{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:43:29Z","timestamp":1790750609939,"version":"4.1.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,3,9]],"date-time":"2019-03-09T00:00:00Z","timestamp":1552089600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Anesthesiol"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12871-019-0707-9","type":"journal-article","created":{"date-parts":[[2019,3,9]],"date-time":"2019-03-09T10:02:44Z","timestamp":1552125764000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Pleth variability index versus pulse pressure variation for intraoperative goal-directed fluid therapy in patients undergoing low-to-moderate risk abdominal surgery: a randomized controlled trial"],"prefix":"10.1186","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3478-0696","authenticated-orcid":false,"given":"Sean","family":"Coeckelenbergh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9lie","family":"Delaporte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djamal","family":"Ghoundiwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javad","family":"Bidgoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Fils","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Schmartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Van der Linden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,3,9]]},"reference":[{"issue":"5","key":"707_CR1","doi-asserted-by":"publisher","first-page":"R191","DOI":"10.1186\/cc12885","volume":"17","author":"C Salzwedel","year":"2013","unstructured":"Salzwedel C, Puig J, Carstens A, Bein B, Molnar Z, Kiss K, Hussain A, Belda J, Kirov MY, Sakka SG, Reuter DA. Perioperative goal-directed hemodynamic therapy based on radial arterial pulse pressure variation and continuous cardiac index trending reduces postoperative complications after major abdominal surgery: a multi-center, prospective, randomized study. Crit Care. 2013;17(5):R191.","journal-title":"Crit Care"},{"issue":"9","key":"707_CR2","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1097\/EJA.0000000000000827","volume":"35","author":"A Joosten","year":"2018","unstructured":"Joosten A, Coeckelenbergh S, Delaporte A, Ickx B, Closset J, Roumeguere T, Barvais L, Van Obbergh L, Cannesson M, Rinehart J, Van der Linden P. Implementation of closed-loop-assisted intra-operative goal-directed fluid therapy during major abdominal surgery: a case-control study with propensity matching. Eur J Anaesthesiol. 2018;35(9):650\u20138.","journal-title":"Eur J Anaesthesiol"},{"issue":"21","key":"707_CR3","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.1001\/jama.2014.5305","volume":"311","author":"RM Pearse","year":"2014","unstructured":"Pearse RM, Harrison DA, MacDonald N, Gillies MA, et al. Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review. JAMA. 2014;311(21):2181\u201390.","journal-title":"JAMA."},{"issue":"6","key":"707_CR4","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1007\/s10877-015-9821-5","volume":"30","author":"S Lee","year":"2016","unstructured":"Lee S, Chun Y, Oh Y, Shin S, Park S, Kim S, Choi Y. Prediction of fluid responsiveness in the beach chair position using dynamic preload indices. J Clin Monit Comput. 2016;30(6):995\u20131002.","journal-title":"J Clin Monit Comput"},{"issue":"9","key":"707_CR5","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1097\/EJA.0000000000000479","volume":"33","author":"C Wu","year":"2016","unstructured":"Wu C, Cheng Y, Liu Y, Wu T, Chien C, Chan K. Predicting stroke volume and arterial pressure fluid responsiveness in liver cirrhosis patients using dynamic preload variables: a prospective study of diagnostic accuracy. Eur J Anaesthesiol. 2016;33(9):645\u201352.","journal-title":"Eur J Anaesthesiol"},{"issue":"6","key":"707_CR6","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1093\/bja\/aes508","volume":"110","author":"JJ Vos","year":"2013","unstructured":"Vos JJ, Kalmar AF, Struys MM, Wietasch JK, Hendriks HG, Scheeren TW. Comparison of arterial pressure and plethysmographic waveform-based dynamic preload variables in assessing fluid responsiveness and dynamic arterial tone in patients undergoing major hepatic resection. Br J Anaesth. 