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Ultrasound(US)-guided unilateral single-shot 0.25% ropivacaine L-ESPB was performed in the ESPB group, but not in the control group. Postoperative analgesic strategy for all patients: patient controlled intravenous analgesia (PCIA, diluted and dosed with fentanyl alone) was initiated immediately after surgery combined with oral compound codeine phosphate and ibuprofen sustained release tablets (1 tablet containing ibuprofen 200\u00a0mg and codeine 13\u00a0mg, 1 tablet\/q12h) commenced 6\u00a0h postoperatively. We collected and compared patient-centred correlates intraoperatively and 48\u00a0h postoperatively. The primary outcomes were intraoperative and postoperative opioid consumption and postoperative quality of recovery-15 (QoR-15) scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to the control group (<jats:italic>n<\/jats:italic>\u2009=\u200956), the ESPB group (<jats:italic>n<\/jats:italic>\u2009=\u200958) significantly reduced intraoperative remifentanil consumption (estimated median difference\u2009\u2212\u2009280 mcg, 95% confidence interval [CI]\u2009\u2212\u2009360 to\u2009\u2212\u2009200,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, power\u2009=\u2009100%); significantly reduced fentanyl consumption at 24\u00a0h postoperatively (estimated median difference\u2009\u2212\u200980mcg, 95%[CI]\u2009\u2212\u2009128 to\u2009\u2212\u200932,<jats:italic>p<\/jats:italic>\u2009=\u20090.001, power\u2009=\u200990%); and significantly enhanced the QoR-15 score at 24\u00a0h postoperatively (estimated median difference 11, 95%[CI] 8 to 14,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, power\u2009=\u2009100%). Compared to the control group, the ESPB group enhanced the resting numeric rating scale (NRS) score up to 8\u00a0h postoperatively, and the active movement NRS score up to 4\u00a0h postoperatively. The incidence of postoperative nausea and vomiting (PONV) (<jats:italic>p<\/jats:italic>\u2009=\u20090.015, power\u2009=\u200970%), abdominal distension (<jats:italic>p<\/jats:italic>\u2009=\u20090.024, power\u2009=\u200964%), and muscular calf vein thrombosis (MCVT) (<jats:italic>p<\/jats:italic>\u2009=\u20090.033, power\u2009=\u200958%) was lower in the ESPB group than in the control group. Moreover, the occurrence of L-ESPB related adverse reactions was not found herein.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>US-guided L-ESPB reduces intraoperative and 24\u00a0h postoperative opioid consumption and improves patients' QoR-15 scores at 24\u00a0h postoperatively. L-ESPB can be safely and effectively utilized in lumbar UBE surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial registration<\/jats:title><jats:p>Chinese Clinical Trial Registry,<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.chictr.org.cn\/showproj.html?proj=173379\">ChiCTR2200061908<\/jats:ext-link>, date of registration: 10\/07\/2022. Registry URL.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s12871-024-02601-x","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T05:24:53Z","timestamp":1719897893000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The efficacy of lumbar erector spinae plane block for postoperative analgesia management in patients undergoing lumbar unilateral bi-portal endoscopic surgery: a prospective randomized controlled trial"],"prefix":"10.1186","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1642-3764","authenticated-orcid":false,"given":"Dan","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0288-5925","authenticated-orcid":false,"given":"Hongkun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0727-5659","authenticated-orcid":false,"given":"Xin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5682-4542","authenticated-orcid":false,"given":"Zhenfeng","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0051-4453","authenticated-orcid":false,"given":"Chao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4947-6742","authenticated-orcid":false,"given":"Quanyi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,1]]},"reference":[{"issue":"1","key":"2601_CR1","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/s13018-018-0725-1","volume":"13","author":"SK Kim","year":"2018","unstructured":"Kim SK, Kang SS, Hong YH, Park SW, Lee SC. 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Written informed consents were obtained from all participants before inclusion. All methods in our study were performed in accordance with the relevant guidelines and regulations. Our study was registered in the Chinese Clinical Trial Registry on July 10, 2022, with the registration number ChiCTR2200061908.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"214"}}