{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:43:36Z","timestamp":1789008216493,"version":"build-2803163510"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"the Department of Science and Technology of Shanxi Province","award":["[20210302124494]"],"award-info":[{"award-number":["[20210302124494]"]}]},{"name":"the Department of Science and Technology of Shanxi Province","award":["[20210302124494]"],"award-info":[{"award-number":["[20210302124494]"]}]},{"name":"the Department of Science and Technology of Shanxi Province","award":["[20210302124494]"],"award-info":[{"award-number":["[20210302124494]"]}]},{"name":"the Department of Science and Technology of Shanxi Province","award":["[20210302124494]"],"award-info":[{"award-number":["[20210302124494]"]}]},{"name":"the Department of Science and Technology of Shanxi Province","award":["[20210302124494]"],"award-info":[{"award-number":["[20210302124494]"]}]},{"name":"the Department of Science and Technology of Shanxi Province","award":["[20210302124494]"],"award-info":[{"award-number":["[20210302124494]"]}]},{"name":"the Department of Science and Technology of Shanxi Province","award":["[20210302124494]"],"award-info":[{"award-number":["[20210302124494]"]}]},{"name":"the Department of Education of Shanxi Province","award":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"],"award-info":[{"award-number":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"]}]},{"name":"the Department of Education of Shanxi Province","award":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"],"award-info":[{"award-number":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"]}]},{"name":"the Department of Education of Shanxi Province","award":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"],"award-info":[{"award-number":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"]}]},{"name":"the Department of Education of Shanxi Province","award":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"],"award-info":[{"award-number":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"]}]},{"name":"the Department of Education of Shanxi Province","award":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"],"award-info":[{"award-number":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"]}]},{"name":"the Department of Education of Shanxi Province","award":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"],"award-info":[{"award-number":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"]}]},{"name":"the Department of Education of Shanxi Province","award":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"],"award-info":[{"award-number":["[J201911301, J202111303, 2020L0158, SXYBKY201713]"]}]},{"DOI":"10.13039\/501100013805","name":"Shanxi Agricultural University","doi-asserted-by":"publisher","award":["[2017YJ05]"],"award-info":[{"award-number":["[2017YJ05]"]}],"id":[{"id":"10.13039\/501100013805","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013805","name":"Shanxi Agricultural University","doi-asserted-by":"publisher","award":["[2017YJ05]"],"award-info":[{"award-number":["[2017YJ05]"]}],"id":[{"id":"10.13039\/501100013805","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013805","name":"Shanxi Agricultural University","doi-asserted-by":"publisher","award":["[2017YJ05]"],"award-info":[{"award-number":["[2017YJ05]"]}],"id":[{"id":"10.13039\/501100013805","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013805","name":"Shanxi Agricultural University","doi-asserted-by":"publisher","award":["[2017YJ05]"],"award-info":[{"award-number":["[2017YJ05]"]}],"id":[{"id":"10.13039\/501100013805","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013805","name":"Shanxi Agricultural University","doi-asserted-by":"publisher","award":["[2017YJ05]"],"award-info":[{"award-number":["[2017YJ05]"]}],"id":[{"id":"10.13039\/501100013805","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013805","name":"Shanxi Agricultural University","doi-asserted-by":"publisher","award":["[2017YJ05]"],"award-info":[{"award-number":["[2017YJ05]"]}],"id":[{"id":"10.13039\/501100013805","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013805","name":"Shanxi