{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T14:49:46Z","timestamp":1768834186666,"version":"3.49.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T00:00:00Z","timestamp":1588636800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T00:00:00Z","timestamp":1588636800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006520","name":"Edwards Lifesciences","doi-asserted-by":"publisher","award":["410007511"],"award-info":[{"award-number":["410007511"]}],"id":[{"id":"10.13039\/100006520","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cardiovasc Disord"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Background<\/jats:title>\n<jats:p>Aortic stenosis (AS) is a common cardiac condition whose prevalence increases with age. The symptom burden associated with severe aortic stenosis (AS) can introduce significant lifestyle disruptions and if left untreated can lead to a poor prognosis. Quality of life (QoL) is an important consideration in these patients. The TASQ is a QoL tool that was developed for aortic stenosis patients. We evaluated the psychometric properties of this specific questionnaire in patients who underwent transcatheter aortic valve implantation (TAVI), which is a therapeutic option for patients with severe aortic stenosis (AS).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The properties of the TASQ in measuring QoL were evaluated in AS patients undergoing TAVI. Patients presenting for the TAVI procedure (<jats:italic>N<\/jats:italic>\u2009=\u200962) were evaluated pre-TAVI, at discharge, 1-month, and 3-month follow-ups. Demographic information as well as caregiver status, and daily activities were recorded. In addition to the TASQ, they completed the KCCQ (Kansas City Cardiomyopathy Questionnaire) and the IIRS (Illness Intrusiveness Rating Scale).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The TASQ is a 16-item self-administered questionnaire that assesses AS-specific QoL across five domains: physical symptoms; physical limitations; emotional impact; social limitations, and health expectations. TASQ subscales are internally consistent (\u03b1\u2009=\u20090.74\u20130.96) and showed significant improvements from baseline across assessments (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Construct validity evidence was demonstrated by correlations consistent with theoretically derived hypotheses across time points.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The TASQ is a brief measure of AS-specific QoL that is sensitive to change in patients undergoing TAVI. Items on the TASQ capture important QoL concerns reported by AS patients, suggesting this is a measure of relevant and meaningful outcomes for this patient population. Detection of early improvements in QoL by the TASQ is promising, with important implications for the evaluation of procedural outcomes in this population.<\/jats:p>\n<\/jats:sec>","DOI":"10.1186\/s12872-020-01477-2","type":"journal-article","created":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T19:03:07Z","timestamp":1588705387000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Toronto aortic stenosis quality of life questionnaire (TASQ): validation in TAVI patients"],"prefix":"10.1186","volume":"20","author":[{"given":"Rima","family":"Styra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Dimas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathy","family":"Svitak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamta","family":"Kapoor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Osten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maral","family":"Ouzounian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Devins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Deckert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Horlick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,5,5]]},"reference":[{"key":"1477_CR1","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s12471-012-0364-9","volume":"21","author":"MWA Van Geldorp","year":"2013","unstructured":"Van Geldorp MWA, Heuvelman HJ, Kappetein AP, Busschbach JJV, Cohen DJ, Takkenbergt JJM, et al. Quality of life among patients with severe aortic stenosis. Neth Hear J. 2013;21:21\u20137.","journal-title":"Neth Hear J"},{"key":"1477_CR2","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1097\/JCN.0b013e3181b99828","volume":"25","author":"LB Nugteren","year":"2010","unstructured":"Nugteren LB, Sandau KE. Critical review of health-related quality of life studies of patients with aortic stenosis. J Cardiovasc Nurs. 2010;25:25\u201339.","journal-title":"J Cardiovasc Nurs"},{"key":"1477_CR3","doi-asserted-by":"crossref","unstructured":"Liu Z, Kidney E, Bem D, Bramley G, Bayliss S, de Belder MA, et al. Transcatheter aortic valve implantation for aortic stenosis in high surgical risk patients: A systematic review and meta-analysis. PloS ONE. 2018;13(5).","DOI":"10.1371\/journal.pone.0196877"},{"key":"1477_CR4","doi-asserted-by":"publisher","first-page":"488","DOI":"10.1016\/j.mayocp.2018.01.020","volume":"93","author":"A Kanwar","year":"2018","unstructured":"Kanwar A, Thaden JJ, Nkomo VT. Management of patients with aortic valve stenosis. Mayo Clin Proceedings. 