{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T09:46:57Z","timestamp":1777542417281,"version":"3.51.4"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T00:00:00Z","timestamp":1523836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T00:00:00Z","timestamp":1523836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["U01 NS041588"],"award-info":[{"award-number":["U01 NS041588"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000133","name":"Agency for Healthcare Research and Quality","doi-asserted-by":"publisher","award":["T32HS000066"],"award-info":[{"award-number":["T32HS000066"]}],"id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cardiovasc Disord"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1186\/s12872-018-0806-4","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:23:52Z","timestamp":1523881432000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["N-terminal pro-B-type natriuretic peptide and microsize myocardial infarction risk in the reasons for geographic and racial differences in stroke study"],"prefix":"10.1186","volume":"18","author":[{"given":"Madeline R.","family":"Sterling","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raegan W.","family":"Durant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanna","family":"Bryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily B.","family":"Levitan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todd M.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulia","family":"Khodneva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen P.","family":"Glasser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua S.","family":"Richman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Howard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Cushman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika M.","family":"Safford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,4,16]]},"reference":[{"issue":"5","key":"806_CR1","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1056\/NEJM199807303390507","volume":"339","author":"E Levin","year":"1998","unstructured":"Levin E, Gardner DG, Samson WK. Natriuretic peptides. N Engl J Med. 1998;339(5):321\u20138.","journal-title":"N Engl J Med"},{"issue":"14","key":"806_CR2","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1056\/NEJMoa011053","volume":"345","author":"JA de Lemos","year":"2001","unstructured":"de Lemos JA, Morrow DA, Bentley JH, et al. The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes. N Engl J Med. 2001;345(14):1014\u201321.","journal-title":"N Engl J Med"},{"issue":"2","key":"806_CR3","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1001\/jama.297.2.169","volume":"297","author":"K Bibbins-Domingo","year":"2007","unstructured":"Bibbins-Domingo K, Gupta R, Na B, Wu AH, Schiller NB, Whooley MA. N-terminal fragment of the prohormone brain-type natriuretic peptide (NT-proBNP), cardiovascular events, and mortality in patients with stable coronary heart disease. JAMA. 2007;297(2):169\u201376.","journal-title":"JAMA"},{"issue":"7","key":"806_CR4","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1056\/NEJMoa042330","volume":"352","author":"C Kragelund","year":"2005","unstructured":"Kragelund C, Gronning B, Kober L, Hildebrandt P, Steffensen R. N-terminal pro-B-type natriuretic peptide and long-term mortality in stable coronary heart disease. N Engl J Med. 2005;352(7):666\u201375.","journal-title":"N Engl J Med"},{"issue":"22","key":"806_CR5","doi-asserted-by":"publisher","first-page":"2177","DOI":"10.1161\/CIRCULATIONAHA.109.884866","volume":"120","author":"E Di Angelantonio","year":"2009","unstructured":"Di Angelantonio E, Chowdhury R, Sarwar N, et al. B-type natriuretic peptides and cardiovascular risk: systematic review and meta-analysis of 40 prospective studies. Circulation. 2009;120(22):2177\u201387.","journal-title":"Circulation"},{"issue":"20","key":"806_CR6","doi-asserted-by":"publisher","first-page":"3206","DOI":"10.1161\/01.CIR.0000147611.92021.2B","volume":"110","author":"C Heeschen","year":"2004","unstructured":"Heeschen C, Hamm CW, Mitrovic V, Lantelme NH, White HD. N-terminal pro-B-type natriuretic peptide levels for dynamic risk stratification of patients with acute coronary syndromes. Circulation. 2004;110(20):3206\u201312.","journal-title":"Circulation"},{"issue":"3","key":"806_CR7","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/S0735-1097(02)01986-1","volume":"40","author":"T Jernberg","year":"2002","unstructured":"Jernberg T, Stridsberg M, Venge P, Lindahl B. N-terminal pro brain natriuretic peptide on admission for early risk stratification of patients with chest pain and no ST-segment elevation. J Am Coll Cardiol. 