{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:12:53Z","timestamp":1790435573855,"version":"4.1.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"Next-generation BioGreen21 Program SSAC, Rural Development Administration, Republic of Korea","award":["PJ011379"],"award-info":[{"award-number":["PJ011379"]}]},{"name":"Louisiana Biomedical Research Collaborative Program award"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genomics"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1186\/s12864-016-3233-x","type":"journal-article","created":{"date-parts":[[2016,11,14]],"date-time":"2016-11-14T13:12:39Z","timestamp":1479129159000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["A novel phase variant of the cholera pathogen shows stress-adaptive cryptic transcriptomic signatures"],"prefix":"10.1186","volume":"17","author":[{"given":"Bliss","family":"Lambert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maheshi","family":"Dassanayake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Ha","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shana B.","family":"Garrett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Yeol","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregg S.","family":"Pettis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,11,14]]},"reference":[{"key":"3233_CR1","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1128\/MMBR.62.4.1301-1314.1998","volume":"62","author":"SM Faruque","year":"1998","unstructured":"Faruque SM, Albert MJ, Mekalanos JJ. Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae. Microbiol Mol Biol Rev. 1998;62:1301\u201314.","journal-title":"Microbiol Mol Biol Rev"},{"key":"3233_CR2","doi-asserted-by":"crossref","first-page":"5773","DOI":"10.1128\/AEM.68.11.5773-5778.2002","volume":"68","author":"A Ali","year":"2002","unstructured":"Ali A, Rashid MH, Karaolis DK. High-frequency rugose exopolysaccharide production by Vibrio cholerae. Appl Environ Microbiol. 2002;68:5773\u20138.","journal-title":"Appl Environ Microbiol"},{"key":"3233_CR3","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1046\/j.1365-2958.1999.01624.x","volume":"34","author":"PI Watnick","year":"1999","unstructured":"Watnick PI, Kolter R. Steps in the development of a Vibrio cholerae El Tor biofilm. Mol Microbiol. 1999;34:586\u201395.","journal-title":"Mol Microbiol"},{"key":"3233_CR4","doi-asserted-by":"crossref","first-page":"4028","DOI":"10.1073\/pnas.96.7.4028","volume":"96","author":"FH Yildiz","year":"1999","unstructured":"Yildiz FH, Schoolnik GK. Vibrio cholerae O1 El Tor: identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formation. Proc Natl Acad Sci U S A. 1999;96:4028\u201333.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3233_CR5","doi-asserted-by":"crossref","first-page":"e86751","DOI":"10.1371\/journal.pone.0086751","volume":"9","author":"F Yildiz","year":"2014","unstructured":"Yildiz F, Fong J, Sadovskaya I, Grard T, Vinogradov E. Structural characterization of the extracellular polysaccharide from Vibrio cholerae O1 El-Tor. PLoS One. 2014;9:e86751.","journal-title":"PLoS One"},{"key":"3233_CR6","doi-asserted-by":"crossref","first-page":"3648","DOI":"10.1128\/AEM.64.10.3648-3655.1998","volume":"64","author":"SN Wai","year":"1998","unstructured":"Wai SN, Mizunoe Y, Takade A, Kawabata SI, Yoshida SI. Vibrio cholerae O1 strain TSI-4 produces the exopolysaccharide materials that determine colony morphology, stress resistance, and biofilm formation. Appl Environ Microbiol. 1998;64:3648\u201355.","journal-title":"Appl Environ Microbiol"},{"key":"3233_CR7","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S1534-5807(03)00295-8","volume":"5","author":"J Zhu","year":"2003","unstructured":"Zhu J, Mekalanos JJ. Quorum sensing-dependent biofilms enhance colonization in Vibrio cholerae. Dev Cell. 2003;5:647\u201356.","journal-title":"Dev Cell"},{"key":"3233_CR8","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1128\/JB.188.3.1049-1059.2006","volume":"188","author":"JC Fong","year":"2006","unstructured":"Fong JC, Karplus K, Schoolnik GK, Yildiz FH. Identification and characterization of RbmA, a novel protein required for the development of rugose colony morphology and biofilm structure in Vibrio cholerae. J Bacteriol. 