{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T01:06:45Z","timestamp":1793322405964,"version":"4.5.0"},"reference-count":68,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":44,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Microbiol"],"DOI":"10.1186\/s12866-025-04675-0","type":"journal-article","created":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T04:24:17Z","timestamp":1768623857000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Influence of polyunsaturated fatty acids on Aeromonas hydrophila: sole carbon utilization, incorporation into membrane phospholipids, potentiation of cyclic lipopeptide activity, and other phenotypic impacts"],"prefix":"10.1186","volume":"26","author":[{"given":"Meredith A.","family":"Grant","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia D.","family":"Byerly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian L. I.","family":"Morton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina R.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie F.","family":"Catlett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven J. K.","family":"Symes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David K.","family":"Giles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,17]]},"reference":[{"key":"4675_CR1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00039-09","author":"JM Janda","year":"2010","unstructured":"Janda JM, Abbott SL. The genus Aeromonas: taxonomy, pathogenicity, and infection. Clin Microbiol Rev. 2010. https:\/\/doi.org\/10.1128\/CMR.00039-09.","journal-title":"Clin Microbiol Rev"},{"key":"4675_CR2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.43-3-302","author":"S Monette","year":"2006","unstructured":"Monette S, Dallaire AD, Mingelbier M, et al. Massive mortality of common carp (Cyprinus carpio carpio) in the St. Lawrence River in 2001: diagnostic investigation and experimental induction of lymphocytic encephalitis. Vet Pathol. 2006. https:\/\/doi.org\/10.1354\/vp.43-3-302.","journal-title":"Vet Pathol"},{"key":"4675_CR3","doi-asserted-by":"publisher","DOI":"10.4194\/2459-1831-v3_1_03","author":"A Elsheshtawy","year":"2019","unstructured":"Elsheshtawy A, Yehia N, Elkemary M, Soliman H. Investigation of Nile tilapia summer mortality in Kafr El-Sheikh governorate, Egypt. Gen Aquat Org. 2019. https:\/\/doi.org\/10.4194\/2459-1831-v3_1_03.","journal-title":"Gen Aquat Org"},{"key":"4675_CR4","first-page":"151","volume-title":"The genus Aeromonas","author":"JM Janda","year":"1996","unstructured":"Janda JM, Abbott SL. Human pathogens. In: Austin B, Altwegg M, Gosling PJ, Joseph S, editors. The genus Aeromonas. West Sussex, England: John Wiley & Sons Ltd.; 1996. pp. 151\u201373. In."},{"key":"4675_CR5","doi-asserted-by":"crossref","unstructured":"El-Hossary D, Mahdy A, Elariny EY, Askora A, Merwad AMA, Saber T, Dahshan H, Hakami NY, Ibrahim RA. Antibiotic resistance, virulence gene detection, and biofilm formation in Aeromonas spp. Isolated from fish and humans in Egypt. Biology. 2023. 10.3390.biology12030421.","DOI":"10.3390\/biology12030421"},{"key":"4675_CR6","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.000556","author":"AE Eder","year":"2017","unstructured":"Eder AE, Munir SA, Hobby CR, et al. Exogenous polyunsaturated fatty acids (PUFAs) alter phospholipid composition, membrane permeability, biofilm formation and motility in Acinetobacter baumannii. Microbiology Reading. 2017. https:\/\/doi.org\/10.1099\/mic.0.000556.","journal-title":"Microbiology Reading"},{"key":"4675_CR7","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01415-17","author":"AR Moravec","year":"2017","unstructured":"Moravec AR, Siv AW, Hobby CR, et al. Exogenous polyunsaturated fatty acids impact membrane remodeling and affect virulence phenotypes among pathogenic Vibrio species. Appl Environ Microbiol. 