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Microbiological quality of drinking water supplied in Moamba, a small town in southern Mozambique, was assessed by collecting and analyzing 91 water sample from 5 sampling sites: raw or inlet water, treated water and 3 household taps along the water distribution system. The presence of <jats:italic>Escherichia coli<\/jats:italic> as indicator fecal contamination, three bacterial pathogens, <jats:italic>Vibrio cholerae<\/jats:italic>, <jats:italic>Salmonella<\/jats:italic> and <jats:italic>Campylobacter<\/jats:italic> spp., and Cefotaximee resistant <jats:italic>E. coli<\/jats:italic> as antibiotic resistance determinant, was assessed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>. The results showed fecal contamination in all types of water samples: <jats:italic>E. coli<\/jats:italic> was found in 100% of inlet water samples, in 21% of treated water samples, and in 22% of tap water samples. No <jats:italic>Salmonella<\/jats:italic> spp. was detected during the study. The presence of <jats:italic>V. cholerae<\/jats:italic> was detected in 42% of all water samples tested: 100% of inlet water samples, in 16% of treated water samples, and in 23% household tap water samples. All <jats:italic>V. cholerae<\/jats:italic> confirmed isolates where genotyped by PCR as non-O1\/non-O139; however, 9 isolates showed the presence of the genes encoding for cholera toxin. The presence of <jats:italic>Campylobacter<\/jats:italic> spp. was detected in 36% of the water samples tested: in 95% of inlet water samples, in 10% of treated water samples and in 23% household tap water samples. Cefotaxime resistant <jats:italic>E. coli<\/jats:italic> was detected in 63% of inlet water, 16% of treated water, and in 9% of tap water samples, these isolates were also resistant to multiple other antibiotics: ampicillin, streptomycin, tetracycline chloramphenicol. All 70 <jats:italic>V. cholerae<\/jats:italic> non-O1\/non-O139 confirmed isolated were resistant to ampicillin, 51% to streptomycin, 13% to gentamycin, and 1 isolate was resistant to tetracycline; 13% showed a multi-drug resistant profile, being resistant to at least three antibiotics.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>. The presence of fecal contamination and pathogens in the water treatment system and household taps in Moamba indicates a health risk for the population. This burden increases by the presence of bacterial pathogens showing multidrug resistance.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12866-022-02654-3","type":"journal-article","created":{"date-parts":[[2022,10,8]],"date-time":"2022-10-08T09:02:59Z","timestamp":1665219779000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Occurrence of waterborne pathogens and antibiotic resistance in water supply systems in a small town in Mozambique"],"prefix":"10.1186","volume":"22","author":[{"given":"Elisa","family":"Taviani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"van den Berg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Nhassengo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenia","family":"Nguluve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jussa","family":"Paulo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Pedro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliana","family":"Ferrero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,10,8]]},"reference":[{"key":"2654_CR1","unstructured":"UN. 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