{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:27:36Z","timestamp":1787020056318,"version":"build-2736575974"},"reference-count":46,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,3,13]],"date-time":"2019-03-13T00:00:00Z","timestamp":1552435200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"crossref","award":["2015CB554203"],"award-info":[{"award-number":["2015CB554203"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the Fund of Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions"},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20180075"],"award-info":[{"award-number":["BK20180075"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genomics"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12864-019-5588-2","type":"journal-article","created":{"date-parts":[[2019,3,13]],"date-time":"2019-03-13T09:04:11Z","timestamp":1552467851000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Comparative genomic analysis of 127 Escherichia coli strains isolated from domestic animals with diarrhea in China"],"prefix":"10.1186","volume":"20","author":[{"given":"Fang","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juanfang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dezhi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianluan","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqing","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangkai","family":"Zhuge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genqiang","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjun","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,3,13]]},"reference":[{"issue":"2","key":"5588_CR1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1038\/nrmicro818","volume":"2","author":"JB Kaper","year":"2004","unstructured":"Kaper JB, Nataro JP, Mobley HL. Pathogenic Escherichia coli. Nat Rev Microbiol. 2004;2(2):123\u201340.","journal-title":"Nat Rev Microbiol"},{"key":"5588_CR2","unstructured":"Canizalez-Roman A, Flores-Villasenor HM, Gonzalez-Nunez E, Velazquez-Roman J, Vidal JE, Muro-Amador S, Alapizco-Castro G, Diaz-Quinonez JA, Leon-Sicairos N. Surveillance of Diarrheagenic Escherichia coli strains isolated from diarrhea cases from children. Adults and Elderly at Northwest of Mexico Frontiers in microbiology. 2016;7:1924."},{"issue":"12","key":"5588_CR3","doi-asserted-by":"publisher","first-page":"4082","DOI":"10.1128\/AEM.01820-06","volume":"73","author":"W Han","year":"2007","unstructured":"Han W, Liu B, Cao B, Beutin L, Kruger U, Liu H, Li Y, Liu Y, Feng L, Wang L. DNA microarray-based identification of serogroups and virulence gene patterns of Escherichia coli isolates associated with porcine postweaning diarrhea and edema disease. Appl Environ Microbiol. 2007;73(12):4082\u20138.","journal-title":"Appl Environ Microbiol"},{"issue":"4","key":"5588_CR4","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.vetmic.2006.02.013","volume":"115","author":"D Cheng","year":"2006","unstructured":"Cheng D, Sun H, Xu J, Gao S. PCR detection of virulence factor genes in Escherichia coli isolates from weaned piglets with edema disease and\/or diarrhea in China. Vet Microbiol. 2006;115(4):320\u20138.","journal-title":"Vet Microbiol"},{"issue":"23","key":"5588_CR5","doi-asserted-by":"publisher","first-page":"7371","DOI":"10.1128\/AEM.02653-13","volume":"79","author":"A Chandran","year":"2013","unstructured":"Chandran A, Mazumder A. Prevalence of diarrhea-associated virulence genes and genetic diversity in Escherichia coli isolates from fecal material of various animal hosts. Appl Environ Microbiol. 2013;79(23):7371\u201380.","journal-title":"Appl Environ Microbiol"},{"issue":"1\u20132","key":"5588_CR6","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.vetmic.2013.12.013","volume":"169","author":"RP Maluta","year":"2014","unstructured":"Maluta RP, Fairbrother JM, Stella AE, Rigobelo EC, Martinez R, de Avila FA. Potentially pathogenic Escherichia coli in healthy, pasture-raised sheep on farms and at the abattoir in Brazil. Vet Microbiol. 