{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T09:17:45Z","timestamp":1794043065539,"version":"4.8.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Anesthesiol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Enhanced recovery after surgery (ERAS) pathways have been shown to improve clinical outcomes after surgery. Considering the importance of patient experience for patients with benign surgery, this study evaluated whether improved compliance with ERAS protocol modified for gynecological surgery which recommended by the ERAS Society is associated with better clinical outcomes and patient experience, and to determine the influence of compliance with each ERAS element on patients\u2019 outcome after benign hysterectomy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A prospective observational study was performed on the women who underwent hysterectomy between 2019 and 2020. A total of 475 women greater 18\u2009years old were classified into three groups according to their per cent compliance with ERAS protocols: Group I: &lt;\u200960% (148 cases); Group II:\u226560 and\u2009&lt;\u200980% (160 cases); Group III: \u226580% (167 cases). Primary outcome was the 30-day postoperative complications. Second outcomes included QoR-15 questionnaire scores, patient satisfaction on a scale from 1 to 7, and length of stay after operation. After multivariable binary logistic regression analyse, a nomogram model was established to predict the incidence of having a postoperative complication with individual ERAS element compliance.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The study enrolled 585 patients, and 475 completed the follow-up assessment. Patients with compliance over 80% had a significant reduction in postoperative complications (20.4% vs 41.2% vs 38.1%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001) and length of stay after surgery (4 vs 5 vs 4, <jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001). Increased compliance was also associated with higher patient satisfaction and QoR-15 scores (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001),. Among the five dimensions of the QoR-15, physical comfort (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05), physical independence (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05), and pain dimension (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.05) were better in the higher compliance groups. Minimally invasive surgery (MIS) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001), postoperative nausea and vomiting (PONV) prophylaxis (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001), early mobilization (<jats:italic>P<\/jats:italic>\u00a0=\u20090.031), early oral nutrition (<jats:italic>P<\/jats:italic>\u00a0=\u20090.012), and early removal of urinary drainage (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.001) were significantly associated with less complications. Having a postoperative complication was better predicted by the proposed nomogram model with high AUC value (0.906) and sensitivity (0.948) in the cohort.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Improved compliance with the ERAS protocol was associated with improved recovery and better patient experience undergoing hysterectomy. MIS, PONV prophylaxis, early mobilization, early oral intake, and early removal of urinary drainage were of concern in reducing postoperative complications.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Trial registration<\/jats:title>\n                <jats:p>Chinese Clinical Trial Registry, <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.chictr.org.cn\/edit.aspx?pid=31969&amp;htm=4\">ChiCTR1800019178<\/jats:ext-link>. Registered on 30\/10\/2018.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12871-021-01509-0","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T05:02:22Z","timestamp":1637557342000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Impact of enhanced recovery after surgery protocol compliance on patients\u2019 outcome in benign hysterectomy and establishment of a predictive nomogram model"],"prefix":"10.1186","volume":"21","author":[{"given":"Yiwei","family":"Shen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0063-5044","authenticated-orcid":false,"given":"Su","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gangming","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juying","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peipei","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"1509_CR1","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1016\/j.clnu.2005.02.002","volume":"24","author":"KC Fearon","year":"2005","unstructured":"Fearon KC, Ljungqvist O, Von Meyenfeldt M, Revhaug A, Dejong CH, Lassen K, et al. 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