{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T23:06:37Z","timestamp":1784934397226,"version":"3.55.0"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T00:00:00Z","timestamp":1523318400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","award":["233778"],"award-info":[{"award-number":["233778"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genomics"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12864-018-4591-3","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T10:30:58Z","timestamp":1524133858000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["MicroRNA expression profiles of bovine monocyte-derived macrophages infected in vitro with two strains of Streptococcus agalactiae"],"prefix":"10.1186","volume":"19","author":[{"given":"Anna Monika","family":"Lewandowska-Sabat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silje Furre","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trygve Roger","family":"Solberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olav","family":"\u00d8ster\u00e5s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f8rg","family":"Heringstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preben","family":"Boysen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid","family":"Olsaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,4,10]]},"reference":[{"issue":"3","key":"4591_CR1","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1002\/jcp.21639","volume":"218","author":"Y Bi","year":"2009","unstructured":"Bi Y, Liu G, Yang R. MicroRNAs: novel regulators during the immune response. J Cell Physiol. 2009;218(3):467\u201372.","journal-title":"J Cell Physiol"},{"issue":"4","key":"4591_CR2","doi-asserted-by":"publisher","first-page":"538","DOI":"10.3390\/ijms17040538","volume":"17","author":"TB Flor","year":"2016","unstructured":"Flor TB, Blom B. Pathogens use and abuse MicroRNAs to deceive the immune system. Int J Mol Sci. 2016;17(4):538.","journal-title":"Int J Mol Sci"},{"issue":"18","key":"4591_CR3","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1056\/NEJMoa1209026","volume":"368","author":"HL Janssen","year":"2013","unstructured":"Janssen HL, Reesink HW, Lawitz EJ, Zeuzem S, Rodriguez-Torres M, Patel K, et al. Treatment of HCV infection by targeting microRNA. N Engl J Med. 2013;368(18):1685\u201394.","journal-title":"N Engl J Med"},{"issue":"4","key":"4591_CR4","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1590\/S1415-47572013005000040","volume":"36","author":"I Gigli","year":"2013","unstructured":"Gigli I, Maizon DO. microRNAs and the mammary gland: a new understanding of gene expression. Genet Mol Biol. 2013;36(4):465\u201374.","journal-title":"Genet Mol Biol"},{"issue":"6","key":"4591_CR5","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1534\/g3.113.009936","volume":"4","author":"N Lawless","year":"2014","unstructured":"Lawless N, Reinhardt TA, Bryan K, Baker M, Pesch B, Zimmerman D, et al. MicroRNA regulation of bovine monocyte inflammatory and metabolic networks in an in vivo infection model. G3 (Bethesda). 2014;4(6):957\u201371.","journal-title":"G3 (Bethesda)"},{"issue":"3","key":"4591_CR6","doi-asserted-by":"publisher","first-page":"e57543","DOI":"10.1371\/journal.pone.0057543","volume":"8","author":"N Lawless","year":"2013","unstructured":"Lawless N, Foroushani AB, McCabe MS, O'Farrelly C, Lynn DJ. Next generation sequencing reveals the expression of a unique miRNA profile in response to a gram-positive bacterial infection. PLoS One. 2013;8(3):e57543.","journal-title":"PLoS One"},{"key":"4591_CR7","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1186\/1471-2164-15-181","volume":"15","author":"W Jin","year":"2014","unstructured":"Jin W, Ibeagha-Awemu EM, Liang G, Beaudoin F, Zhao X, Guan le L. Transcriptome microRNA profiling of bovine mammary epithelial cells challenged with Escherichia coli or Staphylococcus aureus bacteria reveals pathogen directed microRNA expression profiles. BMC Genomics. 