2013;110(6):940\u20136.","journal-title":"Br J Anaesth"},{"key":"707_CR7","doi-asserted-by":"publisher","first-page":"386","DOI":"10.12659\/MSM.890073","volume":"20","author":"W Lu","year":"2014","unstructured":"Lu W, Dong J, Xu Z, Shen H, Zheng J. The pleth variability index as an indicator of the central extracellular fluid volume in mechanically ventilated patients after anesthesia induction: comparison with initial distribution volume of glucose. Med Sci Monit. 2014;20:386\u201392.","journal-title":"Med Sci Monit"},{"issue":"1","key":"707_CR8","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s12871-017-0316-4","volume":"17","author":"EN Zee van der","year":"2017","unstructured":"van der Zee EN, Egal M, Gommers D, Groeneveld AB. Targeting urine output and 30-day mortality in goal-directed therapy: a systematic review with meta-analysis and meta-regression. BMC Anesthesiol. 2017;17(1):22.","journal-title":"BMC Anesthesiol"},{"issue":"5","key":"707_CR9","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1186\/s13054-014-0584-z","volume":"18","author":"J Benes","year":"2014","unstructured":"Benes J, Giglio M, Brienza N, Michard F. The effects of goal-directed fluid therapy based on dynamic parameters on post-surgical outcome: a meta-analysis of randomized controlled trials. Crit Care. 2014;18(5):584.","journal-title":"Crit Care"},{"issue":"3","key":"707_CR10","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1186\/cc1489","volume":"6","author":"B Scheer","year":"2002","unstructured":"Scheer B, Perel A, Pfeiffer UJ. Clinical review: complications and risk factors of peripheral arterial catheters used for haemodynamic monitoring in anaesthesia and intensive care medicine. Crit Care. 2002;6(3):199\u2013204.","journal-title":"Crit Care"},{"issue":"2","key":"707_CR11","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1093\/bja\/aen133","volume":"101","author":"M Cannesson","year":"2008","unstructured":"Cannesson M, Desebbe O, Rosamel P, Delannoy B, et al. Pleth variability index to monitor the respiratory variations in the pulse oximeter plethysmographic waveform amplitude and predict fluid responsiveness in the operating theatre. Br J Anaesth. 2008;101(2):200\u20136.","journal-title":"Br J Anaesth"},{"issue":"4","key":"707_CR12","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1213\/ANE.0b013e3181eb624f","volume":"111","author":"P Forget","year":"2010","unstructured":"Forget P, Lois F, de Kock M. Goal-directed fluid management based on the pulse oximeter-derived pleth variability index reduces lactate levels and improve fluid management. Anesth Analg. 2010;111(4):910\u20134.","journal-title":"Anesth Analg"},{"key":"707_CR13","doi-asserted-by":"crossref","unstructured":"Cesur S, \u00c7ardak\u00f6z\u00fc T, Ku\u015f A, T\u00fcrky\u0131lmaz N, Yavuz \u00d6. Comparison of conventional fluid management with PVI-based goal directed fluid management in elective colorectal surgery. J Clin Monit Comput. 2018; [Epub ahead of print].","DOI":"10.1007\/s10877-018-0163-y"},{"key":"707_CR14","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.jamcollsurg.2014.12.042","volume":"220","author":"RH Thiele","year":"2015","unstructured":"Thiele RH, Rea KM, Turrentine FE, Friel CM, Hassinger TE, McMurry TL, Goudreau BJ, Umapathi BA, Kron IL, Sawyer RG, et al. Standardization of care: impact of an enhanced recovery protocol on length of stay, complications, and direct 30 costs after colorectal surgery. J Am Coll Surg. 2015;220:430\u201343.","journal-title":"J Am Coll Surg"},{"issue":"5","key":"707_CR15","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1097\/ALN.0b013e3182700901","volume":"117","author":"B Hengy","year":"2012","unstructured":"Hengy B, Gazon M, Schmitt Z, Benyoub K, et al. Comparison between respiratory variations in pulse oximetry plethysmographic waveform amplitude and arterial pulse pressure during major abdominal surgery. Anesthesiology. 