{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:03:42Z","timestamp":1789617822714,"version":"build-2803163510"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":40,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["32473097"],"award-info":[{"award-number":["32473097"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Microbiol"],"DOI":"10.1186\/s12866-026-04920-0","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T08:58:02Z","timestamp":1773910682000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Probiotic potential of Companilactobacillus alimentarius Y4 in alleviating ciprofloxacin-resistant Salmonella-induced intestinal inflammation through microbiota\u2013metabolite modulation"],"prefix":"10.1186","volume":"26","author":[{"given":"Tajin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengguang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingrui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingcong","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haipeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxia","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"4920_CR1","doi-asserted-by":"publisher","unstructured":"Intuy R, Supa-Amornkul S, Jaemsai B, Ruangchai W, Wiriyarat W, Chaturongakul S, et al. A novel variant inSalmonella genomic island 1 of multidrug-resistantSalmonella enterica serovar Kentucky ST198. MICROBIOL SPECTR. 2024;12(6). https:\/\/doi.org\/10.1128\/spectrum.03994-23.","DOI":"10.1128\/spectrum.03994-23"},{"issue":"3","key":"4920_CR2","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.pedneo.2013.01.010","volume":"54","author":"H Chen","year":"2013","unstructured":"Chen H, Wang Y, Su L, Chiu C. Nontyphoid Salmonella Infection: Microbiology, Clinical Features,and Antimicrobial Therapy. Pediatr Neonatology. 2013;54(3):147\u201352. https:\/\/doi.org\/10.1016\/j.pedneo.2013.01.010.","journal-title":"Pediatr Neonatology"},{"issue":"1","key":"4920_CR3","doi-asserted-by":"publisher","first-page":"76","DOI":"10.3390\/antibiotics13010076","volume":"13","author":"B Lamichhane","year":"2024","unstructured":"Lamichhane B, Mawad AMM, Saleh M, Kelley WG, Harrington PJ, et al. Salmonellosis: An Overview of Epidemiology, Pathogenesis, and Innovative Approaches to Mitigate the Antimicrobial Resistant Infections. Antibiotics. 2024;13(1):76. https:\/\/doi.org\/10.3390\/antibiotics13010076.","journal-title":"Antibiotics"},{"key":"4920_CR4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ijfoodmicro.2018.05.001","volume":"280","author":"D Kuang","year":"2018","unstructured":"Kuang D, Zhang J, Xu X, Shi W, Chen S, Yang X, et al. Emerging high-level ciprofloxacin resistance and molecular basis of resistance in Salmonella enterica from humans, food and animals. INT J FOOD MICROBIOL. 2018;280:1\u20139. https:\/\/doi.org\/10.1016\/j.ijfoodmicro.2018.05.001.","journal-title":"INT J FOOD MICROBIOL"},{"key":"4920_CR5","doi-asserted-by":"publisher","unstructured":"Cuypers WL, Jacobs J, Wong V, Klemm EJ, Deborggraeve S, Van Puyvelde S. Fluoroquinolone resistance in Salmonella: insights by whole-genome sequencing. MICROB GENOMICS. 2018;4(7). https:\/\/doi.org\/10.1099\/mgen.0.000195.","DOI":"10.1099\/mgen.0.000195"},{"key":"4920_CR6","doi-asserted-by":"publisher","unstructured":"Li W, Zhang S, Wang Y, Bian H, Yu S, Huang L, Ma W. Complex probiotics alleviate ampicillin-induced antibiotic-associated diarrhea in mice. FRONT MICROBIOL. 