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The purpose of this study was to investigate the risk factors for isolated CAE complicated with CSF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 126 patients with isolated CAE were selected retrospectively. The patients were grouped into the no CSF (NCSF) group (n\u2009=\u200955) and the CSF group (n\u2009=\u200971) according to the corrected thrombolysis in myocardial infarction (TIMI) frame count (CTFC). Data on demographics, laboratory measurements, left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDd), CTFC and diameters of three coronary arteries were collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The proportions of males (84.5% vs. 61.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004) and patients with a smoking history (63.4% vs. 43.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.021) were higher in the CSF group than in the NCSF group. The neutrophil-to-lymphocyte ratio (NLR) (2.08(1.68\u20133.21) vs. 1.89\u2009\u00b1\u20090.58,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001), mean diameter of coronary arteries (mean D) (5.50\u2009\u00b1\u20090.85 vs. 5.18\u2009\u00b1\u20090.91,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and uric acid (URIC) level (370.78\u2009\u00b1\u2009109.79 vs. 329.15\u2009\u00b1\u200979.71,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.019) were significantly higher in the CSF group, while the lymphocyte-to-monocyte ratio (LMR) (4.81\u2009\u00b1\u20091.66 vs. 5.96\u2009\u00b1\u20091.75,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and albumin (ALB) level (44.13\u2009\u00b1\u20094.10 vs. 45.69\u2009\u00b1\u20094.11,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036) were lower. Multivariable logistic analysis showed that the LMR (odds ratio: 0.614, 95% CI: 0.464\u20130.814,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001), mean D (odds ratio: 2.643, 95% CI: 1.54\u20134.51, p\u2009&lt;\u20090.001) and URIC level (odds ratio: 1.006, 95% CI: 1.001\u20131.012,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018) were independent predictors of CSF in CAE.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The LMR was a negative independent predictor of CSF in isolated CAE, while URIC level and mean D were positive independent predictors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1186\/s12872-021-01952-4","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T21:02:33Z","timestamp":1617051753000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Association of the lymphocyte-to-monocyte ratio, mean diameter of coronary arteries, and uric acid level with coronary slow flow in isolated coronary artery ectasia"],"prefix":"10.1186","volume":"21","author":[{"given":"Zhuoxuan","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiansong","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JinGang","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Guan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2956-7233","authenticated-orcid":false,"given":"Shubin","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,3,30]]},"reference":[{"issue":"2","key":"1952_CR1","doi-asserted-by":"publisher","first-page":"123","DOI":"10.5543\/tkda.2013.17003","volume":"41","author":"T Isik","year":"2013","unstructured":"Isik T, Ayhan E, Uyarel H, Tanboga IH, Kurt M, Uluganyan M, Ergelen M, Eksik A. 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