{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:14:43Z","timestamp":1792700083743,"version":"4.5.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation Project of China","doi-asserted-by":"crossref","award":["Grant No. 82060836"],"award-info":[{"award-number":["Grant No. 82060836"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation Project of China","doi-asserted-by":"crossref","award":["Grant No. 82060836"],"award-info":[{"award-number":["Grant No. 82060836"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation Project of China","doi-asserted-by":"crossref","award":["Grant No. 82060836"],"award-info":[{"award-number":["Grant No. 82060836"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation Project of China","doi-asserted-by":"crossref","award":["Grant No. 82060836"],"award-info":[{"award-number":["Grant No. 82060836"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation Project of China","doi-asserted-by":"crossref","award":["Grant No. 82060836"],"award-info":[{"award-number":["Grant No. 82060836"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation Project of China","doi-asserted-by":"crossref","award":["Grant No. 82060836"],"award-info":[{"award-number":["Grant No. 82060836"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation Project of China","doi-asserted-by":"crossref","award":["Grant No. 82060836"],"award-info":[{"award-number":["Grant No. 82060836"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genom Data"],"DOI":"10.1186\/s12863-024-01274-2","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T12:02:42Z","timestamp":1730203362000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Genetic overlap between inflammatory bowel disease and iridocyclitis: insights from a genome-wide association study in a European population"],"prefix":"10.1186","volume":"25","author":[{"given":"Wu","family":"Liao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghua","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leichang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengyun","family":"Zuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,29]]},"reference":[{"key":"1274_CR1","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1053\/j.gastro.2015.08.001","volume":"149","author":"DPB McGovern","year":"2015","unstructured":"McGovern DPB, Kugathasan S, Cho JH. Genetics of inflammatory bowel diseases. Gastroenterology. 2015;149:1163\u2013e11762. https:\/\/doi.org\/10.1053\/j.gastro.2015.08.001","journal-title":"Gastroenterology"},{"key":"1274_CR2","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1146\/annurev-immunol-032414-112151","volume":"34","author":"JM Peloquin","year":"2016","unstructured":"Peloquin JM, Goel G, Villablanca EJ, Xavier RJ. Mechanisms of pediatric inflammatory bowel disease. Annu Rev Immunol. 2016;34:31\u201364. https:\/\/doi.org\/10.1146\/annurev-immunol-032414-112151","journal-title":"Annu Rev Immunol"},{"key":"1274_CR3","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1038\/nrgastro.2015.150","volume":"12","author":"GG Kaplan","year":"2015","unstructured":"Kaplan GG. The global burden of IBD: from 2015 to 2025. Nat Rev Gastroenterol Hepatol. 2015;12:720\u20137. https:\/\/doi.org\/10.1038\/nrgastro.2015.150","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"1274_CR4","doi-asserted-by":"publisher","first-page":"1832","DOI":"10.1093\/ibd\/izaa359","volume":"27","author":"J Shah","year":"2021","unstructured":"Shah J, Shah A, Hassman L, Gutierrez A. Ocular manifestations of inflammatory bowel disease. Inflamm Bowel Dis. 2021;27:1832\u20138. https:\/\/doi.org\/10.1093\/ibd\/izaa359","journal-title":"Inflamm Bowel Dis"},{"key":"1274_CR5","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1093\/ecco-jcc\/jjv213","volume":"10","author":"M Harbord","year":"2016","unstructured":"Harbord M, Annese V, Vavricka SR, Allez M, Barreiro-de Acosta M, Boberg KM, Burisch J, De Vos M, De Vries A-M, Dick AD, et al. The first European evidence-based consensus on extra-intestinal manifestations in inflammatory bowel disease. J Crohn\u2019s Colitis. 