{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T01:43:27Z","timestamp":1772502207296,"version":"3.50.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T00:00:00Z","timestamp":1533859200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genet"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12863-018-0664-1","type":"journal-article","created":{"date-parts":[[2018,8,10]],"date-time":"2018-08-10T12:15:09Z","timestamp":1533903309000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["High resolution melting curve analysis enables rapid and reliable detection of G6PD variants in heterozygous females"],"prefix":"10.1186","volume":"19","author":[{"given":"Md Tarikul","family":"Islam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suprovath Kumar","family":"Sarker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shezote","family":"Talukder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Golam Sarower","family":"Bhuyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asifuzzaman","family":"Rahat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nafisa Nawal","family":"Islam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Mahmud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Amir","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. K. M.","family":"Muraduzzaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakia","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syeda Kashfi","family":"Qadri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammod","family":"Shahidullah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Abdul","family":"Mannan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarabon","family":"Tahura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manzoor","family":"Hussain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narayan","family":"Saha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahida","family":"Akhter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazmun","family":"Nahar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firoza","family":"Begum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahmina","family":"Shirin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharif","family":"Akhteruzzaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Saleheen","family":"Qadri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firdausi","family":"Qadri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2394-0447","authenticated-orcid":false,"given":"Kaiissar","family":"Mannoor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,8,10]]},"reference":[{"issue":"3","key":"664_CR1","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.bcmd.2008.12.005","volume":"42","author":"ET Nkhoma","year":"2009","unstructured":"Nkhoma ET, Poole C, Vannappagari V, Hall SA, Beutler E. The global prevalence of glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysis. Blood Cells Mol Dis. 2009;42(3):267\u201378.","journal-title":"Blood Cells Mol Dis"},{"key":"664_CR2","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.freeradbiomed.2013.11.022","volume":"67","author":"R Van Zwieten","year":"2014","unstructured":"Van Zwieten R, Verhoeven AJ, Roos D. Inborn defects in the antioxidant systems of human red blood cells. Free Radic Biol Med. 2014;67:377\u201386.","journal-title":"Free Radic Biol Med"},{"issue":"1","key":"664_CR3","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1182\/blood-2007-04-077412","volume":"111","author":"E Beutler","year":"2008","unstructured":"Beutler E. Glucose-6-phosphate dehydrogenase deficiency: a historical perspective. Blood. 2008;111(1):16\u201324.","journal-title":"Blood"},{"issue":"4","key":"664_CR4","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1155\/2003\/913679","volume":"14","author":"A Monga","year":"2003","unstructured":"Monga A, Makkar RP, Arora A, Mukhopadhyay S, Gupta AK. Case report: acute hepatitis E infection with co-existent Glucose-6-phosphate dehydrogenase deficiency. Can J Infect Dis Med. 2003;14(4):230\u20131.","journal-title":"Can J Infect Dis Med"},{"issue":"S1","key":"664_CR5","doi-asserted-by":"publisher","first-page":"S46","DOI":"10.1038\/jp.2008.216","volume":"29","author":"M Kaplan","year":"2009","unstructured":"Kaplan M, Hammerman C. The need for neonatal glucose-6-phosphate dehydrogenase screening: a global perspective. J Perinatol. 