132017: results from a global burden of disease study, 2017","volume":"11","author":"Sun","year":"2019","journal-title":"Aging (Albany NY)"},{"issue":"4","key":"10.1186\/s12576-024-00908-5_bb0240","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1093\/biolre\/ioy242","article-title":"A high level of TGF-B1 promotes endometriosis development via cell migration, adhesiveness, colonization, and invasiveness","volume":"100","author":"Soni","year":"2019","journal-title":"Biol Reprod"},{"issue":"10","key":"10.1186\/s12576-024-00908-5_bb0245","doi-asserted-by":"crossref","first-page":"3592","DOI":"10.3390\/ijms21103592","article-title":"Mitochondrial function in modulating human granulosa cell steroidogenesis and female fertility","volume":"21","author":"Sreerangaraja","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"4","key":"10.1186\/s12576-024-00908-5_bb0250","first-page":"157","article-title":"Leptin and adiponectin: from energy and metabolic dysbalance to inflammation and autoimmunity","volume":"43","author":"Stofkova","year":"2009","journal-title":"Endocr Regul"},{"key":"10.1186\/s12576-024-00908-5_bb0255","unstructured":"Urooj Z, Zahida M, Kausar M, Shanza A, Jahan AH, Dabeeran Z (2019) Prevalence of PCOS with Associated Symptoms and Complications at Tertiary Care Hospital of Karachi."},{"issue":"12","key":"10.1186\/s12576-024-00908-5_bb0260","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1158\/1535-7163.MCT-18-0348","article-title":"Histone deacetylase inhibitors synergize with catalytic inhibitors of EZH2 to exhibit antitumor activity in small cell carcinoma of the ovary, hypercalcemic type","volume":"17","author":"Wang","year":"2018","journal-title":"Mol Cancer Ther"},{"issue":"2","key":"10.1186\/s12576-024-00908-5_bb0265","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1093\/biolre\/ioab078","article-title":"NAD+ deficiency and mitochondrial dysfunction in granulosa cells of women with polycystic ovary syndrome","volume":"105","author":"Wang","year":"2021","journal-title":"Biol Reprod"},{"key":"10.1186\/s12576-024-00908-5_bb0270","doi-asserted-by":"crossref","first-page":"103493","DOI":"10.1016\/j.mcn.2020.103493","article-title":"Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells","volume":"105","author":"Wenzel","year":"2020","journal-title":"Mol Cell Neurosci"},{"issue":"22","key":"10.1186\/s12576-024-00908-5_bb0275","doi-asserted-by":"crossref","first-page":"5787","DOI":"10.3390\/ijms20225787","article-title":"Inositols\u2019 importance in the improvement of the endocrine\u2013metabolic profile in PCOS","volume":"20","author":"Wojciechowska","year":"2019","journal-title":"Int J Mol Sci"},{"key":"10.1186\/s12576-024-00908-5_bb0280","first-page":"1894","article-title":"Brink M (2016) mTOR, cardiomyocytes and inflammation in cardiac hypertrophy","volume":"7","author":"Xu","year":"1863","journal-title":"Biochim Biophys Acta"},{"key":"10.1186\/s12576-024-00908-5_bb0285","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/9240569","article-title":"Association of insulin resistance and elevated androgen levels with polycystic ovarian syndrome (PCOS): a review of literature","author":"Xu","year":"2022","journal-title":"J Healthc Eng"},{"key":"10.1186\/s12576-024-00908-5_bb0290","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s40257-020-00565-5","article-title":"Metformin therapy for acne in patients with polycystic ovary syndrome: a systematic review and meta-analysis","volume":"22","author":"Yen","year":"2021","journal-title":"Am J Clin Dermatol"},{"issue":"12","key":"10.1186\/s12576-024-00908-5_bb0295","doi-asserted-by":"crossref","first-page":"3919","DOI":"10.18632\/aging.102024","article-title":"Mitofusin 2 plays a role in oocyte and follicle development, and is required to maintain ovarian follicular reserve during reproductive aging","volume":"11","author":"Zhang","year":"2019","journal-title":"Aging (Albany NY)"},{"issue":"1","key":"10.1186\/s12576-024-00908-5_bb0300","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12958-019-0509-4","article-title":"Polycystic ovary syndrome and mitochondrial dysfunction","volume":"17","author":"Zhang","year":"2019","journal-title":"Reprod Biol Endocrinol"},{"issue":"5","key":"10.1186\/s12576-024-00908-5_bb0305","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1177\/1933719116670265","article-title":"Leptin levels in women with polycystic ovary syndrome: a systematic review and a meta-analysis","volume":"24","author":"Zheng","year":"2017","journal-title":"Reprod Sci"},{"issue":"4","key":"10.1186\/s12576-024-00908-5_bb0310","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1111\/cns.12217","article-title":"Histone decacetylase inhibitors prevent mitochondrial fragmentation and elicit early neuroprotection against MPP+","volume":"20","author":"Zhu","year":"2014","journal-title":"CNS Neurosci Ther"}],"container-title":["The Journal of Physiological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12576-024-00908-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12576-024-00908-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1880654624001021?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1880654624001021?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12576-024-00908-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T00:25:36Z","timestamp":1762561536000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1880654624001021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":61,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"alternative-id":["S1880654624001021"],"URL":"https:\/\/doi.org\/10.1186\/s12576-024-00908-5","relation":{},"ISSN":["1880-6546"],"issn-type":[{"value":"1880-6546","type":"print"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acetate ameliorates ovarian mitochondrial dysfunction in letrozole-induced polycystic ovarian syndrome rat model by improving mitofusin-2","name":"articletitle","label":"Article Title"},{"value":"The Journal of Physiological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1186\/s12576-024-00908-5","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"22"}}