2016;10:239\u201354. https:\/\/doi.org\/10.1093\/ecco-jcc\/jjv213","journal-title":"J Crohn\u2019s Colitis"},{"key":"1274_CR6","doi-asserted-by":"publisher","first-page":"e11","DOI":"10.1016\/j.jfo.2017.11.003","volume":"41","author":"J Gueudry","year":"2018","unstructured":"Gueudry J, Muraine M. Anterior uveitis. J Fran\u00e7ais d\u2019Ophtalmologie. 2018;41:e11\u201321. https:\/\/doi.org\/10.1016\/j.jfo.2017.11.003","journal-title":"J Fran\u00e7ais d\u2019Ophtalmologie"},{"key":"1274_CR7","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1097\/MPG.0000000000001455","volume":"65","author":"T Greuter","year":"2017","unstructured":"Greuter T, Bertoldo F, Rechner R, Straumann A, Biedermann L, Zeitz J, Misselwitz B, Scharl M, Rogler G, Safroneeva E, et al. Extraintestinal manifestations of pediatric inflammatory bowel disease: prevalence, presentation, and anti-TNF treatment. J Pediatr Gastroenterol Nutr. 2017;65:200\u20136. https:\/\/doi.org\/10.1097\/MPG.0000000000001455","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"1274_CR8","doi-asserted-by":"publisher","first-page":"2704","DOI":"10.1016\/j.cgh.2019.03.040","volume":"17","author":"J Burisch","year":"2019","unstructured":"Burisch J, Jess T, Egeberg A. Incidence of immune-mediated inflammatory diseases among patients with inflammatory bowel diseases in Denmark. Clin Gastroenterol Hepatol. 2019;17:2704\u2013e27123. https:\/\/doi.org\/10.1016\/j.cgh.2019.03.040","journal-title":"Clin Gastroenterol Hepatol"},{"key":"1274_CR9","doi-asserted-by":"publisher","first-page":"6137","DOI":"10.3748\/wjg.v23.i33.6137","volume":"23","author":"ML Halling","year":"2017","unstructured":"Halling ML, Kjeldsen J, Knudsen T, Nielsen J, Hansen LK. Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases. World J Gastroenterol. 2017;23:6137\u201346. https:\/\/doi.org\/10.3748\/wjg.v23.i33.6137","journal-title":"World J Gastroenterol"},{"key":"1274_CR10","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1056\/NEJM199101103240203","volume":"324","author":"M Orholm","year":"1991","unstructured":"Orholm M, Munkholm P, Langholz E, Nielsen OH, S\u00f8rensen TI, Binder V. Familial occurrence of inflammatory bowel disease. N Engl J Med. 1991;324:84\u20138. https:\/\/doi.org\/10.1056\/NEJM199101103240203","journal-title":"N Engl J Med"},{"key":"1274_CR11","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1136\/gut.29.7.990","volume":"29","author":"C Tysk","year":"1988","unstructured":"Tysk C, Lindberg E, J\u00e4rnerot G, Flod\u00e9rus-Myrhed B. Ulcerative colitis and Crohn\u2019s disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking. Gut. 1988;29:990\u20136. https:\/\/doi.org\/10.1136\/gut.29.7.990","journal-title":"Gut"},{"key":"1274_CR12","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/0002-9394(88)90051-7","volume":"105","author":"PJ Derhaag","year":"1988","unstructured":"Derhaag PJ, Linssen A, Broekema N, de Waal LP, Feltkamp TE. A familial study of the inheritance of HLA-B27-positive acute anterior uveitis. Am J Ophthalmol. 1988;105:603\u20136. https:\/\/doi.org\/10.1016\/0002-9394(88)90051-7","journal-title":"Am J Ophthalmol"},{"key":"1274_CR13","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1038\/ng.3406","volume":"47","author":"B Bulik-Sullivan","year":"2015","unstructured":"Bulik-Sullivan B, Finucane HK, Anttila V, Gusev A, Day FR, Loh P-R, ReproGen Consortium PG, Consortium, Genetic Consortium for Anorexia Nervosa of the Wellcome Trust Case Control Consortium 3, Duncan L, et al. An atlas of genetic correlations across human diseases and traits. Nat Genet. 2015;47:1236\u201341. https:\/\/doi.org\/10.1038\/ng.3406","journal-title":"Nat Genet"},{"key":"1274_CR14","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1016\/j.ajhg.2017.09.022","volume":"101","author":"H Shi","year":"2017","unstructured":"Shi H, Mancuso N, Spendlove S, Pasaniuc B. Local genetic correlation gives insights into the shared genetic architecture of complex traits. Am J Hum Genet. 2017;101:737\u201351. https:\/\/doi.org\/10.1016\/j.ajhg.2017.09.022","journal-title":"Am J Hum Genet"},{"key":"1274_CR15","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1007\/s00439-019-02060-2","volume":"139","author":"OB Smeland","year":"2020","unstructured":"Smeland OB, Frei O, Shadrin A, O\u2019Connell K, Fan C-C, Bahrami S, Holland D, Djurovic S, Thompson WK, Dale AM, et al. Discovery of shared genomic loci using the conditional false discovery rate approach. Hum Genet. 