2023;14. https:\/\/doi.org\/10.3389\/fmicb.2023.1156058.","DOI":"10.3389\/fmicb.2023.1156058"},{"key":"4920_CR7","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.anaerobe.2014.05.002","volume":"28","author":"S Uraipan","year":"2014","unstructured":"Uraipan S, Brigidi P, Hongpattarakere T. Antagonistic mechanisms of synbiosis between Lactobacillus plantarum CIF17AN2 and green banana starch in the proximal colon model challenged with Salmonella Typhimurium. Anaerobe. 2014;28:44\u201353. https:\/\/doi.org\/10.1016\/j.anaerobe.2014.05.002.","journal-title":"Anaerobe"},{"key":"4920_CR8","doi-asserted-by":"publisher","first-page":"908010","DOI":"10.3389\/fimmu.2022.908010","volume":"13","author":"T Du","year":"2022","unstructured":"Du T, Lei A, Zhang N, Zhu C. The Beneficial Role of Probiotic Lactobacillus in Respiratory Diseases. FRONT IMMUNOL. 2022;13:908010.","journal-title":"FRONT IMMUNOL"},{"issue":"7","key":"4920_CR9","doi-asserted-by":"publisher","first-page":"5799","DOI":"10.1039\/D0FO00308E","volume":"11","author":"X Li","year":"2020","unstructured":"Li X, Hu D, Tian Y, Song Y, et al. Protective effects of a novelLactobacillus rhamnosus strain with probiotic characteristics against lipopolysaccharide-induced intestinal inflammationin vitro andin vivo. FOOD FUNCT. 2020;11(7):5799\u2013814. https:\/\/doi.org\/10.1039\/D0FO00308E.","journal-title":"FOOD FUNCT"},{"issue":"4","key":"4920_CR10","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1111\/1751-7915.13583","volume":"13","author":"X Bian","year":"2020","unstructured":"Bian X, Yang L, Wu W, Lv L, Jiang X, Wang Q, Wu J, et al. Pediococcus pentosaceus LI05 alleviates DSS-induced colitis by modulating immunological profiles, the gut microbiota and short\u2010chain fatty acid levels in a mouse model. MICROB BIOTECHNOL. 2020;13(4):1228\u201344. https:\/\/doi.org\/10.1111\/1751-7915.13583.","journal-title":"MICROB BIOTECHNOL"},{"issue":"3","key":"4920_CR11","doi-asserted-by":"publisher","first-page":"2077","DOI":"10.18632\/aging.205331","volume":"16","author":"F Xu","year":"2023","unstructured":"Xu F, Chen Z, Xie L, Yang S, Li Y, Wu J, et al. Lactobacillus plantarum ST-III culture supernatant protects against acute alcohol-induced liver and intestinal injury. Aging. 2023;16(3):2077\u201389. https:\/\/doi.org\/10.18632\/aging.205331.","journal-title":"Aging"},{"key":"4920_CR12","doi-asserted-by":"publisher","unstructured":"Amat S, Holman DB, Timsit E, Schwinghamer T et al. Evaluation of the Nasopharyngeal Microbiota in Beef Cattle Transported to a Feedlot, With a Focus on Lactic Acid-Producing Bacteria. Front Microbiol. 2019;10:1988. https:\/\/doi.org\/10.3389\/fmicb.2019.01988.","DOI":"10.3389\/fmicb.2019.01988"},{"key":"4920_CR13","doi-asserted-by":"publisher","unstructured":"Liu X, Jiang N, Wang X, Yan H, Guan L, Kong L et al. Weissella cibaria Relieves Gut Inflammation Caused by Escherichia coli through Inflammation Modulation and Gut Microbiota Regulation. Foods. 2024;13(7):1133. https:\/\/doi.org\/10.3390\/foods13071133.","DOI":"10.3390\/foods13071133"},{"issue":"24","key":"4920_CR14","doi-asserted-by":"publisher","first-page":"3812","DOI":"10.3390\/ani13243812","volume":"13","author":"Y Shao","year":"2023","unstructured":"Shao Y, Wu X, Yu Z, Li M, Sheng T, Wang Z, et al. Gut Microbiome Analysis and Screening of Lactic Acid Bacteria with Probiotic Potential in Anhui Swine. ANIMALS-BASEL. 