{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T11:45:55Z","timestamp":1649159155660},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:00:00Z","timestamp":1612310400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T00:00:00Z","timestamp":1612310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Anesthesiol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>The insertion of inappropriately sized uncuffed endotracheal tubes (ETTs) with a tight seal or presence of air leakage may be necessary in children. This study aimed to analyze the frequency of the requirement of inappropriately sized uncuffed ETT insertion, air leakage after the ETT was replaced with one of a larger size, and factors associated with air leakage after ETT replacement.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Patients under 2\u2009years of age who underwent oral surgery under general anesthesia with uncuffed ETTs between December 2013 and May 2015 were enrolled. The ETT size was selected at the discretion of the attending anesthesiologists. A leak test was performed after intubation. The ETT was replaced when considered necessary. Data regarding the leak pressure (P<jats:sub>Leak<\/jats:sub>) and inspiratory and expiratory tidal volumes were extracted from anesthesia records. We considered a P<jats:sub>Leak<\/jats:sub> of 10\u2009&lt;\u2009P<jats:sub>Leak<\/jats:sub>\u2009\u2264\u200930 cmH<jats:sub>2<\/jats:sub>O to be appropriate. The frequencies of the requirement of inappropriately sized ETTs, absence of leakage after ETT replacement, ETT size difference, and leak rate were calculated. A logistic regression was performed, with P<jats:sub>Leak<\/jats:sub>, leak rate, and size difference included as explanatory variables and presence of leakage after replacement as the outcome variable.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Out of the 156 patients enrolled, 109 underwent ETT replacement, with the requirement of inappropriately sized ETTs being observed in 25 patients (23%). ETT replacement was performed in patients with P<jats:sub>Leak<\/jats:sub>\u2009\u2264\u200910 cmH<jats:sub>2<\/jats:sub>O; leakage was absent after replacement (P<jats:sub>Leak<\/jats:sub>\u2009&lt;\u200930 cmH<jats:sub>2<\/jats:sub>O) in 52% of patients (25\/48). In the multivariate logistic model, the leak rate before ETT replacement was significantly associated with the presence of leakage after replacement (<jats:italic>p<\/jats:italic>\u2009=\u20090.021).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Inappropriately sized ETTs were inserted in approximately 23% of the patients. The leak rate may be useful to guide ETT replacement.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12871-021-01258-0","type":"journal-article","created":{"date-parts":[[2021,2,3]],"date-time":"2021-02-03T06:03:03Z","timestamp":1612332183000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Frequency of the requirement of inappropriate uncuffed tracheal tube size for pediatric patients: a retrospective observational analysis"],"prefix":"10.1186","volume":"21","author":[{"given":"Hiroshi","family":"Hanamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hikaru","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Niwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,3]]},"reference":[{"key":"1258_CR1","first-page":"311","volume-title":"A practice of anesthesia for infants and children","author":"CJ Cote","year":"2019","unstructured":"Cote CJ, Lerman J, Anderson BJ. 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The requirement for written informed consent was waived by the Ethics Committee of Osaka University Graduate School of Dentistry because of the retrospective nature of the study. Further, all methods performed in the study adhered to the tenets of Declaration of Helsinki, and the patient data were anonymized for the retrospective analysis.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"34"}}