{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T15:17:35Z","timestamp":1793114255710,"version":"4.5.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Cardiovasc Disord"],"DOI":"10.1186\/s12872-025-04794-6","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T02:30:05Z","timestamp":1745980205000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of TyG and modified TyG indices in predicting coronary slow flow phenomenon"],"prefix":"10.1186","volume":"25","author":[{"given":"Jing","family":"Nan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruofei","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingsheng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zening","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"issue":"22","key":"4794_CR1","first-page":"e368","volume":"144","author":"M Gulati","year":"2021","unstructured":"Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA\/ACC\/ASE\/CHEST\/SAEM\/SCCT\/SCMR guideline for the evaluation and diagnosis of chest pain: executive summary: A report of the American college of cardiology\/american heart association joint committee on clinical practice guidelines. Circulation. 2021;144(22):e368\u2013454.","journal-title":"Circulation"},{"issue":"20","key":"4794_CR2","doi-asserted-by":"publisher","first-page":"1925","DOI":"10.1016\/j.jacc.2022.08.750","volume":"80","author":"MC Kontos","year":"2022","unstructured":"Kontos MC, de Lemos JA, Deitelzweig SB, et al. 2022 ACC expert consensus decision pathway on the evaluation and disposition of acute chest pain in the emergency department: A report of the American college of cardiology solution set oversight committee. J Am Coll Cardiol. 2022;80(20):1925\u201360.","journal-title":"J Am Coll Cardiol"},{"issue":"1","key":"4794_CR3","first-page":"21","volume":"13","author":"M Asadi Anar","year":"2023","unstructured":"Asadi Anar M, Ansari A, Erabi G, et al. Prognostic value of fragmented QRS in acute pulmonary embolism: a cross-sectional-analytic study of the Iranian population. Am J Cardiovasc Dis. 2023;13(1):21\u20138.","journal-title":"Am J Cardiovasc Dis"},{"key":"4794_CR4","doi-asserted-by":"publisher","unstructured":"Sajjadi S, Mohebbi A, Ehsani A et al. Identifying abdominal aortic aneurysm size and presence using natural Language processing of radiology reports: a systematic review and meta-analysis. Abdom Radiol.2025. https:\/\/doi.org\/10.1007\/s00261-025-04810-5","DOI":"10.1007\/s00261-025-04810-5"},{"issue":"17","key":"4794_CR5","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1056\/NEJMoa2200963","volume":"386","author":"P Maurovich-Horvat","year":"2022","unstructured":"Maurovich-Horvat P, Bosserdt M, Kofoed KF, et al. CT or invasive coronary angiography in stable chest pain. N Engl J Med. 2022;386(17):1591\u2013602.","journal-title":"N Engl J Med"},{"key":"4794_CR6","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.atherosclerosis.2022.11.009","volume":"363","author":"PK Mehta","year":"2022","unstructured":"Mehta PK, Huang J, Levit RD, et al. Ischemia and no obstructive coronary arteries (INOCA): A narrative review. Atherosclerosis. 2022;363:8\u201321.","journal-title":"Atherosclerosis"},{"issue":"9","key":"4794_CR7","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1177\/00033197211004390","volume":"72","author":"G Chalikias","year":"2021","unstructured":"Chalikias G, Tziakas D. Slow coronary flow: pathophysiology, clinical implications, and therapeutic management. Angiology. 2021;72(9):808\u201318.","journal-title":"Angiology"},{"key":"4794_CR8","doi-asserted-by":"publisher","first-page":"232470961878919","DOI":"10.1177\/2324709618789194","volume":"6","author":"C Alvarez","year":"2018","unstructured":"Alvarez C, Siu H. Coronary Slow-Flow phenomenon as an underrecognized and treatable source of chest pain: case series and literature review. J Investig Med High Impact Case Rep. 2018;6:2324709618789194.","journal-title":"J Investig Med High Impact Case Rep"},{"key":"4794_CR9","doi-asserted-by":"publisher","first-page":"155511","DOI":"10.1016\/j.cyto.2021.155511","volume":"143","author":"N Roshanravan","year":"2021","unstructured":"Roshanravan N, Shabestari AN, Alamdari NM, et al. A novel inflammatory signaling pathway in patients with slow coronary flow: NF-\u03baB\/IL-1\u03b2\/nitric oxide. Cytokine. 2021;143:155511.","journal-title":"Cytokine"},{"issue":"1","key":"4794_CR10","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1186\/s12872-022-02798-0","volume":"22","author":"XT Dai","year":"2022","unstructured":"Dai XT, Kong TZ, Zhang XJ, et al. Relationship between increased systemic immune-inflammation index and coronary slow flow phenomenon. BMC Cardiovasc Disord. 