{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:51:54Z","timestamp":1782125514184,"version":"3.54.5"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cardiovasc Disord"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Despite surgical advances, acute type A aortic dissection remains a life-threatening disease with high mortality and morbidity. Tracheostomy is usually used for patients who need prolonged mechanical ventilation in the intensive care unit (ICU). However, data on the risk factors for requiring tracheostomy and the impact of tracheostomy on outcomes in patients after Stanford\u00a0type A acute\u00a0aortic dissection surgery (AADS) are limited.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A retrospective single-institutional study including consecutive patients who underwent AADS between January 2016 and December 2019 was conducted. Patients who died intraoperatively were excluded. Univariate analysis and multivariate logistic\u00a0regression analysis were used to identify independent risk factors for postoperative tracheostomy (POT). A nomogram to predict the probability of POT was constructed based on independent predictors and their beta-coefficients. The area under the receiver operating characteristic curve (AUC) was performed to assess the discrimination of the model. Calibration plots and the Hosmer\u2013Lemeshow test were used to evaluate calibration. Clinical usefulness of the nomogram was assessed by decision curve analysis. Propensity score matching analysis was used to analyze the correlation between requiring tracheostomy and clinical prognosis.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>There were 492 patients included in this study for analysis, including 55 patients (11.2%) requiring tracheostomy after AADS. Compared with patients without POT, patients with POT experienced longer ICU and hospital stay and higher mortality. Age, cerebrovascular disease history, preoperative white blood cell (WBC) count and renal insufficiency, intraoperative amount of red blood cell (RBC) transfusion and platelet transfusion were identified as independent risk factors for POT. Our constructed nomogram had good discrimination with an AUC\u2009=\u20090.793 (0.729\u20130.856). Good calibration and clinical utility were observed through the calibration and decision curves, respectively. For better clinical application, we defined four intervals that stratified patients from very low to high risk for occurrence of POT.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Our study identified preoperative and intraoperative risk factors for POT and found that requiring tracheostomy was related to the poor outcomes in patients undergoing AADS. The established prediction model was validated with well predictive performance and clinical utility, and it may be useful for individual risk assessment and early clinical decision-making to reduce the incidence of tracheostomy.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12872-022-02538-4","type":"journal-article","created":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T16:20:45Z","timestamp":1646842845000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Predictors and outcomes of postoperative tracheostomy in patients undergoing acute type A aortic dissection surgery"],"prefix":"10.1186","volume":"22","author":[{"given":"Dashuai","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongfei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anchen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinling","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,9]]},"reference":[{"issue":"3","key":"2538_CR1","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1016\/s0022-5223(03)00583-x","volume":"126","author":"LS De Santo","year":"2003","unstructured":"De Santo LS, Romano G, Amarelli