2006;188:1049\u201359.","journal-title":"J Bacteriol"},{"key":"3233_CR9","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1016\/0140-6736(92)92289-R","volume":"340","author":"EW Rice","year":"1992","unstructured":"Rice EW, Johnson CJ, Clark RM, Fox KR, Reasoner DJ, Dunnigan ME, et al. Chlorine and survival of \u201crugose\u201d Vibrio cholerae. Lancet. 1992;340:740.","journal-title":"Lancet"},{"key":"3233_CR10","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1093\/infdis\/174.6.1364","volume":"174","author":"JG Morris Jr","year":"1996","unstructured":"Morris Jr JG, Sztein MB, Rice EW, Nataro JP, Losonsky GA, Panigrahi P, et al. Vibrio cholerae O1 can assume a chlorine-resistant rugose survival form that is virulent for humans. J Infect Dis. 1996;174:1364\u20138.","journal-title":"J Infect Dis"},{"key":"3233_CR11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/path.1700460102","volume":"46","author":"PB White","year":"1938","unstructured":"White PB. The rugose variant of vibrios. J Pathol Bacteriol. 1938;46:1\u20136.","journal-title":"J Pathol Bacteriol"},{"key":"3233_CR12","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0378-1097(03)00879-6","volume":"230","author":"MH Rashid","year":"2004","unstructured":"Rashid MH, Rajanna C, Zhang D, Pasquale V, Magder LS, Ali A, et al. Role of exopolysaccharide, the rugose phenotype and VpsR in the pathogenesis of epidemic Vibrio cholerae. FEMS Microbiol Lett. 2004;230:105\u201313.","journal-title":"FEMS Microbiol Lett"},{"key":"3233_CR13","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/35020000","volume":"406","author":"JF Heidelberg","year":"2000","unstructured":"Heidelberg JF, Eisen JA, Nelson WC, Clayton RA, Gwinn ML, Dodson RJ, et al. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature. 2000;406:477\u201383.","journal-title":"Nature"},{"key":"3233_CR14","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1099\/mic.0.040196-0","volume":"156","author":"JCN Fong","year":"2010","unstructured":"Fong JCN, Syed KA, Klose KE, Yildiz FH. Role of Vibrio polysaccharide (vps) genes in VPS production, biofilm formation and Vibrio cholerae pathogenesis. Microbiology. 2010;156:2757\u201369.","journal-title":"Microbiology"},{"key":"3233_CR15","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1128\/JB.01569-06","volume":"189","author":"JCN Fong","year":"2007","unstructured":"Fong JCN, Yildiz FH. The rbmBCDEF gene cluster modulates development of rugose colony morphology and biofilm formation in Vibrio cholerae. J Bacteriol. 2007;189:2319\u201330.","journal-title":"J Bacteriol"},{"key":"3233_CR16","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1128\/JB.183.5.1716-1726.2001","volume":"183","author":"FH Yildiz","year":"2001","unstructured":"Yildiz FH, Dolganov NA, Schoolnik GK. VpsR, a Member of the response regulators of the two-component regulatory systems, is required for expression of vps biosynthesis genes and EPS(ETr)-associated phenotypes in Vibrio cholerae O1 El Tor. J Bacteriol. 2001;183:1716\u201326.","journal-title":"J Bacteriol"},{"key":"3233_CR17","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1128\/JB.186.5.1574-1578.2004","volume":"186","author":"C Casper-Lindley","year":"2004","unstructured":"Casper-Lindley C, Yildiz FH. VpsT is a transcriptional regulator required for expression of vps biosynthesis genes and the development of rugose colonial morphology in Vibrio cholerae O1 El Tor. J Bacteriol. 2004;186:1574\u20138.","journal-title":"J Bacteriol"},{"key":"3233_CR18","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1111\/j.1365-2958.2004.04155.x","volume":"53","author":"AD Tischler","year":"2004","unstructured":"Tischler AD, Camilli A. Cyclic diguanylate (c-di-GMP) regulates Vibrio cholerae biofilm formation. Mol Microbiol. 2004;53:857\u201369.","journal-title":"Mol Microbiol"},{"key":"3233_CR19","doi-asserted-by":"crossref","first-page":"5873","DOI":"10.1128\/IAI.73.9.5873-5882.2005","volume":"73","author":"AD Tischler","year":"2005","unstructured":"Tischler AD, Camilli A. Cyclic diguanylate regulates Vibrio cholerae virulence gene expression. Infect Immun. 2005;73:5873\u201382.","journal-title":"Infect Immun"},{"key":"3233_CR20","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1046\/j.1365-2958.2003.03688.x","volume":"50","author":"BK Hammer","year":"2003","unstructured":"Hammer BK, Bassler BL. Quorum sensing controls biofilm formation in Vibrio cholerae. Mol Microbiol. 