{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:05:38Z","timestamp":1793318738561,"version":"4.5.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Anesthesiol"],"published-print":{"date-parts":[[2017,12]]},"DOI":"10.1186\/s12871-017-0380-9","type":"journal-article","created":{"date-parts":[[2017,6,28]],"date-time":"2017-06-28T08:53:04Z","timestamp":1498639984000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":133,"title":["General vs. neuraxial anaesthesia in hip fracture patients: a systematic review and meta-analysis"],"prefix":"10.1186","volume":"17","author":[{"given":"Julia","family":"Van Waesberghe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Stevanovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Rossaint","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7930-0270","authenticated-orcid":false,"given":"Mark","family":"Coburn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,6,28]]},"reference":[{"key":"380_CR1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4103\/0019-5413.73656","volume":"45","author":"DK Dhanwal","year":"2011","unstructured":"Dhanwal DK, Dennison EM, Harvey NC, Cooper C. Epidemiology of hip fracture: worldwide geographic variation. Indian J Orthop. 2011;45:15\u201322.","journal-title":"Indian J Orthop"},{"key":"380_CR2","doi-asserted-by":"crossref","first-page":"380","DOI":"10.7326\/0003-4819-152-6-201003160-00008","volume":"152","author":"P Haentjens","year":"2010","unstructured":"Haentjens P, Magaziner J, Colon-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B, et al. Meta-analysis: excess mortality after hip fracture among old women and men. Ann Intern Med. 2010;152:380\u201390.","journal-title":"Ann Intern Med"},{"key":"380_CR3","volume-title":"National hip Fracture Database (NHFD) annual report 2015","author":"Royal College of Physicians","year":"2015","unstructured":"Royal College of Physicians. National hip Fracture Database (NHFD) annual report 2015. London: RCP; 2015."},{"key":"380_CR4","doi-asserted-by":"crossref","unstructured":"Johnell O, Kanis JA. An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int. 2006:17:1726\u201333.","DOI":"10.1007\/s00198-006-0172-4"},{"key":"380_CR5","unstructured":"Association of Anaesthetists of Great Britain and Ireland, Griffiths R, Alper J, Beckingsale A, Goldhill D, Heyburn G, et al. Management of proximal femoral fractures 2011: Association of Anaesthetists of Great Britain and Ireland. Anaesthesia. 2012:6785\u201398."},{"key":"380_CR6","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/hec.3278","volume":"24","author":"E Medin","year":"2015","unstructured":"Medin E, Goude F, Melberg HO, Tediosi F, Belicza E, Peltola M, et al. European regional differences in all-cause mortality and length of stay for hip fracture patients [abstract]. Health Econ. 2015;24:53\u201364.","journal-title":"Health Econ"},{"key":"380_CR7","doi-asserted-by":"publisher","unstructured":"Guay J, Parker MJ, Gajendragadkar PR, Kopp S. Anaesthesia for hip fracture surgery in adults. Cochrane Database of Systematic Reviews 2016, Issue 2. Art. No.: CD000521. DOI: 10.1002\/14651858.CD000521","DOI":"10.1002\/14651858.CD000521"},{"key":"380_CR8","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1302\/0301-620X.97B5.35042","volume":"97-B","author":"BA Basques","year":"2015","unstructured":"Basques BA, Bohl DD, Golinvaux NS, Samuel AM, Grauer JG. General versus spinal anaesthesia for patients aged 70 years and older with a fracture of the hip. Bone joint J. 2015;97-B:689\u201395.","journal-title":"Bone joint J"},{"key":"380_CR9","doi-asserted-by":"crossref","unstructured":"Fields AC, Dietrich JD, Buterbaugh K, Moucha CS. Short-term complications in hip fracture surgery using spinal versus general anesthesia. Injury. 