{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:01:43Z","timestamp":1789185703726,"version":"build-2803163510"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","funder":[{"name":"National Health Laboratory Service Research Trust","award":["94442"],"award-info":[{"award-number":["94442"]}]},{"name":"Bill and Melinda Gates Foundation (US)","award":["307494010064512"],"award-info":[{"award-number":["307494010064512"]}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["087622"],"award-info":[{"award-number":["087622"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["104992"],"award-info":[{"award-number":["104992"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Microbiol"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12866-017-0942-5","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T13:20:23Z","timestamp":1487683223000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Molecular characterization of invasive capsule null Neisseria meningitidis in South Africa"],"prefix":"10.1186","volume":"17","author":[{"given":"Karistha","family":"Ganesh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mushal","family":"Allam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Wolter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly B.","family":"Bratcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odile B.","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Lucidarme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ray","family":"Borrow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"de Gouveia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Meiring","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Birkhead","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin C. J.","family":"Maiden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"von Gottberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mignon","family":"du Plessis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,2,21]]},"reference":[{"key":"942_CR1","doi-asserted-by":"crossref","first-page":"5939","DOI":"10.1128\/IAI.66.12.5939-5947.1998","volume":"66","author":"CM Kahler","year":"1998","unstructured":"Kahler CM, Martin LE, Shih GC, Rahman MM, Carlson RW, Stephens DS. The (alpha2--\u2009>\u20098)-linked polysialic acid capsule and lipooligosaccharide structure both contribute to the ability of serogroup B Neisseria meningitidis to resist the bactericidal activity of normal human serum. Infect Immun. 1998;66:5939\u201347.","journal-title":"Infect Immun"},{"key":"942_CR2","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3201\/eid1904.111799","volume":"19","author":"OB Harrison","year":"2013","unstructured":"Harrison OB, Claus H, Jiang Y, et al. Description and nomenclature of Neisseria meningitidis capsule locus. Emerg Infect Dis. 2013;19:566\u201373.","journal-title":"Emerg Infect Dis"},{"key":"942_CR3","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1073\/pnas.86.5.1669","volume":"86","author":"M Frosch","year":"1989","unstructured":"Frosch M, Weisgerber C, Meyer TF. Molecular characterization and expression in Escherichia coli of the gene complex encoding the polysaccharide capsule of Neisseria meningitidis group B. Proc Natl Acad Sci U S A. 1989;86:1669\u201373.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"942_CR4","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1111\/j.1365-2958.1994.tb00367.x","volume":"11","author":"S Hammerschmidt","year":"1994","unstructured":"Hammerschmidt S, Birkholz C, Zahringer U, et al. Contribution of genes from the capsule gene complex (cps) to lipooligosaccharide biosynthesis and serum resistance in Neisseria meningitidis. Mol Microbiol. 1994;11:885\u201396.","journal-title":"Mol Microbiol"},{"issue":"11","key":"942_CR5","doi-asserted-by":"crossref","first-page":"3342","DOI":"10.1128\/jb.178.11.3342-3345.1996","volume":"178","author":"H Petering","year":"1996","unstructured":"Petering H, Hammerschmidt S, Frosch M, van Putten JPM, Ison CA, Robertson BD. Genes associated with meningococcal capsule complex are also found in Neisseria gonorrhoeae. J Bacteriol. 1996;178(11):3342\u20135.","journal-title":"J Bacteriol"},{"key":"942_CR6","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1099\/00221287-148-6-1813","volume":"148","author":"H Claus","year":"2002","unstructured":"Claus H, Maiden MCJ, Maag R, Frosch M, Vogel U. Many carried meningococci lack the genes required for capsule synthesis and transport. Microbiology. 