{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:57:50Z","timestamp":1787101070889,"version":"build-2736575974"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cardiovasc Disord"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>A noninvasive left ventricular (LV) pressure-strain loop (PSL) provides a new method to quantify myocardial work (MW) by combining global longitudinal strain (GLS) and LV pressure, which exerts potential advantages over traditional GLS. We studied the LV PSL and MW in patients with type 2 diabetes mellitus (T2DM).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This cross-sectional study included 201 subjects (54 healthy controls and 147 T2DM patients) who underwent complete two-dimensional echocardiography (2DE), including 2D speckle-tracking echocardiography (STE), as well as brachial artery pulse pressure measurement. The PSL was used to determine the global myocardial work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE) of all study participants. The association between T2DM and LV function was evaluated according to these MW indices.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The GLS was significantly lower in the T2DM group than in the control group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), indicating that the LV myocardium had been damaged, although the LV ejection fraction (LVEF) was still normal. The GWI and GWE were decreased (<jats:italic>P<\/jats:italic>\u2009=\u20090.022) and the GWW was increased (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) in diabetic patients compared with controls, but the GCW was comparable in the two groups (<jats:italic>P<\/jats:italic>\u2009=\u20090.160). In all diabetic patients, age, body mass index, systolic blood pressure, smoking history, and LVEF were correlated with GWI, GWW and GWE.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The use of LV PSL is a novel noninvasive technique that could help to depict the relationship between LV myocardial damage and MW in patients with T2DM.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12872-022-02482-3","type":"journal-article","created":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:03:38Z","timestamp":1645056218000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Echocardiographic study of myocardial work in patients with type 2 diabetes mellitus"],"prefix":"10.1186","volume":"22","author":[{"given":"Lisi","family":"Liao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bobo","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhimin","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fajin","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulin","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5380-4625","authenticated-orcid":false,"given":"Jinfeng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,2,17]]},"reference":[{"key":"2482_CR1","doi-asserted-by":"crossref","first-page":"107843","DOI":"10.1016\/j.diabres.2019.107843","volume":"157","author":"P Saeedi","year":"2019","unstructured":"Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, Colagiuri S, Guariguata L, Motala AA, Ogurtsova K, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9(th) edition. Diabetes Res Clin Pract. 2019;157:107843.","journal-title":"Diabetes Res Clin Pract"},{"issue":"2","key":"2482_CR2","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.diabres.2013.11.002","volume":"103","author":"L Guariguata","year":"2014","unstructured":"Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract. 2014;103(2):137\u201349.","journal-title":"Diabetes Res Clin Pract"},{"issue":"3","key":"2482_CR3","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.jacc.2017.11.019","volume":"71","author":"TH Marwick","year":"2018","unstructured":"Marwick TH, Ritchie R, Shaw JE, Kaye D. Implications of underlying mechanisms for the recognition and management of diabetic cardiomyopathy. J Am Coll Cardiol. 2018;71(3):339\u201351.","journal-title":"J Am Coll Cardiol"},{"issue":"2","key":"2482_CR4","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.jchf.2014.08.004","volume":"3","author":"A Dei Cas","year":"2015","unstructured":"Dei Cas A, Khan SS, Butler J, Mentz RJ, Bonow RO, Avogaro A, Tschoepe D, Doehner W, Greene SJ, Senni M, et al. Impact of diabetes on epidemiology, treatment, and outcomes of patients with heart failure. JACC Heart Fail. 2015;3(2):136\u201345.","journal-title":"JACC Heart Fail"},{"issue":"12","key":"2482_CR5","doi-asserted-by":"publisher","first-page":"2554","DOI":"10.2337\/db17-1434","volume":"67","author":"D Torella","year":"2018","unstructured":"Torella D, Iaconetti C, Tarallo R, Marino F, Giurato G, Veneziano C, Aquila I, Scalise M, Mancuso T, Cianflone E, et al. miRNA regulation of the hyperproliferative phenotype of vascular smooth muscle cells in diabetes. Diabetes. 