2014;15:181.","journal-title":"BMC Genomics"},{"key":"4591_CR8","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1186\/s12864-015-2044-9","volume":"16","author":"J Sun","year":"2015","unstructured":"Sun J, Aswath K, Schroeder SG, Lippolis JD, Reinhardt TA, Sonstegard TS. MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection. BMC Genomics. 2015;16:806.","journal-title":"BMC Genomics"},{"issue":"12","key":"4591_CR9","doi-asserted-by":"publisher","first-page":"e0145089","DOI":"10.1371\/journal.pone.0145089","volume":"10","author":"RG Shaughnessy","year":"2015","unstructured":"Shaughnessy RG, Farrell D, Riepema K, Bakker D, Gordon SV. Analysis of Biobanked serum from a Mycobacterium avium subsp paratuberculosis bovine infection model confirms the remarkable stability of circulating miRNA profiles and defines a bovine serum miRNA repertoire. PLoS One. 2015;10(12):e0145089.","journal-title":"PLoS One"},{"issue":"21","key":"4591_CR10","doi-asserted-by":"publisher","first-page":"4111","DOI":"10.1007\/s00018-015-1995-y","volume":"72","author":"A Sica","year":"2015","unstructured":"Sica A, Erreni M, Allavena P, Porta C. Macrophage polarization in pathology. Cellular and molecular life sciences : CMLS. 2015;72(21):4111\u201326.","journal-title":"Cellular and molecular life sciences : CMLS"},{"issue":"6","key":"4591_CR11","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1177\/1753425912446954","volume":"18","author":"A Duvel","year":"2012","unstructured":"Duvel A, Frank C, Schnapper A, Schuberth HJ, Sipka A. Classically or alternatively activated bovine monocyte-derived macrophages in vitro do not resemble CD163\/calprotectin biased macrophage populations in the teat. Innate immunity. 2012;18(6):886\u201396.","journal-title":"Innate immunity"},{"key":"4591_CR12","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.vetmic.2015.12.014","volume":"184","author":"HJ Jorgensen","year":"2016","unstructured":"Jorgensen HJ, Nordstoga AB, Sviland S, Zadoks RN, Solverod L, Kvitle B, et al. Streptococcus agalactiae in the environment of bovine dairy herds--rewriting the textbooks? Vet Microbiol. 2016;184:64\u201372.","journal-title":"Vet Microbiol"},{"issue":"4","key":"4591_CR13","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1128\/JCM.01424-08","volume":"47","author":"SD Manning","year":"2009","unstructured":"Manning SD, Springman AC, Lehotzky E, Lewis MA, Whittam TS, Davies HD. Multilocus sequence types associated with neonatal group B streptococcal sepsis and meningitis in Canada. J Clin Microbiol. 2009;47(4):1143\u20138.","journal-title":"J Clin Microbiol"},{"key":"4591_CR14","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1186\/1471-2164-14-891","volume":"14","author":"AM Lewandowska-Sabat","year":"2013","unstructured":"Lewandowska-Sabat AM, Boman GM, Downing A, Talbot R, Storset AK, Olsaker I. The early phase transcriptome of bovine monocyte-derived macrophages infected with Staphylococcus aureus in vitro. BMC Genomics. 