{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:14:38Z","timestamp":1790716478613,"version":"4.1.0"},"reference-count":65,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,3,14]],"date-time":"2015-03-14T00:00:00Z","timestamp":1426291200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Neurosci"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1186\/s12868-015-0150-x","type":"journal-article","created":{"date-parts":[[2015,3,13]],"date-time":"2015-03-13T12:13:57Z","timestamp":1426248837000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Differential roles of hippocampal glutamatergic receptors in neuropathic anxiety-like behavior after partial sciatic nerve ligation in rats"],"prefix":"10.1186","volume":"16","author":[{"given":"Xue-Qin","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Lin","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Bin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Tao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Yi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru-Ping","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhou","family":"Xin-Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Qi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Yuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang-Fang","family":"Bi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,3,14]]},"reference":[{"issue":"5472","key":"150_CR1","doi-asserted-by":"publisher","first-page":"1769","DOI":"10.1126\/science.288.5472.1769","volume":"288","author":"DD Price","year":"2000","unstructured":"Price DD. Psychological and neural mechanisms of the affective dimension of pain. Science. 2000;288(5472):1769\u201372.","journal-title":"Science"},{"issue":"Suppl 1","key":"150_CR2","doi-asserted-by":"publisher","first-page":"S9","DOI":"10.1111\/j.1526-4637.2004.04019.x","volume":"5","author":"B Nicholson","year":"2004","unstructured":"Nicholson B, Verma S. Comorbidities in chronic neuropathic pain. Pain Med. 2004;5 Suppl 1:S9\u201327.","journal-title":"Pain Med"},{"issue":"9","key":"150_CR3","doi-asserted-by":"publisher","first-page":"1762","DOI":"10.1016\/j.pain.2014.05.031","volume":"155","author":"A Sawada","year":"2014","unstructured":"Sawada A, Niiyama Y, Ataka K, Nagaishi K, Yamakage M, Fujimiya M. Suppression of bone marrow-derived microglia in the amygdala improves anxiety-like behavior induced by chronic partial sciatic nerve ligation in mice. Pain. 2014;155(9):1762\u201372.","journal-title":"Pain"},{"key":"150_CR4","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.neubiorev.2014.08.002","volume":"47C","author":"I Yalcin","year":"2014","unstructured":"Yalcin I, Barthas F, Barrot M. Emotional consequences of neuropathic pain: Insight from preclinical studies. Neurosci Biobehav Rev. 2014;47C:154\u201364.","journal-title":"Neurosci Biobehav Rev"},{"key":"150_CR5","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1016\/j.pbb.2014.06.018","volume":"124C","author":"O Caspani","year":"2014","unstructured":"Caspani O, Reitz MC, Ceci A, Kremer A, Treede RD. Tramadol reduces anxiety-related and depression-associated behaviors presumably induced by pain in the chronic constriction injury model of neuropathic pain in rats. Pharmacol Biochem Behav. 2014;124C:290\u20136.","journal-title":"Pharmacol Biochem Behav"},{"issue":"11","key":"150_CR6","doi-asserted-by":"publisher","first-page":"2218","DOI":"10.1016\/j.pain.2012.07.007","volume":"153","author":"H Leite-Almeida","year":"2012","unstructured":"Leite-Almeida H, Cerqueira JJ, Wei H, Ribeiro-Costa N, Anjos-Martins H, Sousa N, et al. Differential effects of left\/right neuropathy on rats\u2019 anxiety and cognitive behavior. Pain. 2012;153(11):2218\u201325.","journal-title":"Pain"},{"issue":"8","key":"150_CR7","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1016\/j.jpain.2006.01.458","volume":"7","author":"V Duric","year":"2006","unstructured":"Duric V, McCarson KE. Persistent pain produces stress-like alterations in hippocampal neurogenesis and gene expression. J Pain. 2006;7(8):544\u201355.","journal-title":"J Pain"},{"issue":"4","key":"150_CR8","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1097\/ALN.0000000000000403","volume":"121","author":"M Tajerian","year":"2014","unstructured":"Tajerian M, Leu D, Zou Y, Sahbaie P, Li W, Khan H, et al. Brain neuroplastic changes accompany anxiety and memory deficits in a model of complex regional pain syndrome. Anesthesiology. 