2018;67(12):2554\u201368.","journal-title":"Diabetes"},{"issue":"7","key":"2482_CR6","doi-asserted-by":"publisher","first-page":"e294","DOI":"10.1161\/CIR.0000000000000691","volume":"140","author":"SM Dunlay","year":"2019","unstructured":"Dunlay SM, Givertz MM, Aguilar D, Allen LA, Chan M, Desai AS, Deswal A, Dickson VV, Kosiborod MN, Lekavich CL, et al. Type 2 diabetes mellitus and heart failure: a scientific statement from the American Heart Association and the Heart Failure Society of America: this statement does not represent an update of the 2017 ACC\/AHA\/HFSA heart failure guideline update. Circulation. 2019;140(7):e294\u2013324.","journal-title":"Circulation"},{"issue":"6","key":"2482_CR7","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1016\/S0735-1097(01)01183-4","volume":"37","author":"F Ledru","year":"2001","unstructured":"Ledru F, Ducimeti\u00e8re P, Battaglia S, Courbon D, Beverelli F, Guize L, Guermonprez JL, Di\u00e9bold B. New diagnostic criteria for diabetes and coronary artery disease: insights from an angiographic study. J Am Coll Cardiol. 2001;37(6):1543\u201350.","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"2482_CR8","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1161\/CIRCRESAHA.118.311371","volume":"124","author":"HC Kenny","year":"2019","unstructured":"Kenny HC, Abel ED. Heart failure in type 2 diabetes mellitus. Circ Res. 2019;124(1):121\u201341.","journal-title":"Circ Res"},{"issue":"3","key":"2482_CR9","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1210\/jc.2011-2037","volume":"97","author":"R Marfella","year":"2012","unstructured":"Marfella R, Sasso FC, Cacciapuoti F, Portoghese M, Rizzo MR, Siniscalchi M, Carbonara O, Ferraraccio F, Torella M, Petrella A, et al. Tight glycemic control may increase regenerative potential of myocardium during acute infarction. J Clin Endocrinol Metab. 2012;97(3):933\u201342.","journal-title":"J Clin Endocrinol Metab"},{"key":"2482_CR10","doi-asserted-by":"publisher","first-page":"3106056","DOI":"10.1155\/2018\/3106056","volume":"2018","author":"FC Sasso","year":"2018","unstructured":"Sasso FC, Rinaldi L, Lascar N, Marrone A, Pafundi PC, Adinolfi LE, Marfella R. Role of tight glycemic control during acute coronary syndrome on CV outcome in type 2 diabetes. J Diabetes Res. 2018;2018:3106056.","journal-title":"J Diabetes Res"},{"issue":"1","key":"2482_CR11","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1042\/CS20030153","volume":"106","author":"ZY Fang","year":"2004","unstructured":"Fang ZY, Leano R, Marwick TH. Relationship between longitudinal and radial contractility in subclinical diabetic heart disease. Clin Sci (Lond). 2004;106(1):53\u201360.","journal-title":"Clin Sci (Lond)"},{"issue":"5","key":"2482_CR12","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.echo.2014.01.001","volume":"27","author":"L Ernande","year":"2014","unstructured":"Ernande L, Bergerot C, Girerd N, Thibault H, Davidsen ES, Gautier Pignon-Blanc P, Amaz C, Croisille P, De Buyzere ML, Rietzschel ER, et al. Longitudinal myocardial strain alteration is associated with left ventricular remodeling in asymptomatic patients with type 2 diabetes mellitus. J Am Soc Echocardiogr. 2014;27(5):479\u201388.","journal-title":"J Am Soc Echocardiogr"},{"issue":"10","key":"2482_CR13","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1016\/j.echo.2020.05.010","volume":"33","author":"YL Hiemstra","year":"2020","unstructured":"Hiemstra YL, van der Bijl P, El Mahdiui M, Bax JJ, Delgado V, Marsan NA. Myocardial work in nonobstructive hypertrophic cardiomyopathy: implications for outcome. J Am Soc Echocardiogr. 