{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T05:06:13Z","timestamp":1784091973408,"version":"3.55.0"},"reference-count":105,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":54,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Genomics"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study investigated the transcriptomic changes in the jejunum and pancreas of broiler chickens fed a diet supplemented with sugarcane bagasse (SB) to elucidate the physiological response of broilers to insoluble dietary fiber.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 168 0-day-old Ross 308 male broiler chicks were randomly allocated to two dietary treatments: a control diet or a diet supplemented with 2% SB, each consisting of six replicate pens (14 broilers\/pen). Broilers were fed starter (d 0\u201310) and grower (d 11\u201324) diets, with SB added over the top to dilute the feed. Performance parameters were measured at d 10 and 24, and RNA sequencing was conducted on six broilers\/treatment from jejunal and pancreatic tissues. Differentially expressed genes (DEGs) were identified (significant threshold at absolute log\n                      <jats:sub>2<\/jats:sub>\n                      (fold change)\u2009\u2265\u20091 and\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05) and functionally annotated using gene ontology (GO; gene counts\u2009\u2265\u20092 and\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05 as significant) analysis. Compared with the control broilers, SB-fed broilers presented significantly (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05) greater weight gain and improved feed conversion ratio at the end of the grower phase. A total of 41 (18 upregulated and 23 downregulated) jejunal and 125 (36 upregulated and 89 downregulated) pancreatic DEGs were identified from the differential expression analysis. The SB-fed broilers showed coordinated upregulation of DEGs involved in nutrient transport (\n                      <jats:italic>TRPM3<\/jats:italic>\n                      ,\n                      <jats:italic>SLC16A4<\/jats:italic>\n                      ,\n                      <jats:italic>FFAR4<\/jats:italic>\n                      , and\n                      <jats:italic>RBP4A<\/jats:italic>\n                      ), epithelial integrity (\n                      <jats:italic>WNT9A<\/jats:italic>\n                      ,\n                      <jats:italic>GAL3ST2<\/jats:italic>\n                      ,\n                      <jats:italic>TFF3<\/jats:italic>\n                      , and\n                      <jats:italic>AGR2<\/jats:italic>\n                      ), immune activation (\n                      <jats:italic>DUOX2<\/jats:italic>\n                      and\n                      <jats:italic>MHCY6<\/jats:italic>\n                      ), and growth regulation (\n                      <jats:italic>POU1F1<\/jats:italic>\n                      ). Gene ontology enrichment further revealed significant activation of biological processes, including maintenance of the gastrointestinal epithelium, gastric acid secretion, sodium ion transport, and response to oxidative stress, in the pancreatic tissue.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings reveal that SB supplementation triggers beneficial, tissue-specific transcriptomic adaptations that support nutrient uptake, epithelial repair, immune response, and oxidative balance, thereby enhancing growth. This study offers new insights into how broilers respond to dietary fiber supplementation at the transcriptomic level, supporting the strategic use of SB in sustainable poultry production.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12864-026-12978-3","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T06:33:33Z","timestamp":1779431613000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Jejunal and pancreatic transcriptomic adaptations underpin enhanced performance in broilers fed sugarcane bagasse-supplemented diets"],"prefix":"10.1186","volume":"27","author":[{"given":"Collins Amponsah","family":"Asiamah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarbast K.","family":"Kheravii","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sosthene","family":"Musigwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-Biao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"de las Heras-Saldana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"12978_CR1","doi-asserted-by":"crossref","unstructured":"Musigwa S, Cozannet P, Asiamah CA, Wu S-B. Effects of dietary protein levels, net energy levels, and essential amino acid-to-true protein ratios on broiler performance. Animals. 2024;14:3065.","DOI":"10.3390\/ani14213065"},{"issue":"11","key":"12978_CR2","doi-asserted-by":"publisher","first-page":"4006","DOI":"10.3382\/ps\/pex225","volume":"96","author":"S Kheravii","year":"2017","unstructured":"Kheravii S, Swick RA, Choct M, Wu S-B. Dietary sugarcane bagasse and coarse particle size of corn are beneficial to performance and gizzard development in broilers fed normal and high sodium diets. Poult Sci. 2017;96(11):4006\u201316.","journal-title":"Poult Sci"},{"issue":"1","key":"12978_CR3","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1186\/s40104-020-00508-4","volume":"11","author":"K Gharib-Naseri","year":"2020","unstructured":"Gharib-Naseri K, de Paula Dorigam JC, Doranalli K, Kheravii S, Swick RA, Choct M, et al. Modulations of genes related to gut integrity, apoptosis, and immunity underlie the beneficial effects of Bacillus amyloliquefaciens CECT 5940 in broilers fed diets with different protein levels in a necrotic enteritis challenge model. J Anim Sci Biotechnol. 