2022;22(1):362.","journal-title":"BMC Cardiovasc Disord"},{"issue":"1","key":"4794_CR11","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1186\/s12872-023-03564-6","volume":"23","author":"B Zhang","year":"2023","unstructured":"Zhang B, Peng A, Li S, et al. Association of triglyceride-glucose index and neutrophil-to-lymphocyte ratio with coronary artery disease. BMC Cardiovasc Disord. 2023;23(1):534.","journal-title":"BMC Cardiovasc Disord"},{"issue":"1","key":"4794_CR12","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1186\/s12933-022-01606-5","volume":"21","author":"E Xie","year":"2022","unstructured":"Xie E, Ye Z, Wu Y, et al. Association between the triglyceride-glucose index and severity of coronary artery disease. Cardiovasc Diabetol. 2022;21(1):168.","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"4794_CR13","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1186\/s12933-024-02230-1","volume":"23","author":"W Zhang","year":"2024","unstructured":"Zhang W, Liu L, Yin G, et al. Triglyceride-glucose index is associated with myocardial ischemia and poor prognosis in patients with ischemia and no obstructive coronary artery disease. Cardiovasc Diabetol. 2024;23(1):187.","journal-title":"Cardiovasc Diabetol"},{"issue":"6","key":"4794_CR14","doi-asserted-by":"publisher","first-page":"e20220679","DOI":"10.36660\/abc.20220679","volume":"120","author":"M Kaplangoray","year":"2023","unstructured":"Kaplangoray M, Toprak K, Ba\u015fanalan F, et al. Investigation of the relationship between Triglycerides-Glucose index and coronary slow flow: A retrospective Case-Control study. Arq Bras Cardiol. 2023;120(6):e20220679.","journal-title":"Arq Bras Cardiol"},{"issue":"8","key":"4794_CR15","first-page":"3016","volume":"28","author":"MN Bilen","year":"2024","unstructured":"Bilen MN, Barman HA, Dogan O, et al. The triglyceride-glucose index as a predictive marker for coronary slow flow phenomenon. Eur Rev Med Pharmacol Sci. 2024;28(8):3016\u201323.","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"5","key":"4794_CR16","doi-asserted-by":"publisher","first-page":"62","DOI":"10.18087\/cardio.2023.5.n2296","volume":"63","author":"Y Yuksel","year":"2023","unstructured":"Yuksel Y, Yildiz C. Evaluation of triglyceride-glucose index in coronary slow flow patients. Kardiologiia. 2023;63(5):62\u20137.","journal-title":"Kardiologiia"},{"issue":"8","key":"4794_CR17","first-page":"585","volume":"123","author":"I Buber","year":"2022","unstructured":"Buber I, Nar R, Kaya D, et al. Assessment of triglyceride\/glucose index with respect to coronary slow flow. Bratisl Lek Listy. 2022;123(8):585\u20138.","journal-title":"Bratisl Lek Listy"},{"issue":"1","key":"4794_CR18","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1186\/s40001-024-01820-9","volume":"29","author":"SH Ahn","year":"2024","unstructured":"Ahn SH, Lee HS, Lee JH. Triglyceride-glucose-waist circumference index predicts the incidence of cardiovascular disease in Korean populations: competing risk analysis of an 18-year prospective study. Eur J Med Res. 2024;29(1):214.","journal-title":"Eur J Med Res"},{"issue":"1","key":"4794_CR19","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s12872-024-03722-4","volume":"24","author":"ZP Li","year":"2024","unstructured":"Li ZP, Chen J, Xin Q, et al. Triglyceride glucose-body mass index as a novel predictor of slow coronary flow phenomenon in patients with ischemia and nonobstructive coronary arteries (INOCA). BMC Cardiovasc Disord. 2024;24(1):60.","journal-title":"BMC Cardiovasc Disord"},{"issue":"1","key":"4794_CR20","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1186\/s12933-023-02047-4","volume":"22","author":"J Dou","year":"2023","unstructured":"Dou J, Guo C, Wang Y, et al. Association between triglyceride glucose-body mass and one-year all-cause mortality of patients with heart failure: a retrospective study utilizing the MIMIC-IV database. Cardiovasc Diabetol. 2023;22(1):309.","journal-title":"Cardiovasc Diabetol"},{"issue":"1","key":"4794_CR21","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1186\/s12944-024-02155-4","volume":"23","author":"Y Zhuang","year":"2024","unstructured":"Zhuang Y, Wang Y, Sun P, et al. Association between triglyceride glucose-waist to height ratio and coronary heart disease: a population-based study. Lipids Health Dis. 2024;23(1):162.","journal-title":"Lipids Health Dis"},{"issue":"11","key":"4794_CR22","doi-asserted-by":"publisher","first-page":"e70050","DOI":"10.1002\/clc.70050","volume":"47","author":"L Han","year":"2024","unstructured":"Han L, Li M, Xie W, et al. Association between orthostatic hypotension with coronary slow flow in patients with chest pain: A single center experience. Clin Cardiol. 