2013;14:891.","journal-title":"BMC Genomics"},{"issue":"15","key":"4591_CR15","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks596","volume":"40","author":"A Untergasser","year":"2012","unstructured":"Untergasser A, Cutcutache I, Koressaar T, Ye J, Faircloth BC, Remm M, et al. Primer3--new capabilities and interfaces. Nucleic Acids Res. 2012;40(15):e115.","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"4591_CR16","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/j.tvjl.2010.11.017","volume":"189","author":"V Spalenza","year":"2011","unstructured":"Spalenza V, Girolami F, Bevilacqua C, Riondato F, Rasero R, Nebbia C, et al. Identification of internal control genes for quantitative expression analysis by real-time PCR in bovine peripheral lymphocytes. Vet J. 2011;189(3):278\u201383.","journal-title":"Vet J"},{"key":"4591_CR17","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/1471-2172-11-21","volume":"11","author":"AP Piehler","year":"2010","unstructured":"Piehler AP, Grimholt RM, Ovstebo R, Berg JP. Gene expression results in lipopolysaccharide-stimulated monocytes depend significantly on the choice of reference genes. BMC Immunol. 2010;11:21.","journal-title":"BMC Immunol"},{"issue":"13","key":"4591_CR18","doi-asserted-by":"publisher","first-page":"2205","DOI":"10.1093\/bioinformatics\/btv113","volume":"31","author":"V Capece","year":"2015","unstructured":"Capece V, Garcia Vizcaino JC, Vidal R, Rahman RU, Pena Centeno T, Shomroni O, et al. Oasis: online analysis of small RNA deep sequencing data. Bioinformatics. 2015;31(13):2205\u20137.","journal-title":"Bioinformatics"},{"issue":"1","key":"4591_CR19","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","volume":"29","author":"A Dobin","year":"2013","unstructured":"Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics. 2013;29(1):15\u201321.","journal-title":"Bioinformatics"},{"issue":"7","key":"4591_CR20","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1093\/bioinformatics\/btt656","volume":"30","author":"Y Liao","year":"2014","unstructured":"Liao Y, Smyth GK, featureCounts SW. An efficient general purpose program for assigning sequence reads to genomic features. Bioinformatics. 2014;30(7):923\u201330.","journal-title":"Bioinformatics"},{"issue":"1","key":"4591_CR21","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1093\/nar\/gkr688","volume":"40","author":"MR Friedlander","year":"2012","unstructured":"Friedlander MR, Mackowiak SD, Li N, Chen W, Rajewsky N. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res. 2012;40(1):37\u201352.","journal-title":"Nucleic Acids Res"},{"issue":"12","key":"4591_CR22","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","volume":"15","author":"MI Love","year":"2014","unstructured":"Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15(12):550.","journal-title":"Genome Biol"},{"key":"4591_CR23","doi-asserted-by":"crossref","unstructured":"Agarwal V, Bell GW, Nam JW, Bartel DP. Predicting effective microRNA target sites in mammalian mRNAs. elife. 2015;4","DOI":"10.7554\/eLife.05005"},{"issue":"Database issue","key":"4591_CR24","doi-asserted-by":"publisher","first-page":"D1228","DOI":"10.1093\/nar\/gks1147","volume":"41","author":"K Breuer","year":"2013","unstructured":"Breuer K, Foroushani AK, Laird MR, Chen C, Sribnaia A, Lo R, et al. InnateDB: systems biology of innate immunity and beyond--recent updates and continuing curation. Nucleic Acids Res. 2013;41(Database issue):D1228\u201333.","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"4591_CR25","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1038\/nri2957","volume":"11","author":"LA O'Neill","year":"2011","unstructured":"O'Neill LA, Sheedy FJ, McCoy CE. MicroRNAs: the fine-tuners of toll-like receptor signalling. Nat Rev Immunol. 2011;11(3):163\u201375.","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"4591_CR26","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","volume":"136","author":"DP Bartel","year":"2009","unstructured":"Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215\u201333.","journal-title":"Cell"},{"issue":"6","key":"4591_CR27","doi-asserted-by":"publisher","first-page":"3085","DOI":"10.1128\/IAI.01551-05","volume":"74","author":"P Henneke","year":"2006","unstructured":"Henneke P, Berner R. Interaction of neonatal phagocytes with group B streptococcus: recognition and response. Infect Immun. 