2020;11(1):104.","journal-title":"J Anim Sci Biotechnol"},{"key":"12978_CR4","doi-asserted-by":"publisher","first-page":"100330","DOI":"10.1016\/j.gfs.2019.100330","volume":"25","author":"A Muscat","year":"2020","unstructured":"Muscat A, de Olde EM, de Boer IJM, Ripoll-Bosch R. The battle for biomass: A systematic review of food-feed-fuel competition. Glob Food Sect.\u00a0 2020;25:100330.","journal-title":"Glob Food Sec"},{"issue":"1","key":"12978_CR5","first-page":"181","volume":"11","author":"AK Singh","year":"2021","unstructured":"Singh AK, Kim WK. Effects of dietary fiber on nutrients utilization and gut health of poultry: A review of challenges and opportunities. Anim open access J MDPI. 2021;11(1):181.","journal-title":"Anim open access J MDPI"},{"issue":"1","key":"12978_CR6","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.anifeedsci.2010.08.010","volume":"162","author":"JM Gonz\u00e1lez-Alvarado","year":"2010","unstructured":"Gonz\u00e1lez-Alvarado JM, Jim\u00e9nez-Moreno E, Gonz\u00e1lez-S\u00e1nchez D, L\u00e1zaro R, Mateos GG. Effect of inclusion of oat hulls and sugar beet pulp in the diet on productive performance and digestive traits of broilers from 1 to 42 days of age. Anim Feed Sci Technol. 2010;162(1):37\u201346.","journal-title":"Anim Feed Sci Technol"},{"key":"12978_CR7","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.anifeedsci.2013.03.011","volume":"182","author":"E Jimenez Moreno","year":"2013","unstructured":"Jimenez Moreno E, Frikha M, Coca-Sinova A, Garcia J, Mateos G. Oat hulls and sugar beet pulp in diets for broilers 1. Effects on growth performance and nutrient digestibility. Anim Feed Sci Technol. 2013;182:33\u201343.","journal-title":"Anim Feed Sci Technol"},{"issue":"10","key":"12978_CR8","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.5713\/ajas.2010.90222","volume":"23","author":"M Choct","year":"2010","unstructured":"Choct M, Dersjant-Li Y, McLeish J, Peisker M. Soy oligosaccharides and soluble non-starch polysaccharides: a review of digestion, nutritive and anti-nutritive effects in pigs and poultry. Asian-Australasian J Anim Sci. 2010;23(10):1386\u201398.","journal-title":"Asian-Australasian J Anim Sci"},{"key":"12978_CR9","doi-asserted-by":"crossref","unstructured":"J\u00f8rgensen H, Zhao X-Q, Knudsen KEB, Eggum BO. The influence of dietary fibre source and level on the development of the gastrointestinal tract, digestibility and energy metabolism in broiler chickens. Br J Nutr. 1996;75(3):379\u201395.","DOI":"10.1079\/BJN19960141"},{"issue":"1","key":"12978_CR10","doi-asserted-by":"publisher","first-page":"156","DOI":"10.3382\/japr.2011-00477","volume":"21","author":"GG Mateos","year":"2012","unstructured":"Mateos GG, Jim\u00e9nez-Moreno E, Serrano MP, L\u00e1zaro RP. Poultry response to high levels of dietary fiber sources varying in physical and chemical characteristics. J Appl Poult Res. 2012;21(1):156\u201374.","journal-title":"J Appl Poult Res"},{"issue":"1","key":"12978_CR11","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/1754-6834-4-54","volume":"4","author":"CA Rezende","year":"2011","unstructured":"Rezende CA, de Lima MA, Maziero P, deAzevedo ER, Garcia W, Polikarpov I. Chemical and morphological characterization of sugarcane bagasse submitted to a delignification process for enhanced enzymatic digestibility. Biotechnol Biofuels. 2011;4(1):54.","journal-title":"Biotechnol Biofuels"},{"issue":"1","key":"12978_CR12","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1016\/j.biombioe.2010.10.018","volume":"35","author":"G Jackson de Moraes Rocha","year":"2011","unstructured":"Jackson de Moraes Rocha G, Martin C, Soares IB, Souto Maior AM, Baudel HM. Moraes de Abreu CA. Dilute mixed-acid pretreatment of sugarcane bagasse for ethanol production. Biomass Bioenergy. 2011;35(1):663\u201370.","journal-title":"Biomass Bioenergy"},{"key":"12978_CR13","doi-asserted-by":"publisher","first-page":"124262","DOI":"10.1016\/j.ijbiomac.2023.124262","volume":"239","author":"J Fangueiro","year":"2023","unstructured":"Fangueiro J, de Carvalho N, Antunes F, Mota I, Pintado M, Madureira A, et al. Lignin from sugarcane bagasse as a prebiotic additive for poultry feed. Int J Biol Macromol. 2023;239:124262.","journal-title":"Int J Biol Macromol"},{"key":"12978_CR14","doi-asserted-by":"crossref","unstructured":"Ravanal MC, Contador CA, Wong W-T, Zhang Q, Roman-Benn A, Ah-Hen KS et al. Prebiotics in animal nutrition: Harnessing agro-industrial waste for improved gut health and performance. Anim Nutr. 2025.","DOI":"10.1016\/j.aninu.2024.11.025"},{"issue":"1","key":"12978_CR15","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1186\/s12864-018-4592-2","volume":"19","author":"S Kheravii","year":"2018","unstructured":"Kheravii S, Swick RA, Choct M, Wu S-B. Upregulation of genes encoding digestive enzymes and nutrient transporters in the digestive system of broiler chickens by dietary supplementation of fiber and inclusion of coarse particle size corn. BMC Genomics. 2018;19(1):208.","journal-title":"BMC Genomics"},{"issue":"4","key":"12978_CR16","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.3382\/ps\/pex403","volume":"97","author":"S Kheravii","year":"2018","unstructured":"Kheravii S, Swick RA, Choct M, Wu S-B. Nutrient digestibility response to sugarcane bagasse addition and corn particle size in normal and high Na diets for broilers. Poult Sci. 2018;97(4):1170\u20136.","journal-title":"Poult Sci"},{"issue":"1","key":"12978_CR17","doi-asserted-by":"publisher","first-page":"104532","DOI":"10.1016\/j.psj.2024.104532","volume":"104","author":"Y Zhu","year":"2025","unstructured":"Zhu Y, Kubota S, Pasri P, Rakngam S, Okrathok S, Pukkung C, et al. Transcriptome analysis of jejunal mucosal tissue in breeder hens exposed to acute heat stress. Poult Sci. 2025;104(1):104532.","journal-title":"Poult Sci"},{"issue":"9","key":"12978_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/ani11092606","volume":"11","author":"P Sinpru","year":"2021","unstructured":"Sinpru P, Riou C, Kubota S, Poompramun C, Molee W, Molee A. Jejunal transcriptomic profiling for differences in feed conversion ratio in slow-growing chickens. Animals. 