2014;121(4):852\u201365.","journal-title":"Anesthesiology"},{"issue":"5","key":"150_CR9","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1152\/jn.00611.2013","volume":"111","author":"AA Mutso","year":"2014","unstructured":"Mutso AA, Petre B, Huang L, Baliki MN, Torbey S, Herrmann KM, et al. Reorganization of hippocampal functional connectivity with transition to chronic back pain. J Neurophysiol. 2014;111(5):1065\u201376.","journal-title":"J Neurophysiol"},{"issue":"2\u20133","key":"150_CR10","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.ejphar.2007.07.054","volume":"574","author":"D Kodama","year":"2007","unstructured":"Kodama D, Ono H, Tanabe M. Altered hippocampal long-term potentiation after peripheral nerve injury in mice. Eur J Pharmacol. 2007;574(2\u20133):127\u201332.","journal-title":"Eur J Pharmacol"},{"issue":"8","key":"150_CR11","doi-asserted-by":"publisher","first-page":"1472","DOI":"10.1016\/j.pain.2014.04.022","volume":"155","author":"SA Khan","year":"2014","unstructured":"Khan SA, Keaser ML, Meiller TF, Seminowicz DA. Altered structure and function in the hippocampus and medial prefrontal cortex in patients with burning mouth syndrome. Pain. 2014;155(8):1472\u201380.","journal-title":"Pain"},{"key":"150_CR12","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/1744-8069-9-21","volume":"9","author":"S Alvarado","year":"2013","unstructured":"Alvarado S, Tajerian M, Millecamps M, Suderman M, Stone LS, Szyf M. Peripheral nerve injury is accompanied by chronic transcriptome-wide changes in the mouse prefrontal cortex. Mol Pain. 2013;9:21.","journal-title":"Mol Pain"},{"issue":"17","key":"150_CR13","doi-asserted-by":"publisher","first-page":"5747","DOI":"10.1523\/JNEUROSCI.0587-12.2012","volume":"32","author":"AA Mutso","year":"2012","unstructured":"Mutso AA, Radzicki D, Baliki MN, Huang L, Banisadr G, Centeno MV, et al. Abnormalities in hippocampal functioning with persistent pain. J Soc Neuroscience. 2012;32(17):5747\u201356.","journal-title":"J Soc Neuroscience"},{"issue":"15","key":"150_CR14","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.2174\/138161209788186272","volume":"15","author":"MF Jarvis","year":"2009","unstructured":"Jarvis MF, Boyce-Rustay JM. Neuropathic pain: models and mechanisms. Curr Pharm Des. 2009;15(15):1711\u20136.","journal-title":"Curr Pharm Des"},{"issue":"18","key":"150_CR15","doi-asserted-by":"publisher","first-page":"7825","DOI":"10.1523\/JNEUROSCI.5583-12.2013","volume":"33","author":"YC Ho","year":"2013","unstructured":"Ho YC, Cheng JK, Chiou LC. Hypofunction of glutamatergic neurotransmission in the periaqueductal gray contributes to nerve-injury-induced neuropathic pain. J Society Neuroscience. 2013;33(18):7825\u201336.","journal-title":"J Society Neuroscience"},{"issue":"4","key":"150_CR16","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1016\/j.pbb.2011.11.002","volume":"100","author":"S Siegel","year":"2012","unstructured":"Siegel S, Sanacora G. The roles of glutamate receptors across major neurological and psychiatric disorders. Pharmacol Biochem Behav. 2012;100(4):653\u20135.","journal-title":"Pharmacol Biochem Behav"},{"issue":"1","key":"150_CR17","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.pharep.2013.06.005","volume":"66","author":"X Shen","year":"2014","unstructured":"Shen X, Liu Y, Xu S, Zhao Q, Wu H, Guo X, et al. Menin regulates spinal glutamate-GABA balance through GAD65 contributing to neuropathic pain. Pharmacological Reports. 