{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T01:23:25Z","timestamp":1789608205804,"version":"build-2803163510"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T00:00:00Z","timestamp":1726876800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T00:00:00Z","timestamp":1726876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Microbiol"],"DOI":"10.1186\/s12866-024-03495-y","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T00:01:41Z","timestamp":1726876901000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effectiveness of selective antibiotics use in ESBL-related UTIs"],"prefix":"10.1186","volume":"24","author":[{"given":"Aththanayaka Mudiyanselage Waththe","family":"Aththanayaka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gangulwitiya Gamage Yasodha Hansani","family":"Weerasinghe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimsha Sevwandika","family":"Weerakkody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samarasinghe Herathge Gayani Geethi","family":"Samarasinghe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Upul","family":"Priyadharshana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,9,21]]},"reference":[{"key":"3495_CR1","doi-asserted-by":"publisher","unstructured":"Yadav K, Prakash S. Screening of ESBL Producing Multidrug Resistant E. Coli from urinary tract infection suspected cases in Southern Terai of Nepal. J Infect Dis Diagnosis. 2017;02(02). https:\/\/doi.org\/10.4172\/2576-389x.1000116.","DOI":"10.4172\/2576-389x.1000116"},{"key":"3495_CR2","doi-asserted-by":"publisher","unstructured":"Tula A, Mikru A, Alemayehu T, Dobo B. Bacterial Profile and Antibiotic susceptibility pattern of urinary tract infection among pregnant women attending Antenatal Care at a Tertiary Care Hospital in Southern Ethiopia. Can J Infect Dis Med Microbiol. 2020;2020. https:\/\/doi.org\/10.1155\/2020\/5321276.","DOI":"10.1155\/2020\/5321276"},{"issue":"1","key":"3495_CR3","doi-asserted-by":"publisher","first-page":"28","DOI":"10.3126\/jmcjms.v2i1.11393","volume":"2","author":"K Yadav","year":"2014","unstructured":"Yadav K, Prakash S, Serayi R, Shilpkar T, Shrestha S. Antimicrobial susceptibility test of pathogens isolated from urinary tract infection suspected cases. Janaki Med Coll J Med Sci. 2014;2(1):28\u201334. https:\/\/doi.org\/10.3126\/jmcjms.v2i1.11393.","journal-title":"Janaki Med Coll J Med Sci"},{"key":"3495_CR4","unstructured":"Care P. Resistance to Mecillinam and Nine other antibiotics for oral use in Escherichia coli isolated from urine specimens of, 2022."},{"key":"3495_CR5","doi-asserted-by":"publisher","unstructured":"Priyadharshana U, Piyasiri LB, Wijesinghe C. Prevalence, antibiotic sensitivity pattern and genetic analysis of extended-spectrum beta-lactamase producing Escherichia coli and Klebsiella spp among patients with community acquired urinary tract infection in Galle district, Sri Lanka. Ceylon Med J. Dec. 2019;64(4):140. https:\/\/doi.org\/10.4038\/cmj.v64i4.8990.","DOI":"10.4038\/cmj.v64i4.8990"},{"key":"3495_CR6","doi-asserted-by":"publisher","unstructured":"FME, Wagenlehner U, Hoyme M, Kaase R, F\u00fcnfst\u00fcck KG, Naber, Schmiemann G. Unkomplizierte Harnwegsinfektionen. Dtsch Arztebl. 2011;108(24):415\u201323. https:\/\/doi.org\/10.3238\/arztebl.2011.0415.","DOI":"10.3238\/arztebl.2011.0415"},{"issue":"1","key":"3495_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12879-022-07040-y","volume":"22","author":"H Liu","year":"2022","unstructured":"Liu H, Qiu S, Chen M, Lyu J, Yu G, Xue L. A clinical prediction tool for extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae urinary tract infection. BMC Infect Dis. 2022;22(1):1\u201313. https:\/\/doi.org\/10.1186\/s12879-022-07040-y.","journal-title":"BMC Infect Dis"},{"issue":"5","key":"3495_CR8","doi-asserted-by":"publisher","first-page":"2137","DOI":"10.1128\/AAC.49.5.2137-2139.2005","volume":"49","author":"MJ Schwaber","year":"2005","unstructured":"Schwaber MJ, Navon-Venezia S, Schwartz D, Carmeli Y. High levels of antimicrobial coresistance among extended-spectrum-\u03b2- lactamase-producing Enterobacteriaceae. Antimicrob Agents Chemother. 