2012;117(5):973\u201380.","journal-title":"Anesthesiology."},{"issue":"1","key":"707_CR16","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/s12871-018-0520-x","volume":"18","author":"MT Ganter","year":"2018","unstructured":"Ganter MT, Geisen M, Hartnack S, Dzemali O, Hofer CK. Prediction of fluid responsiveness in mechanically ventilated cardiac surgical patients: the performance of seven different functional hemodynamic parameters. BMC Anesthesiol. 2018;18(1):55.","journal-title":"BMC Anesthesiol"},{"issue":"6","key":"707_CR17","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1097\/00000542-199512000-00010","volume":"83","author":"E Gepts","year":"1995","unstructured":"Gepts E, Shafer S, Camu F, Stanski D, Woestenborghs R, Van Peer A, Heykants J. Linearity of pharmacokinetics and model estimation of Sufentanil. Anesthesiology. 1995;83(6):1194\u2013204.","journal-title":"Anesthesiology"},{"issue":"21","key":"707_CR18","first-page":"1628","volume":"48","author":"QF Cai","year":"2010","unstructured":"Cai QF, Mi WD, Yuan WX. The ability of pleth variability index to predict fluid responsiveness in mechanically ventilated patients under general anaesthesia. Zhonghua Wai Ke Za Zhi. 2010;48(21):1628\u201332.","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"707_CR19","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1186\/s12871-015-0131-8","volume":"15","author":"J Benes","year":"2015","unstructured":"Benes J, Haidingerova L, Pouska J, Stepanik J, Stenglova A, Zatloukal J, Pradl R, Chytra I, Kasal E. Fluid management guided by a continuous non-invasive arterial pressure device is associated with decreased postoperative morbidity after total knee and hip replacement. BMC Anesthesiol. 2015;15:148.","journal-title":"BMC Anesthesiol"},{"key":"707_CR20","volume-title":"Sample Size Calculations in Clinical Research","author":"S Chow","year":"2008","unstructured":"Chow S, Shao J, Wang H. Sample Size Calculations in Clinical Research. 2nd ed. New York: Marcel Dekker; 2008.","edition":"2"},{"key":"707_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18637\/jss.v064.i09","volume":"64","author":"F Konietschke","year":"2015","unstructured":"Konietschke F, Placzek M, Schaarschmidt F, et al. Nparcomp:an R software package for nonparametric multiple comparisons and simultaneous confidence intervals. J Stat Softw. 2015;64:1\u201317.","journal-title":"J Stat Softw"},{"issue":"1","key":"707_CR22","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1002\/(SICI)1521-4036(200001)42:1<17::AID-BIMJ17>3.0.CO;2-U","volume":"1","author":"E Brunner","year":"2000","unstructured":"Brunner E, Munzel U. The nonparametric Behrens-fisher problem: asymptotic theory and a small-sample approximation. Biom J. 2000;1(1):17\u201321.","journal-title":"Biom J"},{"issue":"2","key":"707_CR23","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1007\/s11695-017-2840-1","volume":"28","author":"\u0130 Demirel","year":"2018","unstructured":"Demirel \u0130, Bolat E, Altun AY, \u00d6zdemir M, Be\u015fta\u015f A. Efficacy of goal-directed fluid therapy via Pleth variability index during laparoscopic roux-en-Y gastric bypass surgery in morbidly obese patients. Obes Surg. 2018;28(2):358\u201363.","journal-title":"Obes Surg"},{"key":"707_CR24","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s10877-014-9567-5","volume":"29","author":"Y Yu","year":"2015","unstructured":"Yu Y, Dong J, Xu Z, Shen H, Zheng J. Pleth variability index-directed fluid management in abdominal surgery under combined general and epidural anesthesia. J Clin Monit Comput. 2015;29:47\u201352.","journal-title":"J Clin Monit Comput"},{"key":"707_CR25","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1097\/MD.0000000000010723","volume":"97","author":"M Guen Le","year":"2018","unstructured":"Le Guen M, MD FA, Gayat E, Fischler M. The plethysmographic variability index does not predict fluid responsiveness estimated by esophageal Doppler during kidney transplantation a controlled study. Medicine. 