2006;74(6):3085\u201395.","journal-title":"Infect Immun"},{"key":"4591_CR28","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.vetmic.2016.04.013","volume":"189","author":"KE Budd","year":"2016","unstructured":"Budd KE, Mitchell J, Keane OM. Lineage associated expression of virulence traits in bovine-adapted Staphylococcus aureus. Vet Microbiol. 2016;189:24\u201331.","journal-title":"Vet Microbiol"},{"key":"4591_CR29","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1186\/s13567-015-0268-y","volume":"46","author":"R Tassi","year":"2015","unstructured":"Tassi R, McNeilly TN, Sipka A, Zadoks RN. Correlation of hypothetical virulence traits of two Streptococcus uberis strains with the clinical manifestation of bovine mastitis. Vet Res. 2015;46:123.","journal-title":"Vet Res"},{"issue":"1","key":"4591_CR30","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/s13567-017-0461-2","volume":"48","author":"M Pang","year":"2017","unstructured":"Pang M, Sun L, He T, Bao H, Zhang L, Zhou Y, et al. Molecular and virulence characterization of highly prevalent Streptococcus agalactiae circulated in bovine dairy herds. Vet Res. 2017;48(1):65.","journal-title":"Vet Res"},{"key":"4591_CR31","first-page":"1308","volume":"7","author":"H Jiang","year":"2016","unstructured":"Jiang H, Chen M, Li T, Liu H, Gong Y, Li M. Molecular characterization of Streptococcus agalactiae causing community- and hospital-acquired infections in shanghai, China. Front Microbiol. 2016;7:1308.","journal-title":"Front Microbiol"},{"issue":"6","key":"4591_CR32","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1080\/21505594.2016.1252016","volume":"8","author":"ML Korir","year":"2017","unstructured":"Korir ML, Laut C, Rogers LM, Plemmons JA, Aronoff DM, Manning SD. Differing mechanisms of surviving phagosomal stress among group B Streptococcus strains of varying genotypes. Virulence. 2017;8(6):924\u201337.","journal-title":"Virulence"},{"issue":"28","key":"4591_CR33","doi-asserted-by":"publisher","first-page":"11499","DOI":"10.1073\/pnas.1219852110","volume":"110","author":"G Curtale","year":"2013","unstructured":"Curtale G, Mirolo M, Renzi TA, Rossato M, Bazzoni F, Locati M. Negative regulation of toll-like receptor 4 signaling by IL-10-dependent microRNA-146b. Proc Natl Acad Sci U S A. 2013;110(28):11499\u2013504.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"4591_CR34","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.gdata.2014.06.019","volume":"2","author":"V Cobos Jimenez","year":"2014","unstructured":"Cobos Jimenez V, Willemsen AM, Bradley EJ, Baas F, van Kampen AH, Kootstra NA. Next-generation sequencing of microRNAs in primary human polarized macrophages. Genomics data. 2014;2:181\u20133.","journal-title":"Genomics data"},{"issue":"4","key":"4591_CR35","doi-asserted-by":"publisher","first-page":"797","DOI":"10.3892\/ijmm.2013.1260","volume":"31","author":"Y Zhang","year":"2013","unstructured":"Zhang Y, Zhang M, Zhong M, Suo Q, Lv K. Expression profiles of miRNAs in polarized macrophages. Int J Mol Med. 2013;31(4):797\u2013802.","journal-title":"Int J Mol Med"},{"issue":"26","key":"4591_CR36","doi-asserted-by":"publisher","first-page":"21816","DOI":"10.1074\/jbc.M111.327031","volume":"287","author":"JW Graff","year":"2012","unstructured":"Graff JW, Dickson AM, Clay G, McCaffrey AP, Wilson ME. Identifying functional microRNAs in macrophages with polarized phenotypes. J Biol Chem. 2012;287(26):21816\u201325.","journal-title":"J Biol Chem"},{"issue":"23","key":"4591_CR37","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.1161\/CIRCULATIONAHA.111.087817","volume":"125","author":"G Zhuang","year":"2012","unstructured":"Zhuang G, Meng C, Guo X, Cheruku PS, Shi L, Xu H, et al. A novel regulator of macrophage activation: miR-223 in obesity-associated adipose tissue inflammation. Circulation. 