2023;13(24):3812. https:\/\/doi.org\/10.3390\/ani13243812.","journal-title":"ANIMALS-BASEL"},{"issue":"6","key":"4920_CR15","doi-asserted-by":"publisher","first-page":"6516","DOI":"10.3168\/jds.2020-19034","volume":"104","author":"MI Hossain","year":"2021","unstructured":"Hossain MI, Kim K, Rahaman Mizan MF, Toushik SH, Ashrafudoulla M, Roy PK, Nahar S, Jahid IK, Choi C, Park SH, et al. Comprehensive molecular, probiotic, and quorum-sensing characterization of anti-listerial lactic acid bacteria, and application as bioprotective in a food (milk) model. J DAIRY SCI. 2021;104(6):6516\u201334. https:\/\/doi.org\/10.3168\/jds.2020-19034.","journal-title":"J DAIRY SCI"},{"key":"4920_CR16","doi-asserted-by":"publisher","unstructured":"Zaghloul EH, Ibrahim MIA. Production and Characterization of Exopolysaccharide From Newly Isolated Marine Probiotic Lactiplantibacillus plantarum EI6 With in vitro Wound Healing Activity. FRONT MICROBIOL. 2022;13. https:\/\/doi.org\/10.3389\/fmicb.2022.903363.","DOI":"10.3389\/fmicb.2022.903363"},{"issue":"4","key":"4920_CR17","doi-asserted-by":"publisher","first-page":"4115","DOI":"10.1007\/s42770-024-01474-z","volume":"55","author":"L de Carvalho Maquin\u00e9","year":"2024","unstructured":"de Carvalho Maquin\u00e9 L, Dos Santos Almeida Coelho KW, Da Silva Gomes MF, Vieira JR, et al. In vitro probiotic potential of lactic acid bacteria isolated from the intestines of Muscovy ducks. BRAZ J MICROBIOL. 2024;55(4):4115\u201328. https:\/\/doi.org\/10.1007\/s42770-024-01474-z.","journal-title":"BRAZ J MICROBIOL"},{"key":"4920_CR18","doi-asserted-by":"publisher","first-page":"101840","DOI":"10.1016\/j.fbio.2022.101840","volume":"49","author":"J Lin","year":"2022","unstructured":"Lin J, Xiong T, Peng Z, Xie M, Peng F, et al. Novel lactic acid bacteria with anti-hyperuricemia ability:Screening and in vitro probiotic characteristics. FOOD BIOSCI. 2022;49:101840. https:\/\/doi.org\/10.1016\/j.fbio.2022.101840.","journal-title":"FOOD BIOSCI"},{"issue":"3","key":"4920_CR19","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1007\/s00203-020-02102-8","volume":"203","author":"H Zhang","year":"2021","unstructured":"Zhang H, Xu G, Mao C, Xu Y, Dong W, Inam M, et al. Characterization and complete genome analysis of Bacillus velezensis CB6 revealed ATP synthase subunit \u03b1 against foodborne pathogens. ARCH MICROBIOL. 2021;203(3):1061\u20139. https:\/\/doi.org\/10.1007\/s00203-020-02102-8.","journal-title":"ARCH MICROBIOL"},{"key":"4920_CR20","doi-asserted-by":"publisher","first-page":"110695","DOI":"10.1016\/j.ijfoodmicro.2024.110695","volume":"417","author":"GKV de Vasconcelos Medeiros","year":"2024","unstructured":"de Vasconcelos Medeiros GKV, Martins ACS, Vasconcelos MG, Garcia EF, Rodrigues NPA, de Albuquerque TMR, Viera VB, et al. Cereus jamacaru DC. (mandacaru) fruit as a source of lactic acid bacteria with in vitro probiotic-related characteristics and its protective effects on Pediococcus pentosaceus during lyophilization and refrigeration storage. INT J FOOD MICROBIOL. 2024;417:110695. https:\/\/doi.org\/10.1016\/j.ijfoodmicro.2024.110695.","journal-title":"INT J FOOD MICROBIOL"},{"key":"4920_CR21","doi-asserted-by":"publisher","unstructured":"Abbasiliasi S, Tan JS, Bashokouh F, Ibrahim TAT, Mustafa S, Vakhshiteh F, Sivasamboo S, Ariff AB. In vitro assessment of Pediococcus acidilactici Kp10 for its potential use in the food industry. BMC MICROBIOL. 