C, Onorati F, Torella M, Renzulli A, et al. Surgical repair of acute type A aortic dissection: continuous pulmonary perfusion during retrograde cerebral perfusion prevents lung injury in a pilot study. J Thorac Cardiovasc Surg. 2003;126(3):826\u201331. https:\/\/doi.org\/10.1016\/s0022-5223(03)00583-x.","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"5","key":"2538_CR2","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1053\/j.jvca.2017.03.036","volume":"31","author":"M Jin","year":"2017","unstructured":"Jin M, Ma WG, Liu S, Zhu J, Sun L, Lu J, et al. Predictors of prolonged mechanical ventilation in adults after acute Type-A aortic dissection repair. J Cardiothorac Vasc Anesth. 2017;31(5):1580\u20137. https:\/\/doi.org\/10.1053\/j.jvca.2017.03.036.","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"11","key":"2538_CR3","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.1253\/circj.cj-08-0306","volume":"72","author":"N Kimura","year":"2008","unstructured":"Kimura N, Tanaka M, Kawahito K, Sanui M, Yamaguchi A, Ino T, et al. Risk factors for prolonged mechanical ventilation following surgery for acute type a aortic dissection. Circ J. 2008;72(11):1751\u20137. https:\/\/doi.org\/10.1253\/circj.cj-08-0306.","journal-title":"Circ J"},{"issue":"1","key":"2538_CR4","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1053\/j.jvca.2018.07.014","volume":"33","author":"E Litton","year":"2019","unstructured":"Litton E, Law T, Stamp N. Tracheostomy in patients requiring prolonged mechanical ventilation after cardiac surgery. J Cardiothorac Vasc Anesth. 2019;33(1):91\u20132. https:\/\/doi.org\/10.1053\/j.jvca.2018.07.014.","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"6","key":"2538_CR5","doi-asserted-by":"publisher","first-page":"2135","DOI":"10.1016\/j.athoracsur.2013.06.085","volume":"96","author":"GM Comas","year":"2013","unstructured":"Comas GM, Leshnower BG, Halkos ME, Thourani VH, Puskas JD, Guyton RA, et al. Acute type a dissection: impact of antegrade cerebral perfusion under moderate hypothermia. Ann Thorac Surg. 2013;96(6):2135\u201341. https:\/\/doi.org\/10.1016\/j.athoracsur.2013.06.085.","journal-title":"Ann Thorac Surg"},{"key":"2538_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2020.12.113","author":"C Lau","year":"2021","unstructured":"Lau C, Robinson NB, Farrington WJ, Rahouma M, Gambardella I, Gaudino M, et al. A tailored strategy for repair of acute type A aortic dissection. J Thorac Cardiovasc Surg. 2021. https:\/\/doi.org\/10.1016\/j.jtcvs.2020.12.113.","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"9","key":"2538_CR7","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1097\/00003246-199909000-00003","volume":"27","author":"MH Kollef","year":"1999","unstructured":"Kollef MH, Ahrens TS, Shannon W. Clinical predictors and outcomes for patients requiring tracheostomy in the intensive care unit. Crit Care Med. 1999;27(9):1714\u201320. https:\/\/doi.org\/10.1097\/00003246-199909000-00003.","journal-title":"Crit Care Med"},{"key":"2538_CR8","doi-asserted-by":"publisher","DOI":"10.12659\/aot.920630","volume":"25","author":"RC Graham","year":"2020","unstructured":"Graham RC, Bush WJ, Mella JS, Fridell JA, Ekser B, Mihaylov P, et al. Tracheostomy post liver transplant: predictors, complications, and outcomes. Ann Transplant. 