{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T01:18:46Z","timestamp":1794359926900,"version":"4.9.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T00:00:00Z","timestamp":1637280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T00:00:00Z","timestamp":1637280000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cardiovasc Disord"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>When compared with older reports of untreated symptomatic aortic valve stenosis (AoS), urgent transcatheter aortic valve implantation (u-TAVI) seems to improve mortality rates. We performed a single centre, retrospective cohort analysis to characterize our u-TAVI population and to identify potential predictors of worse outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We performed a retrospective analysis of\u00a0631 consecutive TAVI patients between 2013 and 2018. Of these patients, 53 were categorized as u-TAVI. Data was collected from the local electronic database.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Urgent patients had more often a severely decreased left ventricular ejection fraction (LVEF\u2009&lt;\u200930%) and increased creatinine levels (115.5 [88\u2013147] vs 94.5 [78\u2013116] mmol\/l; <jats:italic>p<\/jats:italic>\u2009=\u20090.001). Urgent patients were hospitalised for 18 [10\u201328] days before and discharged 6 [4\u20139] days after the implantation. The incidence of peri-procedural complications and apical implantations was comparable among the study groups. Urgent patients had higher in-hospital (11.3% vs 3.1%; <jats:italic>p<\/jats:italic>\u2009=\u20090.011) and 1-year mortality rates (28.2% vs 8.5%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). An increased risk of one-year mortality was associated with urgency (HR 3.5; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), apical access (HR 1.9; <jats:italic>p<\/jats:italic>\u2009=\u20090.016) and cerebrovascular complications (HR 4.3; <jats:italic>p<\/jats:italic>\u2009=\u20090.002). Within the urgent group, the length of pre-hospital admission was the only significant predictor of 1-year mortality (HR 1.037\/day; <jats:italic>p<\/jats:italic>\u2009=\u20090.003).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Compared to elective procedures, u-TAVI led to increased mortality and comparable complication rates. This detrimental effect is most likely related to the length of pre-procedural hospitalisation of urgent patients.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12872-021-02347-1","type":"journal-article","created":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T11:02:49Z","timestamp":1637319769000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Urgent transcatheter aortic valve implantation in an all-comer population: a single-centre experience"],"prefix":"10.1186","volume":"21","author":[{"given":"Arpad","family":"Lux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo F.","family":"Veenstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Kats","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wim","family":"Dohmen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos G.","family":"Maessen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnoud W. 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The retrospective analysis their data and the publication of the results was approved by the ethical committee at Maastricht University and Maastricht UMC\u2009+\u2009(METC azM\/UM). Approval number: METC- 2019-15239. All methods were carried out in accordance with relevant guidelines and regulations in the declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Our manuscript does not contain any individual person\u2019s data in any form. The local ethical committee (METC azM\/UM) approved the publication of this retrospective analysis of medical records.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors, however, have no financial conflict of interests to declare.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"550"}}