2002;148:1813\u20139.","journal-title":"Microbiology"},{"key":"942_CR7","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1086\/374740","volume":"187","author":"JM Dolan-Livengood","year":"2003","unstructured":"Dolan-Livengood JM, Miller YK, Martin LE, Urwin R, Stephens DS. Genetic basis for nongroupable Neisseria meningitidis. J Infect Dis. 2003;187:1616\u201328.","journal-title":"J Infect Dis"},{"key":"942_CR8","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1086\/512084","volume":"195","author":"H Findlow","year":"2007","unstructured":"Findlow H, Vogel U, Mueller JE, et al. Three cases of invasive meningococcal disease caused by a capsule null locus strain circulating among healthy carriers in Burkina Faso. J Infect Dis. 2007;195:1071\u20137.","journal-title":"J Infect Dis"},{"key":"942_CR9","doi-asserted-by":"crossref","first-page":"e38","DOI":"10.1086\/427875","volume":"40","author":"LM Hoang","year":"2005","unstructured":"Hoang LM, Thomas E, Tyler S, et al. Rapid and fatal meningococcal disease due to a strain of Neisseria meningitidis containing the capsule null locus. Clin Infect Dis. 2005;40:e38\u201342.","journal-title":"Clin Infect Dis"},{"key":"942_CR10","doi-asserted-by":"crossref","first-page":"2346","DOI":"10.1128\/IAI.00293-12","volume":"80","author":"KO Johswich","year":"2012","unstructured":"Johswich KO, Zhou J, Law DK, et al. Invasive potential of nonencapsulated disease isolates of Neisseria meningitidis. Infect Immun. 2012;80:2346\u201353.","journal-title":"Infect Immun"},{"key":"942_CR11","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1128\/JCM.42.7.2898-2901.2004","volume":"42","author":"U Vogel","year":"2004","unstructured":"Vogel U, Claus H, von Muller L, Bunjes D, Elias J, Frosch M. Bacteremia in an immunocompromised patient caused by a commensal Neisseria meningitidis strain harboring the capsule null locus (cnl). J Clin Microbiol. 2004;42:2898\u2013901.","journal-title":"J Clin Microbiol"},{"key":"942_CR12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/INF.0000000000000949","volume":"47","author":"Z Xu","year":"2015","unstructured":"Xu Z, Zhu B, Xu L, Gao Y, Shao Z. First case of Neisseria meningitidis capsule null locus infection in China. Infect Dis (Lond). 2015;47:1\u20132.","journal-title":"Infect Dis (Lond)"},{"key":"942_CR13","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1086\/428590","volume":"191","author":"H Claus","year":"2005","unstructured":"Claus H, Maiden MCJ, Wilson DJ, et al. Genetic analysis of meningococci carried by children and young adults. J Infect Dis. 2005;191:1263\u201371.","journal-title":"J Infect Dis"},{"key":"942_CR14","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1093\/infdis\/jir466","volume":"204","author":"AB Ibarz-Pavon","year":"2011","unstructured":"Ibarz-Pavon AB, Maclennan J, Andrews NJ, et al. Changes in serogroup and genotype prevalence among carried meningococci in the United Kingdom during vaccine implementation. J Infect Dis. 2011;204:1046\u201353.","journal-title":"J Infect Dis"},{"key":"942_CR15","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.vaccine.2011.11.050","volume":"30","author":"H Claus","year":"2012","unstructured":"Claus H, Jordens MS, Kriz P, et al. Capsule null locus meningococci: typing of antigens used in an investigational multicomponent meningococcus serogroup B vaccine. Vaccine. 2012;30:155\u201360.","journal-title":"Vaccine"},{"key":"942_CR16","doi-asserted-by":"crossref","first-page":"10834","DOI":"10.1073\/pnas.0603940103","volume":"103","author":"MM Giuliani","year":"2006","unstructured":"Giuliani MM, Adu-Bobie J, Comanducci M, et al. A universal vaccine for serogroup B meningococcus. Proc Natl Acad Sci U S A. 2006;103:10834\u20139.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"942_CR17","doi-asserted-by":"crossref","first-page":"6086","DOI":"10.1016\/j.vaccine.2010.06.083","volume":"28","author":"HQ Jiang","year":"2010","unstructured":"Jiang HQ, Hoiseth SK, Harris SL, et al. Broad vaccine coverage predicted for a bivalent recombinant factor H binding protein based vaccine to prevent serogroup B meningococcal disease. Vaccine. 