2018;93:488\u2013508.","journal-title":"Mayo Clin Proceedings"},{"key":"1477_CR5","doi-asserted-by":"publisher","first-page":"1964","DOI":"10.1161\/CIRCULATIONAHA.111.040022","volume":"124","author":"M Reynolds","year":"2011","unstructured":"Reynolds M, Magnuson EA, Lei Y, Leon MB, Smith CR, Sveensson LG, et al. Health-related quality of life after aortic valve replacement in inoperable patients with severe aortic stenosis. Circulation. 2011;124:1964\u201372.","journal-title":"Circulation"},{"key":"1477_CR6","doi-asserted-by":"publisher","first-page":"1597","DOI":"10.1056\/NEJMoa1008232","volume":"363","author":"MB Leon","year":"2010","unstructured":"Leon MB, Smith CR, Mack M, Miller C, Moses JW, Svensson LG, et al. Transcatheter aortic valve implantation for aortic stenosis in patients who cannot undergo surgery. New Engl J Med. 2010;363:1597\u2013607.","journal-title":"New Engl J Med"},{"key":"1477_CR7","first-page":"216","volume":"1","author":"T Walther","year":"2012","unstructured":"Walther T. Kempfert J Transapical vs. transfemoral aortic valve implantation: which approach for which patient, from a surgeon's standpoint. Ann Cardiothorac Surg. 2012;1:216\u20139.","journal-title":"Ann Cardiothorac Surg"},{"key":"1477_CR8","first-page":"156","volume":"354","author":"PO Vandvik","year":"2016","unstructured":"Vandvik PO, Otto CM, Siemieniuk RA, Bagur R, Guyatt GH, Lytvyn L, et al. Choice of intervention for those with severe aortic stenosis. BMJ. 2016;354:156\u20138.","journal-title":"BMJ"},{"key":"1477_CR9","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1093\/ejcts\/ezw406","volume":"51","author":"N Bonaros","year":"2017","unstructured":"Bonaros N, Petzina R, Cocchieri R, Jagielak D, Aiello M, Lapeze J, et al. Transaortic transcatheter aortic valve implantation as a first-line choice or as a last resort? An analysis based on the ROUTE registry. Eur J Cardiothorac Surg. 2017;51:919\u201326.","journal-title":"Eur J Cardiothorac Surg"},{"key":"1477_CR10","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1161\/CIRCOUTCOMES.113.000354","volume":"6","author":"SV Arnold","year":"2013","unstructured":"Arnold SV, Spertus JA, Lei Y, Green P, Kirtane AJ, Kapadia S, et al. How to define a poor outcome after transcatheter aortic valve replacement: conceptual framework and empirical observations from the placement of aortic transcatheter valve (PARTNER) trial. Circ Cardiovasc Qual Outcomes. 2013;6:591\u20137.","journal-title":"Circ Cardiovasc Qual Outcomes"},{"key":"1477_CR11","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.cjca.2017.11.007","volume":"34","author":"AW Asgar","year":"2018","unstructured":"Asgar AW, Lauck S, Ko D, Lambert LJ, Kass M, Adams C, et al. (On behalf of the CCS quality indicators TAVI working group). The Transcatheter aortic valve implantation (TAVI) quality report: a call to arms for improving quality in Canada. Can J Cardiol. 2018;34:330\u20132.","journal-title":"Can J Cardiol"},{"key":"1477_CR12","doi-asserted-by":"publisher","first-page":"2635","DOI":"10.1093\/eurheartj\/ehy107","volume":"39","author":"AP Durko","year":"2018","unstructured":"Durko AP, Rl O. Van Mieghem NM, Milojevic M, Mylotte D, Nkomo VT, et al. annual number of candidates for transcatheter aortic valve implantation per country: current estimates and future projections. Eur Heart J. 2018;39:2635\u201342.","journal-title":"Eur Heart J"},{"key":"1477_CR13","doi-asserted-by":"publisher","first-page":"2001","DOI":"10.1093\/eurheartj\/ehu205","volume":"35","author":"SD Anker","year":"2014","unstructured":"Anker SD, Agewall S, Borggrefe M, Calvert M, Jaime Caro J, Cowie MR, et al. The importance of patient-reported outcomes: a call for their comprehensive integration in cardiovascular clinical trials. Eur Heart J. 2014;35:2001\u20139.","journal-title":"Eur Heart J"},{"key":"1477_CR14","doi-asserted-by":"publisher","first-page":"1357","DOI":"10.1136\/bmj.322.7298.1357","volume":"322","author":"AJ Carr","year":"2001","unstructured":"Carr AJ, Higginson IJ. Are quality of life measures patient centered? BMJ. 2001;322:1357\u201360.","journal-title":"BMJ"},{"key":"1477_CR15","doi-asserted-by":"publisher","first-page":"1244","DOI":"10.4065\/82.10.1244","volume":"82","author":"EA Hahn","year":"2007","unstructured":"Hahn EA, Cella D, Chassany O, Fairclough DL, Wong GY, Hays RD, et al. Precision of health-related quality-of-life data compared with other clinical measures. Mayo Clin Proc. 2007;82:1244\u201354.","journal-title":"Mayo Clin Proc"},{"key":"1477_CR16","doi-asserted-by":"crossref","unstructured":"EuroQoL Group EuroQol-a new facility for the measurement of health-related quality of life. Health Policy. 