2021;11(9):1\u201323.","journal-title":"Animals"},{"key":"12978_CR19","doi-asserted-by":"crossref","unstructured":"Vertiprakhov V, Grozina A, Fisinin V. Editorial: The role of the pancreas in poultry. Front Physiol Switzerland. 2024;15:1463203.","DOI":"10.3389\/fphys.2024.1463203"},{"key":"12978_CR20","unstructured":"Aviagen. Ross broiler management. 2014. http:\/\/en.aviagen.com\/assets\/Tech_Center\/Ross_Broiler\/Ross-Broiler-Handbook-2014i-EN.pdf."},{"issue":"7","key":"12978_CR21","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1039\/AN9941901497","volume":"119","author":"HN Englyst","year":"1994","unstructured":"Englyst HN, Quigley ME, Hudson GJ. Determination of dietary fibre as non-starch polysaccharides with gas-liquid chromatographic, high-performance liquid chromatographic or spectrophotometric measurement of constituent sugars. Analyst. 1994;119(7):1497\u2013509.","journal-title":"Analyst"},{"key":"12978_CR22","doi-asserted-by":"crossref","unstructured":"Kirk TK, Obst JR. Lignin determination. Methods in enzymology. Elsevier; 1988. p.87\u2013101.","DOI":"10.1016\/0076-6879(88)61014-7"},{"key":"12978_CR23","unstructured":"Andrews S. FastQC: a quality control tool for high throughput sequence data. 2010. Available on http:\/\/www.bioinformatics.babraham.ac.uk\/projects\/fastqc. Accessed March 2022."},{"issue":"15","key":"12978_CR24","doi-asserted-by":"publisher","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","volume":"30","author":"AM Bolger","year":"2014","unstructured":"Bolger AM, Lohse M, Usadel B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics. 2014;30(15):2114\u201320.","journal-title":"Bioinformatics"},{"issue":"1","key":"12978_CR25","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","volume":"29","author":"A Dobin","year":"2013","unstructured":"Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics. 2013;29(1):15\u201321.","journal-title":"Bioinformatics"},{"issue":"10","key":"12978_CR26","doi-asserted-by":"publisher","first-page":"2943","DOI":"10.1093\/bioinformatics\/btac166","volume":"38","author":"GH Putri","year":"2022","unstructured":"Putri GH, Anders S, Pyl PT, Pimanda JE, Zanini F. Analysing high-throughput sequencing data in Python with HTSeq 2.0. Bioinformatics. 2022;38(10):2943\u20135.","journal-title":"Bioinformatics"},{"issue":"3","key":"12978_CR27","doi-asserted-by":"publisher","first-page":"R25","DOI":"10.1186\/gb-2010-11-3-r25","volume":"11","author":"MD Robinson","year":"2010","unstructured":"Robinson MD, Oshlack A. A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol. 2010;11(3):R25.","journal-title":"Genome Biol"},{"issue":"1","key":"12978_CR28","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","volume":"26","author":"MD Robinson","year":"2010","unstructured":"Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010;26(1):139\u201340.","journal-title":"Bioinformatics"},{"issue":"1","key":"12978_CR29","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1038\/nprot.2008.211","volume":"4","author":"DW Huang","year":"2009","unstructured":"Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009;4(1):44\u201357.","journal-title":"Nat Protoc"},{"key":"12978_CR30","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2021","unstructured":"R Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2021."},{"key":"12978_CR31","doi-asserted-by":"publisher","first-page":"137300","DOI":"10.1016\/j.neulet.2023.137300","volume":"809","author":"X Xu","year":"2023","unstructured":"Xu X, Li H, Lu S, Shen Y. Roles of syntaphilin and armadillo repeat-containing X-linked protein 1 in brain injury after experimental intracerebral hemorrhage. Neurosci Lett. 2023;809:137300.","journal-title":"Neurosci Lett"},{"issue":"1","key":"12978_CR32","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.cell.2007.11.024","volume":"132","author":"J-S Kang","year":"2008","unstructured":"Kang J-S, Tian J-H, Pan P-Y, Zald P, Li C, Deng C, et al. Docking of axonal mitochondria by syntaphilin controls their mobility and affects short-term facilitation. Cell. 2008;132(1):137\u201348.","journal-title":"Cell"},{"key":"12978_CR33","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.lungcan.2020.06.026","volume":"147","author":"J Yan","year":"2020","unstructured":"Yan J, Zhou X, Pan D. A case of one lung adenocarcinoma patient harboring a novel FAM179A-ALK (F1, A19) rearrangement responding to lorlatinib treatment. Lung Cancer. 2020;147:26\u20139.","journal-title":"Lung Cancer"},{"key":"12978_CR34","doi-asserted-by":"publisher","first-page":"14020252","DOI":"10.3390\/genes14020252","volume":"14","author":"JJ Velasco","year":"2023","unstructured":"Velasco JJ, Li Y, Ziganshin BA, Zafar MA, Rizzo JA, Ma D, et al. KIF6 Trp719Arg genetic variant increases risk for thoracic aortic dissection. Genes. 2023;14:14020252.","journal-title":"Genes"},{"issue":"11","key":"12978_CR35","first-page":"e00242","volume":"86","author":"G Lijuan","year":"2020","unstructured":"Lijuan G, Zhiwei G, Peng G, Weican Z, Qingsheng Q, Xuemei L. Cytophaga hutchinsonii gldN, encoding a core component of the type IX secretion system, is essential for ion assimilation, cellulose degradation, and cell motility. Appl Environ Microbiol. 