2017;17(1). https:\/\/doi.org\/10.1186\/s12866-017-1000-z.","DOI":"10.1186\/s12866-017-1000-z"},{"key":"4920_CR22","doi-asserted-by":"publisher","unstructured":"Wang J, Gao M, Wang J, Zeng Y, Wang C, Cao X. LGG promotes activation of intestinal ILC3 through TLR2 receptor and inhibitssalmonella typhimurium infection in mice. VIRULENCE. 2024;15(1). https:\/\/doi.org\/10.1080\/21505594.2024.2384553.","DOI":"10.1080\/21505594.2024.2384553"},{"key":"4920_CR23","doi-asserted-by":"publisher","unstructured":"Fang J, Yang Y, Xie W. Chinese expert consensus on the application of live combined Bifidobacterium, Lactobacillus, and Enterococcus powder\/capsule in digestive system diseases (2021). J Gastroen Hepatol. 2023;38(7):1089\u20131098. https:\/\/doi.org\/10.1111\/jgh.16195.","DOI":"10.1111\/jgh.16195"},{"key":"4920_CR24","doi-asserted-by":"publisher","unstructured":"Bao W, He Y, Yu J, Liu M, Yang X, Ta N, et al. Regulatory Effect of Lactiplantibacillus plantarum 2\u201333 on Intestinal Microbiota of Mice With Antibiotic-Associated Diarrhea. FRONT NUTR. 2022;9. https:\/\/doi.org\/10.3389\/fnut.2022.921875.","DOI":"10.3389\/fnut.2022.921875"},{"issue":"3","key":"4920_CR25","doi-asserted-by":"publisher","first-page":"2355","DOI":"10.3390\/ijms24032355","volume":"24","author":"M Shi","year":"2023","unstructured":"Shi M, Song R, Gu L. Different Regulatory Effects of Heated Products and Maillard Reaction Products of Half-Fin Anchovy Hydrolysates on Intestinal Antioxidant Defense in Healthy Animals. Int J Mol Sci. 2023;24(3):2355. https:\/\/doi.org\/10.3390\/ijms24032355.","journal-title":"Int J Mol Sci"},{"issue":"6","key":"4920_CR26","doi-asserted-by":"publisher","first-page":"2253","DOI":"10.1016\/S0002-9440(10)61172-8","volume":"160","author":"E Balish","year":"2002","unstructured":"Balish E, Warner T. Enterococcus faecalis Induces Inflammatory Bowel Disease in Interleukin-10 Knockout Mice. Am J Pathol. 2002;160(6):2253\u20137. https:\/\/doi.org\/10.1016\/S0002-9440(10)61172-8.","journal-title":"Am J Pathol"},{"key":"4920_CR27","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.actbio.2024.02.034","volume":"178","author":"J Yao","year":"2024","unstructured":"Yao J, Chen Y, Zhang L, Cheng Y, Chen Z, Zhang Y, et al. pH-responsive CuS\/DSF\/EL\/PVP nanoplatform alleviates inflammatory bowel disease in mice via regulating gut immunity and microbiota. ACTA BIOMATER. 2024;178:265\u201386. https:\/\/doi.org\/10.1016\/j.actbio.2024.02.034.","journal-title":"ACTA BIOMATER"},{"issue":"20","key":"4920_CR28","doi-asserted-by":"publisher","first-page":"23689","DOI":"10.18632\/aging.203641","volume":"13","author":"Y Chen","year":"2021","unstructured":"Chen Y, Ma C, Liu L, He J, Zhu C, Zheng F, et al. Analysis of gut microbiota and metabolites in patients with rheumatoid arthritis and identification of potential biomarkers. Aging (Albany NY). 2021;13(20):23689\u2013701. https:\/\/doi.org\/10.18632\/aging.203641.","journal-title":"Aging (Albany NY)"},{"key":"4920_CR29","doi-asserted-by":"publisher","first-page":"130002","DOI":"10.1016\/j.biortech.2023.130002","volume":"392","author":"J Zhang","year":"2024","unstructured":"Zhang J, Zhao J, Fu Q, Liu H, Li M, Wang Z, Gu W, Zhu X, Lin R, et al. Metabolic engineering of Paenibacillus polymyxa for effective production of 2,3-butanediol from poplar hydrolysate. BIORESOURCE TECHNOL. 