2002;40(3):437\u201345.","journal-title":"J Am Coll Cardiol"},{"issue":"17","key":"806_CR8","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1001\/jama.2012.14306","volume":"308","author":"MM Safford","year":"2012","unstructured":"Safford MM, Brown TM, Muntner PM, et al. Association of race and sex with risk of incident acute coronary heart disease events. JAMA. 2012;308(17):1768\u201374.","journal-title":"JAMA"},{"issue":"29","key":"806_CR9","first-page":"1","volume":"17","author":"H Bhatt","year":"2015","unstructured":"Bhatt H, Safford M, Glasser S. Coronary heart disease risk factors and outcomes in the twenty-first century: findings from the REasons for geographic and racial differences in stroke (REGARDS) study. Curr Hypertens Rep. 2015;17(29):1\u201320.","journal-title":"Curr Hypertens Rep"},{"key":"806_CR10","first-page":"344","volume":"e1533","author":"NLLK Mills","year":"2012","unstructured":"Mills NLLK, McAllister DA, et al. Implications of lowering threshold of plasma troponin concentration in diagnosis of myocardial infarction: cohort study. The BMJ. 2012;344:e1533. The BMJ. 2012;e1533:344.","journal-title":"The BMJ"},{"key":"806_CR11","doi-asserted-by":"crossref","unstructured":"Morrow DA. Evidence-based decision limits for cardiac troponin: low-level elevation and prognosis. Am Heart J. Vol 148. United States2004:739\u2013742.","DOI":"10.1016\/j.ahj.2004.05.024"},{"issue":"12","key":"806_CR12","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1001\/jama.2011.338","volume":"305","author":"NL Mills","year":"2011","unstructured":"Mills NL, Churchhouse AM, Lee KK, et al. Implementation of a sensitive troponin I assay and risk of recurrent myocardial infarction and death in patients with suspected acute coronary syndrome. JAMA. 2011;305(12):1210\u20136.","journal-title":"JAMA"},{"issue":"19","key":"806_CR13","doi-asserted-by":"publisher","first-page":"2405","DOI":"10.1001\/jama.286.19.2405","volume":"286","author":"DA Morrow","year":"2001","unstructured":"Morrow DA, Cannon CP, Rifai N, et al. Ability of minor elevations of troponins I and T to predict benefit from an early invasive strategy in patients with unstable angina and non-ST elevation myocardial infarction: results from a randomized trial. JAMA. 2001;286(19):2405\u201312.","journal-title":"JAMA"},{"issue":"3","key":"806_CR14","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1159\/000086678","volume":"25","author":"VJ Howard","year":"2005","unstructured":"Howard VJ, Cushman M, Pulley L, et al. The reasons for geographic and racial differences in stroke study: objectives and design. Neuroepidemiology. 2005;25(3):135\u201343.","journal-title":"Neuroepidemiology"},{"issue":"9","key":"806_CR15","doi-asserted-by":"publisher","first-page":"1627","DOI":"10.1373\/clinchem.2008.122093","volume":"55","author":"M Cushman","year":"2009","unstructured":"Cushman M, McClure LA, Howard VJ, Jenny NS, Lakoski SG, Howard G. Implications of increased C-reactive protein for cardiovascular risk stratification in black and white men and women in the US. Clin Chem. 2009;55(9):1627\u201336.","journal-title":"Clin Chem"},{"key":"806_CR16","doi-asserted-by":"crossref","unstructured":"Cushman M, Callas PW, McClure LA, et al. N-terminal pro-B-type natriuretic peptide and risk of future cognitive impairment in the REGARDS cohort. Journal of Alzheimer's disease : JAD. 2016;","DOI":"10.3233\/JAD-160328"},{"key":"806_CR17","doi-asserted-by":"crossref","unstructured":"Zhang ZM, Prineas RJ, Eaton CB. Evaluation and comparison of the Minnesota Code and Novacode for electrocardiographic Q-ST wave abnormalities for the independent prediction of incident coronary heart disease and total mortality (from the Women's Health Initiative). The American journal of cardiology. 2010;106(1):18\u201325.e12.","DOI":"10.1016\/j.amjcard.2010.02.007"},{"issue":"20","key":"806_CR18","doi-asserted-by":"publisher","first-page":"2543","DOI":"10.1161\/01.CIR.0000100560.46946.EA","volume":"108","author":"RV Luepker","year":"2003","unstructured":"Luepker RV, Apple FS, Christenson RH, et al. Case definitions for acute coronary heart disease in epidemiology and clinical research studies: a statement from the AHA Council on epidemiology and prevention; AHA statistics committee; world heart federation council on epidemiology and prevention; the European Society of Cardiology Working Group on epidemiology and prevention; Centers for Disease Control and Prevention; and the National Heart, Lung, and Blood Institute. Circulation. 