2020;86(11):e00242\u201320.","journal-title":"Appl Environ Microbiol"},{"issue":"3","key":"12978_CR36","doi-asserted-by":"publisher","first-page":"103376","DOI":"10.1016\/j.psj.2023.103376","volume":"103","author":"L-H Gu","year":"2024","unstructured":"Gu L-H, Wu R-R, Zheng X-L, Fu A, Xing Z-Y, Chen Y-Y, et al. Genomic insights into local adaptation and phenotypic diversity of Wenchang chickens. Poult Sci. 2024;103(3):103376.","journal-title":"Poult Sci"},{"key":"12978_CR37","doi-asserted-by":"crossref","unstructured":"Richter AM, K\u00fcster MM, Woods ML, Walesch SK, G\u00f6kyildirim MY, Krueger M et al. RASSF10 is a TGF\u03b2-target that regulates ASPP2 and E-Cadherin expression and acts as tumor suppressor that is epigenetically downregulated in advanced cancer. Cancers. 2019;11:1976.","DOI":"10.3390\/cancers11121976"},{"issue":"12","key":"12978_CR38","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.1038\/ncb1801","volume":"10","author":"TFJ Wagner","year":"2008","unstructured":"Wagner TFJ, Loch S, Lambert S, Straub I, Mannebach S, Mathar I, et al. Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic \u03b2 cells. Nat Cell Biol. 2008;10(12):1421\u201330.","journal-title":"Nat Cell Biol"},{"key":"12978_CR39","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/j.phrs.2017.07.014","volume":"124","author":"G Thiel","year":"2017","unstructured":"Thiel G, Rubil S, Lesch A, Guethlein LA, R\u00f6ssler OG. Transient receptor potential TRPM3 channels: Pharmacology, signaling, and biological functions. Pharmacol Res. 2017;124:92\u20139.","journal-title":"Pharmacol Res"},{"issue":"1","key":"12978_CR40","doi-asserted-by":"publisher","first-page":"3205","DOI":"10.1038\/s41467-023-39016-0","volume":"14","author":"G Cui","year":"2023","unstructured":"Cui G, Dong K, Zhou J-Y, Li S, Wu Y, Han Q, et al. Spatiotemporal transcriptomic atlas reveals the dynamic characteristics and key regulators of planarian regeneration. Nat Commun. 2023;14(1):3205.","journal-title":"Nat Commun"},{"issue":"2","key":"12978_CR41","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1124\/pr.119.018762","volume":"72","author":"MA Felmlee","year":"2020","unstructured":"Felmlee MA, Jones RS, Rodriguez-Cruz V, Follman KE, Morris ME. Monocarboxylate transporters (SLC16): Function, regulation, and role in health and disease. Pharmacol Rev. 2020;72(2):466\u201385.","journal-title":"Pharmacol Rev"},{"issue":"10","key":"12978_CR42","doi-asserted-by":"publisher","first-page":"8614","DOI":"10.3390\/ijms24108614","volume":"24","author":"X Wang","year":"2023","unstructured":"Wang X, Chen X, Liu G, Cai H, Le W. The crucial roles of Pitx3 in midbrain dopaminergic neuron development and parkinson\u2019s disease-associated neurodegeneration. Int J Mol Sci. 2023;24(10):8614.","journal-title":"Int J Mol Sci"},{"key":"12978_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fimmu.2024.1302488","volume":"15","author":"M Scharr","year":"2024","unstructured":"Scharr M, Hirt B, Neckel PH. Spatial gene expression profile of Wnt-signaling components in the murine enteric nervous system. Front Immunol. 2024;15:1\u201319.","journal-title":"Front Immunol"},{"issue":"16","key":"12978_CR44","doi-asserted-by":"publisher","first-page":"191023","DOI":"10.1242\/dev.191023","volume":"147","author":"K Scott","year":"2020","unstructured":"Scott K, O\u2019Rourke R, Gillen A, Appel B. Prdm8 regulates pMN progenitor specification for motor neuron and oligodendrocyte fates by modulating the Shh signaling response. Development. 2020;147(16):191023.","journal-title":"Development"},{"key":"12978_CR45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fgene.2022.990849","volume":"13","author":"M Kanakachari","year":"2022","unstructured":"Kanakachari M, Ashwini R, Chatterjee RN. Embryonic transcriptome unravels mechanisms and pathways underlying embryonic development with respect to muscle growth, egg production, and plumage formation in native and broiler chickens. Front Genet. 2022;13:1\u201335.","journal-title":"Front Genet"},{"issue":"6","key":"12978_CR46","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1016\/j.jhep.2020.06.027","volume":"73","author":"P Dong","year":"2020","unstructured":"Dong P, Wang X, Liu L, Tang W, Ma L, Zeng W, et al. Dampened VEPH1 activates mTORC1 signaling by weakening the TSC1\/TSC2 association in hepatocellular carcinoma. J Hepatol. 2020;73(6):1446\u201359.","journal-title":"J Hepatol"},{"issue":"1","key":"12978_CR47","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/s40364-021-00345-1","volume":"10","author":"X Li","year":"2022","unstructured":"Li X, Han M, Zhang H, Liu F, Pan Y, Zhu J, et al. Structures and biological functions of zinc finger proteins and their roles in hepatocellular carcinoma. Biomark Res. 2022;10(1):2.","journal-title":"Biomark Res"},{"key":"12978_CR48","doi-asserted-by":"publisher","first-page":"1782","DOI":"10.3389\/fmicb.2019.01782","volume":"10","author":"S Wu","year":"2019","unstructured":"Wu S, Zhang J, Huang J, Li W, Liu Z, He Z, et al. Immune-related gene expression in ducks infected with waterfowl-origin H5N6 highly pathogenic avian influenza viruses. Front Microbiol. 2019;10:1782.","journal-title":"Front Microbiol"},{"issue":"5","key":"12978_CR49","doi-asserted-by":"publisher","first-page":"105027","DOI":"10.1016\/j.psj.2025.105027","volume":"104","author":"D Wang","year":"2025","unstructured":"Wang D, Zhu Y, Dong J, Zhi Y, Wei G, Kang X, et al. Exploring the functional variations of key candidate genes affecting egg production by hypothalamic-pituitary-ovarian axis in chickens. Poult Sci. 2025;104(5):105027.","journal-title":"Poult Sci"},{"issue":"6","key":"12978_CR50","doi-asserted-by":"publisher","first-page":"101167","DOI":"10.1016\/j.animal.2024.101167","volume":"18","author":"XG Wang","year":"2024","unstructured":"Wang XG, Shen MM, Lu J, Dou TC, Ma M, Guo J, et al. Genome-wide association analysis of eggshell color of an F2 generation population reveals candidate genes in chickens. animal. 