2020;139:85\u201394. https:\/\/doi.org\/10.1007\/s00439-019-02060-2","journal-title":"Hum Genet"},{"key":"1274_CR16","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1038\/s41586-022-05473-8","volume":"613","author":"MI Kurki","year":"2023","unstructured":"Kurki MI, Karjalainen J, Palta P, Sipil\u00e4 TP, Kristiansson K, Donner KM, Reeve MP, Laivuori H, Aavikko M, Kaunisto MA, et al. FinnGen provides genetic insights from a well-phenotyped isolated population. Nature. 2023;613:508\u201318. https:\/\/doi.org\/10.1038\/s41586-022-05473-8","journal-title":"Nature"},{"key":"1274_CR17","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1038\/ng.3211","volume":"47","author":"BK Bulik-Sullivan","year":"2015","unstructured":"Bulik-Sullivan BK, Loh P-R, Finucane HK, Ripke S, Yang J, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patterson N, Daly MJ, Price AL, Neale BM. LD score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet. 2015;47:291\u20135. https:\/\/doi.org\/10.1038\/ng.3211","journal-title":"Nat Genet"},{"key":"1274_CR18","doi-asserted-by":"publisher","first-page":"2417","DOI":"10.1038\/s41467-019-10310-0","volume":"10","author":"O Frei","year":"2019","unstructured":"Frei O, Holland D, Smeland OB, Shadrin AA, Fan CC, Maeland S, O\u2019Connell KS, Wang Y, Djurovic S, Thompson WK, et al. Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation. Nat Commun. 2019;10:2417. https:\/\/doi.org\/10.1038\/s41467-019-10310-0","journal-title":"Nat Commun"},{"key":"1274_CR19","doi-asserted-by":"publisher","first-page":"e1004926","DOI":"10.1371\/journal.pgen.1004926","volume":"11","author":"J Liley","year":"2015","unstructured":"Liley J, Wallace C. A pleiotropy-informed Bayesian false discovery rate adapted to a shared control design finds new disease associations from GWAS summary statistics. PLoS Genet. 2015;11:e1004926. https:\/\/doi.org\/10.1371\/journal.pgen.1004926","journal-title":"PLoS Genet"},{"key":"1274_CR20","doi-asserted-by":"publisher","first-page":"W60","DOI":"10.1093\/nar\/gky311","volume":"46","author":"M Franz","year":"2018","unstructured":"Franz M, Rodriguez H, Lopes C, Zuberi K, Montojo J, Bader GD, Morris Q. GeneMANIA update 2018. Nucleic Acids Res. 2018;46:W60\u20134. https:\/\/doi.org\/10.1093\/nar\/gky311","journal-title":"Nucleic Acids Res"},{"key":"1274_CR21","doi-asserted-by":"publisher","first-page":"1282","DOI":"10.3390\/jcm12041282","volume":"12","author":"Y Meng","year":"2023","unstructured":"Meng Y, Tan Z, Liu C, Dong W, Chen C. Association between inflammatory bowel disease and iridocyclitis: a Mendelian randomization study. J Clin Med. 2023;12:1282. https:\/\/doi.org\/10.3390\/jcm12041282","journal-title":"J Clin Med"},{"key":"1274_CR22","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1038\/nature11582","volume":"491","author":"L Jostins","year":"2012","unstructured":"Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012;491:119\u201324. https:\/\/doi.org\/10.1038\/nature11582","journal-title":"Nature"},{"key":"1274_CR23","doi-asserted-by":"publisher","unstructured":"Wakefield D, Clarke D, McCluskey P. Recent developments in HLA B27 anterior uveitis. Front Immunol. 2021;11. https:\/\/doi.org\/10.3389\/fimmu.2020.608134","DOI":"10.3389\/fimmu.2020.608134"},{"key":"1274_CR24","doi-asserted-by":"publisher","first-page":"e58","DOI":"10.1371\/journal.pgen.0030058","volume":"3","author":"C Libioulle","year":"2007","unstructured":"Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, et al. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet. 2007;3:e58. https:\/\/doi.org\/10.1371\/journal.pgen.0030058","journal-title":"PLoS Genet"},{"key":"1274_CR25","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1038\/s41435-022-00168-6","volume":"23","author":"X-F Huang","year":"2022","unstructured":"Huang X-F, Brown MA. Progress in the genetics of uveitis. Genes Immun. 