2018;97:20.","journal-title":"Medicine"},{"key":"707_CR26","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1023\/A:1007361020825","volume":"13","author":"KH Shelley","year":"1997","unstructured":"Shelley KH, Murray WB, Chang D. Arterial-pulse oximetry loops: a new method of monitoring vascular tone. J Clin Monit. 1997;13:223\u20138.","journal-title":"J Clin Monit"},{"key":"707_CR27","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1016\/j.jclinane.2016.06.033","volume":"34","author":"S Warnakulasuriya","year":"2016","unstructured":"Warnakulasuriya S, Davies S, Wilson R, Yates D. Comparison of esophageal Doppler and plethysmographic variability index to guide intraoperative fluid therapy for low-risk patients undergoing colorectal surgery. J Clin Anesth. 2016;34:600\u20138.","journal-title":"J Clin Anesth"},{"issue":"1","key":"707_CR28","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1186\/s12871-018-0579-4","volume":"18","author":"H Bahlmann","year":"2018","unstructured":"Bahlmann H, Hahn RG, Nilsson L. Pleth variability index or stroke volume optimization during open abdominal surgery: a randomized controlled trial. BMC Anesthesiol. 2018;18(1):115.","journal-title":"BMC Anesthesiol"},{"key":"707_CR29","doi-asserted-by":"crossref","unstructured":"Joosten A, Raj Lawrence S, Colesnicenco A, Coeckelenbergh S, Vincent JL, Van der Linden P, Cannesson M, Rinehart J. Personalized versus Protocolized fluid management using noninvasive hemodynamic monitoring (Clearsight system) in patients undergoing moderate-risk abdominal surgery. Anesth Analg. 2018; [Epub ahead of print].","DOI":"10.1213\/ANE.0000000000003553"},{"issue":"9","key":"707_CR30","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.1111\/anae.13834","volume":"72","author":"J Stens","year":"2017","unstructured":"Stens J, Hering JP, van der Hoeven CWP, Boom A, et al. The added value of cardiac index and pulse pressure variation monitoring to mean arterial pressure-guided volume therapy in moderate-risk abdominal surgery (COGUIDE): a pragmatic multicentre randomised controlled trial. Anaesthesia. 2017;72(9):1078\u201387.","journal-title":"Anaesthesia."},{"issue":"4","key":"707_CR31","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1093\/bja\/aem211","volume":"99","author":"K Holte","year":"2007","unstructured":"Holte K, Foss NB, Andersen J, Valentiner L, et al. Liberal or restrictive fluid administration in fast-track colonic surgery: a randomized, double-blind study. Br J Anaesth. 2007;99(4):500\u20138.","journal-title":"Br J Anaesth"},{"key":"707_CR32","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1111\/j.1399-6576.2011.02435.x","volume":"55","author":"O Broch","year":"2011","unstructured":"Broch O, Bein B, Gruenewald M, H\u00f6cker J, Sch\u00f6ttler J, Meybohm P, Steinfath M, Renner J. Accuracy of the pleth variability index to predict fluid responsiveness depends on the perfusion index. Acta Anaesthesiol Scand. 2011;55:686\u201393.","journal-title":"Acta Anaesthesiol Scand"}],"container-title":["BMC Anesthesiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12871-019-0707-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12871-019-0707-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12871-019-0707-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T15:59:07Z","timestamp":1663084747000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcanesthesiol.biomedcentral.com\/articles\/10.1186\/s12871-019-0707-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,9]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["707"],"URL":"https:\/\/doi.org\/10.1186\/s12871-019-0707-9","relation":{},"ISSN":["1471-2253"],"issn-type":[{"value":"1471-2253","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,9]]},"assertion":[{"value":"10 September 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was approved by the CHU Brugmann ethical committee and patients gave written informed consent.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"not applicable","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"34"}}