2024;18(6):101167.","journal-title":"animal"},{"key":"12978_CR51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-020-19113-0","volume":"11","author":"G Dougherty","year":"2020","unstructured":"Dougherty G, Mizuno K, N\u00f6the-Menchen T, Ikawa Y, Boldt K, Ta-Shma A, et al. CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module. Nat Commun. 2020;11:1\u201320.","journal-title":"Nat Commun"},{"issue":"8","key":"12978_CR52","doi-asserted-by":"publisher","first-page":"jcs213959","DOI":"10.1242\/jcs.213959","volume":"131","author":"J Baudier","year":"2018","unstructured":"Baudier J, Jenkins ZA, Robertson SP. The filamin-B\u2013refilin axis \u2013 spatiotemporal regulators of the actin-cytoskeleton in development and disease. J Cell Sci. 2018;131(8):jcs213959.","journal-title":"J Cell Sci"},{"issue":"34","key":"12978_CR53","doi-asserted-by":"publisher","first-page":"E8027","DOI":"10.1073\/pnas.1800076115","volume":"115","author":"W-C Hsu","year":"2018","unstructured":"Hsu W-C, Chen M-Y, Hsu S-C, Huang L-R, Kao C-Y, Cheng W-H, et al. DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation. Proc Natl Acad Sci. 2018;115(34):E8027\u201336.","journal-title":"Proc Natl Acad Sci"},{"issue":"1","key":"12978_CR54","first-page":"107","volume":"6","author":"J Choi","year":"2020","unstructured":"Choi J, Li W, Schindell B, Ni L, Liu S, Zhao X, et al. Molecular cloning, tissue distribution and the expression of cystine\/glutamate exchanger (xCT, SLC7A11) in different tissues during development in broiler chickens. Anim Nutr (Zhongguo xu mu shou yi xue hui). 2020;6(1):107\u201314.","journal-title":"Anim Nutr (Zhongguo xu mu shou yi xue hui)"},{"issue":"11","key":"12978_CR55","doi-asserted-by":"publisher","first-page":"104173","DOI":"10.1016\/j.psj.2024.104173","volume":"103","author":"L Xiao","year":"2024","unstructured":"Xiao L, Chen J, He X, Zhang X, Luo W. Whole-transcriptome sequencing revealed the ceRNA regulatory network during the proliferation and differentiation of goose myoblast. Poult Sci. 2024;103(11):104173.","journal-title":"Poult Sci"},{"key":"12978_CR56","doi-asserted-by":"crossref","unstructured":"Shi K, Zhou X, Dai J, Gao Y, Gao L, Shen Y et al. Integrative transcriptomic and metabolomic analysis of muscle and liver reveals key molecular pathways influencing growth traits in Zhedong White Geese. Animals. 2025;15:1341.","DOI":"10.3390\/ani15091341"},{"issue":"1","key":"12978_CR57","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s13395-024-00367-x","volume":"14","author":"U Gurriaran-Rodriguez","year":"2024","unstructured":"Gurriaran-Rodriguez U, Kodippili K, Datzkiw D, Javandoost E, Xiao F, Rejas MT, et al. Wnt7a is required for regeneration of dystrophic skeletal muscle. Skelet Muscle. 2024;14(1):34.","journal-title":"Skelet Muscle"},{"key":"12978_CR58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fvets.2021.653413","volume":"8","author":"F Gao","year":"2021","unstructured":"Gao F, Wang P, Wang K, Fan Y, Chen Y, Chen Y. Investigation into the relationship between sperm cysteine-rich secretory protein 2 (CRISP2) and sperm fertilizing ability and fertility of boars. Front Vet Sci. 2021;8:1\u20138.","journal-title":"Front Vet Sci"},{"issue":"2","key":"12978_CR59","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.chom.2014.12.012","volume":"17","author":"K-A Lee","year":"2015","unstructured":"Lee K-A, Kim B, Bhin J, Kim DH, You H, Kim E-K, et al. Bacterial uracil modulates drosophila DUOX-dependent gut immunity via hedgehog-induced signaling endosomes. Cell Host Microbe. 2015;17(2):191\u2013204.","journal-title":"Cell Host Microbe"},{"key":"12978_CR60","doi-asserted-by":"crossref","unstructured":"Lin L, Li K, Tian B, Jia M, Wang Q, Xu C et al. Two novel functional mutations in promoter region of SCN3B gene associated with atrial fibrillation. Life. 2022;12:1794.","DOI":"10.3390\/life12111794"},{"issue":"2","key":"12978_CR61","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12041-019-1083-4","volume":"98","author":"S Yang","year":"2019","unstructured":"Yang S, Shi Z, Ou X, Liu G. Whole-genome resequencing reveals genetic indels of feathered-leg traits in domestic chickens. J Genet. 2019;98(2):1\u20138.","journal-title":"J Genet"},{"key":"12978_CR62","doi-asserted-by":"publisher","first-page":"1434509","DOI":"10.3389\/fvets.2024.1434509","volume":"11","author":"YO Fasina","year":"2024","unstructured":"Fasina YO, Obanla TO, Ekunseitan DA, Dosu G, Richardson J, Apalowo OO. Role of trefoil factors in maintaining gut health in food animals. Front Vet Sci. 2024;11:1434509.","journal-title":"Front Vet Sci"},{"issue":"42","key":"12978_CR63","doi-asserted-by":"publisher","first-page":"12962","DOI":"10.1073\/pnas.1516733112","volume":"112","author":"L Zhao","year":"2015","unstructured":"Zhao L, Spassieva S, Gable K, Gupta SD, Shi L-Y, Wang J, et al. Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration. Proc Natl Acad Sci. 2015;112(42):12962\u20137.","journal-title":"Proc Natl Acad Sci"},{"issue":"5","key":"12978_CR64","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1016\/j.jcmgh.2021.07.001","volume":"12","author":"AA Al-Shaibi","year":"2021","unstructured":"Al-Shaibi AA, Abdel-Motal UM, Hubrack SZ, Bullock AN, Al-Marri AA, Agrebi N, et al. Human AGR2 deficiency causes mucus barrier dysfunction and infantile inflammatory bowel disease. Cell Mol Gastroenterol Hepatol. 