2003;50:101\u20134.","journal-title":"Mol Microbiol"},{"key":"3233_CR21","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/j.1365-2958.2004.04154.x","volume":"53","author":"FH Yildiz","year":"2004","unstructured":"Yildiz FH, Liu XS, Heydorn A, Schoolnik GK. Molecular analysis of rugosity in a Vibrio cholerae O1 El Tor phase variant. Mol Microbiol. 2004;53:497\u2013515.","journal-title":"Mol Microbiol"},{"key":"3233_CR22","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1128\/JB.01756-07","volume":"190","author":"CM Waters","year":"2008","unstructured":"Waters CM, Lu W, Rabinowitz JD, Bassler BL. Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT. J Bacteriol. 2008;190:2527\u201336.","journal-title":"J Bacteriol"},{"key":"3233_CR23","doi-asserted-by":"crossref","first-page":"3129","DOI":"10.1073\/pnas.052694299","volume":"99","author":"J Zhu","year":"2002","unstructured":"Zhu J, Miller MB, Vance RE, Dziejman M, Bassler BL, Mekalanos JJ. Quorum-sensing regulators control virulence gene expression in Vibrio cholerae. Proc Natl Acad Sci U S A. 2002;99:3129\u201334.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3233_CR24","doi-asserted-by":"crossref","first-page":"11145","DOI":"10.1073\/pnas.0703860104","volume":"104","author":"BK Hammer","year":"2007","unstructured":"Hammer BK, Bassler BL. Regulatory small RNAs circumvent the conventional quorum sensing pathway in pandemic Vibrio cholerae. Proc Natl Acad Sci U S A. 2007;104:11145\u20139.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3233_CR25","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.cell.2012.01.053","volume":"149","author":"BW Davies","year":"2012","unstructured":"Davies BW, Bogard RW, Young TS, Mekalanos JJ. Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for V. cholerae virulence. Cell. 2012;149:358\u201370.","journal-title":"Cell"},{"key":"3233_CR26","doi-asserted-by":"crossref","first-page":"7766","DOI":"10.1093\/nar\/gks567","volume":"40","author":"TG Dong","year":"2012","unstructured":"Dong TG, Mekalanos JJ. Characterization of the RpoN regulon reveals differential regulation of T6SS and new flagellar operons in Vibrio cholerae O37 strain V52. Nucleic Acids Res. 2012;40:7766\u201375.","journal-title":"Nucleic Acids Res"},{"key":"3233_CR27","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1126\/science.1260064","volume":"347","author":"S Borgeaud","year":"2015","unstructured":"Borgeaud S, Metzger LC, Scrignari T, Blokesch M. The type VI secretion system of Vibrio cholerae fosters horizontal gene transfer. Science. 2015;347:63\u20137.","journal-title":"Science"},{"key":"3233_CR28","doi-asserted-by":"crossref","first-page":"E766","DOI":"10.1073\/pnas.1500203112","volume":"112","author":"K Papenfort","year":"2015","unstructured":"Papenfort K, F\u00f6rstner KU, Cong J-P, Sharma CM, Bassler BL. Differential RNA-seq of Vibrio cholerae identifies the VqmR small RNA as a regulator of biofilm formation. Proc Natl Acad Sci U S A. 2015;112:E766\u201375.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3233_CR29","doi-asserted-by":"crossref","first-page":"R106","DOI":"10.1186\/gb-2010-11-10-r106","volume":"11","author":"S Anders","year":"2010","unstructured":"Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol. 2010;11:R106.","journal-title":"Genome Biol"},{"key":"3233_CR30","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","volume":"57","author":"Y Benjamini","year":"1995","unstructured":"Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B. 1995;57:289\u2013300.","journal-title":"J R Statist Soc B"},{"key":"3233_CR31","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1128\/MMBR.49.3.232-269.1985","volume":"49","author":"P Postma","year":"1985","unstructured":"Postma P, Lengeler J. Phosphoenolpyruvate: carbohydrate phosphotransferase system of bacteria. Microbiol Rev. 1985;49:232.","journal-title":"Microbiol Rev"},{"key":"3233_CR32","doi-asserted-by":"crossref","first-page":"3055","DOI":"10.1128\/JB.00213-10","volume":"192","author":"L Houot","year":"2010","unstructured":"Houot L, Chang S, Pickering BS, Absalon C, Watnick PI. The phosphoenolpyruvate phosphotransferase system regulates Vibrio cholerae biofilm formation through multiple independent pathways. J Bacteriol. 