2020;25: e920630. https:\/\/doi.org\/10.12659\/aot.920630.","journal-title":"Ann Transplant"},{"issue":"6","key":"2538_CR9","doi-asserted-by":"publisher","first-page":"2285","DOI":"10.1016\/j.athoracsur.2016.01.046","volume":"101","author":"CW Mastropietro","year":"2016","unstructured":"Mastropietro CW, Benneyworth BD, Turrentine M, Wallace AS, Hornik CP, Jacobs JP, et al. Tracheostomy after operations for congenital heart disease: an analysis of the society of thoracic surgeons congenital heart surgery database. Ann Thorac Surg. 2016;101(6):2285\u201392. https:\/\/doi.org\/10.1016\/j.athoracsur.2016.01.046.","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"2538_CR10","doi-asserted-by":"publisher","first-page":"533","DOI":"10.21037\/jtd-20-2578","volume":"13","author":"Z Hu","year":"2021","unstructured":"Hu Z, Wang Z, Chang J, Zhang M, Hu X, Ren Z, et al. Application of prosthesis eversion method for ascending aorta replacement guarantees better clinical outcomes of type A acute aortic dissection surgery. J Thorac Dis. 2021;13(2):533\u201340. https:\/\/doi.org\/10.21037\/jtd-20-2578.","journal-title":"J Thorac Dis"},{"issue":"4","key":"2538_CR11","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1016\/j.jtcvs.2005.09.038","volume":"131","author":"PA Walts","year":"2006","unstructured":"Walts PA, Murthy SC, Arroliga AC, Yared JP, Rajeswaran J, Rice TW, et al. Tracheostomy after cardiovascular surgery: an assessment of long-term outcome. J Thorac Cardiovasc Surg. 2006;131(4):830\u20137. https:\/\/doi.org\/10.1016\/j.jtcvs.2005.09.038.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2538_CR12","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.642912","volume":"12","author":"SS Mukerji","year":"2021","unstructured":"Mukerji SS, Das S, Alabsi H, Brenner LN, Jain A, Magdamo C, et al. Prolonged intubation in patients with prior cerebrovascular disease and COVID-19. Front Neurol. 2021;12: 642912. https:\/\/doi.org\/10.3389\/fneur.2021.642912.","journal-title":"Front Neurol"},{"issue":"1","key":"2538_CR13","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s12028-017-0390-y","volume":"27","author":"H Schneider","year":"2017","unstructured":"Schneider H, Hertel F, Kuhn M, Ragaller M, Gottschlich B, Trabitzsch A, et al. Decannulation and functional outcome after tracheostomy in patients with severe stroke (DECAST): a prospective observational study. Neurocrit Care. 2017;27(1):26\u201334. https:\/\/doi.org\/10.1007\/s12028-017-0390-y.","journal-title":"Neurocrit Care"},{"issue":"2","key":"2538_CR14","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1177\/0194599816675323","volume":"156","author":"SK Gadkaree","year":"2017","unstructured":"Gadkaree SK, Pandian V, Best S, Motz KM, Allen C, Kim Y, et al. Laryngotracheal stenosis: risk factors for tracheostomy dependence and dilation interval. Otolaryngol Head Neck Surg. 2017;156(2):321\u20138. https:\/\/doi.org\/10.1177\/0194599816675323.","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"3","key":"2538_CR15","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1016\/j.athoracsur.2019.02.063","volume":"108","author":"T Songdechakraiwut","year":"2019","unstructured":"Songdechakraiwut T, Aftab M, Chatterjee S, Green SY, Price MD, Preventza O, et al. Tracheostomy after thoracoabdominal aortic aneurysm repair: risk factors and outcomes. Ann Thorac Surg. 2019;108(3):778\u201384. https:\/\/doi.org\/10.1016\/j.athoracsur.2019.02.063.","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"2538_CR16","doi-asserted-by":"publisher","first-page":"S870","DOI":"10.1016\/j.athoracsur.2006.10.099","volume":"83","author":"CD Etz","year":"2007","unstructured":"Etz CD, Di Luozzo G, Bello R, Luehr M, Khan MZ, Bodian CA, et al. Pulmonary complications after descending thoracic and thoracoabdominal aortic aneurysm repair: predictors, prevention, and treatment. Ann Thorac Surg. 2007;83(2):S870-6. https:\/\/doi.org\/10.1016\/j.athoracsur.2006.10.099.","journal-title":"Ann Thorac Surg."},{"issue":"3","key":"2538_CR17","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1159\/000195516","volume":"54","author":"H Bark","year":"1988","unstructured":"Bark H, Heimer D, Chaimovitz C, Mostoslovski M. Effect of chronic renal failure on respiratory muscle strength. Respiration. 