2017. https:\/\/doi.org\/10.1128\/AEM.01415-17.","journal-title":"Appl Environ Microbiol"},{"key":"4675_CR8","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-018-1259-8","author":"LY Baker","year":"2018","unstructured":"Baker LY, Hobby CR, Siv AW, et al. Pseudomonas aeruginosa responds to exogenous polyunsaturated fatty acids (PUFAs) by modifying phospholipid composition, membrane permeability, and phenotypes associated with virulence. BMC Microbiol. 2018. https:\/\/doi.org\/10.1186\/s12866-018-1259-8.","journal-title":"BMC Microbiol"},{"key":"4675_CR9","doi-asserted-by":"publisher","DOI":"10.1002\/mbo3.635","author":"CR Hobby","year":"2019","unstructured":"Hobby CR, Herndon JL, Morrow CA, Peters RE, Symes SJK, Giles DK. Exogenous fatty acids alter phospholipid composition, membrane permeability, capacity for biofilm formation, and antimicrobial peptide susceptibility in Klebsiella pneumoniae. Microbiologyopen. 2019. https:\/\/doi.org\/10.1002\/mbo3.635.","journal-title":"Microbiologyopen"},{"key":"4675_CR10","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-020-01988-0","author":"JL Herndon","year":"2020","unstructured":"Herndon JL, Peters RE, Hofer RN, Simmons TB, Symes SJ, Giles DK. Exogenous polyunsaturated fatty acids (PUFAs) promote changes in growth, phospholipid composition, membrane permeability and virulence phenotypes in Escherichia coli. BMC Microbiol. 2020. https:\/\/doi.org\/10.1186\/s12866-020-01988-0.","journal-title":"BMC Microbiol"},{"key":"4675_CR11","doi-asserted-by":"publisher","DOI":"10.1002\/mbo3.1237","author":"DS Smith","year":"2021","unstructured":"Smith DS, Houck C, Lee A, et al. Polyunsaturated fatty acids cause physiological and behavioral changes in Vibrio alginolyticus and Vibrio fischeri. Microbiologyopen. 2021. https:\/\/doi.org\/10.1002\/mbo3.1237.","journal-title":"Microbiologyopen"},{"key":"4675_CR12","doi-asserted-by":"publisher","DOI":"10.1111\/jfd.13715","author":"RN Hofer","year":"2023","unstructured":"Hofer RN, Lin A, House BC, et al. Exogenous polyunsaturated fatty acids (PUFAs) influence permeability, antimicrobial peptide resistance, biofilm formation and membrane phospholipid structure in an A-layer and non-A-layer strain of Aeromonas salmonicida. J Fish Dis. 2023. https:\/\/doi.org\/10.1111\/jfd.13715.","journal-title":"J Fish Dis"},{"key":"4675_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2023.101504","author":"S Saksena","year":"2023","unstructured":"Saksena S, Forbes K, Rajan N, Giles D. Phylogenetic investigation of Gammaproteobacteria proteins involved in exogenous long-chain fatty acid acquisition and assimilation. Biochem Biophys Rep. 2023. https:\/\/doi.org\/10.1016\/j.bbrep.2023.101504.","journal-title":"Biochem Biophys Rep"},{"key":"4675_CR14","doi-asserted-by":"publisher","DOI":"10.1128\/aem.36.5.731-738.1978","author":"TC Hazen","year":"1978","unstructured":"Hazen TC, Fliermans CB, Hirsch RP, Esch GW. Prevalence and distribution of Aeromonas hydrophila in the United States. Appl Environ Microbiol. 1978. https:\/\/doi.org\/10.1128\/aem.36.5.731-738.1978.","journal-title":"Appl Environ Microbiol"},{"key":"4675_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2010.12.003","author":"JL Parker","year":"2011","unstructured":"Parker JL, Shaw JG. Aeromonas spp. clinical microbiology and disease. J Infect. 