2014;169(1\u20132):89\u201395.","journal-title":"Vet Microbiol"},{"issue":"2","key":"5588_CR7","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1017\/S0950268802008154","volume":"130","author":"JA Orden","year":"2003","unstructured":"Orden JA, Ruiz-Santa-Quiteria JA, Blanco M, Blanco JE, Mora A, Cid D, Gonzalez EA, Blanco J, de la Fuente R. Prevalence and characterization of Vero cytotoxin-producing Escherichia coli isolated from diarrhoeic and healthy sheep and goats. Epidemiol Infect. 2003;130(2):313\u201321.","journal-title":"Epidemiol Infect"},{"issue":"1","key":"5588_CR8","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1111\/j.1865-1682.2012.01319.x","volume":"60","author":"KM Osman","year":"2013","unstructured":"Osman KM, Mustafa AM, Elhariri M, Abdelhamed GS. The distribution of Escherichia coli serovars, virulence genes, gene association and combinations and virulence genes encoding serotypes in pathogenic E. coli recovered from diarrhoeic calves, sheep and goat. Transbound Emerg Dis. 2013;60(1):69\u201378.","journal-title":"Transbound Emerg Dis"},{"issue":"2","key":"5588_CR9","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/0014-5793(89)80163-2","volume":"243","author":"MA Jalal","year":"1989","unstructured":"Jalal MA, van der Helm D. Purification and crystallization of ferric enterobactin receptor protein, FepA, from the outer membranes of Escherichia coli UT5600\/pBB2. FEBS Lett. 1989;243(2):366\u201370.","journal-title":"FEBS Lett"},{"key":"5588_CR10","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.pep.2015.05.014","volume":"114","author":"G Hagelueken","year":"2015","unstructured":"Hagelueken G, Duthie FG, Florin N, Schubert E, Schiemann O. Expression, purification and spin labelling of the ferrous iron transporter FeoB from Escherichia coli BL21 for EPR studies. Protein Expr Purif. 2015;114:30\u20136.","journal-title":"Protein Expr Purif"},{"issue":"7","key":"5588_CR11","doi-asserted-by":"publisher","first-page":"2303","DOI":"10.1128\/AEM.02405-10","volume":"77","author":"A Ostblom","year":"2011","unstructured":"Ostblom A, Adlerberth I, Wold AE, Nowrouzian FL. Pathogenicity island markers, virulence determinants malX and usp, and the capacity of Escherichia coli to persist in infants' commensal microbiotas. Appl Environ Microbiol. 2011;77(7):2303\u20138.","journal-title":"Appl Environ Microbiol"},{"issue":"3","key":"5588_CR12","doi-asserted-by":"publisher","first-page":"320","DOI":"10.7883\/yoken.JJID.2016.178","volume":"70","author":"KH Oh","year":"2017","unstructured":"Oh KH, Jung SM, Shin E, Chung GT, Seong WK, Cho SH. Comparison of Enterohemorrhagic Escherichia coli (EHEC) O157 and EHEC non-O157 isolates from patients with diarrhea in Korea. Jpn J Infect Dis. 2017;70(3):320\u20132.","journal-title":"Jpn J Infect Dis"},{"issue":"6","key":"5588_CR13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065537","volume":"8","author":"X Bai","year":"2013","unstructured":"Bai X, Zhao A, Lan R, Xin Y, Xie H, Meng Q, Jin D, Yu B, Sun H, Lu S, et al. Shiga toxin-producing Escherichia coli in yaks (Bos grunniens) from the Qinghai-Tibetan plateau, China. PloS one. 2013;8(6):e65537.","journal-title":"PloS one"},{"issue":"3","key":"5588_CR14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003510","volume":"9","author":"S Patzi-Vargas","year":"2015","unstructured":"Patzi-Vargas S, Zaidi MB, Perez-Martinez I, Leon-Cen M, Michel-Ayala A, Chaussabel D, Estrada-Garcia T. Diarrheagenic Escherichia coli carrying supplementary virulence genes are an important cause of moderate to severe diarrhoeal disease in Mexico. PLoS Negl Trop Dis. 2015;9(3):e0003510.","journal-title":"PLoS Negl Trop Dis"},{"issue":"11","key":"5588_CR15","doi-asserted-by":"publisher","first-page":"1694","DOI":"10.1086\/648069","volume":"49","author":"TJ Ochoa","year":"2009","unstructured":"Ochoa TJ, Ecker L, Barletta F, Mispireta ML, Gil AI, Contreras C, Molina M, Amemiya I, Verastegui H, Hall ER, et al. Age-related susceptibility to infection with diarrheagenic Escherichia coli among infants from Periurban areas in Lima, Peru. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2009;49(11):1694\u2013702.","journal-title":"Clinical infectious diseases : an official publication of the Infectious Diseases Society of America"},{"issue":"8","key":"5588_CR16","doi-asserted-by":"publisher","first-page":"2128","DOI":"10.1128\/JCM.00711-16","volume":"54","author":"N Imuta","year":"2016","unstructured":"Imuta N, Ooka T, Seto K, Kawahara R, Koriyama T, Kojyo T, Iguchi A, Tokuda K, Kawamura H, Yoshiie K, et al. Phylogenetic analysis of Enteroaggregative Escherichia coli (EAEC) isolates from Japan reveals emergence of CTX-M-14-producing EAEC O25:H4 clones related to sequence type 131. J Clin Microbiol. 2016;54(8):2128\u201334.","journal-title":"J Clin Microbiol"},{"key":"5588_CR17","doi-asserted-by":"publisher","first-page":"1384","DOI":"10.1016\/j.chemosphere.2015.10.010","volume":"144","author":"Q Bu","year":"2016","unstructured":"Bu Q, Wang B, Huang J, Liu K, Deng S, Wang Y, Yu G. Estimating the use of antibiotics for humans across China. Chemosphere. 2016;144:1384\u201390.","journal-title":"Chemosphere"},{"issue":"11","key":"5588_CR18","doi-asserted-by":"publisher","first-page":"6772","DOI":"10.1021\/acs.est.5b00729","volume":"49","author":"QQ Zhang","year":"2015","unstructured":"Zhang QQ, Ying GG, Pan CG, Liu YS, Zhao JL. Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling, and linkage to bacterial resistance. Environmental science & technology. 2015;49(11):6772\u201382.","journal-title":"Environmental science & technology"},{"issue":"3","key":"5588_CR19","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1089\/fpd.2004.1.178","volume":"1","author":"SE Murinda","year":"2004","unstructured":"Murinda SE, Nguyen LT, Landers TL, Draughon FA, Mathew AG, Hogan JS, Smith KL, Hancock DD, Oliver SP. Comparison of Escherichia coli isolates from humans, food, and farm and companion animals for presence of Shiga toxin-producing E. Coli virulence markers. Foodborne Pathog Dis. 2004;1(3):178\u201384.","journal-title":"Foodborne Pathog Dis"},{"key":"5588_CR20","first-page":"3","volume":"358","author":"A Leimbach","year":"2013","unstructured":"Leimbach A, Hacker J, Dobrindt U. E. Coli as an all-rounder: the thin line between commensalism and pathogenicity. Curr Top Microbiol Immunol. 2013;358:3\u201332.","journal-title":"Curr Top Microbiol Immunol"},{"issue":"Database issue","key":"5588_CR21","doi-asserted-by":"publisher","first-page":"D641","DOI":"10.1093\/nar\/gkr989","volume":"40","author":"L Chen","year":"2012","unstructured":"Chen L, Xiong Z, Sun L, Yang J, Jin Q. VFDB 2012 update: toward the genetic diversity and molecular evolution of bacterial virulence factors. Nucleic Acids Res. 2012;40(Database issue):D641\u20135.","journal-title":"Nucleic Acids Res"},{"issue":"3","key":"5588_CR22","first-page":"177","volume":"63","author":"KS Sandhu","year":"1999","unstructured":"Sandhu KS, Clarke RC, Gyles CL. Virulence markers in Shiga toxin-producing Escherichia coli isolated from cattle. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 1999;63(3):177\u201384.","journal-title":"Canadian journal of veterinary research = Revue canadienne de recherche veterinaire"},{"issue":"3","key":"5588_CR23","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/0378-1135(94)90003-5","volume":"38","author":"SJ Shin","year":"1994","unstructured":"Shin SJ, Chang YF, Timour M, Lauderdale TL, Lein DH. Hybridization of clinical Escherichia coli isolates from calves and piglets in New York state with gene probes for enterotoxins (STaP, STb, LT), Shiga-like toxins (SLT-1, SLT-II) and adhesion factors (K88, K99, F41, 987P). Vet Microbiol. 