1988;54(3):153\u201361. https:\/\/doi.org\/10.1159\/000195516.","journal-title":"Respiration"},{"issue":"3","key":"2538_CR18","doi-asserted-by":"publisher","first-page":"230949901986180","DOI":"10.1177\/2309499019861809","volume":"27","author":"Z Mu","year":"2019","unstructured":"Mu Z, Zhang Z. Risk factors for tracheostomy after traumatic cervical spinal cord injury. J Orthop Surg (Hong Kong). 2019;27(3):2309499019861809. https:\/\/doi.org\/10.1177\/2309499019861809.","journal-title":"J Orthop Surg (Hong Kong)"},{"issue":"13\u201314","key":"2538_CR19","doi-asserted-by":"publisher","first-page":"1642","DOI":"10.1080\/02699052.2016.1199915","volume":"30","author":"SS Humble","year":"2016","unstructured":"Humble SS, Wilson LD, McKenna JW, Leath TC, Song Y, Davidson MA, et al. Tracheostomy risk factors and outcomes after severe traumatic brain injury. Brain Inj. 2016;30(13\u201314):1642\u20137. https:\/\/doi.org\/10.1080\/02699052.2016.1199915.","journal-title":"Brain Inj"},{"issue":"2","key":"2538_CR20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0228954","volume":"15","author":"K Suzuki","year":"2020","unstructured":"Suzuki K, Kimura N, Mieno M, Hori D, Sezai A, Yamaguchi A, et al. Factors related to white blood cell elevation in acute type A aortic dissection. PLoS ONE. 2020;15(2): e0228954. https:\/\/doi.org\/10.1371\/journal.pone.0228954.","journal-title":"PLoS ONE"},{"issue":"2","key":"2538_CR21","doi-asserted-by":"publisher","first-page":"735","DOI":"10.21037\/jtd-20-2736","volume":"13","author":"M Ge","year":"2021","unstructured":"Ge M, Wang Z, Chen T, Cheng Y, Ye J, Lu L, et al. Risk factors for and outcomes of prolonged mechanical ventilation in patients received DeBakey type I aortic dissection repairment. J Thorac Dis. 2021;13(2):735\u201342. https:\/\/doi.org\/10.21037\/jtd-20-2736.","journal-title":"J Thorac Dis"},{"issue":"5","key":"2538_CR22","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1536\/ihj.15-484","volume":"57","author":"R Zhang","year":"2016","unstructured":"Zhang R, Chen S, Zhang H, Wang W, Xing J, Wang Y, et al. Biomarkers investigation for in-hospital death in patients with stanford Type A acute aortic dissection. Int Heart J. 2016;57(5):622\u20136. https:\/\/doi.org\/10.1536\/ihj.15-484.","journal-title":"Int Heart J"},{"issue":"2","key":"2538_CR23","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1016\/j.athoracsur.2004.02.091","volume":"78","author":"YF Chen","year":"2004","unstructured":"Chen YF, Tsai WC, Lin CC, Tsai LY, Lee CS, Huang CH, et al. Effect of leukocyte depletion on endothelial cell activation and transendothelial migration of leukocytes during cardiopulmonary bypass. Ann Thorac Surg. 2004;78(2):634\u201342. https:\/\/doi.org\/10.1016\/j.athoracsur.2004.02.091.","journal-title":"Ann Thorac Surg."},{"issue":"6","key":"2538_CR24","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.amjsurg.2003.09.001","volume":"186","author":"AN Patel","year":"2003","unstructured":"Patel AN, Sutton SW, Livingston S, Patel A, Hunley EK, Hebeler RF, et al. Clinical benefits of leukocyte filtration during valve surgery. Am J Surg. 2003;186(6):636\u20139. https:\/\/doi.org\/10.1016\/j.amjsurg.2003.09.001.","journal-title":"Am J Surg."},{"issue":"5","key":"2538_CR25","doi-asserted-by":"publisher","first-page":"2333","DOI":"10.21037\/jtd.2020.03.84","volume":"12","author":"R Yao","year":"2020","unstructured":"Yao R, Liu X, He Y, Mei C, Shen Y, Zhan Q, et al. Low platelet count is a risk factor of postoperative pneumonia in patients with type A acute aortic dissection. J Thorac Dis. 2020;12(5):2333\u201342. https:\/\/doi.org\/10.21037\/jtd.2020.03.84.","journal-title":"J Thorac Dis"},{"issue":"10","key":"2538_CR26","doi-asserted-by":"publisher","first-page":"2746","DOI":"10.1053\/j.jvca.2019.02.013","volume":"33","author":"I Zindovic","year":"2019","unstructured":"Zindovic I, Sj\u00f6gren J, Bjursten H, Ingemansson R, Ingimarsson J, Larsson M, et al. The coagulopathy of acute Type A aortic dissection: a prospective. Observ Study J Cardiothorac Vasc Anesth. 