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Infections of <jats:italic>Scedosporium<\/jats:italic> have been reported in several immunocompromised and immunocompetent patients with a high mortality rate. Recently, we have isolated and identified several <jats:italic>Scedosporium<\/jats:italic> strains during an environmental survey in Thailand.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We describe the isolate, TMMI-012, possibly a new species isolated from soils in the Chatuchak public park, Bangkok, Thailand. TMMI-012 is phylogenetically related to the <jats:italic>Scedosporium<\/jats:italic> genus and is a sibling to <jats:italic>S. boydii<\/jats:italic> but shows distinct morphological and pathological characteristics. It is fast growing and highly resistant to antifungal drugs and abiotic stresses<jats:italic>.<\/jats:italic> Pathological studies of in vitro and in vivo models confirm its high virulence and pathogenicity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>TMMI-012 is considered a putative novel <jats:italic>Scedosporium<\/jats:italic> species. The high antifungal resistance of TMMI-012 compared with its sibling, <jats:italic>Scedosporium<\/jats:italic> species is likely related to its clinical impact on human health.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12866-021-02105-5","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T19:09:38Z","timestamp":1612897778000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Phenomic profiling of a novel sibling species within the Scedosporium complex in Thailand"],"prefix":"10.1186","volume":"21","author":[{"given":"T.","family":"Kitisin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ampawong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Muangkaew","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Sukphopetch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,9]]},"reference":[{"issue":"1","key":"2105_CR1","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1128\/CMR.00039-07","volume":"21","author":"KJ Cortez","year":"2008","unstructured":"Cortez KJ, Roilides E, Quiroz-Telles F, Meletiadis J, Antachopoulos C, Knudsen T, Buchanan W, Milanovich J, Sutton DA, Fothergill A, et al. 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BALB\/cMlac mice (8-week old, female) were purchased from National Laboratory Animal Center, Mahidol University. All mouse colonies were maintained according to the local regulatory guideline and hygiene monitoring. Mouse experiments were approved by Institutional Animal Care and Use Committee (IACUC) of Khon Kaen University, Thailand (approval number: 0514.1.75\/34).<i>Galleria mellonella<\/i> (200\u2013400\u2009mg body weight in last larvae stage) were obtained from Jerry\u00ae Wax Worms (Thailand). Larvae were maintained according to the approved protocols for an in vivo work by the research ethics committee of Mahidol University, Thailand (approval certificate number: MU-IACUC 2018\/015). Moreover, the present study has been reported in compliance with the ARRIVE guidelines (Animal Research: Reporting in Vivo Experiments).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"42"}}