2012;125(23):2892\u2013903.","journal-title":"Circulation"},{"issue":"49","key":"4591_CR38","doi-asserted-by":"publisher","first-page":"35428","DOI":"10.1074\/jbc.M112.426866","volume":"288","author":"S Banerjee","year":"2013","unstructured":"Banerjee S, Cui H, Xie N, Tan Z, Yang S, Icyuz M, et al. miR-125a-5p regulates differential activation of macrophages and inflammation. J Biol Chem. 2013;288(49):35428\u201336.","journal-title":"J Biol Chem"},{"issue":"9","key":"4591_CR39","doi-asserted-by":"publisher","first-page":"e106434","DOI":"10.1371\/journal.pone.0106434","volume":"9","author":"Y Furuse","year":"2014","unstructured":"Furuse Y, Finethy R, Saka HA, Xet-Mull AM, Sisk DM, Smith KL, et al. Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells. PLoS One. 2014;9(9):e106434.","journal-title":"PLoS One"},{"issue":"6","key":"4591_CR40","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1007\/s12275-014-3658-3","volume":"52","author":"A Shmaryahu","year":"2014","unstructured":"Shmaryahu A, Carrasco M, Valenzuela PD. Prediction of bacterial microRNAs and possible targets in human cell transcriptome. J Microbiol. 2014;52(6):482\u20139.","journal-title":"J Microbiol"},{"issue":"3","key":"4591_CR41","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1038\/ni.2537","volume":"14","author":"BR Cullen","year":"2013","unstructured":"Cullen BR. MicroRNAs as mediators of viral evasion of the immune system. Nat Immunol. 2013;14(3):205\u201310.","journal-title":"Nat Immunol"},{"issue":"2","key":"4591_CR42","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.virol.2011.01.002","volume":"411","author":"A Grundhoff","year":"2011","unstructured":"Grundhoff A, Sullivan CS. Virus-encoded microRNAs. Virology. 2011;411(2):325\u201343.","journal-title":"Virology"},{"issue":"6154","key":"4591_CR43","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1126\/science.1239705","volume":"342","author":"A Weiberg","year":"2013","unstructured":"Weiberg A, Wang M, Lin FM, Zhao H, Zhang Z, Kaloshian I, et al. Fungal small RNAs suppress plant immunity by hijacking host RNA interference pathways. Science (New York, NY). 2013;342(6154):118\u201323.","journal-title":"Science (New York, NY)"},{"issue":"2","key":"4591_CR44","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.virol.2012.08.039","volume":"433","author":"C Zhang","year":"2012","unstructured":"Zhang C, Huys A, Thibault PA, Wilson JA. Requirements for human dicer and TRBP in microRNA-122 regulation of HCV translation and RNA abundance. Virology. 2012;433(2):479\u201388.","journal-title":"Virology"},{"issue":"17","key":"4591_CR45","doi-asserted-by":"publisher","first-page":"4801","DOI":"10.1093\/nar\/gkl646","volume":"34","author":"D Schmitter","year":"2006","unstructured":"Schmitter D, Filkowski J, Sewer A, Pillai RS, Oakeley EJ, Zavolan M, et al. Effects of dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells. Nucleic Acids Res. 2006;34(17):4801\u201315.","journal-title":"Nucleic Acids Res"},{"issue":"7","key":"4591_CR46","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1038\/ncb3371","volume":"18","author":"C Baer","year":"2016","unstructured":"Baer C, Squadrito ML, Laoui D, Thompson D, Hansen SK, Kiialainen A, et al. Suppression of microRNA activity amplifies IFN-gamma-induced macrophage activation and promotes anti-tumour immunity. Nat Cell Biol. 2016;18(7):790\u2013802.","journal-title":"Nat Cell Biol"},{"issue":"3","key":"4591_CR47","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1046\/j.1365-2958.2001.02535.x","volume":"41","author":"V Ozeri","year":"2001","unstructured":"Ozeri V, Rosenshine I, Ben-Ze'Ev A, Bokoch GM, Jou TS, Hanski E. De novo formation of focal complex-like structures in host cells by invading streptococci. Mol Microbiol. 