2020;33(10):1201\u20138.","journal-title":"J Am Soc Echocardiogr"},{"issue":"6","key":"2482_CR14","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1093\/eurheartj\/ehs016","volume":"33","author":"K Russell","year":"2012","unstructured":"Russell K, Eriksen M, Aaberge L, Wilhelmsen N, Skulstad H, Remme EW, Haugaa KH, Opdahl A, Fjeld JG, Gjesdal O, et al. A novel clinical method for quantification of regional left ventricular pressure-strain loop area: a non-invasive index of myocardial work. Eur Heart J. 2012;33(6):724\u201333.","journal-title":"Eur Heart J"},{"issue":"1","key":"2482_CR15","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1093\/ehjci\/jey156","volume":"20","author":"E Boe","year":"2019","unstructured":"Boe E, Skulstad H, Smiseth OA. Myocardial work by echocardiography: a novel method ready for clinical testing. Eur Heart J Cardiovasc Imaging. 2019;20(1):18\u201320.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"9","key":"2482_CR16","doi-asserted-by":"publisher","first-page":"1120","DOI":"10.1016\/j.echo.2019.05.002","volume":"32","author":"M El Mahdiui","year":"2019","unstructured":"El Mahdiui M, van der Bijl P, Abou R, Ajmone Marsan N, Delgado V, Bax JJ. Global left ventricular myocardial work efficiency in healthy individuals and patients with cardiovascular disease. J Am Soc Echocardiogr. 2019;32(9):1120\u20137.","journal-title":"J Am Soc Echocardiogr"},{"issue":"3","key":"2482_CR17","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.echo.2020.10.014","volume":"34","author":"F Fortuni","year":"2021","unstructured":"Fortuni F, Butcher SC, van der Kley F, Lustosa RP, Karalis I, de Weger A, Priori SG, van der Bijl P, Bax JJ, Delgado V, et al. Left ventricular myocardial work in patients with severe aortic stenosis. J Am Soc Echocardiogr. 2021;34(3):257\u201366.","journal-title":"J Am Soc Echocardiogr"},{"key":"2482_CR18","doi-asserted-by":"crossref","unstructured":"Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of, Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2016;17(4):412.","DOI":"10.1093\/ehjci\/jew041"},{"issue":"5","key":"2482_CR19","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1093\/ehjci\/jey188","volume":"20","author":"R Manganaro","year":"2019","unstructured":"Manganaro R, Marchetta S, Dulgheru R, Ilardi F, Sugimoto T, Robinet S, Cimino S, Go YY, Bernard A, Kacharava G, et al. Echocardiographic reference ranges for normal non-invasive myocardial work indices: results from the EACVI NORRE study. Eur Heart J Cardiovasc Imaging. 2019;20(5):582\u201390.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"3","key":"2482_CR20","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1093\/ehjci\/jeaa301","volume":"22","author":"OA Smiseth","year":"2021","unstructured":"Smiseth OA, Donal E, Penicka M, Sletten OJ. How to measure left ventricular myocardial work by pressure-strain loops. Eur Heart J Cardiovasc Imaging. 2021;22(3):259\u201361.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"1","key":"2482_CR21","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s12933-018-0703-2","volume":"17","author":"WD Strain","year":"2018","unstructured":"Strain WD, Pald\u00e1nius PM. Diabetes, cardiovascular disease and the microcirculation. Cardiovasc Diabetol. 2018;17(1):57.","journal-title":"Cardiovasc Diabetol"},{"issue":"7","key":"2482_CR22","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1038\/s41581-020-0278-5","volume":"16","author":"JB Cole","year":"2020","unstructured":"Cole JB, Florez JC. Genetics of diabetes mellitus and diabetes complications. Nat Rev Nephrol. 2020;16(7):377\u201390.","journal-title":"Nat Rev Nephrol"},{"issue":"11","key":"2482_CR23","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1016\/j.echo.2017.06.010","volume":"30","author":"J Chan","year":"2017","unstructured":"Chan J, Shiino K, Obonyo NG, Hanna J, Chamberlain R, Small A, Scalia IG, Scalia W, Yamada A, Hamilton-Craig CR, et al. Left ventricular global strain analysis by two-dimensional speckle-tracking echocardiography: the learning curve. J Am Soc Echocardiogr. 2017;30(11):1081\u201390.","journal-title":"J Am Soc Echocardiogr"},{"issue":"1","key":"2482_CR24","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1186\/s12968-016-0269-7","volume":"18","author":"G Pedrizzetti","year":"2016","unstructured":"Pedrizzetti G, Claus P, Kilner PJ, Nagel E. Principles of cardiovascular magnetic resonance feature tracking and echocardiographic speckle tracking for informed clinical use. J Cardiovasc Magn Reson. 2016;18(1):51.","journal-title":"J Cardiovasc Magn Reson"},{"issue":"4","key":"2482_CR25","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1007\/s00125-014-3171-6","volume":"57","author":"H Bugger","year":"2014","unstructured":"Bugger H, Abel ED. Molecular mechanisms of diabetic cardiomyopathy. Diabetologia. 