2021;12(5):1809\u201330.","journal-title":"Cell Mol Gastroenterol Hepatol"},{"issue":"1","key":"12978_CR65","doi-asserted-by":"publisher","first-page":"6483860","DOI":"10.1155\/2021\/6483860","volume":"2021","author":"X Ye","year":"2021","unstructured":"Ye X, Wu J, Li J, Wang H. Anterior gradient protein 2 promotes mucosal repair in pediatric ulcerative colitis. Biomed Res Int. 2021;2021(1):6483860.","journal-title":"Biomed Res Int"},{"key":"12978_CR66","doi-asserted-by":"publisher","first-page":"2501","DOI":"10.3390\/ijms26062501","volume":"26","author":"D Szukiewicz","year":"2025","unstructured":"Szukiewicz D. Potential therapeutic exploitation of G protein-coupled receptor 120 (GPR120\/FFAR4) signaling in obesity-related metabolic disorders. Int J Mol Sci. 2025;26:2501.","journal-title":"Int J Mol Sci"},{"issue":"19","key":"12978_CR67","first-page":"3120","volume":"13","author":"P Cordero","year":"2023","unstructured":"Cordero P, D\u00edaz-Avil\u00e9s F, Torres P, Guzm\u00e1n M, Niknafs S, Roura E, et al. The expression of amino acid and fatty acid receptors show an age-dependent pattern involving oral cavity, jejunum and lower gut sensing in broiler chickens. Anim open access J MDPI. 2023;13(19):3120.","journal-title":"Anim open access J MDPI"},{"key":"12978_CR68","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.3390\/ani13071227","volume":"13","author":"Z Cheng","year":"2023","unstructured":"Cheng Z, Hao E, Chen X, Huang C, Liu G, Chen H, et al. Dietary fiber level improve growth performance, nutrient digestibility, immune and intestinal morphology of broilers from day 22 to 42. Animals. 2023;13:1227.","journal-title":"Animals"},{"issue":"10","key":"12978_CR69","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.5713\/ab.21.0562","volume":"35","author":"Q Ali","year":"2022","unstructured":"Ali Q, Ma S, La S, Guo Z, Liu B, Gao Z, et al. Microbial short-chain fatty acids: a bridge between dietary fibers and poultry gut health - A review. Anim Biosci. 2022;35(10):1461\u201378.","journal-title":"Anim Biosci"},{"issue":"4","key":"12978_CR70","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1007\/s00424-010-0838-9","volume":"460","author":"TFJ Wagner","year":"2010","unstructured":"Wagner TFJ, Drews A, Loch S, Mohr F, Philipp SE, Lambert S, et al. TRPM3 channels provide a regulated influx pathway for zinc in pancreatic beta cells. Pfl\u00fcgers Arch - Eur J Physiol. 2010;460(4):755\u201365.","journal-title":"Pfl\u00fcgers Arch - Eur J Physiol"},{"issue":"24","key":"12978_CR71","doi-asserted-by":"publisher","first-page":"21493","DOI":"10.1074\/jbc.M300945200","volume":"278","author":"C Grimm","year":"2003","unstructured":"Grimm C, Kraft R, Sauerbruch S, Schultz G, Harteneck C. Molecular and functional characterization of the melastatin-related cation channel TRPM3. J Biol Chem. 2003;278(24):21493\u2013501.","journal-title":"J Biol Chem"},{"issue":"3","key":"12978_CR72","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1111\/j.1471-4159.2011.07441.x","volume":"119","author":"PA Zamudio-Bulcock","year":"2011","unstructured":"Zamudio-Bulcock PA, Everett J, Harteneck C, Valenzuela CF. Activation of steroid-sensitive TRPM3 channels potentiates glutamatergic transmission at cerebellar Purkinje neurons from developing rats. J Neurochem. 2011;119(3):474\u201385.","journal-title":"J Neurochem"},{"key":"12978_CR73","doi-asserted-by":"publisher","first-page":"114783","DOI":"10.1016\/j.foodres.2024.114783","volume":"192","author":"SR Bettani","year":"2024","unstructured":"Bettani SR, Borges MTMR, Soares MR, Liska GR, Rodrigues CE. da C. Relationship between the mineral content of sugarcane and its genuine derivative, non-centrifugal raw cane sugar. Food Res Int. 2024;192:114783.","journal-title":"Food Res Int"},{"issue":"5","key":"12978_CR74","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1080\/10408398.2014.953030","volume":"57","author":"K Baye","year":"2017","unstructured":"Baye K, Jean-Pierre G, Mouquet-Rivier C. The unresolved role of dietary fibers on mineral absorption. Crit Rev Food Sci Nutr. 2017;57(5):949\u201357.","journal-title":"Crit Rev Food Sci Nutr"},{"key":"12978_CR75","doi-asserted-by":"publisher","first-page":"113856","DOI":"10.1016\/j.ejmech.2021.113856","volume":"226","author":"N Kim","year":"2021","unstructured":"Kim N, Priefer R. Retinol binding protein 4 antagonists and protein synthesis inhibitors: Potential for therapeutic development. Eur J Med Chem. 2021;226:113856.","journal-title":"Eur J Med Chem"},{"key":"12978_CR76","first-page":"14","volume":"13","author":"X Guo","year":"2023","unstructured":"Guo X, Zhang H, Wang H, He X-X, Wang J-X, Wei W, et al. Identification of key modules and hub genes involved in regulating the color of chicken breast meat using WGCNA. Anim open access J MDPI. 2023;13:14.","journal-title":"Anim open access J MDPI"},{"key":"12978_CR77","doi-asserted-by":"publisher","first-page":"745849","DOI":"10.3389\/fimmu.2021.745849","volume":"12","author":"Y Duangnumsawang","year":"2021","unstructured":"Duangnumsawang Y, Zentek J, Goodarzi Boroojeni F. Development and functional properties of intestinal mucus layer in poultry. Front Immunol. 2021;12:745849.","journal-title":"Front Immunol"},{"issue":"1","key":"12978_CR78","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0377-8401(03)00163-9","volume":"108","author":"L Montagne","year":"2003","unstructured":"Montagne L, Pluske JR, Hampson DJ. A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young non-ruminant animals. Anim Feed Sci Technol. 