2001;41(3):561\u201373.","journal-title":"Mol Microbiol"},{"issue":"Pt 10","key":"4591_CR48","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1242\/jcs.02328","volume":"118","author":"F Agerer","year":"2005","unstructured":"Agerer F, Lux S, Michel A, Rohde M, Ohlsen K, Hauck CR. Cellular invasion by Staphylococcus aureus reveals a functional link between focal adhesion kinase and cortactin in integrin-mediated internalisation. J Cell Sci. 2005;118(Pt 10):2189\u2013200.","journal-title":"J Cell Sci"},{"issue":"10","key":"4591_CR49","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1046\/j.1462-5822.2003.00308.x","volume":"5","author":"L Plancon","year":"2003","unstructured":"Plancon L, Du Merle L, Le Friec S, Gounon P, Jouve M, Guignot J, et al. Recognition of the cellular beta1-chain integrin by the bacterial AfaD invasin is implicated in the internalization of afa-expressing pathogenic Escherichia coli strains. Cell Microbiol. 2003;5(10):681\u201393.","journal-title":"Cell Microbiol"},{"issue":"6","key":"4591_CR50","doi-asserted-by":"publisher","first-page":"2580","DOI":"10.1073\/pnas.0915139107","volume":"107","author":"R Bhat","year":"2010","unstructured":"Bhat R, Axtell R, Mitra A, Miranda M, Lock C, Tsien RW, et al. Inhibitory role for GABA in autoimmune inflammation. Proc Natl Acad Sci U S A. 2010;107(6):2580\u20135.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1\u20132","key":"4591_CR51","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.jneuroim.2007.05.013","volume":"188","author":"MG Reyes-Garcia","year":"2007","unstructured":"Reyes-Garcia MG, Hernandez-Hernandez F, Hernandez-Tellez B, Garcia-Tamayo F. GABA (a) receptor subunits RNA expression in mice peritoneal macrophages modulate their IL-6\/IL-12 production. J Neuroimmunol. 2007;188(1\u20132):64\u20138.","journal-title":"J Neuroimmunol"},{"issue":"8","key":"4591_CR52","doi-asserted-by":"publisher","first-page":"5298","DOI":"10.4049\/jimmunol.173.8.5298","volume":"173","author":"J Tian","year":"2004","unstructured":"Tian J, Lu Y, Zhang H, Chau CH, Dang HN, Kaufman DL. Gamma-aminobutyric acid inhibits T cell autoimmunity and the development of inflammatory responses in a mouse type 1 diabetes model. J Immunol. 2004;173(8):5298\u2013304.","journal-title":"J Immunol"},{"issue":"9","key":"4591_CR53","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1016\/j.molimm.2005.07.025","volume":"43","author":"S Alam","year":"2006","unstructured":"Alam S, Laughton DL, Walding A, Wolstenholme AJ. Human peripheral blood mononuclear cells express GABAA receptor subunits. Mol Immunol. 2006;43(9):1432\u201342.","journal-title":"Mol Immunol"},{"issue":"1","key":"4591_CR54","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S0165-5728(98)00264-1","volume":"96","author":"J Tian","year":"1999","unstructured":"Tian J, Chau C, Hales TG, Kaufman DL. GABA(a) receptors mediate inhibition of T cell responses. J Neuroimmunol. 1999;96(1):21\u20138.","journal-title":"J Neuroimmunol"},{"issue":"42","key":"4591_CR55","doi-asserted-by":"publisher","first-page":"17408","DOI":"10.1073\/pnas.1112660108","volume":"108","author":"MV Rajaram","year":"2011","unstructured":"Rajaram MV, Ni B, Morris JD, Brooks MN, Carlson TK, Bakthavachalu B, et al. Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b. Proc Natl Acad Sci U S A. 2011;108(42):17408\u201313.