2005;49(5):2137\u20139. https:\/\/doi.org\/10.1128\/AAC.49.5.2137-2139.2005.","journal-title":"Antimicrob Agents Chemother"},{"key":"3495_CR9","doi-asserted-by":"crossref","unstructured":"Aboumarzouk OM. Extended spectrum beta \u2013 lactamase urinary tract infections, 6, 2, pp. 2012\u20133, 2014.","DOI":"10.4103\/0974-7796.130550"},{"key":"3495_CR10","doi-asserted-by":"publisher","unstructured":"Naushad VA et al. Epidemiology of urinary tract infection in adults caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae \u2013 a case\u2013control study from Qatar, IJID Reg., vol. 3, no. May, pp. 278\u2013286, 2022, https:\/\/doi.org\/10.1016\/j.ijregi.2022.05.001","DOI":"10.1016\/j.ijregi.2022.05.001"},{"key":"3495_CR11","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1038\/nrmicro3432.Urinary","volume":"13","author":"VJ Mandracchia","year":"2016","unstructured":"Mandracchia VJ, Hayes DW, Yoho RM, Hayes MF. Diagnosis, Differential and Treatment options. Nat Rev Microbiol. 2016;13:34. https:\/\/doi.org\/10.1038\/nrmicro3432.Urinary.","journal-title":"Nat Rev Microbiol"},{"key":"3495_CR12","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1093\/jtm\/taw102","volume":"24","author":"Y Doi","year":"2017","unstructured":"Doi Y, Iovleva A, Bonomo RA. The ecology of extended-spectrum b-lactamases (ESBLs) in the developed world. J Travel Med. 2017;24:44\u201351. https:\/\/doi.org\/10.1093\/jtm\/taw102.","journal-title":"J Travel Med"},{"issue":"11","key":"3495_CR13","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.4103\/ijmr.IJMR","volume":"76","author":"A Aggarwal","year":"2012","unstructured":"Aggarwal A, et al. Clinical & immunological erythematosus patients characteristics in systemic lupus Maryam. J Dent Educ. 2012;76(11):1532\u20139. https:\/\/doi.org\/10.4103\/ijmr.IJMR.","journal-title":"J Dent Educ"},{"issue":"1","key":"3495_CR14","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1002\/jor.23656","volume":"36","author":"B Li","year":"2018","unstructured":"Li B, Webster TJ. Bacteria antibiotic resistance: new challenges and opportunities for implant-associated orthopedic infections. J Orthop Res. 2018;36(1):22\u201332. https:\/\/doi.org\/10.1002\/jor.23656.","journal-title":"J Orthop Res"},{"key":"3495_CR15","doi-asserted-by":"publisher","unstructured":"Bryce A, Hay AD, Lane IF, Thornton HV, Wootton M, Costelloe C. Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: Systematic review and meta-analysis, BMJ (Online), vol. 352. BMJ Publishing Group, Mar. 15, 2016. https:\/\/doi.org\/10.1136\/bmj.i939","DOI":"10.1136\/bmj.i939"},{"issue":"1","key":"3495_CR16","doi-asserted-by":"publisher","first-page":"23","DOI":"10.2174\/1874285801711010023","volume":"11","author":"P Shakya","year":"2017","unstructured":"Shakya P, Shrestha D, Maharjan E, Sharma VK, Paudyal R. ESBL Production among E. Coli and Klebsiella spp. Causing urinary tract infection: a Hospital based study. Open Microbiol J. 2017;11(1):23\u201330. https:\/\/doi.org\/10.2174\/1874285801711010023.","journal-title":"Open Microbiol J"},{"issue":"1","key":"3495_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-020-79791-0","volume":"11","author":"MJ Gharavi","year":"2021","unstructured":"Gharavi MJ, Zarei J, Roshani-Asl P, Yazdanyar Z, Sharif M, Rashidi N. Comprehensive study of antimicrobial susceptibility pattern and extended spectrum beta-lactamase (ESBL) prevalence in bacteria isolated from urine samples. Sci Rep. 2021;11(1):1\u201311. https:\/\/doi.org\/10.1038\/s41598-020-79791-0.","journal-title":"Sci Rep"},{"issue":"1","key":"3495_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.29252\/jcbr.2.1.1","volume":"2","author":"VV Nanoty","year":"2018","unstructured":"Nanoty VV, Agrawal GN, Tankhiwale SS. Evaluation of Antibiotic Resistance and \u03b2- lactamase production in clinical isolates from a Tertiary Care Hospital in Central India. J Clin Basic Res. 2018;2(1):1\u20135. https:\/\/doi.org\/10.29252\/jcbr.2.1.1.","journal-title":"J Clin Basic Res"},{"issue":"1","key":"3495_CR19","first-page":"107","volume":"11","author":"OI Falodun","year":"2018","unstructured":"Falodun OI, Morakinyo YM, Fagade OE. Determination of water