Agricultural University","doi-asserted-by":"publisher","award":["[2017YJ05]"],"award-info":[{"award-number":["[2017YJ05]"]}],"id":[{"id":"10.13039\/501100013805","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genomics"],"DOI":"10.1186\/s12864-024-11141-0","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T12:10:50Z","timestamp":1734523850000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["siRNA silencing and hypoxia challenge indicate that the function of common carp (Cyprinus carpio) hif-1\u03b1b genes are tightly linked to hif-1\u03b1a and hif-3\u03b1 genes"],"prefix":"10.1186","volume":"25","author":[{"given":"Xianzong","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huili","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiali","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libo","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tongyao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,18]]},"reference":[{"issue":"6","key":"11141_CR1","doi-asserted-by":"publisher","first-page":"555","DOI":"10.3390\/antiox9060555","volume":"9","author":"M Filice","year":"2020","unstructured":"Filice M, Mazza R, Leo S, Gattuso A, Cerra MC, Imbrogno S. The hypoxia tolerance of the goldfish (Carassius auratus) heart: The NOS\/NO system and beyond. Antioxidants. 2020;9(6):555.","journal-title":"Antioxidants."},{"issue":"6","key":"11141_CR2","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1086\/673180","volume":"86","author":"RS Dhillon","year":"2013","unstructured":"Dhillon RS, Yao L, Matey V, Chen BJ, Zhang AJ, Cao ZD, Fu SJ, Brauner CJ, Wang YS, Richards JG. Interspecific differences in hypoxia-induced gill remodeling in carp. Physiol Biochem Zool. 2013;86(6):727\u201339.","journal-title":"Physiol Biochem Zool"},{"key":"11141_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.907944","volume":"13","author":"N Suo","year":"2022","unstructured":"Suo N, Zhou ZX, Xu J, Cao DC, Wu BY, Zhang HY, Xu P, Zhao ZX. Transcriptome Analysis Reveals Molecular Underpinnings of Common Carp (Cyprinus carpio) Under Hypoxia Stress. Front Genet. 2022;13: 907944.","journal-title":"Front Genet"},{"key":"11141_CR4","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1146\/annurev-pathol-012513-104720","volume":"9","author":"GL Semenza","year":"2014","unstructured":"Semenza GL. Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. Annu Rev Pathol Mech Dis. 2014;9:47\u201371.","journal-title":"Annu Rev Pathol Mech Dis"},{"issue":"5","key":"11141_CR5","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1152\/physiol.00029.2010","volume":"25","author":"CT Taylor","year":"2010","unstructured":"Taylor CT, McElwain JC. Ancient atmospheres and the evolution of oxygen sensing via the hypoxia-inducible factor in metazoans. Physiology. 2010;25(5):272\u20139.","journal-title":"Physiology"},{"issue":"3","key":"11141_CR6","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1111\/cas.13483","volume":"109","author":"S Koyasu","year":"2018","unstructured":"Koyasu S, Kobayashi M, Goto Y, Hiraoka M, Harada H. Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge. Cancer Sci. 2018;109(3):560\u201371.","journal-title":"Cancer Sci"},{"issue":"3","key":"11141_CR7","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1074\/jbc.270.3.1230","volume":"270","author":"GL Wang","year":"1995","unstructured":"Wang GL, Semenza GL. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem. 1995;270(3):1230\u20137.","journal-title":"J Biol Chem"},{"issue":"3","key":"11141_CR8","first-page":"205","volume":"7","author":"YZ Gu","year":"1998","unstructured":"Gu YZ, Moran SM, Hogenesch JB, Wartman L, Bradfield CA. Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha. Gene Expr. 1998;7(3):205\u201313.","journal-title":"Gene Expr"},{"issue":"1","key":"11141_CR9","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1186\/s11658-022-00408-7","volume":"27","author":"M Jaskiewicz","year":"2022","unstructured":"Jaskiewicz M, Moszynska A, Kroliczewski J, Cabaj A, Bartoszewska S, Charzynska A, Gebert M, Dabrowski M, Collawn JF, Bartoszewski R. The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability. Cell Mol Biol Lett. 2022;27(1):109.","journal-title":"Cell Mol Biol Lett"},{"issue":"4","key":"11141_CR10","doi-asserted-by":"publisher","first-page":"C260","DOI":"10.1152\/ajpcell.00315.2015","volume":"310","author":"C Duan","year":"2016","unstructured":"Duan C. Hypoxia-inducible factor 3 biology: complexities and emerging themes. Am J Physiol Cell Physiol. 