1994;38(3):217\u201325.","journal-title":"Vet Microbiol"},{"issue":"9","key":"5588_CR24","doi-asserted-by":"publisher","first-page":"2951","DOI":"10.1128\/JCM.00860-12","volume":"50","author":"F Scheutz","year":"2012","unstructured":"Scheutz F, Teel LD, Beutin L, Pierard D, Buvens G, Karch H, Mellmann A, Caprioli A, Tozzoli R, Morabito S, et al. Multicenter evaluation of a sequence-based protocol for subtyping Shiga toxins and standardizing Stx nomenclature. J Clin Microbiol. 2012;50(9):2951\u201363.","journal-title":"J Clin Microbiol"},{"issue":"5","key":"5588_CR25","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1086\/376999","volume":"188","author":"JK Jelacic","year":"2003","unstructured":"Jelacic JK, Damrow T, Chen GS, Jelacic S, Bielaszewska M, Ciol M, Carvalho HM, Melton-Celsa AR, O'Brien AD, Tarr PI. Shiga toxin-producing Escherichia coli in Montana: bacterial genotypes and clinical profiles. J Infect Dis. 2003;188(5):719\u201329.","journal-title":"J Infect Dis"},{"issue":"15","key":"5588_CR26","doi-asserted-by":"publisher","first-page":"4806","DOI":"10.1128\/AEM.00623-08","volume":"74","author":"L Beutin","year":"2008","unstructured":"Beutin L, Kruger U, Krause G, Miko A, Martin A, Strauch E. Evaluation of major types of Shiga toxin 2E-producing Escherichia coli bacteria present in food, pigs, and the environment as potential pathogens for humans. Appl Environ Microbiol. 2008;74(15):4806\u201316.","journal-title":"Appl Environ Microbiol"},{"issue":"4","key":"5588_CR27","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1016\/j.vetmic.2007.07.023","volume":"126","author":"H Vu-Khac","year":"2008","unstructured":"Vu-Khac H, Cornick NA. Prevalence and genetic profiles of Shiga toxin-producing Escherichia coli strains isolated from buffaloes, cattle, and goats in Central Vietnam. Vet Microbiol. 2008;126(4):356\u201363.","journal-title":"Vet Microbiol"},{"key":"5588_CR28","doi-asserted-by":"crossref","unstructured":"McFarland N, Bundle N, Jenkins C, Godbole G, Mikhail A, Dallman T, O\u2019Connor C, Mccarthy N, O\u2019Connell E, Treacy J et al: Recurrent seasonal outbreak of an emerging serotype of Shiga toxin-producing Escherichia coli (STEC O55:H7 Stx2a) in the south west of England, July 2014 to September 2015. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2017, 22(36).","DOI":"10.2807\/1560-7917.ES.2017.22.36.30610"},{"key":"5588_CR29","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.ijfoodmicro.2015.01.018","volume":"200","author":"X Bai","year":"2015","unstructured":"Bai X, Wang H, Xin Y, Wei R, Tang X, Zhao A, Sun H, Zhang W, Wang Y, Xu Y, et al. Prevalence and characteristics of Shiga toxin-producing Escherichia coli isolated from retail raw meats in China. Int J Food Microbiol. 2015;200:31\u20138.","journal-title":"Int J Food Microbiol"},{"issue":"1","key":"5588_CR30","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/s12917-017-0975-x","volume":"13","author":"Y Zhu","year":"2017","unstructured":"Zhu Y, Dong W, Ma J, Yuan L, Hejair HM, Pan Z, Liu G, Yao H. Characterization and virulence clustering analysis of extraintestinal pathogenic Escherichia coli isolated from swine in China. BMC Vet Res. 2017;13(1):94.","journal-title":"BMC Vet Res"},{"issue":"7","key":"5588_CR31","doi-asserted-by":"publisher","first-page":"373","DOI":"10.17236\/sat00120","volume":"159","author":"P Brand","year":"2017","unstructured":"Brand P, Gobeli S, Perreten V. Pathotyping and antibiotic resistance of porcine enterovirulent Escherichia coli strains from Switzerland (2014-2015). Schweizer Archiv fur Tierheilkunde. 