2010;28:6086\u201393.","journal-title":"Vaccine"},{"key":"942_CR18","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1186\/s12879-014-0663-4","volume":"14","author":"PA Kristiansen","year":"2014","unstructured":"Kristiansen PA, Ba AK, Ouedraogo AS, et al. Persistent low carriage of serogroup A Neisseria meningitidis two years after mass vaccination with the meningococcal conjugate vaccine, MenAfriVac. BMC Infect Dis. 2014;14:663.","journal-title":"BMC Infect Dis"},{"key":"942_CR19","doi-asserted-by":"crossref","first-page":"e101","DOI":"10.1371\/journal.pmed.0040101","volume":"4","author":"J Leimkugel","year":"2007","unstructured":"Leimkugel J, Hodgson A, Forgor AA, et al. Clonal waves of Neisseria colonisation and disease in the African meningitis belt: eight-year longitudinal study in northern Ghana. PLoS Med. 2007;4:e101.","journal-title":"PLoS Med"},{"key":"942_CR20","doi-asserted-by":"crossref","first-page":"847","DOI":"10.3201\/eid1306.061395","volume":"13","author":"JE Mueller","year":"2007","unstructured":"Mueller JE, Sangare L, Njanpop-Lafourcade BM, et al. Molecular characteristics and epidemiology of meningococcal carriage, Burkina Faso, 2003. Emerg Infect Dis. 2007;13:847\u201354.","journal-title":"Emerg Infect Dis"},{"key":"942_CR21","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1093\/clinids\/18.5.780","volume":"18","author":"CA Fijen","year":"1994","unstructured":"Fijen CA, Kuijper EJ, Tjia HG, Daha MR, Dankert J. Complement deficiency predisposes for meningitis due to nongroupable meningococci and Neisseria-related bacteria. Clin Infect Dis. 1994;18:780\u20134.","journal-title":"Clin Infect Dis"},{"key":"942_CR22","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1093\/infdis\/155.4.815","volume":"155","author":"DS Hummell","year":"1987","unstructured":"Hummell DS, Mocca LF, Frasch CE, et al. Meningitis caused by a nonencapsulated strain of Neisseria meningitidis in twin infants with a C6 deficiency. J Infect Dis. 1987;155:815\u20138.","journal-title":"J Infect Dis"},{"key":"942_CR23","first-page":"169","volume":"21","author":"AS Kemp","year":"1985","unstructured":"Kemp AS, Vernon J, Muller-Eberhard HJ, Bau DC. Complement C8 deficiency with recurrent meningococcemia: examination of meningococcal opsonization. Aust Paediatr J. 1985;21:169\u201371.","journal-title":"Aust Paediatr J"},{"key":"942_CR24","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1365-2249.2011.04525.x","volume":"167","author":"A Orren","year":"2012","unstructured":"Orren A, Owen EP, Henderson HE, et al. Complete deficiency of the sixth complement component (C6Q0), susceptibility to Neisseria meningitidis infections and analysis of the frequencies of C6Q0 gene defects in South Africans. Clin Exp Immunol. 2012;167:459\u201371.","journal-title":"Clin Exp Immunol"},{"key":"942_CR25","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.molimm.2014.11.010","volume":"64","author":"EP Owen","year":"2015","unstructured":"Owen EP, Wurzner R, Leisegang F, et al. A complement C5 gene mutation, c.754G\u2009>\u2009A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases. Mol Immunol. 2015;64:170\u20136.","journal-title":"Mol Immunol"},{"key":"942_CR26","doi-asserted-by":"crossref","first-page":"2395","DOI":"10.1001\/archinte.1990.00390220127027","volume":"150","author":"M Zoppi","year":"1990","unstructured":"Zoppi M, Weiss M, Nydegger UE, Hess T, Sp\u00e4th PJ. Recurrent meningitis in a patient with congenital deficiency of the C9 component of complement. First case of C9 deficiency in Europe. Arch Intern Med. 1990;150:2395\u20139.","journal-title":"Arch Intern Med"},{"issue":"Suppl 2","key":"942_CR27","doi-asserted-by":"crossref","first-page":"B64","DOI":"10.1016\/j.vaccine.2009.04.061","volume":"27","author":"DA Caugant","year":"2009","unstructured":"Caugant DA, Maiden MCJ. Meningococcal carriage and disease\u2014population biology and evolution. Vaccine. 2009;27 Suppl 2:B64\u201370.","journal-title":"Vaccine"},{"key":"942_CR28","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1146\/annurev.micro.59.030804.121325","volume":"60","author":"MCJ Maiden","year":"2006","unstructured":"Maiden MCJ. Multilocus sequence typing of bacteria. Annu Rev Microbiol. 