{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:20:11Z","timestamp":1792102811445,"version":"4.4.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T00:00:00Z","timestamp":1649462400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T00:00:00Z","timestamp":1649462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100014996","name":"Health and Family Planning Commission of Zhejiang Province","doi-asserted-by":"crossref","award":["No. 2018KY070"],"award-info":[{"award-number":["No. 2018KY070"]}],"id":[{"id":"10.13039\/501100014996","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Zhejiang Provincial Natural Science Foundation, P. R. China","award":["No LSD19H180002"],"award-info":[{"award-number":["No LSD19H180002"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cardiovasc Disord"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Large pulmonary valve perforation, which is rarely seen with infective endocarditis, general atrophy, or congenital fenestration, often leads to potentially fatal outcomes, including heart failure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>Transthoracic and transesophageal echocardiographic evaluation of a 69-year-old woman revealed a severely eccentric pulmonary regurgitation with concomitant pulmonary valve stenosis, patent ductus arteriosus, patent foramen ovale, and pulmonary artery aneurysm. In the operation, a large perforation was found in the pulmonary valve leaflet. She underwent complicated surgery that involved closure of the congenital heart defects and replacement of a pulmonary valve with successful results. But the cause of her pulmonary valve perforation remained undetermined.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>This case highlights two important points: the need for timely management of congenital heart disease and being aware of the possibility of pulmonary valve perforation, which in this case was indicated by an eccentric pulmonary regurgitant jet seen on echocardiography.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12872-022-02595-9","type":"journal-article","created":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T08:02:40Z","timestamp":1649491360000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pulmonary valve perforation with multiple cardiac anomalies: a case report"],"prefix":"10.1186","volume":"22","author":[{"given":"Yan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanhuan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8704-3331","authenticated-orcid":false,"given":"Yun","family":"Mou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhelan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,9]]},"reference":[{"key":"2595_CR1","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/0002-8703(85)90563-0","volume":"109","author":"RS Cassling","year":"1985","unstructured":"Cassling RS, Rogler WC, McManus BM. Isolated pulmonic valve infective endocarditis: a diagnostically elusive entity. Am Heart J. 1985;109:558\u201367.","journal-title":"Am Heart J"},{"issue":"4","key":"2595_CR2","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/0002-9343(58)90295-X","volume":"24","author":"B Friedman","year":"1958","unstructured":"Friedman B, Hathaway BM. Fenestration of the semilunar cusps, and functional aortic and pulmonic valve insufficiency. Am J Med. 1958;24(4):549\u201358.","journal-title":"Am J Med"},{"issue":"6","key":"2595_CR3","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1097\/01.SMJ.0000047965.45842.A2","volume":"96","author":"M Tariq","year":"2003","unstructured":"Tariq M, Smego RA Jr, Soofi A, Islam N. Pulmonic valve endocarditis. South Med J. 2003;96(6):621\u20133.","journal-title":"South Med J"},{"key":"2595_CR4","first-page":"8268296","volume":"2019","author":"VR Ramiro","year":"2019","unstructured":"Ramiro VR, Taquiso JL, Obillos SMO, Agustin CF, Magno JDA, Sison EOD. Pulmonary artery and pulmonic valve vegetations in a young pregnant filipino with patent ductus arteriosus. Case Rep Cardiol. 2019;2019:8268296.","journal-title":"Case Rep Cardiol"},{"issue":"9","key":"2595_CR5","doi-asserted-by":"publisher","first-page":"608","DOI":"10.3390\/medicina55090608","volume":"55","author":"D Liekiene","year":"2019","unstructured":"Liekiene D, Bezuska L, Semeniene P, Cypiene R, Lebetkevicius V, Tarutis V, et al. surgical treatment of infective endocarditis in pulmonary position-15 years single centre experience. Medicina (Kaunas). 2019;55(9):608.","journal-title":"Medicina (Kaunas)"},{"issue":"2","key":"2595_CR6","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1177\/2150135119896287","volume":"11","author":"KM Corey","year":"2020","unstructured":"Corey KM, Campbell MJ, Hill KD, Hornik CP, Krasuski R, Barker PC, et al. Pulmonary valve endocarditis: the potential utility of multimodal imaging prior to surgery. World J Pediatr Congenit Heart Surg. 2020;11(2):192\u20137.","journal-title":"World J Pediatr Congenit Heart Surg"},{"issue":"1","key":"2595_CR7","doi-asserted-by":"publisher","first-page":"204589402090878","DOI":"10.1177\/2045894020908780","volume":"10","author":"M Gupta","year":"2020","unstructured":"Gupta M, Agrawal A, Iakovou A, Cohen S, Shah R, Talwar A. Pulmonary artery aneurysm: a review. Pulm Circ. 2020;10(1):2045894020908780.","journal-title":"Pulm Circ"},{"issue":"3","key":"2595_CR8","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1161\/CIRCULATIONAHA.114.012907","volume":"131","author":"M Kreibich","year":"2015","unstructured":"Kreibich M, Siepe M, Kroll J, H\u00f6hn R, Grohmann J, Beyersdorf F. Aneurysms of the pulmonary artery. Circulation. 2015;131(3):310\u20136.","journal-title":"Circulation"}],"container-title":["BMC Cardiovascular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-022-02595-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12872-022-02595-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-022-02595-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T08:04:57Z","timestamp":1649491497000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccardiovascdisord.biomedcentral.com\/articles\/10.1186\/s12872-022-02595-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,9]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["2595"],"URL":"https:\/\/doi.org\/10.1186\/s12872-022-02595-9","relation":{},"ISSN":["1471-2261"],"issn-type":[{"value":"1471-2261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,9]]},"assertion":[{"value":"15 May 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 April 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was approved by the Institutional Review Board at the First Affiliated Hospital, College of Medicine, Zhejiang University. And the procedures were conducted according to the principles of the Helsinki Declaration.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Written informed consent was obtained from the patient for the publication of this case report and any accompanying figure.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"159"}}