2016;310(4):C260-269.","journal-title":"Am J Physiol Cell Physiol"},{"issue":"16","key":"11141_CR11","doi-asserted-by":"publisher","first-page":"5611","DOI":"10.3390\/ijms21165611","volume":"21","author":"C Corrado","year":"2020","unstructured":"Corrado C, Fontana S. Hypoxia and HIF signaling: One axis with divergent effects. Int J Mol Sci. 2020;21(16):5611.","journal-title":"Int J Mol Sci"},{"issue":"7565","key":"11141_CR12","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1038\/nature14883","volume":"524","author":"D Wu","year":"2015","unstructured":"Wu D, Potluri N, Lu J, Kim Y, Rastinejad F. Structural integration in hypoxia-inducible factors. Nature. 2015;524(7565):303\u20138.","journal-title":"Nature"},{"key":"11141_CR13","doi-asserted-by":"publisher","first-page":"659","DOI":"10.3389\/fgene.2019.00659","volume":"10","author":"I Rashid","year":"2019","unstructured":"Rashid I, Pathak AK, Kumar R, Srivastava P, Singh M, Murali S, Kushwaha B. Genome-wide comparative analysis of HIF binding sites in Cyprinus carpio for in silico identification of functional hypoxia response elements. Front Genet. 2019;10:659.","journal-title":"Front Genet"},{"issue":"23","key":"11141_CR14","doi-asserted-by":"publisher","first-page":"e207","DOI":"10.1182\/blood-2010-10-314427","volume":"117","author":"J Schodel","year":"2011","unstructured":"Schodel J, Oikonomopoulos S, Ragoussis J, Pugh CW, Ratcliffe PJ, Mole DR. High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq. Blood. 2011;117(23):e207-217.","journal-title":"Blood"},{"issue":"1","key":"11141_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/emm.2004.1","volume":"36","author":"JW Lee","year":"2004","unstructured":"Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW. Hypoxia-inducible factor (HIF-1)\u03b1: Its protein stability and biological functions. Exp Mol Med. 2004;36(1):1\u201312.","journal-title":"Exp Mol Med"},{"issue":"2","key":"11141_CR16","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1590\/S1519-69842010000200027","volume":"70","author":"WR Barrionuevo","year":"2010","unstructured":"Barrionuevo WR, Fernandes MN, Rocha O. Aerobic and anaerobic metabolism for the zebrafish, Danio rerio, reared under normoxic and hypoxic conditions and exposed to acute hypoxia during development. Braz J Biol. 2010;70(2):425\u201334.","journal-title":"Braz J Biol"},{"issue":"Pt 22","key":"11141_CR17","doi-asserted-by":"publisher","first-page":"3802","DOI":"10.1242\/jeb.048512","volume":"213","author":"T Omlin","year":"2010","unstructured":"Omlin T, Weber JM. Hypoxia stimulates lactate disposal in rainbow trout. J Exp Biol. 2010;213(Pt 22):3802\u20139.","journal-title":"J Exp Biol"},{"issue":"4","key":"11141_CR18","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.cbpc.2008.04.012","volume":"148","author":"M Mandic","year":"2008","unstructured":"Mandic M, Lau GY, Nijjar MM, Richards JG. Metabolic recovery in goldfish: A comparison of recovery from severe hypoxia exposure and exhaustive exercise. Comp Biochem Physiol C Toxicol Pharmacol. 2008;148(4):332\u20138.","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"issue":"4","key":"11141_CR19","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1093\/molbev\/mst010","volume":"30","author":"K Katoh","year":"2013","unstructured":"Katoh K, Standley DM. MAFFT multiple sequence alignment software version 7: Improvements in performance and usability. Mol Biol Evol. 2013;30(4):772\u201380.","journal-title":"Mol Biol Evol"},{"issue":"9","key":"11141_CR20","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1093\/bioinformatics\/btu033","volume":"30","author":"A Stamatakis","year":"2014","unstructured":"Stamatakis A. RAxML version 8: A tool for phylogenetic analysis and post-analysis of large phylogenies. Bioinformatics. 