{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T10:38:04Z","timestamp":1784025484018,"version":"3.55.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:00:00Z","timestamp":1758067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002839","name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002839","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Anesthesiol"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>The laryngeal mask airway (LMA) is essential in anesthesia, using an air-inflatable cuff for optimal pharyngeal fit. The i-gel<jats:sup>\u00ae<\/jats:sup> LMA (i-gel) is unique for its thermoplastic elastomer material making an air-inflatable cuff unnecessary and has shown higher oropharyngeal leak pressure (OLP) than first-generation LMA (cLMA) in neutral head position, however, mixed results for head rotation. This prospective study aimed to compare OLP between the cLMA and i-gel during head rotation.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>Patients undergoing elective surgery securing the airway with either cLMA or i-gel were included. Exclusion criteria included a Body Mass Index\u2009&gt;\u200930\u00a0kg\/m\u00b2, cervical spine pathologies or restricted head rotation. OLP was measured after induction at 60\u00b0 bilateral head rotation for primary outcome. Secondary outcomes were OLP at 0\u00b0 head rotation and postoperative complications on postoperative day 1.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>116 patients were randomized to either the cLMA (<jats:italic>n<\/jats:italic>\u2009=\u200960) or i-gel (<jats:italic>n<\/jats:italic>\u2009=\u200956) group. No significant difference was found in the OLP with 60\u00b0 head rotation to the left (cLMA 20 cmH<jats:sub>2<\/jats:sub>O [Interquartile range [IQR] 18\u201322], i-gel 21 cmH<jats:sub>2<\/jats:sub>O [IQR 18-22.75], <jats:italic>P<\/jats:italic>\u2009=\u20090.752) and the right (cLMA 20 cmH<jats:sub>2<\/jats:sub>O [IQR 18\u201322], i-gel 20 cmH<jats:sub>2<\/jats:sub>O [IQR 15\u201321], <jats:italic>P<\/jats:italic>\u2009=\u20090.324). OLP was also comparable in a neutral head position (<jats:italic>P<\/jats:italic>\u2009=\u20090.368). No significant differences in postoperative outcome were observed.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>This study demonstrated comparable OLP between cLMA and i-gel during head rotation. This indicates equivalent efficacy and seal integrity of both LMAs during head rotation, resulting in sufficient tidal volumes during rotated head positions.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Trial registration<\/jats:title>\n            <jats:p>German Clinical Trials Register, retrospectively registered under DRKS00031785 (date of registration 26.04.2023).<\/jats:p>\n          <\/jats:sec>","DOI":"10.1186\/s12871-025-03368-5","type":"journal-article","created":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T13:33:19Z","timestamp":1758115999000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of the oropharyngeal leak pressure in head rotation between a first-generation laryngeal mask and the i-gel laryngeal mask during general anesthesia - a randomized controlled trial"],"prefix":"10.1186","volume":"25","author":[{"given":"Philipp","family":"Brandhorst","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Palella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantin","family":"Cloeren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Voegeler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sascha","family":"Treskatsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0052-9604","authenticated-orcid":false,"given":"Moritz","family":"Weigeldt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,17]]},"reference":[{"issue":"8","key":"3368_CR1","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1093\/bja\/55.8.801","volume":"55","author":"Brain AI","year":"1983","unstructured":"Brain AI. 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Included patients gave their written informed consent. The study protocol was carried out in accordance with the Declaration of Helsinki and the CONSORT-Guidelines for randomized controlled trials.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"ST received funding for experimental research as well as honoraria for lectures from BMBF, BMWK, EFFRE, Edwards LifeSciences, BD, OrionPharma, AOP, Philips, Cytosorbents, & Chiesi outside this work. The other authors declare no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"448"}}