2009;29(S1):S46.","journal-title":"J Perinatol"},{"issue":"5","key":"664_CR6","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1136\/adc.85.5.411","volume":"85","author":"P Raupp","year":"2001","unstructured":"Raupp P, Hassan JA, Varughese M, Kristiansson B. Henna causes life threatening haemolysis in glucose-6-phosphate dehydrogenase deficiency. Arch Dis Child. 2001;85(5):411\u20132.","journal-title":"Arch Dis Child"},{"issue":"9","key":"664_CR7","first-page":"987","volume":"86","author":"M Oliver","year":"2001","unstructured":"Oliver M, Coton T, Badens C, Dehan C, Lena-Russo D, Moalic JL. Homozygous G6PD deficiency and propacetamol induced hemolysis. Haematologica. 2001;86(9):987\u20138.","journal-title":"Haematologica"},{"issue":"2","key":"664_CR8","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.hoc.2015.11.006","volume":"30","author":"L Luzzatto","year":"2016","unstructured":"Luzzatto L, Nannelli C, Notaro R. Glucose-6-phosphate dehydrogenase deficiency. Hematol Oncol Clin North Am. 2016;30(2):373\u201393.","journal-title":"Hematol Oncol Clin North Am"},{"issue":"4932","key":"664_CR9","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1038\/202606b0","volume":"202","author":"O T\u00f6nz","year":"1964","unstructured":"T\u00f6nz O, Rossi E. Morphological demonstration of two red cell populations in human females heterozygous for glucose-6-phosphate dehydrogenase deficiency. Nature. 1964;202(4932):606.","journal-title":"Nature"},{"issue":"3","key":"664_CR10","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1136\/jcp.2004.017426","volume":"58","author":"F Lim","year":"2005","unstructured":"Lim F, Vulliamy T, Abdalla S. An Ashkenazi Jewish woman presenting with favism. J Clin Pathol. 2005;58(3):317\u20139.","journal-title":"J Clin Pathol"},{"issue":"2","key":"664_CR11","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1111\/j.1365-2141.1983.tb02017.x","volume":"53","author":"T Meloni","year":"1983","unstructured":"Meloni T, Forteleoni G, Dore A, Cutillo S. Neonatal hyperbilirubinaemia in heterozygous giucose-6-phosphate dehydrogenase deficient females. Br J Haematol. 1983;53(2):241\u20136.","journal-title":"Br J Haematol"},{"issue":"2","key":"664_CR12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002224","volume":"14","author":"CS Chu","year":"2017","unstructured":"Chu CS, Bancone G, Moore KA, Win HH, Thitipanawan N, Po C, et al. Haemolysis in G6PD heterozygous females treated with primaquine for plasmodium vivax malaria: a nested cohort in a trial of radical curative regimens. PLoS Med. 2017;14(2):e1002224.","journal-title":"PLoS Med"},{"issue":"4","key":"664_CR13","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/j.jpeds.2008.10.049","volume":"154","author":"S Zangen","year":"2009","unstructured":"Zangen S, Kidron D, Gelbart T, Roy-Chowdhury N, Wang X, Kaplan M. Fatal kernicterus in a girl deficient in glucose-6-phosphate dehydrogenase: a paradigm of synergistic heterozygosity. J Pediatr. 2009;154(4):616\u20139.","journal-title":"J Pediatr"},{"issue":"7","key":"664_CR14","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1038\/sj.jp.7210769","volume":"22","author":"M Herschel","year":"2002","unstructured":"Herschel M, Ryan M, Gelbart T, Kaplan M. Hemolysis and hyperbilirubinemia in an African American neonate heterozygous for glucose-6-phosphate dehydrogenase deficiency. J Perinatol. 2002;22(7):577.","journal-title":"J Perinatol"},{"key":"664_CR15","doi-asserted-by":"crossref","unstructured":"Kaplan M, Hammerman C, editors. Glucose-6-phosphate dehydrogenase deficiency and severe neonatal hyperbilirubinemia: a complexity of interactions between genes and environment. Semin. Fetal Neonatal Med; 2010: Elsevier.","DOI":"10.1016\/j.siny.2009.10.007"},{"issue":"10","key":"664_CR16","first-page":"1086","volume":"61","author":"W-Y Au","year":"2006","unstructured":"Au W-Y, Lam V, Pang A, Lee W-M, Chan JL, Song Y-Q, et al. Glucose-6-phosphate dehydrogenase deficiency in female octogenarians, nanogenarians, and centenarians. The J. Gerontol. A biol. Sci. Med. Sci. 2006;61(10):1086\u20139.","journal-title":"Sci"},{"issue":"4","key":"664_CR17","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1542\/peds.96.4.734","volume":"96","author":"MG MacDonald","year":"1995","unstructured":"MacDonald MG. Hidden risks: early discharge and bilirubin toxicity due to glucose 6-phosphate dehydrogenase deficiency. Pediatrics. 