2014;57(4):660\u201371.","journal-title":"Diabetologia"},{"issue":"1","key":"2482_CR26","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1093\/ehjci\/jey131","volume":"20","author":"J Chan","year":"2019","unstructured":"Chan J, Edwards NFA, Khandheria BK, Shiino K, Sabapathy S, Anderson B, Chamberlain R, Scalia GM. A new approach to assess myocardial work by non-invasive left ventricular pressure-strain relations in hypertension and dilated cardiomyopathy. Eur Heart J Cardiovasc Imaging. 2019;20(1):31\u20139.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"12","key":"2482_CR27","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1093\/ehjci\/jey024","volume":"19","author":"A Hubert","year":"2018","unstructured":"Hubert A, Le Rolle V, Leclercq C, Galli E, Samset E, Casset C, Mabo P, Hernandez A, Donal E. Estimation of myocardial work from pressure-strain loops analysis: an experimental evaluation. Eur Heart J Cardiovasc Imaging. 2018;19(12):1372\u20139.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"7","key":"2482_CR28","doi-asserted-by":"publisher","first-page":"H996","DOI":"10.1152\/ajpheart.00191.2013","volume":"305","author":"K Russell","year":"2013","unstructured":"Russell K, Eriksen M, Aaberge L, Wilhelmsen N, Skulstad H, Gjesdal O, Edvardsen T, Smiseth OA. Assessment of wasted myocardial work: a novel method to quantify energy loss due to uncoordinated left ventricular contractions. Am J Physiol Heart Circ Physiol. 2013;305(7):H996-1003.","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"5","key":"2482_CR29","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1093\/ehjci\/jez203","volume":"21","author":"R Manganaro","year":"2020","unstructured":"Manganaro R, Marchetta S, Dulgheru R, Sugimoto T, Tsugu T, Ilardi F, Cicenia M, Ancion A, Postolache A, Martinez C, et al. Correlation between non-invasive myocardial work indices and main parameters of systolic and diastolic function: results from the EACVI NORRE study. Eur Heart J Cardiovasc Imaging. 2020;21(5):533\u201341.","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"25","key":"2482_CR30","doi-asserted-by":"publisher","first-page":"3213","DOI":"10.1161\/CIRCULATIONAHA.106.679597","volume":"115","author":"S Boudina","year":"2007","unstructured":"Boudina S, Abel ED. Diabetic cardiomyopathy revisited. Circulation. 2007;115(25):3213\u201323.","journal-title":"Circulation"},{"issue":"22","key":"2482_CR31","doi-asserted-by":"publisher","first-page":"1793","DOI":"10.1016\/j.jacc.2008.07.062","volume":"52","author":"LJ Rijzewijk","year":"2008","unstructured":"Rijzewijk LJ, van der Meer RW, Smit JW, Diamant M, Bax JJ, Hammer S, Romijn JA, de Roos A, Lamb HJ. Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus. J Am Coll Cardiol. 2008;52(22):1793\u20139.","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"2482_CR32","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1161\/01.RES.49.6.1268","volume":"49","author":"TJ Regan","year":"1981","unstructured":"Regan TJ, Wu CF, Yeh CK, Oldewurtel HA, Haider B. Myocardial composition and function in diabetes. The effects of chronic insulin use. Circ Res. 1981;49(6):1268\u201377.","journal-title":"Circ Res"},{"issue":"8","key":"2482_CR33","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1161\/CIRCRESAHA.118.314665","volume":"124","author":"WH Dillmann","year":"2019","unstructured":"Dillmann WH. Diabetic cardiomyopathy. Circ Res. 2019;124(8):1160\u20132.","journal-title":"Circ Res"},{"issue":"10","key":"2482_CR34","doi-asserted-by":"publisher","first-page":"3077","DOI":"10.2337\/diabetes.51.10.3077","volume":"51","author":"A Hansen","year":"2002","unstructured":"Hansen A, Johansson BL, Wahren J, von Bibra H. C-peptide exerts beneficial effects on myocardial blood flow and function in patients with type 1 diabetes. Diabetes. 2002;51(10):3077\u201382.","journal-title":"Diabetes"},{"issue":"1","key":"2482_CR35","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/s12872-020-01372-w","volume":"20","author":"ANR Batista","year":"2020","unstructured":"Batista ANR, Garcia T, Franco EAT, Azevedo PS, Barbosa MF, Zornoff LAM, Minicucci MF, de Paiva SAR, Zucchi JW, de Godoy I, et al. Comparison of morphometry and ventricular function of healthy and smoking young people. BMC Cardiovasc Disord. 