{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T06:00:14Z","timestamp":1775282414130,"version":"3.50.1"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:00:00Z","timestamp":1611273600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:00:00Z","timestamp":1611273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Emerg Med"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Failed airway management is the major contributor for anaesthesia-related morbidity and mortality. <jats:italic>Cannot-intubate-cannot-ventilate<\/jats:italic> scenarios are the most critical emergency in airway management, and belong to the worst imaginable scenarios in an anaesthetist\u2019s life. In such situations, apnoeic oxygenation might be useful to avoid hypoxaemia. Anaesthesia guidelines recommend careful preoxygenation and application of high flow oxygen in difficult intubation scenarios to prevent episodes of deoxygenation. In this study, we evaluated the decrease in oxygen concentration in a model when using different strategies of oxygenation: using a special oxygenation laryngoscope, nasal oxygen, nasal high flow oxygen, and control.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In this experimental study we compared no oxygen application as a control, standard pure oxygen application of 10\u2009l\u00b7min<jats:sup>\u2212\u20091<\/jats:sup> via nasal cannula, high flow 90% oxygen application at 20\u2009l\u00b7min<jats:sup>\u2212\u20091<\/jats:sup> using a special nasal high flow device, and pure oxygen application via our oxygenation laryngoscope at 10\u2009l\u00b7min<jats:sup>\u2212\u20091<\/jats:sup>. We preoxygenated a simulation lung to 97% oxygen concentration and connected this to the trachea of a manikin model simulating apnoeic oxygenation. Decrease in oxygen concentration in the simulation lung was measured continuously for 20\u2009min.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Oxygen concentration in the simulation lung dropped from 97\u2009\u00b1\u20091% at baseline to 40\u2009\u00b1\u20091% in the no oxygen group, to 80\u2009\u00b1\u20091% in the standard nasal oxygen group, and to 73\u2009\u00b1\u20092% in the high flow nasal oxygenation group. However, it remained at 96\u2009\u00b1\u20090% in the oxygenation laryngoscope group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 between all groups).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>In this technical simulation, oxygenation via oxygenation laryngoscope was more effective than standard oxygen insufflation via nasal cannula, which was more effective than nasal high flow insufflation of 90% oxygen.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12873-021-00407-5","type":"journal-article","created":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T08:03:37Z","timestamp":1611302617000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Oxygenation laryngoscope vs. nasal standard and nasal high flow oxygenation in a technical simulation of apnoeic oxygenation"],"prefix":"10.1186","volume":"21","author":[{"given":"H.","family":"Herff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5800-6665","authenticated-orcid":false,"given":"W. 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