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It was performed in accordance with the Declaration of Helsinki. Informed written consent was obtained from participants after the nature and possible consequences of the studies were explained. Specimens were de-identified and all identifying information was secured to protect subjects from risks associated with participating in genomic studies.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.Datasets used are publicly available and sources are listed in the Data Sources above and in PLAIDOH documentation (). 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