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"41","key":"4591_CR56","doi-asserted-by":"publisher","first-page":"E6172","DOI":"10.1073\/pnas.1608255113","volume":"113","author":"AC Rothchild","year":"2016","unstructured":"Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, et al. MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2016;113(41):E6172\u2013e81.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"11","key":"4591_CR57","doi-asserted-by":"publisher","first-page":"4824","DOI":"10.1128\/IAI.02251-14","volume":"82","author":"CP Verschoor","year":"2014","unstructured":"Verschoor CP, Dorrington MG, Novakowski KE, Kaiser J, Radford K, Nair P, et al. MicroRNA-155 is required for clearance of Streptococcus pneumoniae from the nasopharynx. Infect Immun. 2014;82(11):4824\u201333.","journal-title":"Infect Immun"},{"key":"4591_CR58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cellimm.2016.04.003","volume":"303","author":"F Aziz","year":"2016","unstructured":"Aziz F. The emerging role of miR-223 as novel potential diagnostic and therapeutic target for inflammatory disorders. Cell Immunol. 2016;303:1\u20136.","journal-title":"Cell Immunol"},{"issue":"11","key":"4591_CR59","doi-asserted-by":"publisher","first-page":"6397","DOI":"10.3168\/jds.2011-5173","volume":"95","author":"A Naeem","year":"2012","unstructured":"Naeem A, Zhong K, Moisa SJ, Drackley JK, Moyes KM, Loor JJ. Bioinformatics analysis of microRNA and putative target genes in bovine mammary tissue infected with Streptococcus uberis. J Dairy Sci. 2012;95(11):6397\u2013408.","journal-title":"J Dairy Sci"},{"issue":"12","key":"4591_CR60","doi-asserted-by":"publisher","first-page":"2000","DOI":"10.1093\/infdis\/jiu006","volume":"209","author":"T Zhang","year":"2014","unstructured":"Zhang T, Yu J, Zhang Y, Li L, Chen Y, Li D, et al. Salmonella enterica serovar enteritidis modulates intestinal epithelial miR-128 levels to decrease macrophage recruitment via macrophage colony-stimulating factor. J Infect Dis. 2014;209(12):2000\u201311.","journal-title":"J Infect Dis"},{"key":"4591_CR61","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1101\/cshperspect.a022137","volume":"9","author":"K Luo","year":"2017","unstructured":"Luo K. Signaling cross talk between TGF-beta\/Smad and other signaling pathways. Cold Spring Harb Perspect Biol. 2017;9:1.","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"28","key":"4591_CR62","doi-asserted-by":"publisher","first-page":"21496","DOI":"10.1074\/jbc.M109.083337","volume":"285","author":"M Zhou","year":"2010","unstructured":"Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, et al. MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression. J Biol Chem. 2010;285(28):21496\u2013507.","journal-title":"J Biol Chem"},{"issue":"11","key":"4591_CR63","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1038\/nri1943","volume":"6","author":"RS Hotchkiss","year":"2006","unstructured":"Hotchkiss RS, Nicholson DW. Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol. 2006;6(11):813\u201322.","journal-title":"Nat Rev Immunol"},{"key":"4591_CR64","doi-asserted-by":"crossref","unstructured":"Newton K, Dixit VM. Signaling in innate immunity and inflammation. Cold Spring Harb Perspect Biol. 2012;4(3)","DOI":"10.1101\/cshperspect.a006049"},{"issue":"3","key":"4591_CR65","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1038\/aps.2011.200","volume":"33","author":"L Sun","year":"2012","unstructured":"Sun L, Ye RD. Role of G protein-coupled receptors in inflammation. Acta Pharmacol Sin. 2012;33(3):342\u201350.","journal-title":"Acta Pharmacol Sin"},{"key":"4591_CR66","doi-asserted-by":"publisher","first-page":"42627","DOI":"10.1038\/srep42627","volume":"7","author":"Z Li","year":"2017","unstructured":"Li Z, Lan X, Han R, Wang J, Huang Y, Sun J, et al. miR-2478 inhibits TGFbeta1 expression by targeting the transcriptional activation region downstream of the TGFbeta1 promoter in dairy goats. Sci Rep. 2017;7:42627.","journal-title":"Sci Rep"},{"key":"4591_CR67","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1186\/1471-2164-15-137","volume":"15","author":"JM Romao","year":"2014","unstructured":"Romao JM, Jin W, He M, McAllister T, Guan le L. MicroRNAs in bovine adipogenesis: genomic context, expression and function. BMC Genomics. 