2003;108(20):2543\u20139.","journal-title":"Circulation"},{"key":"806_CR19","volume-title":"The Minnesota code manual of electrocardiographic findings: standards and procedures for measurement and classification","author":"RCR Prineas","year":"1982","unstructured":"Prineas RCR, Blackburn H. The Minnesota code manual of electrocardiographic findings: standards and procedures for measurement and classification. Boston, MA: Wright-OSG; 1982."},{"key":"806_CR20","unstructured":"Tate J BJ, Bunk D, et al. Analytical characteristics of commercial and research cardiac troponin I and T assays declared by the manufacturer. 2012; \n                    http:\/\/www.ifcc.org\/media\/102202\/IFCC_Troponin_Table_vDec_2010_FINAL_ug_L_28Jan11.pdf\n                    \n                  . Accessed September 24, 2017."},{"key":"806_CR21","unstructured":"Safford MM, Parmar G, Barasch CS, et al. Hospital laboratory reporting may be a barrier to detection of \u2018microsize\u2019 myocardial infarction in the US: an observational study. BMC Health Serv Res Vol 132013:162."},{"issue":"21","key":"806_CR22","doi-asserted-by":"publisher","first-page":"2269","DOI":"10.1093\/eurheartj\/ehi410","volume":"26","author":"GI Galasko","year":"2005","unstructured":"Galasko GI, Lahiri A, Barnes SC, Collinson P, Senior R. What is the normal range for N-terminal pro-brain natriuretic peptide? How well does this normal range screen for cardiovascular disease? Eur Heart J. 2005;26(21):2269\u201376.","journal-title":"Eur Heart J"},{"issue":"9","key":"806_CR23","doi-asserted-by":"publisher","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","volume":"150","author":"AS Levey","year":"2009","unstructured":"Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604\u201312.","journal-title":"Ann Intern Med"},{"issue":"3","key":"806_CR24","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1093\/biomet\/66.3.403","volume":"66","author":"RL Prentice","year":"1979","unstructured":"Prentice RL, Pyke R. Logistic disease incidence models and case-control studies. Biometrika. 1979;66(3):403\u201311.","journal-title":"Biometrika"},{"issue":"4","key":"806_CR25","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1016\/j.jclinepi.2006.06.022","volume":"60","author":"NC Onland-Moret","year":"2007","unstructured":"Onland-Moret NC, van der AD, van der Schouw YT, et al. Analysis of case-cohort data: a comparison of different methods. J Clin Epidemiol. 2007;60(4):350\u20135.","journal-title":"J Clin Epidemiol"},{"issue":"6","key":"806_CR26","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1161\/STROKEAHA.114.004712","volume":"45","author":"M Cushman","year":"2014","unstructured":"Cushman M, Judd SE, Howard VJ, et al. N-terminal pro-B-type natriuretic peptide and stroke risk: the reasons for geographic and racial differences in stroke cohort. Stroke. 2014;45(6):1646\u201350.","journal-title":"Stroke"},{"issue":"12","key":"806_CR27","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1016\/S0895-4356(99)00102-X","volume":"52","author":"WE Barlow","year":"1999","unstructured":"Barlow WE, Ichikawa L, Rosner D, Izumi S. Analysis of case-cohort designs. J Clin Epidemiol. 1999;52(12):1165\u201372.","journal-title":"J Clin Epidemiol"},{"issue":"2","key":"806_CR28","doi-asserted-by":"publisher","first-page":"524","DOI":"10.2307\/2532940","volume":"51","author":"M Lunn","year":"1995","unstructured":"Lunn M, McNeil D. Applying cox regression to competing risks. Biometrics. 1995;51(2):524\u201332.","journal-title":"Biometrics"},{"key":"806_CR29","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1002\/sim.4780100410","volume":"10","author":"DBSN Rubin","year":"1991","unstructured":"Rubin DBSN. Multiple imputation in health-care databases: an overview and some applications. Stat Med. 1991;10:585\u201398.","journal-title":"Stat Med"},{"issue":"22","key":"806_CR30","doi-asserted-by":"publisher","first-page":"2634","DOI":"10.1161\/CIRCULATIONAHA.107.187397","volume":"116","author":"K Thygesen","year":"2007","unstructured":"Thygesen K, Alpert JS, White HD, et al. Universal definition of myocardial infarction. Circulation. 