1995;96(4):734\u20138.","journal-title":"Pediatrics"},{"issue":"2","key":"664_CR18","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1093\/tropej\/49.2.74","volume":"49","author":"AK Nair","year":"2003","unstructured":"Nair AK, Al Khusaiby SM. Kernicterus and G6PD deficiency\u2014a case series from Oman. J Trop Pediatr. 2003;49(2):74\u20137.","journal-title":"J Trop Pediatr"},{"issue":"11","key":"664_CR19","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1369\/jhc.2009.953828","volume":"57","author":"AL Peters","year":"2009","unstructured":"Peters AL, Noorden CJV. Glucose-6-phosphate dehydrogenase deficiency and malaria: cytochemical detection of heterozygous G6PD deficiency in women. J Histochem Cytochem. 2009;57(11):1003\u201311.","journal-title":"J Histochem Cytochem"},{"issue":"9","key":"664_CR20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007246","volume":"4","author":"MK Johnson","year":"2009","unstructured":"Johnson MK, Clark TD, Njama-Meya D, Rosenthal PJ, Parikh S. Impact of the method of G6PD deficiency assessment on genetic association studies of malaria susceptibility. PLoS One. 2009;4(9):e7246.","journal-title":"PLoS One"},{"key":"664_CR21","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/srep00299","volume":"2","author":"SS Shah","year":"2012","unstructured":"Shah SS, Diakite SA, Traore K, Diakite M, Kwiatkowski DP, Rockett KA, et al. A novel cytofluorometric assay for the detection and quantification of glucose-6-phosphate dehydrogenase deficiency. Sci Rep. 2012;2:299.","journal-title":"Sci Rep"},{"issue":"3","key":"664_CR22","doi-asserted-by":"publisher","first-page":"305","DOI":"10.2353\/jmoldx.2010.090104","volume":"12","author":"Y Jb","year":"2010","unstructured":"Jb Y, Hp X, Xiong C, Zr R, Gl T, Zeng F, et al. Rapid and reliable detection of glucose-6-phosphate dehydrogenase (G6PD) gene mutations in Han Chinese using high-resolution melting analysis. J Mol Diagn. 2010;12(3):305\u201311.","journal-title":"J Mol Diagn"},{"issue":"1","key":"664_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12863-017-0594-3","volume":"19","author":"MT Islam","year":"2018","unstructured":"Islam MT, Sarkar SK, Sultana N, Begum MN, Bhuyan GS, Talukder S, et al. High resolution melting curve analysis targeting the HBB gene mutational hot-spot offers a reliable screening approach for all common as well as most of the rare beta-globin gene mutations in Bangladesh. BMC Genet. 2018;19(1):1.","journal-title":"BMC Genet"},{"issue":"1","key":"664_CR24","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1186\/1756-0500-4-323","volume":"4","author":"C Bono","year":"2011","unstructured":"Bono C, Nuzzo D, Albeggiani G, Zizzo C, Francofonte D, Iemolo F, et al. Genetic screening of Fabry patients with EcoTILLING and HRM technology. BMC Res Notes. 2011;4(1):323.","journal-title":"BMC Res Notes"},{"issue":"1","key":"664_CR25","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/1471-2369-12-57","volume":"12","author":"S Bataille","year":"2011","unstructured":"Bataille S, Berland Y, Fontes M, Burtey S. High resolution melt analysis for mutation screening in PKD1 and PKD2. BMC Nephrol. 2011;12(1):57.","journal-title":"BMC Nephrol"},{"issue":"11","key":"664_CR26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0166977","volume":"11","author":"SK Sarker","year":"2016","unstructured":"Sarker SK, Islam MT, Eckhoff G, Hossain MA, Qadri SK, Muraduzzaman A, et al. Molecular analysis of Glucose-6-phosphate dehydrogenase gene mutations in Bangladeshi individuals. PLoS One. 2016;11(11):e0166977.","journal-title":"PLoS One"},{"issue":"3","key":"664_CR27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040066","volume":"4","author":"A Guindo","year":"2007","unstructured":"Guindo A, Fairhurst RM, Doumbo OK, Wellems TE, Diallo DA. X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria. PLoS Med. 2007;4(3):e66.","journal-title":"PLoS