2010;192:3055\u201367.","journal-title":"J Bacteriol"},{"key":"3233_CR33","doi-asserted-by":"crossref","first-page":"4675","DOI":"10.1128\/AEM.01184-13","volume":"79","author":"P Ymele-Leki","year":"2013","unstructured":"Ymele-Leki P, Houot L, Watnick PI. Mannitol and the mannitol-specific enzyme IIB subunit activate Vibrio cholerae biofilm formation. Appl Environ Microbiol. 2013;79:4675\u201383.","journal-title":"Appl Environ Microbiol"},{"key":"3233_CR34","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1128\/JCM.43.3.1426-1429.2005","volume":"43","author":"A Ali","year":"2005","unstructured":"Ali A, Morris Jr JG, Johnson JA. Sugars inhibit expression of the rugose phenotype of Vibrio cholerae. J Clin Microbiol. 2005;43:1426\u20139.","journal-title":"J Clin Microbiol"},{"key":"3233_CR35","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/nbt.1754","volume":"29","author":"JT Robinson","year":"2011","unstructured":"Robinson JT, Thorvaldsd\u00f3ttir H, Winckler W, Guttman M, Lander ES, Getz G, et al. Integrative genomics viewer. Nat Biotechnol. 2011;29:24\u20136.","journal-title":"Nat Biotechnol"},{"key":"3233_CR36","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1128\/JB.00981-06","volume":"189","author":"S Beyhan","year":"2007","unstructured":"Beyhan S, Bilecen K, Salama SR, Casper-Lindley C, Yildiz FH. Regulation of rugosity and biofilm formation in Vibrio cholerae: comparison of VpsT and VpsR regulons and epistasis analysis of vpsT, vpsR, and hapR. J Bacteriol. 2007;189:388\u2013402.","journal-title":"J Bacteriol"},{"key":"3233_CR37","doi-asserted-by":"crossref","first-page":"e101280","DOI":"10.1371\/journal.pone.0101280","volume":"9","author":"T Song","year":"2014","unstructured":"Song T, Sabharwal D, Gurung JM, Cheng AT, Sj\u00f6str\u00f6m AE, Yildiz FH, et al. Vibrio cholerae utilizes direct sRNA regulation in expression of a biofilm matrix protein. PLoS One. 2014;9:e101280.","journal-title":"PLoS One"},{"key":"3233_CR38","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1128\/MMBR.69.1.12-50.2005","volume":"69","author":"AJ Wolfe","year":"2005","unstructured":"Wolfe AJ. The acetate switch. Microbiol Mol Biol Rev. 2005;69:12\u201350.","journal-title":"Microbiol Mol Biol Rev"},{"key":"3233_CR39","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.chom.2014.10.006","volume":"16","author":"S Hang","year":"2014","unstructured":"Hang S, Purdy AE, Robins WP, Wang Z, Mandal M, Chang S, et al. The acetate switch of an intestinal pathogen disrupts host insulin signaling and lipid metabolism. Cell Host Microbe. 2014;16:592\u2013604.","journal-title":"Cell Host Microbe"},{"key":"3233_CR40","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.resmic.2008.10.005","volume":"160","author":"K Marrero","year":"2009","unstructured":"Marrero K, S\u00e1nchez A, Rodr\u00edguez-Ulloa A, Gonz\u00e1lez LJ, Castellanos-Serra L, Paz-Lago D, et al. Anaerobic growth promotes synthesis of colonization factors encoded at the Vibrio pathogenicity island in Vibrio cholerae El Tor. Res Microbiol. 2009;160:48\u201356.","journal-title":"Res Microbiol"},{"key":"3233_CR41","doi-asserted-by":"crossref","first-page":"6038","DOI":"10.1128\/jb.175.18.6038-6040.1993","volume":"175","author":"H Suzuki","year":"1993","unstructured":"Suzuki H, Hashimoto W, Kumagai H. Escherichia coli K-12 can utilize an exogenous gamma-glutamyl peptide as an amino acid source, for which gamma-glutamyltranspeptidase is essential. J Bacteriol. 1993;175:6038\u201340.","journal-title":"J Bacteriol"},{"key":"3233_CR42","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.micpath.2007.05.007","volume":"43","author":"IHA Barnes","year":"2007","unstructured":"Barnes IHA, Bagnall MC, Browning DD, Thompson SA, Manning G, Newell DG. \u03b3-Glutamyl transpeptidase has a role in the persistent colonization of the avian gut by Campylobacter jejuni. Microb Pathog. 2007;43:198\u2013207.","journal-title":"Microb Pathog"},{"key":"3233_CR43","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1046\/j.1365-2958.1999.01271.x","volume":"31","author":"C Chevalier","year":"1999","unstructured":"Chevalier C, Thiberge JM, Ferrero RL, Labigne A. Essential role of Helicobacter pylori gamma-glutamyltranspeptidase for the colonization of the gastric mucosa of mice. Mol Microbiol. 