2014;30(9):1312\u20133.","journal-title":"Bioinformatics"},{"issue":"6","key":"11141_CR21","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.1093\/molbev\/msw046","volume":"33","author":"J Huerta-Cepas","year":"2016","unstructured":"Huerta-Cepas J, Serra F, Bork P. ETE 3: Reconstruction, analysis, and visualization of phylogenomic data. Mol Biol Evol. 2016;33(6):1635\u20138.","journal-title":"Mol Biol Evol"},{"issue":"2","key":"11141_CR22","doi-asserted-by":"publisher","first-page":"e107","DOI":"10.1002\/imt2.107","volume":"2","author":"S Chen","year":"2023","unstructured":"Chen S. Ultrafast one-pass FASTQ data preprocessing, quality control, and deduplication using fastp. Imeta. 2023;2(2):e107.","journal-title":"Imeta"},{"issue":"4","key":"11141_CR23","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/nmeth.4197","volume":"14","author":"R Patro","year":"2017","unstructured":"Patro R, Duggal G, Love MI, Irizarry RA, Kingsford C. Salmon provides fast and bias-aware quantification of transcript expression. Nat Methods. 2017;14(4):417\u20139.","journal-title":"Nat Methods"},{"issue":"2","key":"11141_CR24","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1093\/molbev\/msp259","volume":"27","author":"M Gouy","year":"2010","unstructured":"Gouy M, Guindon S, Gascuel O. SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building. Mol Biol Evol. 2010;27(2):221\u20134.","journal-title":"Mol Biol Evol"},{"issue":"2","key":"11141_CR25","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.jconrel.2006.07.021","volume":"115","author":"H Katas","year":"2006","unstructured":"Katas H, Alpar HO. Development and characterisation of chitosan nanoparticles for siRNA delivery. J Control Release. 2006;115(2):216\u201325.","journal-title":"J Control Release"},{"issue":"4","key":"11141_CR26","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402\u20138.","journal-title":"Methods"},{"issue":"4","key":"11141_CR27","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1038\/nmeth.3317","volume":"12","author":"D Kim","year":"2015","unstructured":"Kim D, Langmead B, Salzberg SL. HISAT: a fast spliced aligner with low memory requirements. Nat Methods. 2015;12(4):357\u201360.","journal-title":"Nat Methods"},{"issue":"2","key":"11141_CR28","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1093\/bioinformatics\/btu638","volume":"31","author":"S Anders","year":"2015","unstructured":"Anders S, Pyl PT, Huber W. HTSeq\u2013a Python framework to work with high-throughput sequencing data. Bioinformatics. 2015;31(2):166\u20139.","journal-title":"Bioinformatics"},{"issue":"3","key":"11141_CR29","doi-asserted-by":"publisher","first-page":"R22","DOI":"10.1186\/gb-2011-12-3-r22","volume":"12","author":"A Roberts","year":"2011","unstructured":"Roberts A, Trapnell C, Donaghey J, Rinn JL, Pachter L. Improving RNA-Seq expression estimates by correcting for fragment bias. Genome Biol. 2011;12(3):R22.","journal-title":"Genome Biol"},{"issue":"12","key":"11141_CR30","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","volume":"15","author":"MI Love","year":"2014","unstructured":"Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15(12):550.","journal-title":"Genome Biol"},{"issue":"D1","key":"11141_CR31","doi-asserted-by":"publisher","first-page":"D330","DOI":"10.1093\/nar\/gky1055","volume":"47","author":"The Gene Ontology C","year":"2019","unstructured":"The Gene Ontology C. The Gene Ontology Resource: 20 years and still GOing strong. Nucleic Acids Res. 2019;47(D1):D330\u20138.","journal-title":"Nucleic Acids Res"},{"issue":"Database issue","key":"11141_CR32","first-page":"D480","volume":"36","author":"M Kanehisa","year":"2008","unstructured":"Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, et al. KEGG for linking genomes to life and the environment. Nucleic Acids Res. 2008;36(Database issue):D480-484.","journal-title":"Nucleic Acids Res"},{"issue":"6","key":"11141_CR33","doi-asserted-by":"publisher","first-page":"eaav0547","DOI":"10.1126\/sciadv.aav0547","volume":"5","author":"Z Chen","year":"2019","unstructured":"Chen Z, Omori Y, Koren S, Shirokiya T, Kuroda T, Miyamoto A, Wada H, Fujiyama A, Toyoda A, Zhang S, et al. De novo assembly of the goldfish (Carassius auratus) genome and the evolution of genes after whole-genome duplication. Sci Adv. 2019;5(6):eaav0547.","journal-title":"Sci Adv"},{"issue":"6","key":"11141_CR34","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1016\/j.biomaterials.2006.11.004","volume":"28","author":"X Liu","year":"2007","unstructured":"Liu X, Howard KA, Dong M, Andersen MO, Rahbek UL, Johnsen MG, Hansen OC, Besenbacher F, Kjems J. The influence of polymeric properties on chitosan\/siRNA nanoparticle formulation and gene silencing. Biomaterials. 