2020;20(1):66.","journal-title":"BMC Cardiovasc Disord"},{"issue":"1","key":"2482_CR36","doi-asserted-by":"publisher","first-page":"6608","DOI":"10.1038\/s41598-020-63509-3","volume":"10","author":"T Hendriks","year":"2020","unstructured":"Hendriks T, van Dijk R, Alsabaan NA, van der Harst P. Active tobacco smoking impairs cardiac systolic function. Sci Rep. 2020;10(1):6608.","journal-title":"Sci Rep"},{"issue":"25","key":"2482_CR37","doi-asserted-by":"publisher","first-page":"2148","DOI":"10.1016\/j.jacc.2008.09.014","volume":"52","author":"DA Bluemke","year":"2008","unstructured":"Bluemke DA, Kronmal RA, Lima JA, Liu K, Olson J, Burke GL, Folsom AR. The relationship of left ventricular mass and geometry to incident cardiovascular events: the MESA (Multi-Ethnic Study of Atherosclerosis) study. J Am Coll Cardiol. 2008;52(25):2148\u201355.","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"2482_CR38","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1186\/s12933-021-01262-1","volume":"20","author":"WF Yan","year":"2021","unstructured":"Yan WF, Gao Y, Zhang Y, Guo YK, Wang J, Jiang L, Li Y, Yang ZG. Impact of type 2 diabetes mellitus on left ventricular diastolic function in patients with essential hypertension: evaluation by volume-time curve of cardiac magnetic resonance. Cardiovasc Diabetol. 2021;20(1):73.","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"2482_CR39","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1186\/s12933-020-01138-w","volume":"19","author":"XM Li","year":"2020","unstructured":"Li XM, Jiang L, Guo YK, Ren Y, Han PL, Peng LQ, Shi R, Yan WF, Yang ZG. The additive effects of type 2 diabetes mellitus on left ventricular deformation and myocardial perfusion in essential hypertension: a 3.0 T cardiac magnetic resonance study. Cardiovasc Diabetol. 2020;19(1):161.","journal-title":"Cardiovasc Diabetol"},{"issue":"7","key":"2482_CR40","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1007\/s10554-020-01833-5","volume":"36","author":"X Chen","year":"2020","unstructured":"Chen X, Guo H, Yang Q, Fang J, Kang X. Quantitative evaluation of subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus by three-dimensional echocardiography. Int J Cardiovasc Imaging. 2020;36(7):1311\u20139.","journal-title":"Int J Cardiovasc Imaging"},{"issue":"6","key":"2482_CR41","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.2337\/dc20-0129","volume":"43","author":"GS Gulsin","year":"2020","unstructured":"Gulsin GS, Swarbrick DJ, Athithan L, Brady EM, Henson J, Baldry E, Argyridou S, Jaicim NB, Squire G, Walters Y, et al. Effects of low-energy diet or exercise on cardiovascular function in working-age adults with type 2 diabetes: a prospective, randomized, open-label, blinded end point trial. Diabetes Care. 2020;43(6):1300\u201310.","journal-title":"Diabetes Care"},{"issue":"9","key":"2482_CR42","doi-asserted-by":"publisher","first-page":"e015716","DOI":"10.1161\/JAHA.119.015716","volume":"9","author":"I Ikonomidis","year":"2020","unstructured":"Ikonomidis I, Pavlidis G, Thymis J, Birba D, Kalogeris A, Kousathana F, Kountouri A, Balampanis K, Parissis J, Andreadou I, et al. Effects of glucagon-like peptide-1 receptor agonists, sodium-glucose cotransporter-2 inhibitors, and their combination on endothelial glycocalyx, arterial function, and myocardial work index in patients with type 2 diabetes mellitus after 12-month treatment. J Am Heart Assoc. 2020;9(9):e015716.","journal-title":"J Am Heart Assoc"}],"container-title":["BMC Cardiovascular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-022-02482-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12872-022-02482-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-022-02482-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:04:11Z","timestamp":1645056251000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccardiovascdisord.biomedcentral.com\/articles\/10.1186\/s12872-022-02482-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,17]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["2482"],"URL":"https:\/\/doi.org\/10.1186\/s12872-022-02482-3","relation":{},"ISSN":["1471-2261"],"issn-type":[{"value":"1471-2261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,17]]},"assertion":[{"value":"30 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 January 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 February 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was in accordance with the Declaration of Heksinki and was approved by the medical ethics committee of Shenzhen People's Hospital.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"59"}}