1999;31:1359\u201372.","journal-title":"Mol Microbiol"},{"key":"3233_CR44","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1757-4749-6-20","volume":"6","author":"P Floch","year":"2014","unstructured":"Floch P, Pey V, Castroviejo M, Dupuy JW, Bonneu M, de la Guardia AH, et al. Role of Campylobacter jejuni gamma-glutamyl transpeptidase on epithelial cell apoptosis and lymphocyte proliferation. Gut Pathog. 2014;6:20.","journal-title":"Gut Pathog"},{"key":"3233_CR45","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0923-2508(01)01196-2","volume":"152","author":"FJ Detmers","year":"2001","unstructured":"Detmers FJ, Lanfermeijer FC, Poolman B. Peptides and ATP binding cassette peptide transporters. Res Microbiol. 2001;152:245\u201358.","journal-title":"Res Microbiol"},{"key":"3233_CR46","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.femsle.2004.09.007","volume":"240","author":"EM Lee","year":"2004","unstructured":"Lee EM, Ahn SH, Park JH, Lee JH, Ahn SC, Kong IS. Identification of oligopeptide permease (opp) gene cluster in Vibrio fluvialis and characterization of biofilm production by oppA knockout mutation. FEMS Microbiol Lett. 2004;240:21\u201330.","journal-title":"FEMS Microbiol Lett"},{"key":"3233_CR47","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1128\/JB.187.7.2519-2525.2005","volume":"187","author":"BL Grau","year":"2005","unstructured":"Grau BL, Henk MC, Pettis GS. High-frequency phase variation of Vibrio vulnificus 1003: isolation and characterization of a rugose phenotypic variant. J Bacteriol. 2005;187:2519\u201325.","journal-title":"J Bacteriol"},{"key":"3233_CR48","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1462-2920.2010.02369.x","volume":"13","author":"KL Garrison-Schilling","year":"2011","unstructured":"Garrison-Schilling KL, Grau BL, McCarter KS, Olivier BJ, Comeaux NE, Pettis GS. Calcium promotes exopolysaccharide phase variation and biofilm formation of the resulting phase variants in the human pathogen Vibrio vulnificus. Environ Microbiol. 2011;13:643\u201354.","journal-title":"Environ Microbiol"},{"key":"3233_CR49","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1128\/IAI.01289-07","volume":"76","author":"BL Grau","year":"2008","unstructured":"Grau BL, Henk MC, Garrison KL, Olivier BJ, Schulz RM, O'Reilly KL, et al. Further characterization of Vibrio vulnificus rugose variants and identification of a capsular and rugose exopolysaccharide gene cluster. Infect Immun. 2008;76:1485\u201397.","journal-title":"Infect Immun"},{"key":"3233_CR50","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.1923","volume":"9","author":"B Langmead","year":"2012","unstructured":"Langmead B, Salzberg SL. Fast gapped-read alignment with Bowtie 2. Nat Methods. 2012;9:357\u20139.","journal-title":"Nat Methods"},{"key":"3233_CR51","doi-asserted-by":"crossref","first-page":"4082","DOI":"10.1128\/JB.01540-08","volume":"191","author":"NJ Shikuma","year":"2009","unstructured":"Shikuma NJ, Yildiz FH. Identification and characterization of OscR, a transcriptional regulator involved in osmolarity adaptation in Vibrio cholerae. J Bacteriol. 2009;191:4082\u201396.","journal-title":"J Bacteriol"},{"key":"3233_CR52","unstructured":"Warnes GR, Bolker B, Bonebakker L, Gentleman R, Huber W, Liaw A et al. gplots: Various R programming tools for plotting data. R package version 2.12. 1. [ http:\/\/CRAN.R-project.org\/package=gplots ]."},{"key":"3233_CR53","first-page":"1","volume":"25","author":"S L\u00ea","year":"2008","unstructured":"L\u00ea S, Josse J, Husson F. FactoMineR: An R Package for Multivariate Analysis. J Stat Softw. 2008;25:1\u201318.","journal-title":"J Stat Softw"}],"container-title":["BMC Genomics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-016-3233-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T15:35:30Z","timestamp":1718897730000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcgenomics.biomedcentral.com\/articles\/10.1186\/s12864-016-3233-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,14]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["3233"],"URL":"https:\/\/doi.org\/10.1186\/s12864-016-3233-x","relation":{},"ISSN":["1471-2164"],"issn-type":[{"value":"1471-2164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,14]]},"article-number":"914"}}