2011. https:\/\/doi.org\/10.1016\/j.jinf.2010.12.003.","journal-title":"J Infect"},{"key":"4675_CR16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0609359104","author":"RP Alexander","year":"2007","unstructured":"Alexander RP, Zhulin IB. Evolutionary genomics reveals conserved structural determinants of signaling and adaptation in microbial chemoreceptors. Proc Natl Acad Sci U S A. 2007. https:\/\/doi.org\/10.1073\/pnas.0609359104.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"4675_CR17","unstructured":"Miller JH. Experiments in molecular genetics. Cold Spring Harbor Laboratory; 1972."},{"key":"4675_CR18","doi-asserted-by":"publisher","DOI":"10.1139\/o59-099","author":"EG Bligh","year":"1957","unstructured":"Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1957. https:\/\/doi.org\/10.1139\/o59-099.","journal-title":"Can J Biochem Physiol"},{"issue":"10","key":"4675_CR19","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1016\/S1044-0305(00)00159-8","volume":"11","author":"FF Hsu","year":"2000","unstructured":"Hsu FF, Turk J. Charge-remote and charge-driven fragmentation processes in diacyl glycerophosphoethanolamine upon low-energy collisional activation: a mechanistic proposal. J Am Soc Mass Spectrom. 2000;11(10):892\u20139. https:\/\/doi.org\/10.1016\/S1044-0305(00)00159-8.","journal-title":"J Am Soc Mass Spectrom"},{"issue":"11","key":"4675_CR20","doi-asserted-by":"publisher","first-page":"1721","DOI":"10.1002\/rcm.3013","volume":"21","author":"D Oursel","year":"2007","unstructured":"Oursel D, Loutelier-Bourhis C, Orange N, Chevalier S, Norris V, Lange CM. Lipid composition of membranes of Escherichia coli by liquid chromatography\/tandem mass spectrometry using negative electrospray ionization. Rapid Commun Mass Spectrom. 2007;21(11):1721\u20138. https:\/\/doi.org\/10.1002\/rcm.3013.","journal-title":"Rapid Commun Mass Spectrom"},{"key":"4675_CR21","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2007.521","author":"I Wiegand","year":"2008","unstructured":"Wiegand I, Hilpert K, Hancock RE. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc. 2008. https:\/\/doi.org\/10.1038\/nprot.2007.521.","journal-title":"Nat Protoc"},{"issue":"2","key":"4675_CR22","doi-asserted-by":"publisher","DOI":"10.3390\/biom8020029","volume":"8","author":"EF Haney","year":"2018","unstructured":"Haney EF, Trimble MJ, Cheng JT, Vall\u00e9 Q, Hancock REW. Critical assessment of methods to quantify biofilm growth and evaluate antibiofilm activity of host defence peptides. Biomolecules. 2018;8(2):29. https:\/\/doi.org\/10.3390\/biom8020029.","journal-title":"Biomolecules"},{"issue":"10","key":"4675_CR23","doi-asserted-by":"publisher","DOI":"10.21769\/BioProtoc.3237.","volume":"9","author":"X Shao","year":"2019","unstructured":"Shao X, Xie Y, Zhang Y, Deng X. Biofilm formation assay in Pseudomonas syringae. Bio-protocol. 2019;9(10):e3237. https:\/\/doi.org\/10.21769\/BioProtoc.3237.","journal-title":"Bio-protocol"},{"key":"4675_CR24","doi-asserted-by":"publisher","unstructured":"Dias C, Mota V, Martinez-Murcia A, Saavedra MJ. Antimicrobial resistance patterns of Aeromonas spp. Isolated from ornamental fish. J Aquacult Res Dev. 2012;3(3). https:\/\/doi.org\/10.4172\/2155-9546.1000131.","DOI":"10.4172\/2155-9546.1000131"},{"issue":"2","key":"4675_CR25","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1111\/j.1365-2672.1981.tb00900.x","volume":"50","author":"JB Kaper","year":"1981","unstructured":"Kaper JB, Lockman H, Colwell RR, Joseph SW. Aeromonas hydrophila: ecology and toxigenicity of isolates from an estuary. J Appl Bacteriol. 1981;50(2):359\u201377. https:\/\/doi.org\/10.1111\/j.1365-2672.1981.tb00900.x.","journal-title":"J Appl Bacteriol"},{"issue":"1","key":"4675_CR26","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1128\/jb.161.1.463-465.1985","volume":"161","author":"SP Howard","year":"1985","unstructured":"Howard SP, Buckley JT. Phospholipids and lipopolysaccharide of Aeromonas hydrophila. J Bacteriol. 