Med"},{"issue":"12","key":"664_CR28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004031","volume":"3","author":"CI Fanello","year":"2008","unstructured":"Fanello CI, Karema C, Avellino P, Bancone G, Uwimana A, Lee SJ, et al. High risk of severe anaemia after chlorproguanil-dapsone+ artesunate antimalarial treatment in patients with G6PD (A-) deficiency. PLoS One. 2008;3(12):e4031.","journal-title":"PLoS One"},{"issue":"1","key":"664_CR29","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1093\/tropej\/fml067","volume":"53","author":"N Muslu","year":"2006","unstructured":"Muslu N, Turhan AB, Eskandari G, Atici A, Ozturk OG, Kul S, et al. The frequency of UDP-glucuronosyltransferase 1A1 promoter region (TA) 7 polymorphism in newborns and it's relation with jaundice. J Trop Pediatr. 2006;53(1):64\u20138.","journal-title":"J Trop Pediatr"},{"issue":"1","key":"664_CR30","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1007\/s100380050100","volume":"44","author":"K Akaba","year":"1999","unstructured":"Akaba K, Kimura T, Sasaki A, Tanabe S, Wakabayashi T, Hiroi M, et al. Neonatal hyperbilirubinemia and a common mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene in Japanese. Hum Genet. 1999;44(1):22\u20135.","journal-title":"Hum Genet"},{"issue":"14","key":"664_CR31","doi-asserted-by":"publisher","first-page":"8170","DOI":"10.1073\/pnas.95.14.8170","volume":"95","author":"E Beutler","year":"1998","unstructured":"Beutler E, Gelbart T, Demina A. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? Proc Natl Acad Sci U S A. 1998;95(14):8170\u20134.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"664_CR32","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1203\/PDR.0b013e31815b8e7e","volume":"63","author":"M Kaplan","year":"2008","unstructured":"Kaplan M, Slusher T, Renbaum P, Essiet DF, Pam S, Levy-Lahad E, et al. n UDP-glucuronosyltransferase 1A1 promoter polymorphism in Nigerian neonates. Pediatr. Res. 2008;63(1):109.","journal-title":"Pediatr. Res"},{"issue":"1","key":"664_CR33","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1002\/iub.137","volume":"61","author":"A Minucci","year":"2009","unstructured":"Minucci A, Giardina B, Zuppi C, Capoluongo E. Glucose-6-phosphate dehydrogenase laboratory assay: how, when, and why? IUBMB Life. 2009;61(1):27\u201334.","journal-title":"IUBMB Life"},{"issue":"8","key":"664_CR34","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1182\/blood.V81.8.2150.2150","volume":"81","author":"D Chiu","year":"1993","unstructured":"Chiu D, Zuo L, Chao L, Chen E, Louie E, Lubin B, et al. Molecular characterization of glucose-6-phosphate dehydrogenase (G6PD) deficiency in patients of Chinese descent and identification of new base substitutions in the human G6PD gene. Blood. 1993;81(8):2150\u20134.","journal-title":"Blood"},{"issue":"4","key":"664_CR35","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/BF00273657","volume":"80","author":"C Du","year":"1988","unstructured":"Du C, Xu Y, Hua X, Wu Q, Liu L. Glucose-6-phosphate dehydrogenase variants and their frequency in Guangdong. China Hum Genet. 1988;80(4):385\u20138.","journal-title":"China Hum Genet"},{"issue":"12","key":"664_CR36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116063","volume":"9","author":"G Bancone","year":"2014","unstructured":"Bancone G, Chu CS, Somsakchaicharoen R, Chowwiwat N, Parker DM, Charunwatthana P, et al. Characterization of G6PD genotypes and phenotypes on the northwestern Thailand-Myanmar border. PLoS One. 2014;9(12):e116063.","journal-title":"PLoS One"},{"issue":"1","key":"664_CR37","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1186\/1475-2875-10-368","volume":"10","author":"P Phompradit","year":"2011","unstructured":"Phompradit P, Kuesap J, Chaijaroenkul W, Rueangweerayut R, Hongkaew Y, Yamnuan R, et al. Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand. Malar J. 2011;10(1):368.","journal-title":"Malar J"},{"issue":"5","key":"664_CR38","doi-asserted-by":"crossref","first-page":"516","DOI":"10.4103\/0971-5916.159499","volume":"141","author":"MB Mukherjee","year":"2015","unstructured":"Mukherjee MB, Colah RB, Martin S, Ghosh K. Glucose-6-phosphate dehydrogenase (G6PD) deficiency among tribal populations of India-country scenario. Indian J Med Res. 2015;141(5):516.","journal-title":"Indian J Med Res"},{"issue":"3","key":"664_CR39","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/S1079-9796(03)00018-4","volume":"30","author":"S Sukumar","year":"2003","unstructured":"Sukumar S, Mukherjee M, Colah R, Mohanty D. Molecular characterization of G6PD Insuli\u2014a novel 989 CGC\u2192 CAC (330 Arg\u2192 his) mutation in the Indian population. Blood Cells Mol Dis. 2003;30(3):246\u20137.","journal-title":"Blood Cells Mol Dis"},{"issue":"6","key":"664_CR40","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1111\/j.1751-553X.2011.01325.x","volume":"33","author":"B Moiz","year":"2011","unstructured":"Moiz B, Nasir A, Moatter T, Naqvi Z, Khurshid M. Molecular characterization of glucose-6-phosphate dehydrogenase deficiency in Pakistani population. Int J Lab Hematol. 2011;33(6):570\u20138.","journal-title":"Int J Lab Hematol"},{"issue":"1","key":"664_CR41","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1186\/1475-2875-12-230","volume":"12","author":"T Leslie","year":"2013","unstructured":"Leslie T, Moiz B, Mohammad N, Amanzai O, Ur Rasheed H, Jan S, et al. Prevalence and molecular basis of glucose-6-phosphate dehydrogenase deficiency in afghan populations: implications for treatment policy in the region. Malar J. 2013;12(1):230.","journal-title":"Malar J"},{"issue":"10","key":"664_CR42","doi-asserted-by":"publisher","first-page":"1748","DOI":"10.1373\/clinchem.2003.029751","volume":"50","author":"GH Reed","year":"2004","unstructured":"Reed GH, Wittwer CT. Sensitivity and specificity of single-nucleotide polymorphism scanning by high-resolution melting analysis. Clin Chem. 2004;50(10):1748\u201354.","journal-title":"Clin Chem"},{"issue":"6","key":"664_CR43","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1002\/humu.21019","volume":"30","author":"RH Vossen","year":"2009","unstructured":"Vossen RH, Aten E, Roos A, den Dunnen JT. High-resolution melting analysis (HRMA)\u2014more than just sequence variant screening. Hum Mutat. 2009;30(6):860\u20136.","journal-title":"Hum Mutat"},{"issue":"11","key":"664_CR44","doi-asserted-by":"publisher","first-page":"2316","DOI":"10.3390\/ijms18112316","volume":"18","author":"M S\u0142omka","year":"2017","unstructured":"S\u0142omka M, Sobalska-Kwapis M, Wachulec M, Bartosz G, Strapagiel D. High resolution melting (HRM) for high-throughput genotyping\u2014limitations and caveats in practical case studies. Int J Mol Sci. 2017;18(11):2316.","journal-title":"Int J Mol Sci"},{"issue":"1","key":"664_CR45","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1471-2156-10-5","volume":"10","author":"S Garritano","year":"2009","unstructured":"Garritano S, Gemignani F, Voegele C, Nguyen-Dumont T, Le Calvez-Kelm F, De Silva D, et al. Determining the effectiveness of high resolution melting analysis for SNP genotyping and mutation scanning at the TP53 locus. BMC Genet. 2009;10(1):5.","journal-title":"BMC Genet"}],"container-title":["BMC Genetics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12863-018-0664-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12863-018-0664-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12863-018-0664-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T08:42:46Z","timestamp":1751791366000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgenet.biomedcentral.com\/articles\/10.1186\/s12863-018-0664-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,10]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["664"],"URL":"https:\/\/doi.org\/10.1186\/s12863-018-0664-1","relation":{},"ISSN":["1471-2156"],"issn-type":[{"value":"1471-2156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,10]]},"assertion":[{"value":"24 April 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 July 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The Ethical approval for the study was taken from Bangladesh Medical Research Council (BMRC) of National Ethics Review Committee (NERC), Dhaka, Bangladesh. Prior to enrollment of the study participants, written informed consents were obtained from the parents or guardians of the study participants.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"58"}}