1990;16:199\u2013208.","DOI":"10.1016\/0168-8510(90)90421-9"},{"key":"1477_CR17","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1097\/00005650-199303000-00006","volume":"31","author":"CA McHorney","year":"1993","unstructured":"McHorney CA, Ware JE Jr, Raczek AE. The MOS 36-item short-form health survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care. 1993;31:247\u201363.","journal-title":"Med Care"},{"key":"1477_CR18","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1097\/00005650-199603000-00003","volume":"34","author":"JE Ware Jr","year":"1996","unstructured":"Ware JE Jr, Kosinski M, Keller SD. A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34:220\u201333.","journal-title":"Med Care"},{"key":"1477_CR19","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1016\/S0735-1097(00)00531-3","volume":"35","author":"CP Green","year":"2000","unstructured":"Green CP, Porter CB, Bresnahan DR, Spertus JA. Development and evaluation of the Kansas City cardiomyopathy questionnaire: a new health status measure for heart failure. J Am Coll Cardiol. 2000;35:1245\u201355.","journal-title":"J Am Coll Cardiol"},{"key":"1477_CR20","first-page":"198","volume":"3","author":"TS Rector","year":"1987","unstructured":"Rector TS, Kubo SH, Cohn JN. Patient's self-assessment of their congestive heart failure. Part 2: content, reliability, and validity of a new measure: the Minnesota living with heart failure questionnaire. Heart Failure. 1987;3:198\u2013219.","journal-title":"Heart Failure"},{"key":"1477_CR21","doi-asserted-by":"publisher","unstructured":"Frank D, Kennon S, Bonaros N, Romano M, Lefevere T, Di Mario C, et al. A trial protocol for the validation of the \u201cToronto Aortic Stenosis Quality of Life (TASQ) Questionnaire\u201d in patients undergoing Surgical Aortic Valve Replacement (SAVR) or Transfemoral (TF) Transcatheter Aortic Valve Implantation (TAVI) - The TASQ Registry. Open Heart. 2019;21;6(1): e001008. doi: https:\/\/doi.org\/10.1136\/openhrt-2019-001008.","DOI":"10.1136\/openhrt-2019-001008"},{"key":"1477_CR22","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1001\/jamacardio.2016.5302","volume":"2","author":"SV Arnold","year":"2017","unstructured":"Arnold SV, Spertus JA, Vemulapalli S, Li Z, Matsouaka RA, Baron SJ, et al. Quality-of-life outcomes after transcatheter aortic valve replacement in an unselected population: a report from the STS\/ACC Transcatheter valve therapy registry. JAMA Cardiol. 2017;2:409\u201316.","journal-title":"JAMA Cardiol"},{"key":"1477_CR23","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1161\/CIRCHEARTFAILURE.112.970053","volume":"6","author":"SV Arnold","year":"2013","unstructured":"Arnold SV, Spertus JA, Lei Y, Allen KB, Chhatriwalla AK, Leon MB, et al. Use of the Kansas City cardiomyopathy questionnaire for monitoring health status in patients with aortic stenosis. Circ Heart Fail. 2013;6:61\u20137.","journal-title":"Circ Heart Fail"},{"key":"1477_CR24","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1016\/j.cjca.2012.04.015","volume":"28","author":"J Webb","year":"2012","unstructured":"Webb J, Rodes-Cabau J, Fremes S, Pibarot P, Ruel M, Ibrahim R, et al. Transcatheter aortic valve implantation: a Canadian cardiovascular society position statement. Can J Cardiol. 2012;28:520\u20138.","journal-title":"Can J Cardiol"},{"key":"1477_CR25","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1016\/j.jpsychores.2009.05.006","volume":"68","author":"GM Devins","year":"2010","unstructured":"Devins GM. Using the illness intrusiveness ratings scale to understand health-related quality of life in chronic disease. J Psychosom Res. 2010;68:591\u2013602.","journal-title":"J Psychosom Res"},{"key":"1477_CR26","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1017\/CBO9780511996214","volume-title":"Measurement in medicine","author":"HCW De Vet","year":"2011","unstructured":"De Vet HCW, Terwee CB, Mokkink LB, Knol DL. Measurement in medicine. Cambridge: Cambridge University Press; 2011. p. 126\u201386."