1985;161(1):463\u20135. https:\/\/doi.org\/10.1128\/jb.161.1.463-465.1985.","journal-title":"J Bacteriol"},{"issue":"1","key":"4675_CR27","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0378-1097(03)00418-X","volume":"224","author":"R Gav\u00edn","year":"2003","unstructured":"Gav\u00edn R, Merino S, Altarriba M, Canals R, Shaw JG, Tom\u00e1s JM. Lateral flagella are required for increased cell adherence, invasion and biofilm formation by Aeromonas spp. FEMS Microbiol Lett. 2003;224(1):77\u201383. https:\/\/doi.org\/10.1016\/S0378-1097(03)00418-X.","journal-title":"FEMS Microbiol Lett"},{"issue":"5\u20136","key":"4675_CR28","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.micpath.2008.08.007","volume":"45","author":"EV Kozlova","year":"2008","unstructured":"Kozlova EV, Popov VL, Sha J, et al. Mutation in the S-ribosylhomocysteinase (luxS) gene involved in quorum sensing affects biofilm formation and virulence in a clinical isolate of Aeromonas hydrophila. Microb Pathog. 2008;45(5\u20136):343\u201354. https:\/\/doi.org\/10.1016\/j.micpath.2008.08.007.","journal-title":"Microb Pathog"},{"issue":"1","key":"4675_CR29","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1046\/j.1462-2920.2002.00264.x","volume":"4","author":"MJ Lynch","year":"2002","unstructured":"Lynch MJ, Swift S, Kirke DF, Keevil CW, Dodd CE, Williams P. The regulation of biofilm development by quorum sensing in Aeromonas hydrophila. Environ Microbiol. 2002;4(1):18\u201328. https:\/\/doi.org\/10.1046\/j.1462-2920.2002.00264.x.","journal-title":"Environ Microbiol"},{"issue":"3","key":"4675_CR30","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/0732-8893(85)90034-3","volume":"3","author":"JM Janda","year":"1985","unstructured":"Janda JM. Biochemical and exoenzymatic properties of Aeromonas species. Diagn Microbiol Infect Dis. 1985;3(3):223\u201332. https:\/\/doi.org\/10.1016\/0732-8893(85)90034-3.","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"1","key":"4675_CR31","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.femsle.2004.10.011","volume":"241","author":"DF Kirke","year":"2004","unstructured":"Kirke DF, Swift S, Lynch MJ, Williams P. The Aeromonas hydrophila LuxR homologue AhyR regulates the N-acyl Homoserine lactone synthase, AhyI positively and negatively in a growth phase-dependent manner. FEMS Microbiol Lett. 2004;241(1):109\u201317. https:\/\/doi.org\/10.1016\/j.femsle.2004.10.011.","journal-title":"FEMS Microbiol Lett"},{"issue":"4","key":"4675_CR32","doi-asserted-by":"publisher","first-page":"1939","DOI":"10.1128\/IAI.72.4.1939-1945.2004","volume":"72","author":"SM Kirov","year":"2004","unstructured":"Kirov SM, Castrisios M, Shaw JG. Aeromonas flagella (polar and lateral) are enterocyte adhesins that contribute to biofilm formation on surfaces. Infect Immun. 2004;72(4):1939\u201345. https:\/\/doi.org\/10.1128\/IAI.72.4.1939-1945.2004.","journal-title":"Infect Immun"},{"key":"4675_CR33","doi-asserted-by":"crossref","unstructured":"Huo LC, Liu NY, Wang CJ. <Emphasis Type=\"Italic\">et al. Lonicera japonica<\/Emphasis> protects <Emphasis Type=\"Italic\">Pelodiscus sinensis<\/Emphasis> by inhibiting the biofilm formation of <Emphasis Type=\"Italic\">Aeromonas hydrophila<\/Emphasis>. Appl Microbiol Biotechnol. 2024;108:67.","DOI":"10.1007\/s00253-023-12910-9"},{"issue":"Pt 1","key":"4675_CR34","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1099\/mic.0.051805-0","volume":"158","author":"BK Khajanchi","year":"2012","unstructured":"Khajanchi BK, Kozlova EV, Sha J, Popov VL, Chopra AK. The two-component QseBC signaling system regulates in vitro and in vivo virulence of Aeromonas hydrophila. Microbiology (Reading). 