2019;33(10):2746\u201354. https:\/\/doi.org\/10.1053\/j.jvca.2019.02.013.","journal-title":"Observ Study J Cardiothorac Vasc Anesth"},{"issue":"3","key":"2538_CR27","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1016\/j.athoracsur.2015.08.047","volume":"101","author":"XL Guan","year":"2016","unstructured":"Guan XL, Wang XL, Liu YY, Lan F, Gong M, Li HY, et al. Changes in the hemostatic system of patients with acute aortic dissection undergoing aortic arch surgery. Ann Thorac Surg. 2016;101(3):945\u201351. https:\/\/doi.org\/10.1016\/j.athoracsur.2015.08.047.","journal-title":"Ann Thorac Surg"},{"key":"2538_CR28","doi-asserted-by":"publisher","unstructured":"Luc NF, Rohner N, Girish A, Didar Singh Sekhon U, Neal MD, SenGupta A. Bioinspired artificial platelets: past, present and future. Platelets. 2021: doi: https:\/\/doi.org\/10.1080\/09537104.2021.1967916.","DOI":"10.1080\/09537104.2021.1967916"},{"issue":"3","key":"2538_CR29","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1097\/aln.0000000000001518","volume":"126","author":"FM van Hout","year":"2017","unstructured":"van Hout FM, Hogervorst EK, Rosseel PM, van der Bom JG, Bentala M, van Dorp EL, et al. Does a platelet transfusion independently affect bleeding and adverse outcomes in cardiac surgery? Anesthesiology. 2017;126(3):441\u20139. https:\/\/doi.org\/10.1097\/aln.0000000000001518.","journal-title":"Anesthesiology"},{"issue":"2","key":"2538_CR30","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1097\/ta.0000000000002331","volume":"87","author":"LZ Kornblith","year":"2019","unstructured":"Kornblith LZ, Robles AJ, Conroy AS, Redick BJ, Howard BM, Hendrickson CM, et al. Predictors of postinjury acute respiratory distress syndrome: lung injury persists in the era of hemostatic resuscitation. J Trauma Acute Care Surg. 2019;87(2):371\u20138. https:\/\/doi.org\/10.1097\/ta.0000000000002331.","journal-title":"J Trauma Acute Care Surg"},{"key":"2538_CR31","doi-asserted-by":"publisher","first-page":"150","DOI":"10.2741\/3236","volume":"14","author":"A Zarbock","year":"2009","unstructured":"Zarbock A, Ley K. The role of platelets in acute lung injury (ALI). Front Biosci (Landmark Ed). 2009;14:150\u20138. https:\/\/doi.org\/10.2741\/3236.","journal-title":"Front Biosci (Landmark Ed)"},{"issue":"4","key":"2538_CR32","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1213\/ane.0b013e3181948a59","volume":"108","author":"IT Pereboom","year":"2009","unstructured":"Pereboom IT, de Boer MT, Haagsma EB, Hendriks HG, Lisman T, Porte RJ. Platelet transfusion during liver transplantation is associated with increased postoperative mortality due to acute lung injury. Anesth Analg. 2009;108(4):1083\u201391. https:\/\/doi.org\/10.1213\/ane.0b013e3181948a59.","journal-title":"Anesth Analg"},{"issue":"4","key":"2538_CR33","first-page":"497","volume":"48","author":"J Bingyang","year":"2007","unstructured":"Bingyang J, Jinping L, Mingzheng L, Guyan W, Zhengyi F. Effects of urinary protease inhibitor on inflammatory response during on-pump coronary revascularization. Effect of ulinastatin on inflammatory response. J Cardiovasc Surg (Torino). 2007;48(4):497\u2013503.","journal-title":"J Cardiovasc Surg (Torino)."},{"issue":"3","key":"2538_CR34","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.transci.2009.08.001","volume":"42","author":"CR Valeri","year":"2010","unstructured":"Valeri CR, Ragno G. An approach to prevent the severe adverse events associated with transfusion of FDA-approved blood products. Transfus Apher Sci. 2010;42(3):223\u201333. https:\/\/doi.org\/10.1016\/j.transci.2009.08.001.","journal-title":"Transfus Apher Sci"},{"issue":"6","key":"2538_CR35","first-page":"719","volume":"83","author":"S Sharma","year":"2011","unstructured":"Sharma S, Sharma P, Tyler LN. Transfusion of blood and blood products: indications and complications. Am Fam Physician. 