{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T07:23:26Z","timestamp":1793604206959,"version":"4.5.0"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T00:00:00Z","timestamp":1672358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T00:00:00Z","timestamp":1672358400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cardiovasc Disord"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Atrial myxomas account for approximately 50% of all primary cardiac tumors. The size, location, risk of embolic event, and involvement of other cardiac structures, are all factors that contribute to the wide range of presentation for cardiac myxomas. Patients with myxomas may remain asymptomatic, while others may report symptoms such as fatigue and fever, dyspnea, and syncope. It is important to recognize arrhythmias as an uncommon symptom of myxomas.\n<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We report a rare case of a 67-year-old man who presented with pre-syncopal episodes, symptomatic bradycardia, and night sweats found to have a 5.5\u2009\u00d7\u20095.1\u2009\u00d7\u20093\u00a0cm myxoma in the left atrium. During diastole the mass caused dynamic flow obstruction across the mitral valve. The patient underwent surgical resection of the mass given his symptomatology and risk of embolic events. Removal of the myxoma resulted in resolution of both pre-syncopal episodes and the patient\u2019s sinus bradycardia.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Atrial myxomas are a rare cause of pre-syncope and symptomatic bradycardia. It is important to have a clinical suspicion for atrial myxomas given early diagnosis and surgical intervention are key in improving the prognosis of these patients. This case also highlights the importance of taking into account the source of the myxoma\u2019s blood supply in relationship to other cardiac structures, and further correlating these findings with clinical symptoms.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12872-022-03018-5","type":"journal-article","created":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T11:02:56Z","timestamp":1672398176000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Left atrial myxoma: an unusual cause of pre-syncope and symptomatic bradycardia"],"prefix":"10.1186","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2852-4127","authenticated-orcid":false,"given":"Kenny","family":"Vongbunyong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Sinfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ned","family":"Premyodhin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emin","family":"Zargarian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angie","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morton","family":"Kern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,30]]},"reference":[{"issue":"12","key":"3018_CR1","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/s11886-020-01420-z","volume":"22","author":"R Bussani","year":"2020","unstructured":"Bussani R, Castrichini M, Restivo L, et al. Cardiac tumors: diagnosis, prognosis, and treatment. Curr Cardiol Rep. 2020;22(12):169. https:\/\/doi.org\/10.1007\/s11886-020-01420-z.","journal-title":"Curr Cardiol Rep"},{"issue":"1","key":"3018_CR2","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.jsha.2016.07.003","volume":"29","author":"B Thyagarajan","year":"2017","unstructured":"Thyagarajan B, Kumar MP, Patel S, Agrawal A. Extracardiac manifestations of atrial myxomas. J Saudi Heart Assoc. 2017;29(1):37\u201343. https:\/\/doi.org\/10.1016\/j.jsha.2016.07.003.","journal-title":"J Saudi Heart Assoc"},{"issue":"4","key":"3018_CR3","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1002\/joa3.12030","volume":"34","author":"S Jayaprakash","year":"2018","unstructured":"Jayaprakash S. Clinical presentations, diagnosis, and management of arrhythmias associated with cardiac tumors. J Arrhythm. 2018;34(4):384\u201393. https:\/\/doi.org\/10.1002\/joa3.12030.","journal-title":"J Arrhythm"},{"issue":"1","key":"3018_CR4","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.jsha.2010.07.007","volume":"23","author":"AS Omran","year":"2011","unstructured":"Omran AS, Arifi AA, Mohamed AA. Echocardiography in mitral stenosis. J Saudi Heart Assoc. 2011;23(1):51\u20138. https:\/\/doi.org\/10.1016\/j.jsha.2010.07.007.","journal-title":"J Saudi Heart Assoc"},{"issue":"3","key":"3018_CR5","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1097\/00005792-200105000-00002","volume":"80","author":"L Pinede","year":"2001","unstructured":"Pinede L, Duhaut P, Loire R. Clinical presentation of left atrial cardiac myxoma. A series of 112 consecutive cases. Medicine. 2001;80(3):159\u201372. https:\/\/doi.org\/10.1097\/00005792-200105000-00002.","journal-title":"Medicine"},{"key":"3018_CR6","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1007\/s00059-013-3930-z","volume":"40","author":"H Omar","year":"2015","unstructured":"Omar H. The value of coronary angiography in the workup of myxomas. Herz. 2015;40:442\u20136.","journal-title":"Herz"},{"issue":"4","key":"3018_CR7","doi-asserted-by":"publisher","first-page":"603","DOI":"10.31688\/ABMU.2018.53.4.20","volume":"53","author":"E Dobrica","year":"2018","unstructured":"Dobrica E, Gaman M, Cozma M, Gherghiceanu F, Stoian A, Socea B, et al. Sinus bradycardia in a young female. Arch Balk Med Union. 2018;53(4):603\u20137.","journal-title":"Arch Balk Med Union"},{"issue":"4","key":"3018_CR8","doi-asserted-by":"publisher","first-page":"E200","DOI":"10.1532\/HSF98.20111180","volume":"15","author":"Z Bayramo\u011flu","year":"2012","unstructured":"Bayramo\u011flu Z, Caynak B, Oral K, Erdim R, Teyyareci Y, Akp\u0131nar B. Left atrial myxoma with neovascularization presenting as a sick sinus syndrome. Heart Surg Forum. 2012;15(4):E200\u20133. https:\/\/doi.org\/10.1532\/HSF98.20111180.","journal-title":"Heart Surg Forum"}],"container-title":["BMC Cardiovascular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-022-03018-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12872-022-03018-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-022-03018-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T11:05:25Z","timestamp":1672398325000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccardiovascdisord.biomedcentral.com\/articles\/10.1186\/s12872-022-03018-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,30]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["3018"],"URL":"https:\/\/doi.org\/10.1186\/s12872-022-03018-5","relation":{},"ISSN":["1471-2261"],"issn-type":[{"value":"1471-2261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,30]]},"assertion":[{"value":"21 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The patient has provided consent for the included medical information, and has filed out a consent form to participate in the case.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The patient has provided consent regarding the publication of this case report and has signed a consent form.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that there are no competing or conflicts of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"576"}}