2007;28(6):1280\u20138.","journal-title":"Biomaterials"},{"issue":"5","key":"11141_CR35","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.3390\/polym12051177","volume":"12","author":"Y Wu","year":"2020","unstructured":"Wu Y, Rashidpour A, Almajano MP, Meton I. Chitosan-Based Drug Delivery System: Applications in Fish Biotechnology. Polymers (Basel). 2020;12(5):1177.","journal-title":"Polymers (Basel)"},{"issue":"4","key":"11141_CR36","doi-asserted-by":"publisher","first-page":"53","DOI":"10.3390\/pharmaceutics9040053","volume":"9","author":"MA Mohammed","year":"2017","unstructured":"Mohammed MA, Syeda JTM, Wasan KM, Wasan EK. An Overview of Chitosan Nanoparticles and Its Application in Non-Parenteral Drug Delivery. Pharmaceutics. 2017;9(4):53.","journal-title":"Pharmaceutics"},{"issue":"5","key":"11141_CR37","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1016\/j.cocis.2013.06.005","volume":"18","author":"C Vauthier","year":"2013","unstructured":"Vauthier C, Zandanel C, Ramon AL. Chitosan-based nanoparticles for in vivo delivery of interfering agents including siRNA. Curr Opin Colloid Interface Sci. 2013;18(5):406\u201318.","journal-title":"Curr Opin Colloid Interface Sci"},{"issue":"5","key":"11141_CR38","doi-asserted-by":"publisher","first-page":"4289","DOI":"10.3390\/ijms24054289","volume":"24","author":"OR Guadarrama-Escobar","year":"2023","unstructured":"Guadarrama-Escobar OR, Serrano-Castaneda P, Anguiano-Almazan E, Vazquez-Duran A, Pena-Juarez MC, Vera-Graziano R, Morales-Florido MI, Rodriguez-Perez B, Rodriguez-Cruz IM, Miranda-Calderon JE, et al. Chitosan Nanoparticles as Oral Drug Carriers. Int J Mol Sci. 2023;24(5):4289.","journal-title":"Int J Mol Sci"},{"key":"11141_CR39","doi-asserted-by":"publisher","first-page":"3933","DOI":"10.2147\/IJN.S375229","volume":"17","author":"H Choukaife","year":"2022","unstructured":"Choukaife H, Seyam S, Alallam B, Doolaanea AA, Alfatama M. Current Advances in Chitosan Nanoparticles Based Oral Drug Delivery for Colorectal Cancer Treatment. Int J Nanomedicine. 2022;17:3933\u201366.","journal-title":"Int J Nanomedicine"},{"issue":"48","key":"11141_CR40","doi-asserted-by":"publisher","first-page":"14918","DOI":"10.1073\/pnas.1507669112","volume":"112","author":"J Inoue","year":"2015","unstructured":"Inoue J, Sato Y, Sinclair R, Tsukamoto K, Nishida M. Rapid genome reshaping by multiple-gene loss after whole-genome duplication in teleost fish suggested by mathematical modeling. Proc Natl Acad Sci USA. 2015;112(48):14918\u201323.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"11141_CR41","doi-asserted-by":"publisher","first-page":"4625","DOI":"10.1038\/s41467-019-12644-1","volume":"10","author":"P Xu","year":"2019","unstructured":"Xu P, Xu J, Liu G, Chen L, Zhou Z, Peng W, Jiang Y, Zhao Z, Jia Z, Sun Y, et al. The allotetraploid origin and asymmetrical genome evolution of the common carp Cyprinus carpio. Nat Commun. 2019;10(1):4625.","journal-title":"Nat Commun"},{"issue":"9","key":"11141_CR42","doi-asserted-by":"publisher","first-page":"1808","DOI":"10.1093\/molbev\/msl049","volume":"23","author":"FG Brunet","year":"2006","unstructured":"Brunet FG, Roest Crollius H, Paris M, Aury JM, Gibert P, Jaillon O, Laudet V, Robinson-Rechavi M. Gene loss and evolutionary rates following whole-genome duplication in teleost fishes. Mol Biol Evol. 2006;23(9):1808\u201316.","journal-title":"Mol Biol Evol"},{"issue":"6","key":"11141_CR43","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1007\/s00438-014-0889-2","volume":"289","author":"SM Glasauer","year":"2014","unstructured":"Glasauer SM, Neuhauss SC. Whole-genome duplication in teleost fishes and its evolutionary consequences. Mol Genet Genomics. 