2007;116(22):2634\u201353.","journal-title":"Circulation"},{"issue":"20","key":"806_CR31","doi-asserted-by":"publisher","first-page":"2551","DOI":"10.1093\/eurheartj\/ehs184","volume":"33","author":"K Thygesen","year":"2012","unstructured":"Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. Eur Heart J. 2012;33(20):2551\u201367.","journal-title":"Eur Heart J"},{"issue":"9","key":"806_CR32","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1093\/eurheartj\/eht530","volume":"35","author":"C Mueller","year":"2014","unstructured":"Mueller C. Biomarkers and acute coronary syndromes: an update. Eur Heart J. 2014;35(9):552\u20136.","journal-title":"Eur Heart J"},{"key":"806_CR33","doi-asserted-by":"crossref","unstructured":"Konstam MA. Natriuretic peptides and cardiovascular events: more than a stretch. Jama. Vol 297. United States2007:212\u2013214.","DOI":"10.1001\/jama.297.2.212"},{"key":"806_CR34","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e1533","volume":"344","author":"NL Mills","year":"2012","unstructured":"Mills NL, Lee KK, McAllister DA, et al. Implications of lowering threshold of plasma troponin concentration in diagnosis of myocardial infarction: cohort study. BMJ (Clinical research ed). 2012;344:e1533.","journal-title":"BMJ (Clinical research ed)"},{"issue":"19","key":"806_CR35","doi-asserted-by":"publisher","first-page":"2118","DOI":"10.1016\/j.jacc.2010.01.044","volume":"55","author":"M Bonaca","year":"2010","unstructured":"Bonaca M, Scirica B, Sabatine M, et al. Prospective evaluation of the prognostic implications of improved assay performance with a sensitive assay for cardiac troponin I. J Am Coll Cardiol. 2010;55(19):2118\u201324.","journal-title":"J Am Coll Cardiol"},{"issue":"4","key":"806_CR36","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1177\/2047487315569675","volume":"23","author":"LE Pastormerlo","year":"2016","unstructured":"Pastormerlo LE, Maffei S, Della Latta D, Chubuchny V, Susini C, Berti S, Clerico A, Prontera C, Passino C, Januzzi JL, Emdin M. N-terminal prob-type natriuretic peptide is a marker of vascular remodelling and subclinical atherosclerosis in asymptomatic hypertensives. Eur J Prev Cardiol. 2016;23(4):366\u201376.","journal-title":"Eur J Prev Cardiol"},{"issue":"23","key":"806_CR37","doi-asserted-by":"publisher","first-page":"2872","DOI":"10.1161\/01.CIR.0000129305.25115.80","volume":"109","author":"WE Hopkins","year":"2004","unstructured":"Hopkins WE, Chen Z, Fukagawa NK, Hall C, Knot HJ, LeWinter MM. Increased atrial and brain natriuretic peptides in adults with cyanotic congenital heart disease: enhanced understanding of the relationship between hypoxia and natriuretic peptide secretion. Circulation. 2004;109(23):2872\u20137.","journal-title":"Circulation"},{"key":"806_CR38","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1002\/clc.4960231016","volume":"23","author":"JMM Tateishi","year":"2000","unstructured":"Tateishi JMM, Ohyanagi M, Iwasaki T. Transient increase in plasma brain (B-type) natriuretic peptide after percutaneous transluminal coronary angioplasty. Clin Cardiol. 2000;23:776\u201380.","journal-title":"Clin Cardiol"},{"key":"806_CR39","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1096\/fj.03-1336fje","volume":"18","author":"JPGA Goetze","year":"2004","unstructured":"Goetze JPGA, Moller CH, Steinbruchel DA, Rehfeld JF, Nielsen LB. Acute myocardial hypoxia increases BNP gene expression. FASEB J. 2004;18:1928\u201330.","journal-title":"FASEB J"},{"key":"806_CR40","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1161\/01.RES.0000130526.20854.fa","volume":"94","author":"NLP Min","year":"2004","unstructured":"Min NLP, Khaper N, Liu P. Inflammatory cytokines and Postmyocardial Infarcation remodeling. Circ Res. 2004;94:1543\u201353.","journal-title":"Circ Res"},{"issue":"12","key":"806_CR41","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1161\/01.RES.0000046234.73401.70","volume":"91","author":"T Tsuruda","year":"2002","unstructured":"Tsuruda T, Boerrigter G, Huntley BK, et al. Brain natriuretic peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002;91(12):1127\u201334.","journal-title":"Circ Res"},{"key":"806_CR42","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1042\/CS20110168","volume":"123","author":"MKF Pauriah","year":"2012","unstructured":"Pauriah MKF, Lim TK, et al. B-type natriuretic peptide is an independent predictor of endothelial function in man. Clin Sci. 2012;123:307\u201312.","journal-title":"Clin Sci"},{"key":"806_CR43","unstructured":"Luchner A, Hengstenberg C, Lowel H, Riegger GA, Schunkert H, Holmer S. Effect of compensated renal dysfunction on approved heart failure markers: direct comparison of brain natriuretic peptide (BNP) and N-terminal pro-BNP. Hypertension (Dallas, Tex. : 1979). 2005;46(1):118\u201323."},{"issue":"7","key":"806_CR44","doi-asserted-by":"publisher","first-page":"1803","DOI":"10.1161\/STROKEAHA.113.001128","volume":"44","author":"RT Dadu","year":"2013","unstructured":"Dadu RT, Fornage M, Virani SS, et al. Cardiovascular biomarkers and subclinical brain disease in the atherosclerosis risk in communities study. Stroke. 