2012;158(Pt 1):259\u201371. https:\/\/doi.org\/10.1099\/mic.0.051805-0.","journal-title":"Microbiology (Reading)"},{"key":"4675_CR35","doi-asserted-by":"publisher","unstructured":"Qin Y, Lin G, Chen W, Xu X. Qingpi Yan,Flagellar motility is necessary for Aeromonas hydrophila adhesion, microbial Pathogenesis,98,2016,Pages 160\u2013166,ISSN 0882\u20134010, https:\/\/doi.org\/10.1016\/j.micpath.2016.07.006.","DOI":"10.1016\/j.micpath.2016.07.006."},{"issue":"2","key":"4675_CR36","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.fsi.2014.05.016","volume":"39","author":"Y Qin","year":"2014","unstructured":"Qin Y, Lin G, Chen W, Huang B, Huang W, Yan Q. Flagellar motility contributes to the invasion and survival of Aeromonas hydrophila in Anguilla japonica macrophages. Fish Shellfish Immunol. 2014;39(2):273\u20139. https:\/\/doi.org\/10.1016\/j.fsi.2014.05.016.","journal-title":"Fish Shellfish Immunol"},{"key":"4675_CR37","doi-asserted-by":"publisher","unstructured":"Tha. Thayumanavan G, Vivekanandhan K, Savithamani R, Subashkumar P, Lakshmanaperumalsamy. Incidence of haemolysin-positive and drug-resistant Aeromonas hydrophila in freshly caught finfish and Prawn collected from major commercial fishes of coastal South India. FEMS Immunol Med Microbiol. May 2003;36(1\u20132):41\u20135. https:\/\/doi.org\/10.1016\/S0928-8244(03)00037-3.","DOI":"10.1016\/S0928-8244(03)00037-3."},{"key":"4675_CR38","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01875","volume":"7","author":"HJ Patil","year":"2016","unstructured":"Patil HJ, Benet-Perelberg A, Naor A, et al. Evidence of increased antibiotic resistance in phylogenetically-diverse Aeromonas isolates from semi-intensive fish ponds treated with antibiotics. Front Microbiol. 2016;7:1875. https:\/\/doi.org\/10.3389\/fmicb.2016.01875.","journal-title":"Front Microbiol"},{"issue":"2","key":"4675_CR39","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1111\/lam.13489","volume":"73","author":"LADS De Silva","year":"2021","unstructured":"De Silva LADS, Wickramanayake MVKS, Heo GJ. Virulence and antimicrobial resistance potential of Aeromonas spp. associated with shellfish. Lett Appl Microbiol. 2021;73(2):176\u201386. https:\/\/doi.org\/10.1111\/lam.13489.","journal-title":"Lett Appl Microbiol"},{"issue":"1","key":"4675_CR40","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1111\/jam.14965]","volume":"131","author":"D Conte","year":"2021","unstructured":"Conte D, Palmeiro JK, Bavaroski AA, et al. Antimicrobial resistance in Aeromonas species isolated from aquatic environments in Brazil. J Appl Microbiol. 2021;131(1):169\u201381. https:\/\/doi.org\/10.1111\/jam.14965].","journal-title":"J Appl Microbiol"},{"key":"4675_CR41","doi-asserted-by":"publisher","unstructured":"Rouf MA, Rigney MM. Growth temperatures and temperature characteristics of Aeromonas. Appl Microbiol. 1971;22(4):503\u2013506.1971.https:\/\/doi.org\/10.1128\/am.22.4.503-506.1971","DOI":"10.1128\/am.22.4.503-506.1971"},{"issue":"2","key":"4675_CR42","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1128\/jcm.26.2.392-393.1988","volume":"26","author":"B Statner","year":"1988","unstructured":"Statner B, Jones MJ, George WL. Effect of incubation temperature on growth and soluble protein profiles of motile Aeromonas strains. J Clin Microbiol. 