2014;289(6):1045\u201360.","journal-title":"Mol Genet Genomics"},{"issue":"7","key":"11141_CR44","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1002\/jez.b.22770","volume":"328","author":"J Pasquier","year":"2017","unstructured":"Pasquier J, Braasch I, Batzel P, Cabau C, Montfort J, Nguyen T, Jouanno E, Berthelot C, Klopp C, Journot L, et al. Evolution of gene expression after whole-genome duplication: New insights from the spotted gar genome. J Exp Zool B Mol Dev Evol. 2017;328(7):709\u201321.","journal-title":"J Exp Zool B Mol Dev Evol"},{"issue":"12","key":"11141_CR45","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1038\/nrg2482","volume":"9","author":"GC Conant","year":"2008","unstructured":"Conant GC, Wolfe KH. Turning a hobby into a job: How duplicated genes find new functions. Nat Rev Genet. 2008;9(12):938\u201350.","journal-title":"Nat Rev Genet"},{"issue":"4","key":"11141_CR46","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1006\/bbrc.2001.5659","volume":"287","author":"S Hara","year":"2001","unstructured":"Hara S, Hamada J, Kobayashi C, Kondo Y, Imura N. Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha. Biochem Biophys Res Commun. 2001;287(4):808\u201313.","journal-title":"Biochem Biophys Res Commun"},{"issue":"4","key":"11141_CR47","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1128\/MCB.01332-07","volume":"28","author":"T Yamashita","year":"2008","unstructured":"Yamashita T, Ohneda O, Nagano M, Iemitsu M, Makino Y, Tanaka H, Miyauchi T, Goto K, Ohneda K, Fujii-Kuriyama Y, et al. Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS. Mol Cell Biol. 2008;28(4):1285\u201397.","journal-title":"Mol Cell Biol"},{"issue":"23","key":"11141_CR48","doi-asserted-by":"publisher","first-page":"3885","DOI":"10.1007\/s00018-011-0679-5","volume":"68","author":"M Heikkila","year":"2011","unstructured":"Heikkila M, Pasanen A, Kivirikko KI, Myllyharju J. Roles of the human hypoxia-inducible factor (HIF)-3alpha variants in the hypoxia response. Cell Mol Life Sci. 2011;68(23):3885\u2013901.","journal-title":"Cell Mol Life Sci"},{"issue":"18","key":"11141_CR49","doi-asserted-by":"publisher","first-page":"3627","DOI":"10.1007\/s00018-019-03387-9","volume":"77","author":"JP Tolonen","year":"2020","unstructured":"Tolonen JP, Heikkila M, Malinen M, Lee HM, Palvimo JJ, Wei GH, Myllyharju J. A long hypoxia-inducible factor 3 isoform 2 is a transcription activator that regulates erythropoietin. Cell Mol Life Sci. 2020;77(18):3627\u201342.","journal-title":"Cell Mol Life Sci"},{"key":"11141_CR50","first-page":"454","volume":"21","author":"M Jaskiewicz","year":"2022","unstructured":"Jaskiewicz M, Moszynska A, Serocki M, Kroliczewski J, Bartoszewska S, Collawn JF, Bartoszewski R. Hypoxia-inducible factor (HIF)-3a2 serves as an endothelial cell fate executor during chronic hypoxia. EXCLI J. 2022;21:454\u201369.","journal-title":"EXCLI J"}],"container-title":["BMC Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-024-11141-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12864-024-11141-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-024-11141-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T13:02:43Z","timestamp":1734526963000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgenomics.biomedcentral.com\/articles\/10.1186\/s12864-024-11141-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,18]]},"references-count":50,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["11141"],"URL":"https:\/\/doi.org\/10.1186\/s12864-024-11141-0","relation":{},"ISSN":["1471-2164"],"issn-type":[{"value":"1471-2164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,18]]},"assertion":[{"value":"13 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The animal study protocol was approved by the Experimental Animal Ethics Committee of Shanxi Agricultural University (Jinzhong, China) (Approval No: SXAU-EAW-2023Cc.VH.011010178).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"1203"}}