2013;44(7):1803\u20138.","journal-title":"Stroke"},{"issue":"8","key":"806_CR45","doi-asserted-by":"publisher","first-page":"1698","DOI":"10.1161\/ATVBAHA.116.307545","volume":"36","author":"U Mutlu","year":"2016","unstructured":"Mutlu U, Ikram MA, Hofman A, de Jong PT, Klaver CC, Ikram MK. N-terminal pro-B-type natriuretic peptide is related to retinal microvascular damage: the Rotterdam study. Arterioscler Thromb Vasc Biol. 2016;36(8):1698\u2013702.","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"10","key":"806_CR46","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1093\/ajh\/hpv026","volume":"28","author":"JK Bower","year":"2015","unstructured":"Bower JK, Lazo M, Matsushita K, et al. N-terminal pro-brain natriuretic peptide (NT-proBNP) and risk of hypertension in the atherosclerosis risk in communities (ARIC) study. Am J Hypertens. 2015;28(10):1262\u20136.","journal-title":"Am J Hypertens"},{"issue":"10","key":"806_CR47","first-page":"840","volume":"4","author":"C Natriuretic Peptides Studies","year":"2016","unstructured":"Natriuretic Peptides Studies C, Willeit P, Kaptoge S, et al. Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis. The lancet. Diabetes & endocrinology. 2016;4(10):840\u20139.","journal-title":"Diabetes & endocrinology"},{"issue":"9","key":"806_CR48","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1016\/j.amjcard.2005.06.073","volume":"96","author":"SM Abdullah","year":"2005","unstructured":"Abdullah SM, Khera A, Das SR, et al. Relation of coronary atherosclerosis determined by electron beam computed tomography and plasma levels of n-terminal pro-brain natriuretic peptide in a multiethnic population-based sample (the Dallas heart study). Am J Cardiol. 2005;96(9):1284\u20139.","journal-title":"Am J Cardiol"},{"issue":"2","key":"806_CR49","doi-asserted-by":"publisher","first-page":"667","DOI":"10.3892\/etm.2016.3371","volume":"12","author":"L Gan","year":"2016","unstructured":"Gan L, Feng C, Liu C, Tian S, Song X, Yang L. Association between serum N-terminal pro-B-type natriuretic peptide levels and characteristics of coronary atherosclerotic plaque detected by coronary computed tomography angiography. Experimental and therapeutic medicine. 2016;12(2):667\u201375.","journal-title":"Experimental and therapeutic medicine"},{"issue":"5","key":"806_CR50","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/j.amjcard.2004.10.034","volume":"95","author":"G Ndrepepa","year":"2005","unstructured":"Ndrepepa G, Braun S, Mehilli J, et al. Plasma levels of N-terminal pro-brain natriuretic peptide in patients with coronary artery disease and relation to clinical presentation, angiographic severity, and left ventricular ejection fraction. Am J Cardiol. 2005;95(5):553\u20137.","journal-title":"Am J Cardiol"}],"container-title":["BMC Cardiovascular Disorders"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-018-0806-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12872-018-0806-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-018-0806-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T13:06:56Z","timestamp":1589461616000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccardiovascdisord.biomedcentral.com\/articles\/10.1186\/s12872-018-0806-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,16]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["806"],"URL":"https:\/\/doi.org\/10.1186\/s12872-018-0806-4","relation":{},"ISSN":["1471-2261"],"issn-type":[{"value":"1471-2261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,16]]},"assertion":[{"value":"8 May 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 April 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study protocol was reviewed and approved by the University of Alabama at Birmingham Institutional Review Board and all participants provided written informed consent.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Dr. Durant receives support from Amgen related to the treatment of heart failure. He also receives research grant funding from Amarin related to primary and secondary prevention of myocardial infarction. Dr. Levitan receives research grants from Amgen related to treatment of heart failure and other cardiovascular disease (significant) and does consulting for Amgen and Novartis related to treatment of heart failure (modest). Dr. Brown receives Amgen support for research related to heart failure. Dr. Safford receives salary support for investigator-initiated research from Amgen, Inc. All other authors have no conflicts or competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Publisher\u2019s Note"}}],"article-number":"66"}}