{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:05:24Z","timestamp":1762542324186},"reference-count":12,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Immunol"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1186\/s12865-014-0057-9","type":"journal-article","created":{"date-parts":[[2014,12,8]],"date-time":"2014-12-08T17:36:05Z","timestamp":1418060165000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Genomic locus on chromosome 1 regulates susceptibility to spontaneous arthritis in mice deficiency of IL-1RA"],"prefix":"10.1186","volume":"15","author":[{"given":"Nan","family":"Deng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Jiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhong","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonghui","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen A","family":"Hasty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David D","family":"Brand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John M","family":"Stuart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weikuan","family":"Gu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,12,9]]},"reference":[{"key":"57_CR1","doi-asserted-by":"publisher","first-page":"3461","DOI":"10.1002\/art.23957","volume":"58","author":"MI Koenders","year":"2008","unstructured":"Koenders MI, Devesa I, Marijnissen RJ, Abdollahi-Roodsaz S, Boots AMH, Walgreen B, di Padova FE, Nicklin MJH, Joosten LAB, van den Berg WB: Interleukin-1 drives pathogenic Th17. Cells during spontaneous arthritis in interleukin-1 receptor antagonist\u2013deficient mice. Arthiritis Rheum. 2008, 58: 3461-3470. 10.1002\/art.23957.","journal-title":"Arthiritis Rheum"},{"key":"57_CR2","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.1172\/JCI20742","volume":"114","author":"R Horai","year":"2004","unstructured":"Horai R, Nakajima A, Habiro K, Kotani M, Nakae S, Matsuki T, Nambu A, Saijo S, Kotaki H, Sudo K, Okahara A, Tanioka H, Ikuse T, Ishii N, Schwartzberg PL, Abe R, Iwakura Y: TNF\u03b1 is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice. J Clin Invest. 2004, 114: 1603-1611. 10.1172\/JCI20742.","journal-title":"J Clin Invest"},{"key":"57_CR3","doi-asserted-by":"publisher","first-page":"3731","DOI":"10.1002\/art.21481","volume":"52","author":"F Zhou","year":"2005","unstructured":"Zhou F, He X, Iwakura Y, Horai R, Stuart JM: Arthritis in mice that are deficient in interleukin-1 receptor antagonist is dependent on genetic background. Arthritis Rheum. 2005, 52: 3731-10.1002\/art.21481. PubMed","journal-title":"Arthritis Rheum"},{"key":"57_CR4","first-page":"1","volume":"18","author":"Y Jiao","year":"2011","unstructured":"Jiao Y, Jiao F, Yan J, Xiong Q, Shriner D, Hasty K, Stuart J, Gu W: Identifying a major locus that regulates spontaneous arthritis in IL-1ra-deficient mice and analysis of potential candidates. Genet Res (Camb). 2011, 18: 1-9.","journal-title":"Genet Res (Camb)"},{"issue":"6","key":"57_CR5","doi-asserted-by":"publisher","first-page":"e68158","DOI":"10.1371\/journal.pone.0068158","volume":"8","author":"Y Cao","year":"2013","unstructured":"Cao Y, Liu X, Deng N, Jiao Y, Ma Y, Hasty KA, Stuart JM, Gu W: Congenic mice provide evidence for a genetic locus that modulates spontaneous arthritis caused by deficiency of IL-1RA. PLoS One. 2013, 8 (6): e68158-10.1371\/journal.pone.0068158. doi:10.1371\/journal.pone.0068158. Print 2013","journal-title":"PLoS One"},{"issue":"4","key":"57_CR6","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1128\/IAI.05680-11","volume":"80","author":"T Washino","year":"2012","unstructured":"Washino T, Moroda M, Iwakura Y, Aosai F: Toxoplasma gondii infection inhibits Th17-mediated spontaneous development of arthritis in interleukin-1 receptor antagonist-deficient mice. Infect Immun. 2012, 80 (4): 1437-1444. 10.1128\/IAI.05680-11.","journal-title":"Infect Immun"},{"issue":"11","key":"57_CR7","doi-asserted-by":"publisher","first-page":"3461","DOI":"10.1002\/art.23957","volume":"58","author":"MI Koenders","year":"2008","unstructured":"Koenders MI, Devesa I: Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist\u2013deficient mice. Arthiritis Rheum. 2008, 58 (11): 3461-3470. 10.1002\/art.23957. doi:10.1002\/art.23957","journal-title":"Arthiritis Rheum"},{"issue":"Suppl 7","key":"57_CR8","doi-asserted-by":"publisher","first-page":"S75","DOI":"10.1186\/1753-6561-3-s7-s75","volume":"3","author":"CH Huang","year":"2009","unstructured":"Huang CH, Cong L, Xie J, Qiao B, Lo SH, Zheng T: Rheumatoid arthritis-associated gene-gene interaction network for rheumatoid arthritis candidate genes. BMC Proc. 2009, 3 (Suppl 7): S75-10.1186\/1753-6561-3-s7-s75.","journal-title":"BMC Proc"},{"issue":"4","key":"57_CR9","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1128\/IAI.06081-11","volume":"80","author":"S Weber","year":"2012","unstructured":"Weber S, Tian H, van Rooijen N, Pirofski LA: A serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibody requires Fc\u03b3 receptor III and macrophages to mediate protection against pneumococcal pneumonia in mice. Infect Immun. 2012, 80 (4): 1314-1322. 10.1128\/IAI.06081-11.","journal-title":"Infect Immun"},{"issue":"7","key":"57_CR10","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1002\/eji.201242779","volume":"43","author":"GL Stephens","year":"2013","unstructured":"Stephens GL, Wang Q, Swerdlow B, Bhat G, Kolbeck R, Fung M: Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands. Eur J Immunol. 2013, 43 (7): 1727-1734. 10.1002\/eji.201242779.","journal-title":"Eur J Immunol"},{"issue":"2","key":"57_CR11","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.jgg.2013.01.001","volume":"40","author":"J Yan","year":"2013","unstructured":"Yan J, Jiao Y, Chen H, Jiao F, Hasty KA, Stuart JM, Gu W: Dual effects of IL-1 overactivity on the immune system in a mouse model of arthritis due to deficiency of IL-1 receptor antagonist. J Genet Genomics. 2013, 40 (2): 83-91. 10.1016\/j.jgg.2013.01.001.","journal-title":"J Genet Genomics"},{"issue":"1","key":"57_CR12","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1172\/JCI32639","volume":"118","author":"S Abdollahi-Roodsaz","year":"2008","unstructured":"Abdollahi-Roodsaz S, Joosten LAB: Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis. J Clin Invest. 2008, 118 (1): 205-216. 10.1172\/JCI32639.","journal-title":"J Clin Invest"}],"container-title":["BMC Immunology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12865-014-0057-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12865-014-0057-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12865-014-0057-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12865-014-0057-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T06:54:57Z","timestamp":1630565697000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcimmunol.biomedcentral.com\/articles\/10.1186\/s12865-014-0057-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["57"],"URL":"https:\/\/doi.org\/10.1186\/s12865-014-0057-9","relation":{},"ISSN":["1471-2172"],"issn-type":[{"value":"1471-2172","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"21 July 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2014","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 November 2014","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2014","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"57"}}