2024;392:130002. https:\/\/doi.org\/10.1016\/j.biortech.2023.130002.","journal-title":"BIORESOURCE TECHNOL"},{"key":"4920_CR30","doi-asserted-by":"publisher","unstructured":"Gunn JS. Mechanisms of bacterial resistance and response to bile. Lausanne, Amsterdam, Paris: Elsevier SAS. 2000;2:907\u201313. https:\/\/doi.org\/10.1016\/s1286-4579(00)00392-0.","DOI":"10.1016\/s1286-4579(00)00392-0"},{"key":"4920_CR31","doi-asserted-by":"publisher","unstructured":"Huang Q, Xing J, Tang F, Ren J, Wang C, Xue F. Recombinant Lactiplantibacilllus plantarum modulate gut microbial diversity and function. BMC Microbiol. 2024;24(1). https:\/\/doi.org\/10.1186\/s12866-024-03570-4.","DOI":"10.1186\/s12866-024-03570-4"},{"key":"4920_CR32","doi-asserted-by":"publisher","unstructured":"Xing J, Niu T, Zou B, Yang G, Shi C, Yan Q, Sun M, Yu T, et al. Gut microbiota-derived LCA mediates the protective effect of PEDV infection in piglets. MICROBIOME. 2024;12(1). https:\/\/doi.org\/10.1186\/s40168-023-01734-4.","DOI":"10.1186\/s40168-023-01734-4"},{"issue":"4","key":"4920_CR33","doi-asserted-by":"publisher","first-page":"676","DOI":"10.3390\/microorganisms10040676","volume":"10","author":"B Dixon","year":"2022","unstructured":"Dixon B, Kilonzo-Nthenge A, Nzomo M, Bhogoju S, Nahashon S. Evaluation of Selected Bacteria and Yeast for Probiotic Potential in Poultry Production. MICROORGANISMS. 2022;10(4):676. https:\/\/doi.org\/10.3390\/microorganisms10040676.","journal-title":"MICROORGANISMS"},{"issue":"11","key":"4920_CR34","doi-asserted-by":"publisher","first-page":"e21558","DOI":"10.1016\/j.heliyon.2023.e21558","volume":"9","author":"S Rold\u00e1n-P\u00e9rez","year":"2023","unstructured":"Rold\u00e1n-P\u00e9rez S, G\u00f3mez Rodr\u00edguez SL, Sep\u00falveda-Valencia JU, Ruiz Villadiego OS, M\u00e1rquez Fern\u00e1ndez ME, Montoya Campuzano OI, Durango-Zuleta MM. Assessment of probiotic properties of lactic acid bacteria isolated from an artisanal Colombian cheese. HELIYON. 2023;9(11):e21558. https:\/\/doi.org\/10.1016\/j.heliyon.2023.e21558.","journal-title":"HELIYON"},{"key":"4920_CR35","doi-asserted-by":"publisher","first-page":"116288","DOI":"10.1016\/j.lwt.2024.116288","volume":"202","author":"H Shu","year":"2024","unstructured":"Shu H, He X, Hong Z, Dong K, Zou Y, Cao M, et al. Screening and genome analysis of potential probiotic lactic acid bacteria with broad-spectrum antibacterial activity from Sichuan sun-dried vinegar grains (Cupei). LWT. 2024;202:116288. https:\/\/doi.org\/10.1016\/j.lwt.2024.116288.","journal-title":"LWT"},{"issue":"2","key":"4920_CR36","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1007\/s00726-022-03165-1","volume":"11","author":"Y Liu","year":"2020","unstructured":"Liu Y, Sheng Y, Pan Q, Xue Y, Yu L, Tian F, et al. Identification of the key physiological characteristics ofLactobacillus plantarum strains for ulcerative colitis alleviation. FOOD FUNCT. 2020;11(2):1279\u201391. https:\/\/doi.org\/10.1007\/s00726-022-03165-1.","journal-title":"FOOD FUNCT"},{"issue":"5","key":"4920_CR37","doi-asserted-by":"publisher","first-page":"5166","DOI":"10.3168\/jds.2020-19398","volume":"104","author":"Y Jin","year":"2021","unstructured":"Jin Y, Luo B, Cai J, Yang B, Zhang Y, Tian F, Ni Y. Evaluation of indigenous lactic acid bacteria of raw mare milk from pastoral areas in Xinjiang, China, for potential use in probiotic fermented dairy products. J DAIRY SCI. 2021;104(5):5166\u201384. https:\/\/doi.org\/10.3168\/jds.2020-19398.","journal-title":"J