2006;60:561\u201388.","journal-title":"Annu Rev Microbiol"},{"issue":"7","key":"942_CR29","doi-asserted-by":"crossref","first-page":"e11835","DOI":"10.1371\/journal.pone.0011835","volume":"5","author":"PR Marri","year":"2010","unstructured":"Marri PR, Paniscus M, Weyand NJ, et al. Genome sequencing reveals widespread virulence gene exchange among human Neisseria species. PLoS One. 2010;5(7):e11835.","journal-title":"PLoS One"},{"issue":"9","key":"942_CR30","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1073\/pnas.0800151105","volume":"105","author":"C Schoen","year":"2008","unstructured":"Schoen C, Blom J, Claus H, et al. Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis. Proc Natl Acad Sci U S A. 2008;105(9):3473\u20138.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"942_CR31","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1471-2164-7-128","volume":"7","author":"LA Snyder","year":"2006","unstructured":"Snyder LA, Saunders NJ. The majority of genes in the pathogenic Neisseria species are present in non-pathogenic Neisseria lactamica, including those designated as \u2018virulence genes\u2019. BMC Genomics. 2006;7:128.","journal-title":"BMC Genomics"},{"issue":"4","key":"942_CR32","doi-asserted-by":"crossref","first-page":"e18441","DOI":"10.1371\/journal.pone.0018441","volume":"6","author":"B Joseph","year":"2011","unstructured":"Joseph B, Schwarz RF, Linke B, et al. Virulence evolution of the human pathogen Neisseria meningitidis by recombination in the core and accessory genome. PLoS One. 2011;6(4):e18441.","journal-title":"PLoS One"},{"key":"942_CR33","first-page":"924","volume":"89","author":"RE Huebner","year":"1999","unstructured":"Huebner RE, Klugman KP, Matai U, Eggers R, Hussey G. Laboratory surveillance for Haemophilus influenzae type B meningococcal, and pneumococcal disease. Haemophilus Surveillance Working Group. S Afr Med J. 1999;89:924\u20135.","journal-title":"S Afr Med J"},{"key":"942_CR34","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1086\/525260","volume":"46","author":"A Gottberg von","year":"2008","unstructured":"von Gottberg A, du Plessis M, Cohen C, et al. Emergence of endemic serogroup W135 meningococcal disease associated with a high mortality rate in South Africa. Clin Infect Dis. 2008;46:377\u201386.","journal-title":"Clin Infect Dis"},{"key":"942_CR35","doi-asserted-by":"crossref","first-page":"e19361","DOI":"10.1371\/journal.pone.0019361","volume":"6","author":"J Dolan Thomas","year":"2011","unstructured":"Dolan Thomas J, Hatcher CP, Satterfield DA, et al. sodC-based real-time PCR for detection of Neisseria meningitidis. PLoS One. 2011;6:e19361.","journal-title":"PLoS One"},{"key":"942_CR36","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1128\/JCM.06087-11","volume":"50","author":"X Wang","year":"2012","unstructured":"Wang X, Theodore MJ, Mair R, et al. Clinical validation of multiplex real-time PCR assays for detection of bacterial meningitis pathogens. J Clin Microbiol. 2012;50:702\u20138.","journal-title":"J Clin Microbiol"},{"key":"942_CR37","volume-title":"Koneman\u2019s color atlas and textbook of diagnostic microbiology","author":"W Winn","year":"2006","unstructured":"Winn W, Allen S, Janda W, et al. Koneman\u2019s color atlas and textbook of diagnostic microbiology. 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2006.","edition":"6"},{"key":"942_CR38","volume-title":"M100-S24 Performance standards for antimicrobial susceptibility testing; twenty-fourth informational supplement","author":"Clinical and Laboratory Standards Institute","year":"2014","unstructured":"Clinical and Laboratory Standards Institute. M100-S24 Performance standards for antimicrobial susceptibility testing; twenty-fourth informational supplement. 24th ed. Wayne: Clinical and Laboratory Standards Institute; 2014.","edition":"24"},{"key":"942_CR39","first-page":"Unit 11.5","volume":"Chapter 11","author":"DR Zerbino","year":"2010","unstructured":"Zerbino DR. Using the Velvet de novo assembler for short-read sequencing technologies. Curr Protoc Bioinformatics. 2010;Chapter 11:Unit 11.5.","journal-title":"Curr Protoc Bioinformatics"},{"key":"942_CR40","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1101\/gr.074492.107","volume":"18","author":"DR Zerbino","year":"2008","unstructured":"Zerbino DR, Birney E. Velvet: algorithms for de novo short read assembly using de Bruijn graphs. Genome Res. 2008;18:821\u20139.","journal-title":"Genome Res"},{"key":"942_CR41","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1186\/1471-2105-11-595","volume":"11","author":"KA Jolley","year":"2010","unstructured":"Jolley KA, Maiden MCJ. BIGSdb: Scalable analysis of bacterial genome variation at the population level. BMC Bioinformatics. 