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The shift in health-care resources from communicable diseases to chronic conditions has created formidable health-care challenges.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study was to examine the knowledge, attitudes and beliefs among ACS patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross-sectional design was used to enroll participants admitted to one of 3 emergency units in Addis Ababa, Ethiopia. Knowledge, attitudes and beliefs about ACS was measured using modified ACS response index questionaries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Participant\u2019s (N\u2009=\u2009330) mean age was 57.9\u2009\u00b1\u200914.1, majority male (n\u2009=\u2009219, 66.36%). Half of the study participants have inadequate Knowledge (n\u2009=\u2009147, 44.6%), unfavorable attitudes (n\u2009=\u2009152, 46%), and belief (n\u2009=\u2009153, 46.4%) about ACS symptoms even after being diagnosed and treated in the emergency unit. The most frequently recognized ACS symptoms were chest discomfort (n\u2009=\u2009274, 83%), fatigue (n\u2009=\u2009267, 80.9%) and chest pain (n\u2009=\u2009266, 80.6%) while Jaw pain (n\u2009=\u2009101, 30%) neck pain (n\u2009=\u2009146,44.2%), were less often recognized. Nearly two thirds of the participants (n\u2009=\u2009214, 65%) would not prefer to use emergency medical services (EMS) to come to the hospital. Factors associated with adequate knowledge were age\u2009&lt;\u200945 (AOR\u2009=\u20092.16, CI (1.1\u20134.0) p\u2009=\u20090.014), and female sex (AOR\u2009=\u20092.7, CI (1.5\u20134.4) p\u2009=\u20090.001) and diabetics (AOR\u2009=\u20091.9, (1.18\u20133.0) p\u2009=\u20090.008). Meanwhile, lack of formal education (AOR\u2009=\u20096.7, CI (3.1\u201314) p\u2009&lt;\u20090.001) and unemployment (AOR\u2009=\u20092.0, CI (1.1\u20133.8) p\u2009=\u20090.021) were associated with unfavorable attitude. In addition, lack of social support (AOR\u2009=\u20091.9, (1.17\u20133.0) p\u2009=\u20090.009) and unfavorable attitude (AOR\u2009=\u20092.1, CI (1.3\u20133.4) p\u2009=\u20090.001) were significantly associated with unfavorable belief.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite receiving treatment for ACS in an emergency unit, roughly half of participants did not have adequate knowledge, favorable attitude and belief towards ACS. This elucidates there is significant communication gap between the health care providers and patients. The study findings stipulate there is a need to provide health awareness campaigns using different media outlet with special attention to the uneducated and unemployed groups. Furthermore, most participants were less likely to utilize emergency medical service, which should be further investigated and addressed.<\/jats:p><\/jats:sec>","DOI":"10.1186\/s12872-022-02893-2","type":"journal-article","created":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T07:03:39Z","timestamp":1665731019000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Knowledge, attitudes and beliefs about acute coronary syndrome among patients diagnosed with acute coronary syndrome, Addis Ababa, Ethiopia"],"prefix":"10.1186","volume":"22","author":[{"given":"Lemlem","family":"Demisse","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bekele","family":"Alemayehu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adamu","family":"Addissie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aklilu","family":"Azazh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Gary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,10,14]]},"reference":[{"issue":"24","key":"2893_CR1","doi-asserted-by":"publisher","first-page":"e139","DOI":"10.1016\/j.jacc.2014.09.017","volume":"64","author":"EA Amsterdam","year":"2014","unstructured":"Amsterdam EA, et al. 2014 AHA\/ACC guideline for the management of patients with non\u2013ST-elevation acute coronary syndromes: a report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines. 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The purpose, general content and nature of the study was explained in the language preferred by the study participant and informed consent was obtained from all participant prior to the data collection. The participants were informed that they had the right to be involved or refuse to participate in the study and the right to withdraw from the study at any time during the interview. They were also assured that the data would be handled exclusively by the investigators and used only for the purpose of the study. In addition, the confidentiality of the information obtained from each participant was maintained. 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