1988;26(2):392\u20133. https:\/\/doi.org\/10.1128\/jcm.26.2.392-393.1988.","journal-title":"J Clin Microbiol"},{"key":"4675_CR43","doi-asserted-by":"publisher","unstructured":"Committee on animal nutrition board on agriculture National Research Council: nutrient requirements of fish. 1st ed. Washington: National Academy Press, Tocher DR. Fatty acid requirements in ontogeny of marine and freshwater fish. Aquaculture Research, 2010, 41:717\u2013732. https:\/\/doi.org\/10.1111\/j.1365-2109.2008.02150.x","DOI":"10.1111\/j.1365-2109.2008.02150.x"},{"key":"4675_CR44","volume-title":"Fish nutrition","author":"JE Halver","year":"2002","unstructured":"Halver JE, Hardy RW. Fish nutrition. 3th ed. USA: Academic, Elsevier Science;; 2002.","edition":"3"},{"issue":"5","key":"4675_CR45","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1016\/j.bbapap.2008.11.005","volume":"1794","author":"AH Delcour","year":"2009","unstructured":"Delcour AH. Outer membrane permeability and antibiotic resistance. Biochim Biophys Acta. 2009;1794(5):808\u201316. https:\/\/doi.org\/10.1016\/j.bbapap.2008.11.005.","journal-title":"Biochim Biophys Acta"},{"issue":"4","key":"4675_CR46","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1128\/MMBR.67.4.593-656.2003","volume":"67","author":"H Nikaido","year":"2003","unstructured":"Nikaido H. Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biology Reviews: MMBR. 2003;67(4):593\u2013656. https:\/\/doi.org\/10.1128\/MMBR.67.4.593-656.2003.","journal-title":"Microbiol Mol Biology Reviews: MMBR"},{"issue":"3","key":"4675_CR47","doi-asserted-by":"publisher","first-page":"575","DOI":"10.4315\/0362-028x-65.3.575","volume":"65","author":"JH Isonhood","year":"2002","unstructured":"Isonhood JH, Drake M. Aeromonas species in foods. J Food Prot. 2002;65(3):575\u201382. https:\/\/doi.org\/10.4315\/0362-028x-65.3.575.","journal-title":"J Food Prot"},{"issue":"5","key":"4675_CR48","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1046\/j.1472-765x.2000.00828.x","volume":"31","author":"K Neyts","year":"2000","unstructured":"Neyts K, Huys G, Uyttendaele M, Swings J, Debevere J. Incidence and identification of mesophilic Aeromonas spp. from retail foods. Lett Appl Microbiol. 2000;31(5):359\u201363. https:\/\/doi.org\/10.1046\/j.1472-765x.2000.00828.x.","journal-title":"Lett Appl Microbiol"},{"key":"4675_CR49","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2023.113671","volume":"175","author":"M Ashikur Rahman","year":"2024","unstructured":"Ashikur Rahman M, Akter S, Ashrafudoulla M, et al. Insights into the mechanisms and key factors influencing biofilm formation by Aeromonas hydrophila in the food industry: a comprehensive review and bibliometric analysis. Food Res Int. 2024;175:113671. https:\/\/doi.org\/10.1016\/j.foodres.2023.113671.","journal-title":"Food Res Int"},{"key":"4675_CR50","doi-asserted-by":"publisher","DOI":"10.1007\/s10499-024-01535-y","author":"B Abdella","year":"2024","unstructured":"Abdella B, Shokrak NM, Abozahra NA, et al. Aquaculture and Aeromonas hydrophila: a complex interplay of environmental factors and virulence. Aquacult Int. 2024. https:\/\/doi.org\/10.1007\/s10499-024-01535-y.","journal-title":"Aquacult Int"},{"issue":"6","key":"4675_CR51","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.foodcont.2005.02.009","volume":"17","author":"Hristo Daskalov","year":"2006","unstructured":"Daskalov Hristo. The importance of Aeromonas hydrophila in food safety. Food Control. 2006;17(6):474\u201383. https:\/\/doi.org\/10.1016\/j.foodcont.2005.02.009.","journal-title":"Food Control"},{"issue":"3","key":"4675_CR52","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1080\/1040841X.2023.2186215","volume":"50","author":"C Chen","year":"2024","unstructured":"Chen C, Shi J, Wang D, Kong P, Wang Z, Liu Y. Antimicrobial peptides as promising antibiotic adjuvants to combat drug-resistant pathogens. Crit Rev Microbiol. 