quality and detection of Extended Spectrum Beta-Lactamase producing Gram-negative bacteria in selected rivers located in Ibadan, Nigeria. Jordan J Biol Sci. 2018;11(1):107\u201312.","journal-title":"Jordan J Biol Sci"},{"issue":"2","key":"3495_CR20","doi-asserted-by":"publisher","first-page":"540","DOI":"10.12669\/pjms.292.3144","volume":"29","author":"MA Habeeb","year":"2013","unstructured":"Habeeb MA, Sarwar Y, Ali A, Salman M, Haque A. Rapid emergence of ESBL producers in E. Coli causing urinary and wound infections in Pakistan. Pakistan J Med Sci. 2013;29(2):540\u20134. https:\/\/doi.org\/10.12669\/pjms.292.3144.","journal-title":"Pakistan J Med Sci"},{"issue":"3","key":"3495_CR21","doi-asserted-by":"publisher","first-page":"449","DOI":"10.7860\/JCDR\/2013\/4990.2796","volume":"7","author":"M Mukherjee","year":"2013","unstructured":"Mukherjee M, Basu S, MuKherjee SKM, Majumder M. Multidrug-resistance and extended spectrum beta-lactamase production in uropathogenic E. Coli which were isolated from hospitalized patients in Kolkata, India. J Clin Diagn Res. 2013;7(3):449\u201353. https:\/\/doi.org\/10.7860\/JCDR\/2013\/4990.2796.","journal-title":"J Clin Diagn Res"},{"key":"3495_CR22","doi-asserted-by":"publisher","unstructured":"Dissanayake D, Fernando S, Chandrasiri N. The distribution and characteristics of extended-spectrum \u03b2-Lactamase producing Escherichia coli and Klebsiella species among urinary isolates in a tertiary care hospital. Sri Lankan J Infect Dis. Aug. 2012;2(2):30. https:\/\/doi.org\/10.4038\/sljid.v2i2.4235.","DOI":"10.4038\/sljid.v2i2.4235"},{"issue":"3","key":"3495_CR23","doi-asserted-by":"publisher","first-page":"160","DOI":"10.3947\/ic.2016.48.3.160","volume":"48","author":"LG Tillekeratne","year":"2016","unstructured":"Tillekeratne LG, et al. Extended-spectrum \u03b2-lactamase-producing Enterobacteriaceae as a common cause of urinary tract infections in Sri Lanka. Infect Chemother. 2016;48(3):160\u20135. https:\/\/doi.org\/10.3947\/ic.2016.48.3.160.","journal-title":"Infect Chemother"},{"key":"3495_CR24","doi-asserted-by":"publisher","unstructured":"CDC. Antibiotic Resistance Threats in The United States 2019, Cdc, vol. 10, no. 1, 2019, https:\/\/doi.org\/10.1186\/s13756-020-00872-w","DOI":"10.1186\/s13756-020-00872-w"},{"key":"3495_CR25","unstructured":"Ontario P. Trends in the rates of extended-Spectrum- b -Lactamase-producing enterobacterales isolated from urine cultures during the COVID-19, 2021."},{"issue":"1","key":"3495_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13756-021-00983-y","volume":"10","author":"E Raphael","year":"2021","unstructured":"Raphael E, Glymour MM, Chambers HF. Trends in prevalence of extended-spectrum beta-lactamase-producing Escherichia coli isolated from patients with community- and healthcare-associated bacteriuria: results from 2014 to 2020 in an urban safety-net healthcare system. Antimicrob Resist Infect Control. 2021;10(1):1\u201313. https:\/\/doi.org\/10.1186\/s13756-021-00983-y.","journal-title":"Antimicrob Resist Infect Control"},{"key":"3495_CR27","doi-asserted-by":"crossref","unstructured":"Wijesooriya W, Herath YB, Sugandhi RAI. Antibiotic sensitivity pattern for non-beta lactam antibiotics and carbapenems in extended-spectrum beta-lactamase (ESBL) producing uropathogens versus non- ESBL producing uropathogens, no. October, pp. 92\u201399, 2017.","DOI":"10.4038\/sljid.v7i2.8154"},{"issue":"2","key":"3495_CR28","doi-asserted-by":"publisher","first-page":"282","DOI":"10.4103\/0255-0857.153563","volume":"33","author":"B Nandagopal","year":"2015","unstructured":"Nandagopal B, et al. Frequency of extended spectrum \u03b2-lactamase producing urinary isolates of Gram-negative bacilli among patients seen in a multispecialty hospital in Vellore district, India. Indian J Med Microbiol. 2015;33(2):282\u20135. https:\/\/doi.org\/10.4103\/0255-0857.153563.","journal-title":"Indian J Med Microbiol"},{"key":"3495_CR29","doi-asserted-by":"publisher","unstructured":"Chander A, Shrestha CD. Prevalence of extended spectrum beta lactamase producing Escherichia coli and Klebsiella pneumoniae urinary isolates in a tertiary care hospital in Kathmandu, Nepal. BMC Res Notes. 