2014;66(1):49\u201355.","journal-title":"Pharmacological Reports"},{"issue":"1\u20132","key":"150_CR18","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.neulet.2006.01.018","volume":"399","author":"C Ultenius","year":"2006","unstructured":"Ultenius C, Linderoth B, Meyerson BA, Wallin J. Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat. Neurosci Lett. 2006;399(1\u20132):85\u201390.","journal-title":"Neurosci Lett"},{"issue":"9","key":"150_CR19","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1111\/ejn.12516","volume":"39","author":"W Chen","year":"2014","unstructured":"Chen W, Walwyn W, Ennes HS, Kim H, McRoberts JA, Marvizon JC. BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals. Eur J Neurosci. 2014;39(9):1439\u201354.","journal-title":"Eur J Neurosci"},{"issue":"5","key":"150_CR20","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1002\/syn.20859","volume":"65","author":"K Niikura","year":"2011","unstructured":"Niikura K, Furuya M, Narita M, Torigoe K, Kobayashi Y, Takemura Y, et al. Enhancement of glutamatergic transmission in the cingulate cortex in response to mild noxious stimuli under a neuropathic pain-like state. Synapse. 2011;65(5):424\u201332.","journal-title":"Synapse"},{"issue":"2","key":"150_CR21","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/0304-3959(90)91074-S","volume":"43","author":"Z Seltzer","year":"1990","unstructured":"Seltzer Z, Dubner R, Shir Y. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain. 1990;43(2):205\u201318.","journal-title":"Pain"},{"issue":"1","key":"150_CR22","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1006\/exnr.2002.7897","volume":"175","author":"L Li","year":"2002","unstructured":"Li L, Xian CJ, Zhong JH, Zhou XF. Effect of lumbar 5 ventral root transection on pain behaviors: a novel rat model for neuropathic pain without axotomy of primary sensory neurons. Exp Neurol. 2002;175(1):23\u201334.","journal-title":"Exp Neurol"},{"issue":"1","key":"150_CR23","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1046\/j.1460-9568.2000.00884.x","volume":"12","author":"XF Zhou","year":"2000","unstructured":"Zhou XF, Deng YS, Xian CJ, Zhong JH. Neurotrophins from dorsal root ganglia trigger allodynia after spinal nerve injury in rats. Eur J Neurosci. 2000;12(1):100\u20135.","journal-title":"Eur J Neurosci"},{"issue":"3","key":"150_CR24","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1097\/ALN.0b013e3182242045","volume":"115","author":"RP Dai","year":"2011","unstructured":"Dai RP, Li CQ, Zhang JW, Li F, Shi XD, Zhang JY, et al. Biphasic activation of extracellular signal-regulated kinase in anterior cingulate cortex distinctly regulates the development of pain-related anxiety and mechanical hypersensitivity in rats after incision. Anesthesiology. 2011;115(3):604\u201313.","journal-title":"Anesthesiology"},{"key":"150_CR25","doi-asserted-by":"publisher","first-page":"705874","DOI":"10.1155\/2010\/705874","volume":"2010","author":"CQ Li","year":"2010","unstructured":"Li CQ, Zhang JW, Dai RP, Wang J, Luo XG, Zhou XF. Surgical incision induces anxiety-like behavior and amygdala sensitization: effects of morphine and gabapentin. Pain Res Treatment. 2010;2010:705874.","journal-title":"Pain Res Treatment"},{"issue":"4","key":"150_CR26","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1267\/ahc.12002","volume":"45","author":"XL Zhong","year":"2012","unstructured":"Zhong XL, Wei R, Zhou P, Luo YW, Wang XQ, Duan J, et al. Activation of Anterior Cingulate Cortex Extracellular Signal-Regulated Kinase-1 and \u22122 (ERK1\/2) Regulates Acetic Acid-Induced, Pain-Related Anxiety in Adult Female Mice. Acta histochemica et cytochemica. 2012;45(4):219\u201325.","journal-title":"Acta histochemica et cytochemica"},{"issue":"12","key":"150_CR27","doi-asserted-by":"publisher","first-page":"2777","DOI":"10.1038\/npp.2014.128","volume":"39","author":"CQ Li","year":"2014","unstructured":"Li CQ, Luo YW, Bi FF, Cui TT, Song L, Cao WY, et al. Development of anxiety-like behavior via Hippocampal IGF-2 signaling in the offspring of parental morphine exposure: effect of enriched environment. Neuropsychopharmacology. 