DAIRY SCI"},{"key":"4920_CR38","doi-asserted-by":"publisher","first-page":"108931","DOI":"10.1016\/j.foodres.2019.108931","volume":"130","author":"A Tarrah","year":"2020","unstructured":"Tarrah A, Da Silva Duarte V, Pakroo S, Corich V, Giacomini A. Genomic and phenotypic assessments of safety and probiotic properties of Streptococcus macedonicus strains of dairy origin. FOOD RES INT. 2020;130:108931. https:\/\/doi.org\/10.1016\/j.foodres.2019.108931.","journal-title":"FOOD RES INT"},{"key":"4920_CR39","doi-asserted-by":"publisher","first-page":"106404","DOI":"10.1016\/j.jff.2024.106404","volume":"121","author":"G Ou","year":"2024","unstructured":"Ou G, Zhou T, Zhu P, Zhu W, Wei X, Huang R, Jing J, You Z, et al. Polysaccharides from Dendrobium devonianum ameliorate Salmonella typhimurium-induced ulcerative colitis by modulating ClostridiumXlVa, purine and tryptophan metabolism. J FUNCT FOODS. 2024;121:106404. https:\/\/doi.org\/10.1016\/j.jff.2024.106404.","journal-title":"J FUNCT FOODS"},{"key":"4920_CR40","doi-asserted-by":"publisher","first-page":"299","DOI":"10.3389\/fmicb.2019.00299","volume":"10","author":"J Liu","year":"2019","unstructured":"Liu J, Gu Z, Song F, Zhang H, Zhao J, Chen W. Lactobacillus plantarum ZS2058 and Lactobacillus rhamnosus GG Use Different Mechanisms to Prevent Salmonella Infection in vivo. FRONT MICROBIOL. 2019;10:299. https:\/\/doi.org\/10.3389\/fmicb.2019.00299.","journal-title":"FRONT MICROBIOL"},{"issue":"6","key":"4920_CR41","doi-asserted-by":"publisher","first-page":"2578","DOI":"10.1128\/AEM.66.6.2578-2588.2000","volume":"66","author":"GW Tannock","year":"2000","unstructured":"Tannock GW, Munro K, Harmsen HJM, Welling GW, et al. Analysis of the Fecal Microflora of Human Subjects Consuming a Probiotic Product Containing Lactobacillus rhamnosus DR20. APPL ENVIRON MICROB. 2000;66(6):2578\u201388. https:\/\/doi.org\/10.1128\/AEM.66.6.2578-2588.2000.","journal-title":"APPL ENVIRON MICROB"},{"issue":"8","key":"4920_CR42","doi-asserted-by":"publisher","first-page":"2316","DOI":"10.1007\/s10620-009-1016-9","volume":"55","author":"F Ljuca","year":"2010","unstructured":"Ljuca F, Gegic A, Salkic NN, Pavlovic-Calic N. Circulating Cytokines Reflect Mucosal Inflammatory Status in Patients with Crohn\u2019s Disease. DIGEST DIS SCI. 2010;55(8):2316\u201326.","journal-title":"DIGEST DIS SCI"},{"key":"4920_CR43","doi-asserted-by":"publisher","first-page":"105326","DOI":"10.1016\/j.fbio.2024.105326","volume":"62","author":"H Li","year":"2024","unstructured":"Li H, Guo X, Liu X, Zhao J, Chen W, Yang B. Protective effect of a cocktail of lactic acid bacteria on DSS-induced ulcerative colitis via activating the TGR5\/PKA pathway. FOOD BIOSCI. 2024;62:105326. https:\/\/doi.org\/10.1016\/j.fbio.2024.105326.","journal-title":"FOOD BIOSCI"},{"key":"4920_CR44","doi-asserted-by":"publisher","first-page":"109658","DOI":"10.1016\/j.jnutbio.2024.109658","volume":"130","author":"P Guan","year":"2024","unstructured":"Guan P, Yu H, Wang S, Sun J, Chai X, et al. Dietary rutin alleviated the damage by cold stress on inflammation reaction, tight junction protein and intestinal microbial flora in the mice intestine. J Nutr Biochem. 2024;130:109658. https:\/\/doi.org\/10.1016\/j.jnutbio.2024.109658.","journal-title":"J Nutr Biochem"},{"issue":"20","key":"4920_CR45","doi-asserted-by":"publisher","first-page":"e38701","DOI":"10.1016\/j.heliyon.2024.e38701","volume":"10","author":"B Li","year":"2024","unstructured":"Li B, Xun Q, Wei C, Yu B, Pan X, Shen Q. Effects of Shaofu Zhuyu decoction on intestinal flora and fibrosis in a mouse model of endometriosis. HELIYON. 