2017;159(7):373\u201380.","journal-title":"Schweizer Archiv fur Tierheilkunde"},{"issue":"9","key":"5588_CR32","doi-asserted-by":"publisher","first-page":"3074","DOI":"10.1128\/JCM.00617-06","volume":"44","author":"AF Helgerson","year":"2006","unstructured":"Helgerson AF, Sharma V, Dow AM, Schroeder R, Post K, Cornick NA. Edema disease caused by a clone of Escherichia coli O147. J Clin Microbiol. 2006;44(9):3074\u20137.","journal-title":"J Clin Microbiol"},{"issue":"1","key":"5588_CR33","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S0378-1135(98)00253-3","volume":"64","author":"M Contrepois","year":"1998","unstructured":"Contrepois M, Bertin Y, Pohl P, Picard B, Girardeau JP. A study of relationships among F17 a producing enterotoxigenic and non-enterotoxigenic Escherichia coli strains isolated from diarrheic calves. Vet Microbiol. 1998;64(1):75\u201381.","journal-title":"Vet Microbiol"},{"issue":"2","key":"5588_CR34","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S1473-3099(15)00424-7","volume":"16","author":"YY Liu","year":"2016","unstructured":"Liu YY, Wang Y, Walsh TR, Yi LX, Zhang R, Spencer J, Doi Y, Tian G, Dong B, Huang X, et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infect Dis. 2016;16(2):161\u20138.","journal-title":"Lancet Infect Dis"},{"key":"5588_CR35","doi-asserted-by":"publisher","first-page":"643","DOI":"10.3389\/fmicb.2014.00643","volume":"5","author":"AO Olaitan","year":"2014","unstructured":"Olaitan AO, Morand S, Rolain JM. Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria. Front Microbiol. 2014;5:643.","journal-title":"Front Microbiol"},{"key":"5588_CR36","first-page":"562","volume":"8","author":"X Huang","year":"2017","unstructured":"Huang X, Yu L, Chen X, Zhi C, Yao X, Liu Y, Wu S, Guo Z, Yi L, Zeng Z, et al. High prevalence of Colistin resistance and mcr-1 gene in Escherichia coli isolated from food animals in China. Front Microbiol. 2017;8:562.","journal-title":"Front Microbiol"},{"key":"5588_CR37","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1186\/1471-2105-11-485","volume":"11","author":"MP Cox","year":"2010","unstructured":"Cox MP, Peterson DA, Biggs PJ. SolexaQA: at-a-glance quality assessment of Illumina second-generation sequencing data. BMC bioinformatics. 2010;11:485.","journal-title":"BMC bioinformatics"},{"key":"5588_CR38","doi-asserted-by":"crossref","unstructured":"Luo R, Liu B, Xie Y, Li Z, Huang W, Yuan J, He G, Chen Y, Pan Q, Liu Y, et al. SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler. Gigascience. 1(1):18.","DOI":"10.1186\/2047-217X-1-18"},{"issue":"14","key":"5588_CR39","doi-asserted-by":"publisher","first-page":"2068","DOI":"10.1093\/bioinformatics\/btu153","volume":"30","author":"T Seemann","year":"2014","unstructured":"Seemann T. Prokka: rapid prokaryotic genome annotation. Bioinformatics. 2014;30(14):2068\u20139.","journal-title":"Bioinformatics"},{"issue":"22","key":"5588_CR40","doi-asserted-by":"publisher","first-page":"3691","DOI":"10.1093\/bioinformatics\/btv421","volume":"31","author":"AJ Page","year":"2015","unstructured":"Page AJ, Cummins CA, Hunt M, Wong VK, Reuter S, Holden MT, Fookes M, Falush D, Keane JA, Parkhill J. Roary: rapid large-scale prokaryote pan genome analysis. Bioinformatics. 2015;31(22):3691\u20133.","journal-title":"Bioinformatics"},{"issue":"9","key":"5588_CR41","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1111\/2041-210X.12410","volume":"6","author":"JW Leigh","year":"2015","unstructured":"Leigh JW, Bryant D. PopART: full-feature software for haplotype network construction. Methods in Ecology & Evolution. 2015;6(9):1110\u20136.","journal-title":"Methods in Ecology & Evolution"},{"issue":"3\u20134","key":"5588_CR42","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/j.vetmic.2013.08.014","volume":"167","author":"II Shabana","year":"2013","unstructured":"Shabana II, Zaraket H, Suzuki H. Molecular studies on diarrhea-associated Escherichia coli isolated from humans and animals in Egypt. Vet Microbiol. 