2014;39(12):2777\u201387.","journal-title":"Neuropsychopharmacology"},{"key":"150_CR28","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.bbr.2014.02.022","volume":"265","author":"W Cao","year":"2014","unstructured":"Cao W, Duan J, Wang X, Zhong X, Hu Z, Huang F, et al. Early enriched environment induces an increased conversion of proBDNF to BDNF in the adult rat\u2019s hippocampus. Behav Brain Res. 2014;265:76\u201383.","journal-title":"Behav Brain Res"},{"key":"150_CR29","doi-asserted-by":"publisher","first-page":"4","DOI":"10.3389\/fncel.2014.00004","volume":"8","author":"AR Nath","year":"2014","unstructured":"Nath AR, Chen RH, Stanley EF. Cryoloading: introducing large molecules into live synaptosomes. Front Cell Neurosci. 2014;8:4.","journal-title":"Front Cell Neurosci"},{"issue":"34","key":"150_CR30","doi-asserted-by":"publisher","first-page":"14502","DOI":"10.1073\/pnas.0903894106","volume":"106","author":"M Miyaji","year":"2009","unstructured":"Miyaji M, Kortum RL, Surana R, Li W, Woolard KD, Simpson RM, et al. Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice. Proc Natl Acad Sci U S A. 2009;106(34):14502\u20137.","journal-title":"Proc Natl Acad Sci U S A"},{"key":"150_CR31","first-page":"318","volume":"89C","author":"YW Luo","year":"2014","unstructured":"Luo YW, Xu Y, Cao WY, Zhong XL, Duan J, Wang XQ, et al. Insulin-like growth factor 2 mitigates depressive behavior in a rat model of chronic stress. Neuropharmacology. 2014;89C:318\u201324.","journal-title":"Neuropharmacology"},{"key":"150_CR32","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1744-8069-4-27","volume":"4","author":"CQ Li","year":"2008","unstructured":"Li CQ, Xu JM, Liu D, Zhang JY, Dai RP. Brain derived neurotrophic factor (BDNF) contributes to the pain hypersensitivity following surgical incision in the rats. Mol Pain. 2008;4:27.","journal-title":"Mol Pain"},{"key":"150_CR33","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.brainres.2013.08.046","volume":"1538","author":"WY Cao","year":"2013","unstructured":"Cao WY, Xu Y, Luo YW, Zhong XL, Duan J, Wang XQ, et al. Activation of ERK1\/2 is required for normal response of isosexual social interactions in male rats. Brain Res. 2013;1538:51\u201360.","journal-title":"Brain Res"},{"key":"150_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.neuropharm.2014.06.021","volume":"86","author":"GD Guercio","year":"2014","unstructured":"Guercio GD, Bevictori L, Vargas-Lopes C, Madeira C, Oliveira A, Carvalho VF, et al. D-serine prevents cognitive deficits induced by acute stress. Neuropharmacology. 2014;86:1\u20138.","journal-title":"Neuropharmacology"},{"issue":"1\u20132","key":"150_CR35","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/S0304-3959(03)00301-4","volume":"106","author":"LA McWilliams","year":"2003","unstructured":"McWilliams LA, Cox BJ, Enns MW. Mood and anxiety disorders associated with chronic pain: an examination in a nationally representative sample. Pain. 2003;106(1\u20132):127\u201333.","journal-title":"Pain"},{"issue":"1","key":"150_CR36","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1186\/s13041-014-0072-z","volume":"7","author":"H Jiang","year":"2014","unstructured":"Jiang H, Fang D, Kong LY, Jin ZR, Cai J, Kang XJ, et al. Sensitization of neurons in the central nucleus of the amygdala via the decreased GABAergic inhibition contributes to the development of neuropathic pain-related anxiety-like behaviors in rats. Mol Brain. 2014;7(1):72.","journal-title":"Mol Brain"},{"issue":"4","key":"150_CR37","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1038\/sj.npp.1300858","volume":"31","author":"M Narita","year":"2006","unstructured":"Narita M, Kaneko C, Miyoshi K, Nagumo Y, Kuzumaki N, Nakajima M, et al. Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala. Neuropsychopharmacology. 