2024;10(20):e38701.","journal-title":"HELIYON"},{"key":"4920_CR46","doi-asserted-by":"publisher","unstructured":"Gazzaniga FS, Camacho DM, Wu M, Silva Palazzo MF, Dinis ALM, et al. Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection. FRONT CELL INFECT MI. 2021;11. https:\/\/doi.org\/10.3389\/fcimb.2021.638014.","DOI":"10.3389\/fcimb.2021.638014"},{"key":"4920_CR47","doi-asserted-by":"publisher","unstructured":"Li Z, Zhang C, Li B, Zhang S, Haj FG, Zhang G, Lee Y. The modulatory effects of alfalfa polysaccharide on intestinal microbiota and systemic health of Salmonella serotype (ser.) Enteritidis-challenged broilers. SCI REP-UK. 2021;11(1). https:\/\/doi.org\/10.1038\/s41598-021-90060-6.","DOI":"10.1038\/s41598-021-90060-6"},{"issue":"11","key":"4920_CR48","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.3390\/microorganisms8111715","volume":"8","author":"S Stojanov","year":"2020","unstructured":"Stojanov S, Berlec A, \u0160trukelj B. The Influence of Probiotics on the Firmicutes\/Bacteroidetes Ratio in the Treatment of Obesity and Inflammatory Bowel disease. MICROORGANISMS. 2020;8(11):1715. https:\/\/doi.org\/10.3390\/microorganisms8111715.","journal-title":"MICROORGANISMS"},{"key":"4920_CR49","doi-asserted-by":"publisher","first-page":"886061","DOI":"10.3389\/fcimb.2022.886061","volume":"12","author":"Y Zhu","year":"2022","unstructured":"Zhu Y, Xu Y, Wang X, Rao L, Yan X, Gao R, et al. Probiotic Cocktail Alleviates Intestinal Inflammation Through Improving Gut Microbiota and Metabolites in Colitis Mice. FRONT CELL INFECT MI. 2022;12:886061. https:\/\/doi.org\/10.3389\/fcimb.2022.886061.","journal-title":"FRONT CELL INFECT MI"},{"issue":"19","key":"4920_CR50","doi-asserted-by":"publisher","first-page":"10023","DOI":"10.1039\/d2fo01747d","volume":"13","author":"J Zhao","year":"2022","unstructured":"Zhao J, Wang Y, Wang J, Lv M, Zhou C, Jia L. Lactobacillus kefiranofaciens ZW18 from Kefir enhances the anti-tumor effect of anti-programmed cell death 1 (PD-1) immunotherapy by modulating the gut microbiota. FOOD FUNCT. 2022;13(19):10023\u201333. https:\/\/doi.org\/10.1039\/d2fo01747d.","journal-title":"FOOD FUNCT"},{"key":"4920_CR51","doi-asserted-by":"publisher","DOI":"10.1101\/2025.04.30.651474","author":"RC Lopez","year":"2025","unstructured":"Lopez RC, Juan AB, Maria Gloria DBMMSA. Imbalance in gut microbial interactions as a marker of health and disease. bioRxiv. 2025. https:\/\/doi.org\/10.1101\/2025.04.30.651474.","journal-title":"bioRxiv"},{"issue":"1","key":"4920_CR52","doi-asserted-by":"publisher","first-page":"wrae187","DOI":"10.1093\/ismejo\/wrae187","volume":"18","author":"I Leleiwi","year":"2024","unstructured":"Leleiwi I, Kokkinias K, Kim Y, Baniasad M, Shaffer M, Sabag-Daigle A, et al. Gut microbiota carbon and sulfur metabolisms supportSalmonella infections. ISME J. 2024;18(1):wrae187. https:\/\/doi.org\/10.1093\/ismejo\/wrae187.","journal-title":"ISME J"},{"key":"4920_CR53","doi-asserted-by":"publisher","first-page":"102486","DOI":"10.1016\/j.fbio.2023.102486","volume":"53","author":"Y Liu","year":"2023","unstructured":"Liu Y, Zhang D, Ning Q, Wang J. Growth characteristics and metabonomics analysis of Lactobacillus rhamnosus GG in Ganoderma lucidum aqueous extract medium. FOOD BIOSCI. 