2013;6(1). https:\/\/doi.org\/10.1186\/1756-0500-6-487.","DOI":"10.1186\/1756-0500-6-487"},{"issue":"6","key":"3495_CR30","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.jiph.2019.05.012","volume":"12","author":"NS Raja","year":"2019","unstructured":"Raja NS. Oral treatment options for patients with urinary tract infections caused by extended spectrum \u03b2eta-lactamase (ESBL) producing Enterobacteriaceae. J Infect Public Health. 2019;12(6):843\u20136. https:\/\/doi.org\/10.1016\/j.jiph.2019.05.012.","journal-title":"J Infect Public Health"},{"issue":"2","key":"3495_CR31","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3329\/dmcj.v5i2.33342","volume":"5","author":"N Akhtar","year":"2017","unstructured":"Akhtar N, Rahman R, Sultana S, Rahman MR. Antimicrobial Sensitivity Pattern of Bacterial Pathogens Associated with urinary tract infection. Delta Med Coll J. 2017;5(2):57\u201362. https:\/\/doi.org\/10.3329\/dmcj.v5i2.33342.","journal-title":"Delta Med Coll J"},{"issue":"5","key":"3495_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.28982\/josam.726628","volume":"6","author":"H HAKKOYMAZ","year":"2022","unstructured":"HAKKOYMAZ H. The assessment of etiology and risk factors of urinary tract infections in geriatric patients admitted to emergency department. J Surg Med. 2022;6(5):1\u20131. https:\/\/doi.org\/10.28982\/josam.726628.","journal-title":"J Surg Med"},{"key":"3495_CR33","doi-asserted-by":"crossref","unstructured":"Brumfitt W. Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years\u2019 experience, pp. 363\u201371, 1998.","DOI":"10.1093\/jac\/42.3.363"},{"key":"3495_CR34","doi-asserted-by":"publisher","unstructured":"Shilpakar A, Ansari M, Rai KR, Rai G, Rai SK. Prevalence of multidrug-resistant and extended-spectrum beta-lactamase producing Gram-negative isolates from clinical samples in a tertiary care hospital of Nepal. Trop Med Health. 2021;49(1). https:\/\/doi.org\/10.1186\/s41182-021-00313-3.","DOI":"10.1186\/s41182-021-00313-3"},{"issue":"5","key":"3495_CR35","doi-asserted-by":"publisher","first-page":"662","DOI":"10.18502\/ijm.v14i5.10959","volume":"14","author":"36Kaleem","year":"2022","unstructured":"36Kaleem. Reviving the role of mecillinam against extended spectrum beta-lactamase producing enterobacterales. Iran J Microbiol vol. 2022;14(5):662\u20138. https:\/\/doi.org\/10.18502\/ijm.v14i5.10959.","journal-title":"Iran J Microbiol vol"},{"key":"3495_CR36","doi-asserted-by":"publisher","unstructured":"Kresken M, Pfeifer Y, Wagenlehner F, Werner G, Wohlfarth E. Jun., Resistance to Mecillinam and Nine other antibiotics for oral use in Escherichia coli isolated from urine specimens of primary care patients in Germany, 2019\/20, Antibiotics, 11, 6, 2022, https:\/\/doi.org\/10.3390\/antibiotics11060751","DOI":"10.3390\/antibiotics11060751"}],"container-title":["BMC Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12866-024-03495-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12866-024-03495-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12866-024-03495-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T12:02:06Z","timestamp":1726920126000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcmicrobiol.biomedcentral.com\/articles\/10.1186\/s12866-024-03495-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,21]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3495"],"URL":"https:\/\/doi.org\/10.1186\/s12866-024-03495-y","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-4535041\/v1","asserted-by":"object"}]},"ISSN":["1471-2180"],"issn-type":[{"value":"1471-2180","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,21]]},"assertion":[{"value":"5 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the Ethical Review Committee of the Teaching Hospital, Polonnaruwa (DGHP\/ERC\/2023\/01). A letter of authorization was obtained from Teaching hospital, Polonnaruwa before data collection. All participants involved in the study have voluntarily agreed to participate and understand the nature, purpose, and potential risks of the research.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"360"}}