2006;31(4):739\u201350.","journal-title":"Neuropsychopharmacology"},{"key":"150_CR38","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.neuropharm.2014.01.020","volume":"79","author":"BM Gai","year":"2014","unstructured":"Gai BM, Bortolatto CF, Bruning CA, Zborowski VA, Stein AL, Zeni G, et al. Depression-related behavior and mechanical allodynia are blocked by 3-(4-fluorophenylselenyl)-2,5-diphenylselenophene in a mouse model of neuropathic pain induced by partial sciatic nerve ligation. Neuropharmacology. 2014;79:580\u20139.","journal-title":"Neuropharmacology"},{"issue":"10","key":"150_CR39","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1016\/j.biopsych.2011.07.017","volume":"70","author":"I Yalcin","year":"2011","unstructured":"Yalcin I, Bohren Y, Waltisperger E, Sage-Ciocca D, Yin JC, Freund-Mercier MJ, et al. A time-dependent history of mood disorders in a murine model of neuropathic pain. Biol Psychiatry. 2011;70(10):946\u201353.","journal-title":"Biol Psychiatry"},{"issue":"14","key":"150_CR40","doi-asserted-by":"publisher","first-page":"5477","DOI":"10.1523\/JNEUROSCI.0328-11.2011","volume":"31","author":"SK Kim","year":"2011","unstructured":"Kim SK, Nabekura J. Rapid synaptic remodeling in the adult somatosensory cortex following peripheral nerve injury and its association with neuropathic pain. J Neurosci. 2011;31(14):5477\u201382.","journal-title":"J Neurosci"},{"issue":"29","key":"150_CR41","doi-asserted-by":"publisher","first-page":"7445","DOI":"10.1523\/JNEUROSCI.1812-08.2008","volume":"28","author":"H Xu","year":"2008","unstructured":"Xu H, Wu LJ, Wang H, Zhang X, Vadakkan KI, Kim SS, et al. Presynaptic and postsynaptic amplifications of neuropathic pain in the anterior cingulate cortex. J Neuroscience. 2008;28(29):7445\u201353.","journal-title":"J Neuroscience"},{"key":"150_CR42","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.brainres.2011.01.006","volume":"1378","author":"CW Chou","year":"2011","unstructured":"Chou CW, Wong GT, Lim G, McCabe MF, Wang S, Irwin MG, et al. Peripheral nerve injury alters the expression of NF-kappaB in the rat\u2019s hippocampus. Brain Res. 2011;1378:66\u201371.","journal-title":"Brain Res"},{"issue":"12","key":"150_CR43","doi-asserted-by":"publisher","first-page":"2827","DOI":"10.1016\/j.pain.2011.09.013","volume":"152","author":"A Rey del","year":"2011","unstructured":"del Rey A, Yau HJ, Randolf A, Centeno MV, Wildmann J, Martina M, et al. Chronic neuropathic pain-like behavior correlates with IL-1beta expression and disrupts cytokine interactions in the hippocampus. Pain. 2011;152(12):2827\u201335.","journal-title":"Pain"},{"key":"150_CR44","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1111\/j.1749-6632.2001.tb05830.x","volume":"933","author":"BS McEwen","year":"2001","unstructured":"McEwen BS. Plasticity of the hippocampus: adaptation to chronic stress and allostatic load. Ann N Y Acad Sci. 2001;933:265\u201377.","journal-title":"Ann N Y Acad Sci"},{"issue":"2","key":"150_CR45","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1152\/jn.00763.2011","volume":"107","author":"IA Napier","year":"2012","unstructured":"Napier IA, Mohammadi SA, Christie MJ. Glutamate transporter dysfunction associated with nerve injury-induced pain in mice. J Neurophysiol. 2012;107(2):649\u201357.","journal-title":"J Neurophysiol"},{"issue":"1","key":"150_CR46","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.neuron.2009.11.031","volume":"65","author":"MS Fanselow","year":"2010","unstructured":"Fanselow MS, Dong HW. Are the dorsal and ventral hippocampus functionally distinct structures? Neuron. 2010;65(1):7\u201319.","journal-title":"Neuron"},{"issue":"1","key":"150_CR47","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.brainres.2006.09.011","volume":"1127","author":"RE McCullumsmith","year":"2007","unstructured":"McCullumsmith RE, Kristiansen LV, Beneyto M, Scarr E, Dean B, Meador-Woodruff JH. Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder. Brain Res. 2007;1127(1):108\u201318.","journal-title":"Brain Res"},{"issue":"13","key":"150_CR48","doi-asserted-by":"publisher","first-page":"2971","DOI":"10.1097\/00001756-200109170-00043","volume":"12","author":"AJ Law","year":"2001","unstructured":"Law AJ, Deakin JF. Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport. 2001;12(13):2971\u20134.","journal-title":"Neuroreport"},{"issue":"6","key":"150_CR49","doi-asserted-by":"publisher","first-page":"1636","DOI":"10.1111\/j.1471-4159.2006.03677.x","volume":"96","author":"WH Ren","year":"2006","unstructured":"Ren WH, Guo JD, Cao H, Wang H, Wang PF, Sha H, et al. Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect? J Neurochem. 2006;96(6):1636\u201347.","journal-title":"J Neurochem"},{"issue":"6","key":"150_CR50","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.1111\/j.1476-5381.2011.01680.x","volume":"165","author":"JM Lu","year":"2012","unstructured":"Lu JM, Gong N, Wang YC, Wang YX. D-Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain. Br J Pharmacol. 2012;165(6):1941\u201355.","journal-title":"Br J Pharmacol"},{"issue":"3","key":"150_CR51","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1124\/jpet.113.208363","volume":"347","author":"SR Chen","year":"2013","unstructured":"Chen SR, Zhou HY, Byun HS, Pan HL. Nerve injury increases GluA2-lacking AMPA receptor prevalence in spinal cords: functional significance and signaling mechanisms. J Pharmacol Exp Ther. 2013;347(3):765\u201372.","journal-title":"J Pharmacol Exp Ther"},{"issue":"1","key":"150_CR52","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s00441-008-0662-0","volume":"334","author":"H Willcockson","year":"2008","unstructured":"Willcockson H, Valtschanoff J. AMPA and NMDA glutamate receptors are found in both peptidergic and non-peptidergic primary afferent neurons in the rat. Cell Tissue Res. 2008;334(1):17\u201323.","journal-title":"Cell Tissue Res"},{"issue":"1","key":"150_CR53","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.neures.2006.04.015","volume":"56","author":"M Yoshimura","year":"2006","unstructured":"Yoshimura M, Yonehara N. Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain. Neurosci Res. 2006;56(1):21\u20138.","journal-title":"Neurosci Res"},{"issue":"1","key":"150_CR54","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.brainres.2006.09.059","volume":"1123","author":"J Lim","year":"2006","unstructured":"Lim J, Lim G, Sung B, Wang S, Mao J. Intrathecal midazolam regulates spinal AMPA receptor expression and function after nerve injury in rats. Brain Res. 2006;1123(1):80\u20138.","journal-title":"Brain Res"},{"key":"150_CR55","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.brainres.2008.01.012","volume":"1200","author":"Y Lu","year":"2008","unstructured":"Lu Y, Sun YN, Wu X, Sun Q, Liu FY, Xing GG, et al. Role of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit GluR1 in spinal dorsal horn in inflammatory nociception and neuropathic nociception in rat. Brain Res. 2008;1200:19\u201326.","journal-title":"Brain Res"},{"issue":"1","key":"150_CR56","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.neulet.2010.12.060","volume":"491","author":"M Miyamoto","year":"2011","unstructured":"Miyamoto M, Tsuboi Y, Takamiya K, Huganir RL, Kondo M, Shinoda M, et al. Involvement of GluR2 and GluR3 subunit C-termini in the trigeminal spinal subnucleus caudalis and C1-C2 neurons in trigeminal neuropathic pain. Neurosci Lett. 2011;491(1):8\u201312.","journal-title":"Neurosci Lett"},{"issue":"1","key":"150_CR57","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.expneurol.2007.04.006","volume":"206","author":"TJ Tseng","year":"2007","unstructured":"Tseng TJ, Hsieh YL, Hsieh ST. Reversal of ERK activation in the dorsal horn after decompression in chronic constriction injury. Exp Neurol. 2007;206(1):17\u201323.","journal-title":"Exp Neurol"},{"issue":"10","key":"150_CR58","doi-asserted-by":"publisher","first-page":"3307","DOI":"10.1523\/JNEUROSCI.4300-08.2009","volume":"29","author":"H Cao","year":"2009","unstructured":"Cao H, Gao YJ, Ren WH, Li TT, Duan KZ, Cui YH, et al. Activation of extracellular signal-regulated kinase in the anterior cingulate cortex contributes to the induction and expression of affective pain. J Neurosci. 