2024;47(11):e70050.","journal-title":"Clin Cardiol"},{"issue":"6","key":"4794_CR23","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1159\/000533802","volume":"148","author":"G Ipek","year":"2023","unstructured":"Ipek G, Kamber T, Yilmaz H, et al. Long-Term change in flow rates in patients with coronary slow flow. Cardiology. 2023;148(6):500\u20135.","journal-title":"Cardiology"},{"issue":"5","key":"4794_CR24","doi-asserted-by":"publisher","first-page":"986","DOI":"10.47391\/JPMA.22-63","volume":"72","author":"VK Ramdas Nayak","year":"2022","unstructured":"Ramdas Nayak VK, Satheesh P, Shenoy MT, et al. Triglyceride glucose (TyG) index: A surrogate biomarker of insulin resistance. J Pak Med Assoc. 2022;72(5):986\u20138.","journal-title":"J Pak Med Assoc"},{"issue":"1","key":"4794_CR25","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1186\/s12933-024-02241-y","volume":"23","author":"JL Yin","year":"2024","unstructured":"Yin JL, Yang J, Song XJ, et al. Triglyceride-glucose index and health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies. Cardiovasc Diabetol. 2024;23(1):177.","journal-title":"Cardiovasc Diabetol"},{"key":"4794_CR26","doi-asserted-by":"publisher","first-page":"951689","DOI":"10.3389\/fendo.2022.951689","volume":"13","author":"Y Xue","year":"2022","unstructured":"Xue Y, Xu J, Li M, et al. Potential screening indicators for early diagnosis of NAFLD\/MAFLD and liver fibrosis: triglyceride glucose index-related parameters. Front Endocrinol (Lausanne). 2022;13:951689.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"1","key":"4794_CR27","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1186\/s12888-021-03275-2","volume":"21","author":"YY Shi","year":"2021","unstructured":"Shi YY, Zheng R, Cai JJ, et al. The association between triglyceride glucose index and depression: data from NHANES 2005\u20132018. BMC Psychiatry. 2021;21(1):267.","journal-title":"BMC Psychiatry"},{"issue":"1","key":"4794_CR28","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1186\/s12944-024-02008-0","volume":"23","author":"J Zhang","year":"2024","unstructured":"Zhang J, Yin B, Xi Y, et al. Triglyceride-glucose index is a risk factor for breast cancer in China: a cross-sectional study. Lipids Health Dis. 2024;23(1):29.","journal-title":"Lipids Health Dis"},{"issue":"1","key":"4794_CR29","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1186\/s12933-023-01794-8","volume":"22","author":"Y Cheng","year":"2023","unstructured":"Cheng Y, Fang Z, Zhang X, et al. Association between triglyceride glucose-body mass index and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study. Cardiovasc Diabetol. 2023;22(1):75.","journal-title":"Cardiovasc Diabetol"},{"key":"4794_CR30","doi-asserted-by":"publisher","first-page":"949831","DOI":"10.3389\/fendo.2022.949831","volume":"13","author":"W Xuan","year":"2022","unstructured":"Xuan W, Liu D, Zhong J, et al. Impacts of triglyceride Glucose-Waist to height ratio on diabetes incidence: A secondary analysis of A Population-Based longitudinal data. Front Endocrinol (Lausanne). 2022;13:949831.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"4","key":"4794_CR31","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1038\/s41440-023-01502-9","volume":"47","author":"H Miao","year":"2024","unstructured":"Miao H, Zhou Z, Yang S, et al. The association of triglyceride-glucose index and related parameters with hypertension and cardiovascular risk: a cross-sectional study. Hypertens Res. 2024;47(4):877\u201386.","journal-title":"Hypertens Res"},{"issue":"1","key":"4794_CR32","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1111\/jch.14758","volume":"26","author":"C Yang","year":"2024","unstructured":"Yang C, Song Y, Wang X, et al. Association of hypertension with the triglyceride-glucose index and its associated indices in the Chinese population: A 6-year prospective cohort study. J Clin Hypertens (Greenwich). 2024;26(1):53\u201362.","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"4794_CR33","doi-asserted-by":"publisher","first-page":"862919","DOI":"10.3389\/fendo.2022.862919","volume":"13","author":"X Li","year":"2022","unstructured":"Li X, Sun M, Yang Y, et al. Predictive effect of triglyceride Glucose-Related parameters, obesity indices, and lipid ratios for diabetes in a Chinese population: A prospective cohort study. Front Endocrinol (Lausanne). 