2015:46719\u201323.","DOI":"10.1016\/j.injury.2015.02.002"},{"key":"380_CR10","doi-asserted-by":"crossref","first-page":"186","DOI":"10.2106\/JBJS.N.00612","volume":"97","author":"MH Helwani","year":"2015","unstructured":"Helwani MH, Avidan MS, Ben Abdallah A, Kaiser DJ, Clohisy JC, Hall BL, et al. Effects of regional versus general anesthesia on outcomes after total hip arthroplasty. J Bone Joint Surg Am. 2015;97:186\u201393.","journal-title":"J Bone Joint Surg Am"},{"key":"380_CR11","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ijsu.2015.11.009","volume":"24","author":"G Karademir","year":"2015","unstructured":"Karademir G, Bilgin Y, Ersen A, Polat G, Buget MI, Demirel M, et al. Hip fractures in patients older than 75 years old: retrospective analysis for prognostic factors. Int J Surg. 2015;24:101\u20134.","journal-title":"Int J Surg"},{"key":"380_CR12","doi-asserted-by":"crossref","first-page":"44","DOI":"10.5505\/tjtes.2015.02582","volume":"21","author":"\u00d6 Karaman","year":"2015","unstructured":"Karaman \u00d6, \u00d6zkazanli G, Orak MM, Mutlu H, Caliskan G, Karakus \u00d6, et al. Factors affecting postoperative mortality in patients older than 65 years undergoing surgery for hip fracture. Ulus Travma Acil Cerrahi Derq. 2015;21:44\u201350.","journal-title":"Ulus Travma Acil Cerrahi Derq"},{"key":"380_CR13","doi-asserted-by":"crossref","first-page":"505","DOI":"10.4097\/kjae.2013.64.6.505","volume":"64","author":"SD Kim","year":"2013","unstructured":"Kim SD, Park SJ, Lee DH, Jee DL. Risk factors of morbidity and mortality following hip fracture surgery. Korean J Anesthesiol. 2013;64:505\u201310.","journal-title":"Korean J Anesthesiol"},{"key":"380_CR14","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1111\/j.1526-4637.2012.01402.x","volume":"13","author":"L Le-Wendling","year":"2012","unstructured":"Le-Wendling L, Bihorac A, Baslanti TO, Lucas S, Sadasivan K, Wendling A, et al. Regional anesthesia as compared with general anesthesia for surgery in geriatric patients with hip fracture: does it decrease morbidity, mortality, and health care costs? Results of a single-centered study. Pain Med. 2012;13:948\u201356.","journal-title":"Pain Med"},{"issue":"311","key":"380_CR15","doi-asserted-by":"crossref","first-page":"2508","DOI":"10.1001\/jama.2014.6499","volume":"25","author":"MD Neuman","year":"2014","unstructured":"Neuman MD, Rosenbaum PR, Ludwiq JM, Zubizarreta JR, Silber JH. Anesthesia technique, mortality, and length of stay after hip fracture surgery. JAMA. 2014;25(311):2508\u201317.","journal-title":"JAMA"},{"key":"380_CR16","doi-asserted-by":"crossref","first-page":"g4022","DOI":"10.1136\/bmj.g4022","volume":"348","author":"E Patorno","year":"2014","unstructured":"Patorno E, Neumann MD, Schneeweiss S, Mogun H, Bateman BT. Comparative safety of anesthetic type for hip fracture surgery in adults: retrospective cohort study. BMJ. 2014;348:g4022.","journal-title":"BMJ"},{"key":"380_CR17","doi-asserted-by":"publisher","unstructured":"Rashid RH, Shah AA, Shakoor A, Noordin S. Hip fracture surgery: does type of anesthesia matter? Biomed Res Int. Volume 2013 doi: 10.1155\/2013\/252356","DOI":"10.1155\/2013\/252356"},{"key":"380_CR18","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S1873-9598(10)70020-X","volume":"4","author":"Y-J Shih","year":"2010","unstructured":"Shih Y-J, Hsieh C-H, Kang T-W, Peng S-Y, Fan K-T, Wang L-M, et al. General versus spinal anesthesia: which is a risk factor for octogenarian hip fracture repair patients? Int J Gerontol. 2010;4:37\u201342.","journal-title":"Int J Gerontol"},{"key":"380_CR19","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1111\/jgs.13106","volume":"62","author":"DP Seitz","year":"2014","unstructured":"Seitz DP, Gill SS, Bell CM, Austin PC, Anderson GM, et al. A postoperative medical complications associated with anesthesia on older adults with dementia. J Am Geriatr Soc. 2014;62:2102\u20139.","journal-title":"J Am Geriatr Soc"},{"key":"380_CR20","doi-asserted-by":"crossref","first-page":"623","DOI":"10.5336\/medsci.2011-23901","volume":"32","author":"HS Sevtap","year":"2012","unstructured":"Sevtap HS, Nurettin H, Alkin C, Necdet S. Comparison of different anesthetic techniques on postoperative outcomes in elderly patients with hip fracture. Turkiye Klinikleri J Med Sci. 2012;32:623\u20139.","journal-title":"Turkiye Klinikleri J Med Sci"},{"key":"380_CR21","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1111\/anae.12542","volume":"69","author":"SM White","year":"2014","unstructured":"White SM, Moppett IK, Griffiths R. Outcome by mode of anaesthesia for hip fracture surgery. An observational audit of 65 535 patients in a national dataset. Anaesthesia. 