2010;11:595.","journal-title":"BMC Bioinformatics"},{"key":"942_CR42","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1128\/JCM.03529-13","volume":"52","author":"JS Bennett","year":"2014","unstructured":"Bennett JS, Watkins ER, Jolley KA, Harrison OB, Maiden MCJ. Identifying Neisseria species by use of the 50S ribosomal protein L6 (rplF) gene. J Clin Microbiol. 2014;52:1375\u201381.","journal-title":"J Clin Microbiol"},{"key":"942_CR43","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1099\/mic.0.027995-0","volume":"155","author":"C Brehony","year":"2009","unstructured":"Brehony C, Wilson DJ, Maiden MCJ. Variation of the factor H-binding protein of Neisseria meningitidis. Microbiology. 2009;155:4155\u201369.","journal-title":"Microbiology"},{"key":"942_CR44","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1084\/jem.20020407","volume":"195","author":"M Comanducci","year":"2002","unstructured":"Comanducci M, Bambini S, Brunelli B, et al. NadA, a novel vaccine candidate of Neisseria meningitidis. J Exp Med. 2002;195:1445\u201354.","journal-title":"J Exp Med"},{"key":"942_CR45","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1574-6976.2006.00057.x","volume":"31","author":"KA Jolley","year":"2007","unstructured":"Jolley KA, Brehony C, Maiden MCJ. Molecular typing of meningococci: recommendations for target choice and nomenclature. FEMS Microbiol Rev. 2007;31:89\u201396.","journal-title":"FEMS Microbiol Rev"},{"key":"942_CR46","doi-asserted-by":"crossref","first-page":"3770","DOI":"10.1073\/pnas.0915162107","volume":"107","author":"D Serruto","year":"2010","unstructured":"Serruto D, Spadafina T, Ciucchi L, et al. Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans. Proc Natl Acad Sci U S A. 2010;107:3770\u20135.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"942_CR47","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1186\/1471-2164-15-1138","volume":"15","author":"HB Bratcher","year":"2014","unstructured":"Bratcher HB, Corton C, Jolley KA, Parkhill J, Maiden MCJ. A gene-by-gene population genomics platform: de novo assembly, annotation and genealogical analysis of 108 representative Neisseria meningitidis genomes. BMC Genomics. 2014;15:1138.","journal-title":"BMC Genomics"},{"key":"942_CR48","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1099\/mic.0.055459-0","volume":"158","author":"KA Jolley","year":"2012","unstructured":"Jolley KA, Bliss CM, Bennett JS, et al. Ribosomal multilocus sequence typing: universal characterization of bacteria from domain to strain. Microbiology. 2012;158:1005\u201315.","journal-title":"Microbiology"},{"key":"942_CR49","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1073\/pnas.95.6.3140","volume":"95","author":"MCJ Maiden","year":"1998","unstructured":"Maiden MCJ, Bygraves JA, Feil E, et al. Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci U S A. 1998;95:3140\u20135.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"942_CR50","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/bioinformatics\/14.1.68","volume":"14","author":"DH Huson","year":"1998","unstructured":"Huson DH. SplitsTree: analyzing and visualizing evolutionary data. Bioinformatics. 1998;14:68\u201373.","journal-title":"Bioinformatics"},{"key":"942_CR51","doi-asserted-by":"crossref","first-page":"4653","DOI":"10.1128\/IAI.73.8.4653-4667.2005","volume":"73","author":"S Hammerschmidt","year":"2005","unstructured":"Hammerschmidt S, Wolff S, Hocke A, Rosseau S, Muller E, Rohde M. Illustration of pneumococcal polysaccharide capsule during adherence and invasion of epithelial cells. Infect Immun. 2005;73:4653\u201367.","journal-title":"Infect Immun"}],"container-title":["BMC Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12866-017-0942-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T19:50:26Z","timestamp":1601668226000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcmicrobiol.biomedcentral.com\/articles\/10.1186\/s12866-017-0942-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,21]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["942"],"URL":"https:\/\/doi.org\/10.1186\/s12866-017-0942-5","relation":{},"ISSN":["1471-2180"],"issn-type":[{"value":"1471-2180","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,21]]},"article-number":"40"}}