2022;23:57\u201365. https:\/\/doi.org\/10.1038\/s41435-022-00168-6","journal-title":"Genes Immun"},{"key":"1274_CR26","doi-asserted-by":"publisher","unstructured":"Yan J, Hedl M, Abraham C. An inflammatory bowel disease\u2013risk variant in INAVA decreases pattern recognition receptor\u2013induced outcomes. J Clin Invest. 2017;127:2192\u2013205. https:\/\/doi.org\/10.1172\/JCI86282","DOI":"10.1172\/JCI86282"},{"key":"1274_CR27","doi-asserted-by":"publisher","first-page":"169","DOI":"10.16288\/j.yczz.20-392","volume":"43","author":"Z Yansen","year":"2021","unstructured":"Yansen Z, Lingang Z, Dali L, Mingyao L. Inflammatory bowel disease susceptible gene GPR35 promotes bowel inflammation in mice. Yi Chuan. 2021;43:169\u201381. https:\/\/doi.org\/10.16288\/j.yczz.20-392","journal-title":"Yi Chuan"},{"key":"1274_CR28","doi-asserted-by":"publisher","first-page":"717392","DOI":"10.3389\/fimmu.2021.717392","volume":"12","author":"B Kaya","year":"2021","unstructured":"Kaya B, Melhem H, Niess JH. GPR35 in intestinal diseases: from risk gene to function. Front Immunol. 2021;12:717392. https:\/\/doi.org\/10.3389\/fimmu.2021.717392","journal-title":"Front Immunol"},{"key":"1274_CR29","doi-asserted-by":"publisher","first-page":"175719","DOI":"10.1016\/j.ejphar.2023.175719","volume":"949","author":"W Otkur","year":"2023","unstructured":"Otkur W, Wang J, Hou T, Liu F, Yang R, Li Y, Xiang K, Pei S, Qi H, Lin H, et al. Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis. Eur J Pharmacol. 2023;949:175719. https:\/\/doi.org\/10.1016\/j.ejphar.2023.175719","journal-title":"Eur J Pharmacol"},{"key":"1274_CR30","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.3390\/cimb46030107","volume":"46","author":"L \u021aiburc\u0103","year":"2024","unstructured":"\u021aiburc\u0103 L, Zaha DC, Jurca MC, Severin E, Jurca A, Jurca AD. The role of aminopeptidase erap1 in human pathology-a review. Curr Issues Mol Biol. 2024;46:1651\u201367. https:\/\/doi.org\/10.3390\/cimb46030107","journal-title":"Curr Issues Mol Biol"},{"key":"1274_CR31","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1167\/iovs.61.6.3","volume":"61","author":"X-F Huang","year":"2020","unstructured":"Huang X-F, Li Z, De Guzman E, Robinson P, Gensler L, Ward MM, Rahbar MH, Lee M, Weisman MH, Macfarlane GJ, et al. Genomewide association study of acute anterior uveitis identifies new susceptibility loci. Invest Ophthalmol Vis Sci. 2020;61:3. https:\/\/doi.org\/10.1167\/iovs.61.6.3","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1274_CR32","doi-asserted-by":"publisher","first-page":"7300","DOI":"10.1038\/s41467-023-43036-1","volume":"14","author":"S Gelfman","year":"2023","unstructured":"Gelfman S, Moscati A, Huergo SM, Wang R, Rajagopal V, Parikshak N, Pounraja VK, Chen E, Leblanc M, Hazlewood R, et al. A large meta-analysis identifies genes associated with anterior uveitis. Nat Commun. 2023;14:7300. https:\/\/doi.org\/10.1038\/s41467-023-43036-1","journal-title":"Nat Commun"},{"key":"1274_CR33","doi-asserted-by":"publisher","first-page":"103512","DOI":"10.1016\/j.autrev.2023.103512","volume":"23","author":"L Ondrej\u010d\u00e1kov\u00e1","year":"2023","unstructured":"Ondrej\u010d\u00e1kov\u00e1 L, Gregov\u00e1 M, Bubov\u00e1 K, \u0160enolt L, Pavelka K. Serum biomarkers and their relationship to axial spondyloarthritis associated with inflammatory bowel diseases. Autoimmun Rev. 2023;23:103512. https:\/\/doi.org\/10.1016\/j.autrev.2023.103512","journal-title":"Autoimmun Rev"},{"key":"1274_CR34","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1177\/1753425917716527","volume":"23","author":"P Castro-Santos","year":"2017","unstructured":"Castro-Santos P, Moro-Garc\u00eda MA, Marcos-Fern\u00e1ndez R, Alonso-Arias R, D\u00edaz-Pe\u00f1a R. ERAP1 and HLA-C interaction in inflammatory bowel disease in the Spanish population. Innate Immun. 2017;23:476\u201381. https:\/\/doi.org\/10.1177\/1753425917716527","journal-title":"Innate Immun"},{"key":"1274_CR35","doi-asserted-by":"publisher","unstructured":"Mf N. Targeting immune cell circuits and trafficking in inflammatory bowel disease. Nat Immunol. 