2003;108(1):95\u2013117.","journal-title":"Anim Feed Sci Technol"},{"issue":"6","key":"12978_CR79","doi-asserted-by":"publisher","first-page":"103716","DOI":"10.1016\/j.psj.2024.103716","volume":"103","author":"E Jebessa","year":"2024","unstructured":"Jebessa E, Bello SF, Xu Y, Cai B, Tuli MD, Girma M, et al. Comprehensive analysis of differentially expressed mRNA profiles in chicken jejunum and cecum following Eimeria maxima infection. Poult Sci. 2024;103(6):103716.","journal-title":"Poult Sci"},{"issue":"5","key":"12978_CR80","first-page":"221","volume":"9","author":"M Bertocchi","year":"2019","unstructured":"Bertocchi M, Sirri F, Palumbo O, Luise D, Maiorano G, Bosi P, et al. Exploring differential transcriptome between jejunal and cecal tissue of broiler chickens. Anim open access J MDPI. 2019;9(5):221.","journal-title":"Anim open access J MDPI"},{"issue":"7880","key":"12978_CR81","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1038\/s41586-021-03967-5","volume":"598","author":"AS Luis","year":"2021","unstructured":"Luis AS, Jin C, Pereira GV, Glowacki RWP, Gugel SR, Singh S, et al. A single sulfatase is required to access colonic mucin by a gut bacterium. Nature. 2021;598(7880):332\u20137.","journal-title":"Nature"},{"key":"12978_CR82","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.biortech.2018.06.039","volume":"265","author":"W Zhang","year":"2018","unstructured":"Zhang W, You Y, Lei F, Li P, Jiang J. Acetyl-assisted autohydrolysis of sugarcane bagasse for the production of xylo-oligosaccharides without additional chemicals. Bioresour Technol. 2018;265:387\u201393.","journal-title":"Bioresour Technol"},{"key":"12978_CR83","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.indcrop.2017.05.050","volume":"107","author":"R Zheng","year":"2017","unstructured":"Zheng R, Su S, Li J, Zhao Z, Wei J, Fu X, et al. Recovery of phenolics from the ethanolic extract of sugarcane (Saccharum officinarum L.) baggase and evaluation of the antioxidant and antiproliferative activities. Ind Crops Prod. 2017;107:360\u20139.","journal-title":"Ind Crops Prod"},{"key":"12978_CR84","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.jbiotec.2020.07.001","volume":"321","author":"WF Marcondes","year":"2020","unstructured":"Marcondes WF, Milagres AMF, Arantes V. Co-production of xylo-oligosaccharides, xylose and cellulose nanofibrils from sugarcane bagasse. J Biotechnol. 2020;321:35\u201347.","journal-title":"J Biotechnol"},{"issue":"1","key":"12978_CR85","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1186\/s40104-024-01101-9","volume":"15","author":"UE Obianwuna","year":"2024","unstructured":"Obianwuna UE, Chang X, Oleforuh-Okoleh VU, Onu PN, Zhang H, Qiu K, et al. Phytobiotics in poultry: revolutionizing broiler chicken nutrition with plant-derived gut health enhancers. J Anim Sci Biotechnol. 2024;15(1):169.","journal-title":"J Anim Sci Biotechnol"},{"issue":"2","key":"12978_CR86","doi-asserted-by":"publisher","first-page":"395","DOI":"10.3390\/microorganisms10020395","volume":"10","author":"AA Shehata","year":"2022","unstructured":"Shehata AA, Yal\u00e7\u0131n S, Latorre JD, Basiouni S, Attia YA, Abd El-Wahab A, et al. Probiotics, prebiotics, and phytogenic substances for optimizing gut health in poultry. Microorganisms. 2022;10(2):395.","journal-title":"Microorganisms"},{"issue":"4","key":"12978_CR87","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1590\/1519-6984.208749","volume":"80","author":"HT Yang","year":"2020","unstructured":"Yang HT, Huang YH, Yang GW. Mini review: immunologic functions of dual oxidases in mucosal systems of vertebrates. Brazilian J Biol. 2020;80(4):948\u201356.","journal-title":"Brazilian J Biol"},{"issue":"5","key":"12978_CR88","first-page":"G933","volume":"288","author":"RA El Hassani","year":"2005","unstructured":"El Hassani RA, Benfares N, Caillou B, Talbot M, Sabourin J-C, Belotte V, et al. Dual oxidase2 is expressed all along the digestive tract. Am J Physiol Liver Physiol. 2005;288(5):G933\u201342.","journal-title":"Am J Physiol Liver Physiol"},{"issue":"2","key":"12978_CR89","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1038\/mi.2014.74","volume":"8","author":"F Sommer","year":"2015","unstructured":"Sommer F, B\u00e4ckhed F. The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium. Mucosal Immunol. 2015;8(2):372\u20139.","journal-title":"Mucosal Immunol"},{"issue":"1","key":"12978_CR90","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1186\/s40104-021-00576-0","volume":"12","author":"R Jha","year":"2021","unstructured":"Jha R, Mishra P. Dietary fiber in poultry nutrition and their effects on nutrient utilization, performance, gut health, and on the environment: a review. J Anim Sci Biotechnol. 2021;12(1):51.","journal-title":"J Anim Sci Biotechnol"},{"issue":"1","key":"12978_CR91","doi-asserted-by":"publisher","first-page":"17965","DOI":"10.1038\/s41598-021-97306-3","volume":"11","author":"LM Hul","year":"2021","unstructured":"Hul LM, Ibelli AMG, Savoldi IR, Marcelino DEP, Fernandes LT, Peixoto JO, et al. Differentially expressed genes in the femur cartilage transcriptome clarify the understanding of femoral head separation in chickens. Sci Rep. 2021;11(1):17965.","journal-title":"Sci Rep"},{"key":"12978_CR92","doi-asserted-by":"publisher","first-page":"2035","DOI":"10.3390\/ani11072035","volume":"11","author":"C Lumsangkul","year":"2021","unstructured":"Lumsangkul C, Tapingkae W, Sringarm K, Jaturasitha S, Le Xuan C, Wannavijit S, et al. Effect of dietary sugarcane bagasse supplementation on growth performance, immune response, and immune and antioxidant-related gene expressions of Nile tilapia (Oreochromis niloticus) cultured under biofloc system. Animals. 