2024;50(3):267\u201384. https:\/\/doi.org\/10.1080\/1040841X.2023.2186215.","journal-title":"Crit Rev Microbiol"},{"issue":"Pt B","key":"4675_CR53","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.biochi.2023.07.016","volume":"214","author":"A Savitskaya","year":"2023","unstructured":"Savitskaya A, Masso-Silva J, Haddaoui I, Enany S. Exploring the arsenal of antimicrobial peptides: mechanisms, diversity, and applications. Biochimie. 2023;214(Pt B):216\u201327. https:\/\/doi.org\/10.1016\/j.biochi.2023.07.016.","journal-title":"Biochimie"},{"key":"4675_CR54","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2017.00073","volume":"11","author":"J Li","year":"2017","unstructured":"Li J, Koh J-J, Liu S, Lakshminarayanan R, Verma CS, Beuerman RW. Membrane active antimicrobial peptides: translating mechanistic insights to design. Front Neurosci. 2017;11:73. https:\/\/doi.org\/10.3389\/fnins.2017.00073.","journal-title":"Front Neurosci"},{"key":"4675_CR55","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-019-0297-6","volume":"2","author":"A Khondker","year":"2019","unstructured":"Khondker A, Dhaliwal AK, Saem S, Mahmood A, Fradin C, Moran-Mirabel J, et al. Membrane charge and lipid packing determine polymyxin-induced membrane damage. Commun Biol. 2019;2:67. https:\/\/doi.org\/10.1038\/s42003-019-0297-6.","journal-title":"Commun Biol"},{"issue":"4","key":"4675_CR56","doi-asserted-by":"publisher","first-page":"7030","DOI":"10.1074\/jbc.RA117.000705","volume":"293","author":"I Ghai","year":"2018","unstructured":"Ghai I, Bajaj H, Arun Bafna J, El Damrany Hussein HA, Winterhalter M, Wagner R. Ampicillin permeation across OmpF, the major outer-membrane channel in Escherichia coli. J Biol Chem. 2018;293(4):7030\u20137. https:\/\/doi.org\/10.1074\/jbc.RA117.000705.","journal-title":"J Biol Chem"},{"issue":"24","key":"4675_CR57","doi-asserted-by":"publisher","first-page":"7793","DOI":"10.1128\/jb.175.24.7793-7800.1993","volume":"175","author":"H Huang","year":"1993","unstructured":"Huang H, Hancock RE. Genetic definition of the substrate selectivity of outer membrane porin protein OprD of Pseudomonas aeruginosa. J Bacteriol. 1993;175(24):7793-7800.1993. https:\/\/doi.org\/10.1128\/jb.175.24.7793-7800.1993.","journal-title":"J Bacteriol"},{"issue":"3","key":"4675_CR58","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1111\/jfd.12516","volume":"40","author":"HY Chenia","year":"2017","unstructured":"Chenia HY, Duma S. Characterization of virulence, cell surface characteristics and biofilm-forming ability of Aeromonas spp. isolates from fish and sea water. J Fish Dis. 2017;40(3):339\u201350. https:\/\/doi.org\/10.1111\/jfd.12516.","journal-title":"J Fish Dis"},{"key":"4675_CR59","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2023.113671","volume":"175","author":"M Ashikur Rahman","year":"2024","unstructured":"Ashikur Rahman M, Akter S, Ashrafudoulla M, et al. Insights into the mechanisms and key factors influencing biofilm formation by Aeromonas hydrophila in the food industry: a comprehensive review and bibliometric analysis. Food Res Int. 2024;175:113671. https:\/\/doi.org\/10.1016\/j.foodres.2023.113671.","journal-title":"Food Res Int"},{"key":"4675_CR60","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2023.110316","volume":"404","author":"JM Dorick","year":"2023","unstructured":"Dorick JM, Macarisin D, Dunn L, Dev Kumar G. Effect of aquaponic water and substratum material on biofilm formation by Aeromonas hydrophila. Int J Food Microbiol. 