2022;13:862919.","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"3","key":"4794_CR34","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.tcm.2022.12.001","volume":"34","author":"Q Zhu","year":"2024","unstructured":"Zhu Q, Wang S, Huang X, et al. Understanding the pathogenesis of coronary slow flow: recent advances. Trends Cardiovasc Med. 2024;34(3):137\u201344.","journal-title":"Trends Cardiovasc Med"},{"issue":"1","key":"4794_CR35","first-page":"904","volume":"15","author":"H Niu","year":"2018","unstructured":"Niu H, Wei Z, Zhang Y, et al. Atorvastatin improves coronary flow and endothelial function in patients with coronary slow flow. Exp Ther Med. 2018;15(1):904\u20138.","journal-title":"Exp Ther Med"},{"key":"4794_CR36","doi-asserted-by":"publisher","first-page":"106841","DOI":"10.1016\/j.vph.2021.106841","volume":"138","author":"C Zhao","year":"2021","unstructured":"Zhao C, Zong Z, Zhu Q, et al. The LncRNA MALAT1 participates in regulating coronary slow flow endothelial dysfunction through the miR-181b-5p-MEF2A-ET-1 axis. Vascul Pharmacol. 2021;138:106841.","journal-title":"Vascul Pharmacol"},{"issue":"12","key":"4794_CR37","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1253\/circj.67.1022","volume":"67","author":"A Camsarl","year":"2003","unstructured":"Camsarl A, Pekdemir H, Cicek D, et al. Endothelin-1 and nitric oxide concentrations and their response to exercise in patients with slow coronary flow. Circ J. 2003;67(12):1022\u20138.","journal-title":"Circ J"},{"issue":"1\u20132","key":"4794_CR38","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.cca.2007.05.024","volume":"385","author":"JJ Li","year":"2007","unstructured":"Li JJ, Qin XW, Li ZC, et al. Increased plasma C-reactive protein and interleukin-6 concentrations in patients with slow coronary flow. Clin Chim Acta. 2007;385(1\u20132):43\u20137.","journal-title":"Clin Chim Acta"},{"issue":"2","key":"4794_CR39","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.ijcard.2005.05.008","volume":"108","author":"H Turhan","year":"2006","unstructured":"Turhan H, Saydam GS, Erbay AR, et al. Increased plasma soluble adhesion molecules; ICAM-1, VCAM-1, and E-selectin levels in patients with slow coronary flow. Int J Cardiol. 2006;108(2):224\u201330.","journal-title":"Int J Cardiol"},{"issue":"4","key":"4794_CR40","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1159\/000099068","volume":"107","author":"H Tanriverdi","year":"2007","unstructured":"Tanriverdi H, Evrengul H, Enli Y, et al. Effect of homocysteine-induced oxidative stress on endothelial function in coronary slow-flow. Cardiology. 2007;107(4):313\u201320.","journal-title":"Cardiology"},{"issue":"1","key":"4794_CR41","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1007\/s12325-008-0011-4","volume":"25","author":"Y Enli","year":"2008","unstructured":"Enli Y, Turk M, Akbay R, et al. Oxidative stress parameters in patients with slow coronary flow. Adv Ther. 2008;25(1):37\u201344.","journal-title":"Adv Ther"},{"issue":"6","key":"4794_CR42","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1161\/CIRCULATIONAHA.107.699579","volume":"117","author":"RB D\u2019Agostino","year":"2008","unstructured":"D\u2019Agostino RB, Sr, Vasan RS, Pencina MJ, et al. General cardiovascular risk profile for use in primary care: the Framingham heart study. Circulation. 2008;117(6):743\u201353.","journal-title":"Circulation"},{"issue":"8","key":"4794_CR43","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1253\/circj.CJ-20-1075","volume":"85","author":"K Okumura","year":"2021","unstructured":"Okumura K, Tomita H, Nakai M, et al. A novel risk stratification system for ischemic stroke in Japanese patients with Non-Valvular atrial fibrillation. Circ J. 2021;85(8):1254\u201362.","journal-title":"Circ J"}],"container-title":["BMC Cardiovascular Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-025-04794-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12872-025-04794-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12872-025-04794-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T04:04:44Z","timestamp":1745985884000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmccardiovascdisord.biomedcentral.com\/articles\/10.1186\/s12872-025-04794-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,30]]},"references-count":43,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["4794"],"URL":"https:\/\/doi.org\/10.1186\/s12872-025-04794-6","relation":{},"ISSN":["1471-2261"],"issn-type":[{"value":"1471-2261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,30]]},"assertion":[{"value":"21 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This research was carried out in line with the Helsinki Declaration. Written informed consents were retrieved from patients and\/or their authorized relatives, and the ethical clearance was obtained from Beijing Tiantan Hospital, affiliated with Capital Medical University (KY-23-037). Due to the nature of our study, we did not registered this study so the clinical trial number was not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"All of the authors agree to publish this study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"340"}}