2013;167(3\u20134):532\u20139.","journal-title":"Vet Microbiol"},{"issue":"8","key":"5588_CR43","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.3201\/eid1808.111616","volume":"18","author":"NP Tau","year":"2012","unstructured":"Tau NP, Meidany P, Smith AM, Sooka A, Keddy KH. Group for enteric R, meningeal disease surveillance in south a: Escherichia coli O104 associated with human diarrhea, South Africa, 2004-2011. Emerg Infect Dis. 2012;18(8):1314\u20137.","journal-title":"Emerg Infect Dis"},{"issue":"7","key":"5588_CR44","doi-asserted-by":"publisher","first-page":"3348","DOI":"10.1128\/AAC.00419-13","volume":"57","author":"AG McArthur","year":"2013","unstructured":"McArthur AG, Waglechner N, Nizam F, Yan A, Azad MA, Baylay AJ, Bhullar K, Canova MJ, De Pascale G, Ejim L, et al. The comprehensive antibiotic resistance database. Antimicrob Agents Chemother. 2013;57(7):3348\u201357.","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"5588_CR45","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1038\/nrmicro2265","volume":"8","author":"MA Croxen","year":"2010","unstructured":"Croxen MA, Finlay BB. Molecular mechanisms of Escherichia coli pathogenicity. Nat Rev Microbiol. 2010;8(1):26\u201338.","journal-title":"Nat Rev Microbiol"},{"issue":"1","key":"5588_CR46","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1093\/dnares\/dsu043","volume":"22","author":"A Iguchi","year":"2015","unstructured":"Iguchi A, Iyoda S, Kikuchi T, Ogura Y, Katsura K, Ohnishi M, Hayashi T, Thomson NR. A complete view of the genetic diversity of the Escherichia coli O-antigen biosynthesis gene cluster. DNA research : an international journal for rapid publication of reports on genes and genomes. 2015;22(1):101\u20137.","journal-title":"DNA research : an international journal for rapid publication of reports on genes and genomes"}],"container-title":["BMC Genomics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-019-5588-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12864-019-5588-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-019-5588-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,11]],"date-time":"2020-03-11T20:11:16Z","timestamp":1583957476000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgenomics.biomedcentral.com\/articles\/10.1186\/s12864-019-5588-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,13]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["5588"],"URL":"https:\/\/doi.org\/10.1186\/s12864-019-5588-2","relation":{},"ISSN":["1471-2164"],"issn-type":[{"value":"1471-2164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,13]]},"assertion":[{"value":"8 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 March 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"F\u2009T: associate professor of College of Veterinary Medicine, Nanjing Agricultural University. J\u2009W: master student of College of Veterinary Medicine, Nanjing Agricultural University. D L: doctoral student of College of Veterinary Medicine, Nanjing Agricultural University. Song Gao: professor of College of Veterinary Medicine, Yangzhou University. J R: associate research fellow of College of Veterinary Medicine, Nanjing Agricultural University.L\u2009M: research fellow of Qinghai Academy of veterinary Medicine and Animal Science,Qinghai University. F\u2009L: staff of Institute of Microbiology, Chinese Academy of Sciences. X Z: postdoctor of College of Veterinary Medicine, Nanjing Agricultural University. G Y: professor of College of Animal Science and Technology, ShiheziUniversity. Y L: associate research fellow of Qinghai Academy of veterinary Medicine and Animal Science,Qinghai University. J D: professor of College of Veterinary Medicine, Nanjing Agricultural University.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 information"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"212"}}