2009;29(10):3307\u20133321.59.","journal-title":"J Neurosci"},{"key":"150_CR59","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/1744-8069-4-28","volume":"4","author":"F Wei","year":"2008","unstructured":"Wei F, Zhuo M. Activation of Erk in the anterior cingulate cortex during the induction and expression of chronic pain. Mol Pain. 2008;4:28.","journal-title":"Mol Pain"},{"issue":"3","key":"150_CR60","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1001\/jama.2010.1929","volume":"307","author":"MJ Friedrich","year":"2012","unstructured":"Friedrich MJ. Research yields new insights into mechanisms and treatment of pain. JAMA. 2012;307(3):239\u201341.","journal-title":"JAMA"},{"key":"150_CR61","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.pneurobio.2014.01.003","volume":"116","author":"MG Liu","year":"2014","unstructured":"Liu MG, Chen J. Preclinical research on pain comorbidity with affective disorders and cognitive deficits: challenges and perspectives. Prog Neurobiol. 2014;116:13\u201332.","journal-title":"Prog Neurobiol"},{"issue":"4","key":"150_CR62","doi-asserted-by":"publisher","first-page":"394","DOI":"10.4161\/cib.15694","volume":"4","author":"MY Min","year":"2011","unstructured":"Min MY, Yang HW, Yen CT, Chen CC, Cheng SJ. ERK, synaptic plasticity and acid-induced muscle pain. Comm Integrative Biol. 2011;4(4):394\u20136.","journal-title":"Comm Integrative Biol"},{"key":"150_CR63","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.brainres.2011.01.076","volume":"1382","author":"MG Liu","year":"2011","unstructured":"Liu MG, Wang RR, Chen XF, Zhang FK, Cui XY, Chen J. Differential roles of ERK, JNK and p38 MAPK in pain-related spatial and temporal enhancement of synaptic responses in the hippocampal formation of rats: multi-electrode array recordings. Brain Res. 2011;1382:57\u201369.","journal-title":"Brain Res"},{"issue":"3","key":"150_CR64","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.neuroscience.2008.08.002","volume":"156","author":"YJ Seo","year":"2008","unstructured":"Seo YJ, Kwon MS, Choi HW, Choi SM, Kim YW, Lee JK, et al. Differential expression of phosphorylated Ca2+\/calmodulin-dependent protein kinase II and phosphorylated extracellular signal-regulated protein in the mouse hippocampus induced by various nociceptive stimuli. Neuroscience. 2008;156(3):436\u201349.","journal-title":"Neuroscience"},{"issue":"1","key":"150_CR65","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s12264-012-1060-x","volume":"28","author":"H Cao","year":"2012","unstructured":"Cao H, Ren WH, Zhu MY, Zhao ZQ, Zhang YQ. Activation of glycine site and GluN2B subunit of NMDA receptors is necessary for ERK\/CREB signaling cascade in rostral anterior cingulate cortex in rats: implications for affective pain. Neurosci Bull. 2012;28(1):77\u201387.","journal-title":"Neurosci Bull"}],"container-title":["BMC Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12868-015-0150-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12868-015-0150-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12868-015-0150-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12868-015-0150-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,26]],"date-time":"2019-02-26T12:43:33Z","timestamp":1551185013000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcneurosci.biomedcentral.com\/articles\/10.1186\/s12868-015-0150-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,14]]},"references-count":65,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["150"],"URL":"https:\/\/doi.org\/10.1186\/s12868-015-0150-x","relation":{},"ISSN":["1471-2202"],"issn-type":[{"value":"1471-2202","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,14]]},"assertion":[{"value":"16 October 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 February 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 March 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}],"article-number":"14"}}