2014;15:137.","journal-title":"BMC Genomics"},{"issue":"9","key":"4591_CR68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0162496","volume":"11","author":"S Muroya","year":"2016","unstructured":"Muroya S, Shibata M, Hayashi M, Oe M, Ojima K. Differences in circulating microRNAs between grazing and grain-fed wagyu cattle are associated with altered expression of intramuscular microRNA, the potential target PTEN, and Lipogenic genes. PLoS One. 2016;11(9):e0162496.","journal-title":"PLoS One"},{"issue":"11","key":"4591_CR69","doi-asserted-by":"publisher","first-page":"3076","DOI":"10.1111\/jcmm.13219","volume":"21","author":"R Wang","year":"2017","unstructured":"Wang R, Zhang YY, Lu JS, Xia BH, Yang ZX, Zhu XD, et al. The highly pathogenic H5N1 influenza a virus down-regulated several cellular MicroRNAs which target viral genome. J Cell Mol Med. 2017;21(11):3076\u201386.","journal-title":"J Cell Mol Med"},{"issue":"1","key":"4591_CR70","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/age.12099","volume":"45","author":"XG Wang","year":"2014","unstructured":"Wang XG, Huang JM, Feng MY, Ju ZH, Wang CF, Yang GW, et al. Regulatory mutations in the A2M gene are involved in the mastitis susceptibility in dairy cows. Anim Genet. 2014;45(1):28\u201337.","journal-title":"Anim Genet"},{"issue":"6","key":"4591_CR71","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1261\/rna.053959.115","volume":"22","author":"NJ Schurch","year":"2016","unstructured":"Schurch NJ, Schofield P, Gierlinski M, Cole C, Sherstnev A, Singh V, et al. How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use? RNA (New York, NY). 2016;22(6):839\u201351.","journal-title":"RNA (New York, NY)"},{"issue":"4","key":"4591_CR72","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.vetimm.2013.08.004","volume":"155","author":"P Vegh","year":"2013","unstructured":"Vegh P, Foroushani AB, Magee DA, McCabe MS, Browne JA, Nalpas NC, et al. Profiling microRNA expression in bovine alveolar macrophages using RNA-seq. Vet Immunol Immunopathol. 2013;155(4):238\u201344.","journal-title":"Vet Immunol Immunopathol"}],"container-title":["BMC Genomics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-018-4591-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12864-018-4591-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-018-4591-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T01:45:17Z","timestamp":1571190317000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgenomics.biomedcentral.com\/articles\/10.1186\/s12864-018-4591-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,10]]},"references-count":72,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["4591"],"URL":"https:\/\/doi.org\/10.1186\/s12864-018-4591-3","relation":{},"ISSN":["1471-2164"],"issn-type":[{"value":"1471-2164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,10]]},"assertion":[{"value":"16 May 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Blood sampling was conducted in accordance with the laws and regulations controlling experiments using live animals in Norway and the study was approved by the Norwegian Animal Research Authority (Norwegian Food Safety Authority; FOTS id: 8194).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"241"}}