2023;404:110316. https:\/\/doi.org\/10.1016\/j.ijfoodmicro.2023.110316.","journal-title":"Int J Food Microbiol"},{"key":"4675_CR61","doi-asserted-by":"publisher","unstructured":"Wenbin Wang Y, Cao J, Li S, Lu H, Ge S, Pan X, Pan L, Wang. The impact of osmotic stresses on the biofilm formation, immunodetection, and morphology of Aeromonas hydrophila, MicrobiologicalResearch,Volume269,2023,127301,ISSN0944\u20135013,https:\/\/doi.org\/10.1016\/j.micres.2023.127301","DOI":"10.1016\/j.micres.2023.127301"},{"key":"4675_CR62","unstructured":"MIZANa MFR, JAHIDa IK, b, PARKc SY, SILVAd JL, KIMe TJ, MYOUNG*f J, HA S-D. Effects of temperature on biofilm formation and quorum sensing of Aeromonas hydrophila. Ital. J. Food Sci., vol. 30, 2018."},{"key":"4675_CR63","doi-asserted-by":"publisher","unstructured":"Jais AMM, Matori MF, Kittakoop P. Khanit Sowanborirux. Fatty Acid Compositions in Mucus and Roe of Haruan, Channa Striatus, for Wound Healing, General Pharmacology: The Vascular System,Volume 30, Issue 4, 1998,Pages 561\u2013563,ISSN 0306\u20133623,https:\/\/doi.org\/10.1016\/S0306-3623(97)00305-4","DOI":"10.1016\/S0306-3623(97)00305-4"},{"key":"4675_CR64","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1007\/BF02530968","volume":"3","author":"BW Nichols","year":"1968","unstructured":"Nichols BW, Wood BJB. The occurrence and biosynthesis of gamma-linolenic acid in a blue-green alga,Spirulina platensis. Lipids. 1968;3:46\u201350. https:\/\/doi.org\/10.1007\/BF02530968.","journal-title":"Lipids"},{"key":"4675_CR65","doi-asserted-by":"publisher","DOI":"10.5772\/68048","volume-title":"Fatty Acids in Fish","author":"O Ta\u015fbozan","year":"2017","unstructured":"Ta\u015fbozan O, G\u00f6k\u00e7e MA. Fatty Acids in Fish. InTech; 2017. https:\/\/doi.org\/10.5772\/68048."},{"key":"4675_CR66","doi-asserted-by":"publisher","unstructured":"Hiroto Terashi K, Izumi LM, Rhodes CL. Marcelo,Human stratified squamous epithelia differ in cellular fatty acid composition. J Dermatol Sci, 24, Issue 1,2000,Pages 14\u201324,ISSN 0923\u20131811,https:\/\/doi.org\/10.1016\/S0923-1811(00)00077-3","DOI":"10.1016\/S0923-1811(00)00077-3"},{"issue":"3","key":"4675_CR67","doi-asserted-by":"publisher","first-page":"349","DOI":"10.5021\/ad.2019.31.3.349","volume":"31","author":"CM Lee","year":"2019","unstructured":"Lee CM, Jin SP, Doh EJ, Lee DH, Chung JH. Regional variation of human skin surface temperature. Ann Dermatol. 2019;31(3):349\u201352. https:\/\/doi.org\/10.5021\/ad.2019.31.3.349. Epub 2019 May 1. PMID: 33911607; PMCID: PMC7992731.","journal-title":"Ann Dermatol"},{"issue":"1","key":"4675_CR68","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3354\/dao03006","volume":"120","author":"S Menanteau-Ledouble","year":"2016","unstructured":"Menanteau-Ledouble S, Kumar G, Saleh M, El-Matbouli M. Aeromonas salmonicida: updates on an old acquaintance. Dis Aquat Organ. 2016;120(1):49\u201368. https:\/\/doi.org\/10.3354\/dao03006.","journal-title":"Dis Aquat Organ"}],"container-title":["BMC Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12866-025-04675-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12866-025-04675-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12866-025-04675-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T09:21:22Z","timestamp":1772443282000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12866-025-04675-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,17]]},"references-count":68,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4675"],"URL":"https:\/\/doi.org\/10.1186\/s12866-025-04675-0","relation":{},"ISSN":["1471-2180"],"issn-type":[{"value":"1471-2180","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,17]]},"assertion":[{"value":"7 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"176"}}