2023;53:102486. https:\/\/doi.org\/10.1016\/j.fbio.2023.102486.","journal-title":"FOOD BIOSCI"},{"issue":"7","key":"4920_CR54","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1093\/gerona\/glab019","volume":"76","author":"G Azhar","year":"2021","unstructured":"Azhar G, Wei JY, Schutzler SE, Coker K, Gibson RV, Kirby MF, et al. Daily Consumption of a Specially Formulated Essential Amino Acid-Based Dietary Supplement Improves Physical Performance in Older Adults With Low Physical Functioning. Journals Gerontology: Ser A. 2021;76(7):1184\u201391. https:\/\/doi.org\/10.1093\/gerona\/glab019.","journal-title":"Journals Gerontology: Ser A"},{"issue":"10","key":"4920_CR55","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1007\/s00726-022-03165-1","volume":"54","author":"Y Liu","year":"2022","unstructured":"Liu Y, Tian X, Daniel RC, Okeugo B, Armbrister SA, Luo M, Taylor CM, Wu G, Rhoads JM. Impact of probiotic Limosilactobacillus reuteri DSM 17938 on amino acid metabolism in the healthy newborn mouse. Amino Acids. 2022;54(10):1383\u2013401. https:\/\/doi.org\/10.1007\/s00726-022-03165-1.","journal-title":"Amino Acids"},{"key":"4920_CR56","doi-asserted-by":"publisher","first-page":"114985","DOI":"10.1016\/j.biopha.2023.114985","volume":"164","author":"M Zhao","year":"2023","unstructured":"Zhao M, Chu J, Feng S, Guo C, Xue B, He K, Li L. Immunological mechanisms of inflammatory diseases caused by gut microbiota dysbiosis: A review. BIOMED PHARMACOTHER. 2023;164:114985. https:\/\/doi.org\/10.1016\/j.biopha.2023.114985.","journal-title":"BIOMED PHARMACOTHER"},{"issue":"1","key":"4920_CR57","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1038\/s41467-024-45636-x","volume":"15","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Tu S, Ji X, Wu J, Meng J, Gao J, et al. Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway. NAT COMMUN. 2024;15(1):1333. https:\/\/doi.org\/10.1038\/s41467-024-45636-x.","journal-title":"NAT COMMUN"},{"issue":"5","key":"4920_CR58","doi-asserted-by":"publisher","first-page":"4716","DOI":"10.3390\/ijms24054716","volume":"24","author":"J Zhao","year":"2023","unstructured":"Zhao J, Zhao Y, Liu H, Cao Q, Feng L, et al. Dietary Leucine Improves Fish Intestinal Barrier Function by Increasing Humoral Immunity, Antioxidant Capacity, and Tight Junction. Int J Mol Sci. 2023;24(5):4716. https:\/\/doi.org\/10.3390\/ijms24054716.","journal-title":"Int J Mol Sci"}],"container-title":["BMC Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12866-026-04920-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12866-026-04920-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12866-026-04920-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:54:43Z","timestamp":1777337683000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1186\/s12866-026-04920-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,19]]},"references-count":58,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4920"],"URL":"https:\/\/doi.org\/10.1186\/s12866-026-04920-0","relation":{},"ISSN":["1471-2180"],"issn-type":[{"value":"1471-2180","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,19]]},"assertion":[{"value":"15 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Laboratory Animal Ethics Committee of Jilin Agricultural University with the protocol code 20230317002.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"405"}}