2011;83(6):719\u201324.","journal-title":"Am Fam Physician"},{"key":"2538_CR36","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.jss.2018.06.048","volume":"232","author":"SS Naeem","year":"2018","unstructured":"Naeem SS, Sodha NR, Sellke FW, Ehsan A. Impact of packed red blood cell and platelet transfusions in patients undergoing dissection repair. J Surg Res. 2018;232:338\u201345. https:\/\/doi.org\/10.1016\/j.jss.2018.06.048.","journal-title":"J Surg Res"},{"issue":"22","key":"2538_CR37","doi-asserted-by":"publisher","first-page":"2133","DOI":"10.1056\/NEJMoa1711818","volume":"377","author":"CD Mazer","year":"2017","unstructured":"Mazer CD, Whitlock RP, Fergusson DA, Hall J, Belley-Cote E, Connolly K, et al. Restrictive or liberal red-cell transfusion for cardiac surgery. N Engl J Med. 2017;377(22):2133\u201344. https:\/\/doi.org\/10.1056\/NEJMoa1711818.","journal-title":"N Engl J Med"},{"issue":"26","key":"2538_CR38","doi-asserted-by":"publisher","first-page":"2453","DOI":"10.1056\/NEJMoa1012452","volume":"365","author":"JL Carson","year":"2011","unstructured":"Carson JL, Terrin ML, Noveck H, Sanders DW, Chaitman BR, Rhoads GG, et al. Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med. 2011;365(26):2453\u201362. https:\/\/doi.org\/10.1056\/NEJMoa1012452.","journal-title":"N Engl J Med"},{"issue":"6","key":"2538_CR39","doi-asserted-by":"publisher","first-page":"2288","DOI":"10.1016\/j.jtcvs.2019.04.111","volume":"159","author":"HK Sandhu","year":"2020","unstructured":"Sandhu HK, Tanaka A, Dahotre S, Charlton-Ouw KM, Miller CC 3rd, Estrera AL, et al. Propensity and impact of autologous platelet rich plasma use in acute type A dissection. J Thorac Cardiovasc Surg. 2020;159(6):2288\u201397. https:\/\/doi.org\/10.1016\/j.jtcvs.2019.04.111.","journal-title":"J Thorac Cardiovasc Surg."},{"issue":"6","key":"2538_CR40","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1016\/j.jamcollsurg.2012.03.005","volume":"214","author":"J Devarajan","year":"2012","unstructured":"Devarajan J, Vydyanathan A, Xu M, Murthy SM, McCurry KR, Sessler DI, et al. Early tracheostomy is associated with improved outcomes in patients who require prolonged mechanical ventilation after cardiac surgery. J Am Coll Surg. 2012;214(6):1008-16.e4. https:\/\/doi.org\/10.1016\/j.jamcollsurg.2012.03.005.","journal-title":"J Am Coll Surg"}],"container-title":["BMC Cardiovascular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-022-02538-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12872-022-02538-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-022-02538-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T16:20:49Z","timestamp":1646842849000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccardiovascdisord.biomedcentral.com\/articles\/10.1186\/s12872-022-02538-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,9]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["2538"],"URL":"https:\/\/doi.org\/10.1186\/s12872-022-02538-4","relation":{},"ISSN":["1471-2261"],"issn-type":[{"value":"1471-2261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,9]]},"assertion":[{"value":"5 January 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted in accordance with ethical statement of the Declaration of Helsinki and was approved by The Ethics Committee of Tongji Medical College of Huazhong University of Science and Technology (IORG No. IORG0003571). The requirement of written informed consent was waived by The Ethics Committee of Tongji Medical College of Huazhong University of Science and Technology (IORG No. IORG0003571) due to its observational, retrospective nature.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"94"}}