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After continuous infusion of low-dose morphine, the pain was well-controlled with a decrease in the numeric rating scale (NRS) of pain score from 9 to 0, and the few adverse reactions to the treatment disappeared at a low dose of morphine.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The patient achieved a good quality of life during the one-month follow-up period.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12871-024-02426-8","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T06:02:11Z","timestamp":1708927331000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain"],"prefix":"10.1186","volume":"24","author":[{"given":"Qing","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-ling","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun-wu","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen-ping","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong-lin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu-zhou","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-ping","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6050-4792","authenticated-orcid":false,"given":"Cong","family":"Zou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"key":"2426_CR1","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1089\/jpm.2011.0326","volume":"15","author":"DC Currow","year":"2012","unstructured":"Currow DC, Spruyt O, Hardy J. Defining refractory pain in cancer for clinicians and researchers. J Palliat Med. 2012;15:5\u20136.","journal-title":"J Palliat Med"},{"key":"2426_CR2","first-page":"371","volume":"19","author":"JK Wang","year":"1978","unstructured":"Wang JK. Pain relief by intrathecal injection of serotonin or morphine. Ann Anesthesiol Fr. 1978;19:371\u20132.","journal-title":"Ann Anesthesiol Fr"},{"key":"2426_CR3","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1080\/17425247.2019.1642870","volume":"16","author":"S Jain","year":"2019","unstructured":"Jain S, Malinowski M, Chopra P, Varshney V, Deer TR. Intrathecal drug delivery for pain management: recent advances and future developments. 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J Clin Oncol. 2002;20:4040\u20139.","journal-title":"J Clin Oncol"},{"key":"2426_CR6","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/S0304-3959(96)03254-X","volume":"69","author":"S Grond","year":"1997","unstructured":"Grond S, Zech D, Lehmann KA, Radbruch L, Breitenbach H, Hertel D. Transdermal fentanyl in the long-term treatment of cancer pain: a prospective study of 50 patients with advanced cancer of the gastrointestinal tract or the head and neck region. Pain. 1997;69:191\u20138.","journal-title":"Pain"},{"key":"2426_CR7","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1159\/000509623","volume":"35","author":"D Dupoiron","year":"2020","unstructured":"Dupoiron D. Targeted drug delivery (Intrathecal and Intracranial) for treatment of Facial Pain. 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All methods were carried out in accordance with relevant guidelines and regulations. A written informed consent was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval and consent to participate"}},{"value":"A written informed consent for publication of the patient details of the case report was obtained from the patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"77"}}