2014;69:224\u201330.","journal-title":"Anaesthesia"},{"key":"380_CR22","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1007\/s00264-015-2735-5","volume":"39","author":"PS Whiting","year":"2015","unstructured":"Whiting PS, Molina CS, Greenberg SE, Thakore RV, Obremskey WT, Sethi MK. Regional Anaesthesia for hip fracture surgery is associated with significantly more peri-operative complications compared with general anaesthesia. Int Orthop. 2015;39:1321\u20137.","journal-title":"Int Orthop"},{"key":"380_CR23","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3109\/17453674.2015.1128781","volume":"87","author":"WT Brox","year":"2016","unstructured":"Brox WT, Chan PH, Cafri G, Inacio MC. Similar mortality with general or regional anesthesia in elderly hip fracture patients. Acta Orthop. 2016;87:152\u20137.","journal-title":"Acta Orthop"},{"key":"380_CR24","doi-asserted-by":"crossref","first-page":"e3296","DOI":"10.1097\/MD.0000000000003296","volume":"95","author":"Y-C Tung","year":"2016","unstructured":"Tung Y-C, Hsu Y-H, Chang G-M. The effect of anesthetic type on outcomes of hip fracture surgery. Medicine (Baltimore). 2016;95:e3296.","journal-title":"Medicine (Baltimore)"},{"key":"380_CR25","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1097\/ALN.0000000000000695","volume":"123","author":"CC Chu","year":"2015","unstructured":"Chu CC, Weng SF, Chen KT, Chien CC, Shieh JP, Chen JY, et al. Propensity score-matched comparison of postoperative adverse outcomes between geriatric patients given a general or a neuraxial anesthetic for hip surgery: a population-based study. Anesthesiology. 2015;123:136\u201347.","journal-title":"Anesthesiology"},{"key":"380_CR26","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/anae.13415","volume":"71","author":"SM White","year":"2016","unstructured":"White SM, Moppett IK, Griffiths R, Johansen A, Wakeman R, Boulton C, et al. Secondary analysis of outcomes after 11,085 hip fracture operations from the prospective UK Anaesthesia Sprint audit of practice (ASAP-2). Anaesthesia. 2016;71:506\u201314.","journal-title":"Anaesthesia"},{"key":"380_CR27","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/ALN.0b013e3182545e7c","volume":"117","author":"MD Neuman","year":"2012","unstructured":"Neuman MD, Silber JH, Elkassabany NM. Comparative effectiveness of regional versus general anesthesia for hip fracture surgery in adults. Anesthesiology. 2012;117:72\u201392.","journal-title":"Anesthesiology"},{"key":"380_CR28","doi-asserted-by":"crossref","first-page":"b2700","DOI":"10.1136\/bmj.b2700","volume":"339","author":"A Liberati","year":"2009","unstructured":"Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotsche P, Ioannidis JPA, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ. 2009;339:b2700.","journal-title":"BMJ"},{"key":"380_CR29","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1097\/BOT.0000000000000222","volume":"29","author":"BA Basques","year":"2015","unstructured":"Basques BA, Bohl DD, Golinvaux NS, Leslie MP, Baumgartner MR, Grauer JN. Postoperative length of stay and 30-day readmission after geriatric hip fracture: an analysis of 8434 patients. J Orthop Trauma. 2015;29:115\u201320.","journal-title":"J Orthop Trauma"},{"key":"380_CR30","first-page":"2789","volume":"8","author":"P Zhao","year":"2015","unstructured":"Zhao P, Lian X, Dou X, Bi Q, Quan R, Tong P, et al. Intertrochanteric hip fracture surgery in Chinese: risk factors for predicting mortality. Int J Clin Exp Med. 2015;8:2789\u201393.","journal-title":"Int J Clin Exp Med"},{"key":"380_CR31","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1016\/j.injury.2015.05.004","volume":"48","author":"MJ Parker","year":"2015","unstructured":"Parker MJ, Griffiths R. General versus regional anaesthesia for hip fractures. A pilot randomised controlled trial of 322 patients. Injury. 