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Additionally, the study has been registered with the China Clinical Trials Registration Center (ChiCTR), bearing the unique registration number ChiCTR2400090750, with the registration date of October 12, 2024. This study was conducted and reported in accordance with the CONSORT 2025 guidelines for randomized controlled trials. All participants in clinical experiment also provided a signed written informed consent.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"188"}}