2021;11:2035.","journal-title":"Animals"},{"issue":"7","key":"12978_CR93","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1101\/gad.3.7.946","volume":"3","author":"HJ Mangalam","year":"1989","unstructured":"Mangalam HJ, Albert VR, Ingraham HA, Kapiloff M, Wilson L, Nelson C, et al. A pituitary POU domain protein, Pit-1, activates both growth hormone and prolactin promoters transcriptionally. Genes Dev. 1989;3(7):946\u201358.","journal-title":"Genes Dev"},{"issue":"8","key":"12978_CR94","doi-asserted-by":"publisher","first-page":"3130","DOI":"10.1073\/pnas.88.8.3130","volume":"88","author":"HJ Steinfelder","year":"1991","unstructured":"Steinfelder HJ, Hauser P, Nakayama Y, Radovick S, McClaskey JH, Taylor T, et al. Thyrotropin-releasing hormone regulation of human TSHB expression: role of a pituitary-specific transcription factor (Pit-1\/GHF-1) and potential interaction with a thyroid hormone-inhibitory element. Proc Natl Acad Sci. 1991;88(8):3130\u20134.","journal-title":"Proc Natl Acad Sci"},{"issue":"4","key":"12978_CR95","doi-asserted-by":"publisher","first-page":"600","DOI":"10.5713\/ab.24.0347","volume":"38","author":"S Yan","year":"2025","unstructured":"Yan S, Gao C, Tian K, Xiao C, Shi J, Jia X, et al. Comparative population genomics analysis for chicken body sizes using genome-wide single nucleotide polymorphisms. Anim Biosci. 2025;38(4):600\u201311.","journal-title":"Anim Biosci"},{"issue":"5","key":"12978_CR96","doi-asserted-by":"publisher","first-page":"643","DOI":"10.5713\/ajas.17.0354","volume":"31","author":"P Manjula","year":"2018","unstructured":"Manjula P, Choi N, Seo D, Lee JH. POU class 1 homeobox 1 gene polymorphisms associated with growth traits in Korean native chicken. Asian-Australasian J Anim Sci. 2018;31(5):643\u20139.","journal-title":"Asian-Australasian J Anim Sci"},{"issue":"3","key":"12978_CR97","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/j.ygcen.2005.09.013","volume":"145","author":"MP Richards","year":"2006","unstructured":"Richards MP, Poch SM, McMurtry JP. Characterization of turkey and chicken ghrelin genes, and regulation of ghrelin and ghrelin receptor mRNA levels in broiler chickens. Gen Comp Endocrinol. 2006;145(3):298\u2013310.","journal-title":"Gen Comp Endocrinol"},{"key":"12978_CR98","doi-asserted-by":"publisher","first-page":"278","DOI":"10.3389\/fendo.2019.00278","volume":"10","author":"T Kitazawa","year":"2019","unstructured":"Kitazawa T, Kaiya H. Regulation of gastrointestinal motility by motilin and ghrelin in vertebrates. Front Endocrinol (Lausanne). 2019;10:278.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"2","key":"12978_CR99","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1002\/j.2040-4603.2018.tb00022.x","volume":"8","author":"H Xu","year":"2018","unstructured":"Xu H, Ghishan FK, Kiela PR. SLC9 gene family: Function, expression, and regulation. Compr Physiol. 2018;8(2):555\u201383.","journal-title":"Compr Physiol"},{"key":"12978_CR100","doi-asserted-by":"crossref","unstructured":"Gruss A, Borez\u00e9e-Durant E, Lechardeur D. Chapter Three - Environmental heme utilization by heme-auxotrophic bacteria. In: Poole RKBT-A in MP, editor. Advances in Bacterial Respiratory Physiology. Academic; 2012. p.69\u2013124.","DOI":"10.1016\/B978-0-12-394423-8.00003-2"},{"issue":"5","key":"12978_CR101","doi-asserted-by":"publisher","first-page":"87","DOI":"10.5539\/gjhs.v6n5p87","volume":"6","author":"AA Khan","year":"2014","unstructured":"Khan AA, Rahmani AH, Aldebasi YH, Aly SM. Biochemical and pathological studies on peroxidases -an updated review. Glob J Health Sci. 2014;6(5):87\u201398.","journal-title":"Glob J Health Sci"},{"issue":"45","key":"12978_CR102","doi-asserted-by":"publisher","first-page":"80093","DOI":"10.18632\/oncotarget.20278","volume":"8","author":"Y Jiao","year":"2017","unstructured":"Jiao Y, Wang Y, Guo S, Wang G. Glutathione peroxidases as oncotargets. Oncotarget. 2017;8(45):80093\u2013102.","journal-title":"Oncotarget"},{"issue":"6","key":"12978_CR103","doi-asserted-by":"publisher","first-page":"110485","DOI":"10.1016\/j.ygeno.2022.110485","volume":"114","author":"X Zhao","year":"2022","unstructured":"Zhao X, Zhang J, Wang H, Li H, Qu C, Wen J, et al. Genomic and transcriptomic analyses reveal genetic adaptation to cold conditions in the chickens. Genomics. 2022;114(6):110485.","journal-title":"Genomics"},{"issue":"5","key":"12978_CR104","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/j.jobcr.2023.07.002","volume":"13","author":"MV Kamal","year":"2023","unstructured":"Kamal MV, Damerla RR, Dikhit PS, Kumar NAN. Prostaglandin-endoperoxide synthase 2 (PTGS2) gene expression and its association with genes regulating the VEGF signaling pathway in head and neck squamous cell carcinoma. J Oral Biol Craniofac Res. 2023;13(5):567\u201374.","journal-title":"J Oral Biol Craniofac Res"},{"key":"12978_CR105","unstructured":"Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Membrane Proteins. 2002."}],"container-title":["BMC Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12864-026-12978-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-026-12978-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12864-026-12978-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T04:25:45Z","timestamp":1784089545000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12864-026-12978-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,22]]},"references-count":105,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["12978"],"URL":"https:\/\/doi.org\/10.1186\/s12864-026-12978-3","relation":{},"ISSN":["1471-2164"],"issn-type":[{"value":"1471-2164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,22]]},"assertion":[{"value":"22 August 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All broiler management procedures, including health, care, and use of laboratory animals, were fulfilled with the Australian Code for the Care and Use of Animals for Scientific Purposes. The Animal Ethics Committee of the University of New England approved the animal experimental protocols described in this study (approval number AEC 15\u2013053).","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"620"}}