2015;48:1562\u20136.","journal-title":"Injury"},{"key":"380_CR32","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/AAP.0b013e318252e901","volume":"37","author":"P Biboulet","year":"2012","unstructured":"Biboulet P, Jourdan A, Van Haevre V, Morau D, Bernard N, Brinquier S, et al. Hemodynamic profile of target-controlled spinal anesthesia compared with 2 target-controlled general anesthesia techniques in elderly patients with cardiac comorbidities. Reg Anesth Pain Med. 2012;37:433\u201340.","journal-title":"Reg Anesth Pain Med"},{"key":"380_CR33","first-page":"323","volume":"16","author":"SA Heidari","year":"2011","unstructured":"Heidari SA, Soltani H, Hashemi SJ, Talakoub R, Soleimani B. Comparative study of two anesthesia methods according to postoperative complications and one month mortality rate in the candidates of hip surgery. J Res Med Sci. 2011;16:323\u201330.","journal-title":"J Res Med Sci"},{"key":"380_CR34","doi-asserted-by":"crossref","unstructured":"Luger TJ, Kammerlander C, Gosch M, Luger MF, Kammerlander-Knauer U, Roth T et al. Neuroaxial versus general anaesthesia in geriatric patients for hip fracture surgery: does it matter [abstract]? Osteoporos Int. 2010.; 21S555-72.","DOI":"10.1007\/s00198-010-1399-7"},{"key":"380_CR35","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.injury.2013.11.020","volume":"45","author":"GH Kazemian","year":"2014","unstructured":"Kazemian GH, Manafi AR, Najafi F, Najafi MA. Treatment of intertrochanteric fractures in elderly high risk patients: dynamic hip screw vs. external fixation. Injury. 2014;45:568\u201372.","journal-title":"Injury"},{"key":"380_CR36","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1093\/gerona\/58.11.M1042","volume":"58","author":"HK Kamel","year":"2003","unstructured":"Kamel HK, Iqbal MA, Mogallapu R, Maas D, Hoffmann RG. Time to ambulation after hip fracture surgery: relation to hospitalization outcomes. J Gerontol A Biol Sci Med Sci. 2003;58:1042\u20135.","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"380_CR37","unstructured":"American College of Surgeons National Surgical Quality Improvement Program\u00ae (ACS NSQIP\u00ae) available from https:\/\/www.facs.org\/quality-programs\/acs-nsqip"},{"key":"380_CR38","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/S0140-6736(17)30066-1","volume":"389","author":"Fixation using Alternative Implants for the treatment of Hip fractures (FAITH) Investigators","year":"2017","unstructured":"Fixation using Alternative Implants for the treatment of Hip fractures (FAITH) Investigators. Fracture fixation in the operative management of hip fractures (FAITH): an international, multicentre, randomised controlled trial. Lancet. 2017;389:1519\u201327.","journal-title":"Lancet"},{"key":"380_CR39","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.redar.2014.07.001","volume":"61","author":"CL Errando","year":"2014","unstructured":"Errando CL, Soriano-Bru JL, Peiro CM, Ubeda J. Single shot spinal anaesthesia with hypobaric bupivacaine for hip fracture repair surgery in the elderly. Randomize, double blinded comparison of 3.75 mg vs. 7.5 mg. Rev Esp Anestesiol Reanim. 2014;61:541\u20138.","journal-title":"Rev Esp Anestesiol Reanim"}],"container-title":["BMC Anesthesiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12871-017-0380-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,27]],"date-time":"2019-09-27T05:42:19Z","timestamp":1569562939000},"score":1,"resource":{"primary":{"URL":"http:\/\/bmcanesthesiol.biomedcentral.com\/articles\/10.1186\/s12871-017-0380-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,28]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["380"],"URL":"https:\/\/doi.org\/10.1186\/s12871-017-0380-9","relation":{},"ISSN":["1471-2253"],"issn-type":[{"value":"1471-2253","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,28]]},"article-number":"87"}}