},{"key":"1477_CR27","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1111\/opn.12026","volume":"9","author":"J Horrocks","year":"2014","unstructured":"Horrocks J, Closs J, Astin F. Quality of life in older adults with aortic stenosis: a narrative review. Int J Older People Nursing. 2014;9:227\u201346.","journal-title":"Int J Older People Nursing"},{"key":"1477_CR28","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1370\/afm.1239","volume":"9","author":"RM Epstein","year":"2011","unstructured":"Epstein RM, Street RL. The values and value of patient-centered care. Ann Fam Med. 2011;9:100\u20133.","journal-title":"Ann Fam Med"},{"key":"1477_CR29","doi-asserted-by":"crossref","unstructured":"Dauerman HL, Reardon MJ, Popma JJ, Little SH, Cavalcante JL, Adams DH, et al. Early recovery of left ventricular systolic function after corevalve transcatheter aortic valve replacement. Circ Cardiovasc Interv. 2016;9(6).","DOI":"10.1161\/CIRCINTERVENTIONS.115.003425"},{"issue":"7","key":"1477_CR30","doi-asserted-by":"publisher","first-page":"612","DOI":"10.5603\/KP.a2014.0065","volume":"72","author":"P Kleczynski","year":"2014","unstructured":"Kleczynski P, Bagienski M, Sorysz D, Rzeszutko L, Trebacz J, Tomala M, et al. Short- and intermediate-term improvement of patient quality of life after transcatheter aortic valve implantation: a single study. Kardiol Pol. 2014;72(7):612\u20136.","journal-title":"Kardiol Pol"},{"key":"1477_CR31","unstructured":"Kleczynski P, Dziewierz A, Bagienski M, Rzeszutko L, Sorysz, D Trebacz J et al. Long-Term Mortality and Quality of Life After Transcatheter Aortic Valve Insertion in Very Elderly Patients J Invasive Cardiol 2016;28(): 492\u2013496."},{"issue":"8","key":"1477_CR32","doi-asserted-by":"publisher","first-page":"444","DOI":"10.5301\/ijao.5000521","volume":"39","author":"P Kleczynski","year":"2016","unstructured":"Kleczynski P, Bagienski M, Dziewierz A, Rzeszutko L, Sorysz D, Trebacz J, et al. Twelve-month quality of life improvement and all-cause mortality in elderly patients undergoing transcatheter aortic valve replacement. Int J Artif Organs. 2016;39(8):444\u20139.","journal-title":"Int J Artif Organs"},{"key":"1477_CR33","first-page":"174","volume":"165","author":"MV Mondloch","year":"2001","unstructured":"Mondloch MV, Cole DC, Frank JW. Does how you do depend on how you think you\u2019ll do? A systematic review of the evidence for a relation between patients\u2019 recovery expectations and health outcomes. CMAJ. 2001;165:174\u20139.","journal-title":"CMAJ"},{"key":"1477_CR34","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s12529-015-9500-4","volume":"23","author":"CJ Auer","year":"2016","unstructured":"Auer CJ, Glombiewski JA, Doering BK, Winkler A, Laferton JA, Broadbent E, et al. Patients' expectations predict surgery outcomes: a meta-analysis. Int J Behav Med. 2016;23:49\u201362.","journal-title":"Int J Behav Med"}],"container-title":["BMC Cardiovascular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-020-01477-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12872-020-01477-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-020-01477-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,4]],"date-time":"2021-05-04T23:08:09Z","timestamp":1620169689000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccardiovascdisord.biomedcentral.com\/articles\/10.1186\/s12872-020-01477-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,5]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["1477"],"URL":"https:\/\/doi.org\/10.1186\/s12872-020-01477-2","relation":{},"ISSN":["1471-2261"],"issn-type":[{"value":"1471-2261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,5]]},"assertion":[{"value":"20 November 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 April 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 May 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"University Health Network Research Ethics Board for the Toronto General Hospital Research Institute (16\u20135745) approved the process of patient recruitment and patients provided informed written consent to participate.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Participants were informed that only anonymized group data would be published. Individual patient data are not reported.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"R. Styra has the copyright for the Toronto Aortic Stenosis Quality of Life Questionnaire. The other authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"209"}}