2019;20. https:\/\/doi.org\/10.1038\/s41590-019-0415-0","DOI":"10.1038\/s41590-019-0415-0"},{"key":"1274_CR36","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1146\/annurev-immunol-030409-101225","volume":"28","author":"A Kaser","year":"2010","unstructured":"Kaser A, Zeissig S, Blumberg RS. Inflammatory bowel disease. Annu Rev Immunol. 2010;28:573\u2013621. https:\/\/doi.org\/10.1146\/annurev-immunol-030409-101225","journal-title":"Annu Rev Immunol"},{"key":"1274_CR37","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3748\/wjg.v20.i1.91","volume":"20","author":"Y-Z Zhang","year":"2014","unstructured":"Zhang Y-Z, Li Y-Y. Inflammatory bowel disease: pathogenesis. World J Gastroenterol. 2014;20:91\u20139. https:\/\/doi.org\/10.3748\/wjg.v20.i1.91","journal-title":"World J Gastroenterol"},{"key":"1274_CR38","doi-asserted-by":"publisher","first-page":"3073","DOI":"10.1172\/JCI42440","volume":"120","author":"RR Caspi","year":"2010","unstructured":"Caspi RR. A look at autoimmunity and inflammation in the eye. J Clin Invest. 2010;120:3073\u201383. https:\/\/doi.org\/10.1172\/JCI42440","journal-title":"J Clin Invest"},{"key":"1274_CR39","doi-asserted-by":"publisher","first-page":"3338","DOI":"10.4049\/jimmunol.1004019","volume":"187","author":"H-M Oh","year":"2011","unstructured":"Oh H-M, Yu C-R, Lee Y, Chan C-C, Maminishkis A, Egwuagu CE. Autoreactive memory CD4\u2009+\u2009T lymphocytes that mediate chronic uveitis reside in the bone marrow through STAT3-dependent mechanisms. J Immunol. 2011;187:3338\u201346. https:\/\/doi.org\/10.4049\/jimmunol.1004019","journal-title":"J Immunol"},{"key":"1274_CR40","doi-asserted-by":"publisher","unstructured":"Rr RH. Microbiome and autoimmune uveitis. Front Immunol. 2019;10. https:\/\/doi.org\/10.3389\/fimmu.2019.00232","DOI":"10.3389\/fimmu.2019.00232"},{"key":"1274_CR41","doi-asserted-by":"publisher","first-page":"108970","DOI":"10.1016\/j.exer.2022.108970","volume":"217","author":"X Qin","year":"2022","unstructured":"Qin X, Zou H, Niu C. The STING pathway: an uncharacterized angle beneath the gut-retina axis. Exp Eye Res. 2022;217:108970. https:\/\/doi.org\/10.1016\/j.exer.2022.108970","journal-title":"Exp Eye Res"},{"key":"1274_CR42","doi-asserted-by":"publisher","first-page":"E4472","DOI":"10.1073\/pnas.1702302114","volume":"114","author":"S Rowan","year":"2017","unstructured":"Rowan S, Jiang S, Korem T, Szymanski J, Chang M-L, Szelog J, Cassalman C, Dasuri K, McGuire C, Nagai R, et al. Involvement of a gut-retina axis in protection against dietary glycemia-induced age-related macular degeneration. Proc Natl Acad Sci U S A. 2017;114:E4472\u201381. https:\/\/doi.org\/10.1073\/pnas.1702302114","journal-title":"Proc Natl Acad Sci U S A"},{"key":"1274_CR43","doi-asserted-by":"publisher","first-page":"8443","DOI":"10.3390\/ijms21228443","volume":"21","author":"J Moon","year":"2020","unstructured":"Moon J, Yoon CH, Choi SH, Kim MK. Can gut microbiota affect dry eye syndrome? Int J Mol Sci. 2020;21:8443. https:\/\/doi.org\/10.3390\/ijms21228443","journal-title":"Int J Mol Sci"}],"container-title":["BMC Genomic Data"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12863-024-01274-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12863-024-01274-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12863-024-01274-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T13:26:38Z","timestamp":1730294798000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgenet.biomedcentral.com\/articles\/10.1186\/s12863-024-01274-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,29]]},"references-count":43,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["1274"],"URL":"https:\/\/doi.org\/10.1186\/s12863-024-01274-2","relation":{},"ISSN":["2730-6844"],"issn-type":[{"value":"2730-6844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,29]]},"assertion":[{"value":"12 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 October 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable. The data used for analysis were obtained from published studies and public databases. The GWAS database is a database of publicly available datasets, where each study has been approved by local institutional review boards and ethics committees.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"92"}}