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Aberrant gut colonization in early life may predispose children to various diseases in adulthood. However, the associations between gut microbial changes and GBS colonization is still unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The composition and diversity of meconium microbiota in GBS group were similar to that of healthy controls. However, we identified several specific taxa that were differentially abundant between the two groups (linear discriminant analysis (LDA) effect size (LEfSe):\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05, LDA\u2009&gt;\u20092.0). Particularly, the relative abundance of\n                      <jats:italic>Lactobacillus paracasei<\/jats:italic>\n                      was significantly reduced, indicating a role in GBS colonization.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study presented a series of bacterial species colonized by GBS, thus providing novel evidence in support of initial intestinal microbiota dysbiosis in the neonates with mother\u2019s GBS colonization.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12866-021-02204-3","type":"journal-article","created":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T04:03:07Z","timestamp":1620187387000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Deviations in the gut microbiota of neonates affected by maternal group B Streptococcus colonization"],"prefix":"10.1186","volume":"21","author":[{"given":"Yue-feng","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-lei","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-xiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kejian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-hua","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,5]]},"reference":[{"issue":"3","key":"2204_CR1","first-page":"689","volume":"56","author":"JM Koenig","year":"2009","unstructured":"Koenig JM, Keenan WJ. 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Under the procedure approved by the Institutional Review Board (registry number: LL201804007), written informed consent was given and approved by the parents of the newborns.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"140"}}