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Invasive procedures may lead to various complications and the IVC ultrasound measurements are increasingly recognized as a potential noninvasive replacement or a source of adjunct information.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Aimof this study<\/jats:title>\n                <jats:p>The study aimed to determine if repeated ultrasound assessment of the inferior vena cava (diameter, collapsibility (IVC- CI) in major trauma patients presenting with collapsible IVC before resuscitation and after the first hour of resuscitation will predict total intravenous fluid requirements at first 24\u00a0h.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Patients &amp; methods<\/jats:title>\n                <jats:p>The current study was conducted on 120 patients presented to the emergency department with Major blunt trauma (having significant injury to two or more ISS body regions or an ISS greater than 15). The patients(cases) group (shocked group) (60) patients with signs of shock such as decreased blood pressure\u2009&lt;\u200990\/60\u00a0mmHg or a more than 30% decrease from the baseline systolic pressure, heart rate\u2009&gt;\u2009100 b\/m, cold, clammy skin, capillary refill\u2009&gt;\u20092\u00a0s and their shock index above0.9. The control group (non-shocked group) (60) patients with normal blood pressure and heart rate, no other signs of shock (normal capillary refill, warm skin), and (shock index\u2009\u2264\u20090.9). Patients were evaluated at time 0 (baseline), 1\u00a0h after resucitation, and 24\u00a0h after 1st hour for:(blood pressure, pulse, RR, SO2, capillary refill time, MABP, IVCci, IVCmax, IVCmin).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among 120 Major blunt trauma patients, 98 males (81.7%) and 22 females (18.3%) were included in this analysis; hypovolemic shocked patients (60 patients) were divided into two main groups according to IVC diameter after the first hour of resuscitation; IVC repleted were 32 patients (53.3%) while 28 patients (46.7%) were IVC non-repleted. In our study population, there were statistically significant differences between repleted and non-repleted IVC cases regarding IVCD, DIVC min, IVCCI (on arrival) (after 1\u00a0h) (after 24\u00a0h of 1st hour of resuscitation) ( <jats:italic>p-<\/jats:italic>value\u2009&lt;\u20090.05) and DIVC Max (on arrival) (after 1\u00a0h) (<jats:italic>p-<\/jats:italic>value\u2009&lt;\u20090.001). There is no statistically significant difference (<jats:italic>p-<\/jats:italic>value\u2009=\u20090.075) between repleted and non-repleted cases regarding DIVC Max (after 24\u00a0h).In our study, we found that IVCci0 at a cut-off point\u2009&gt;\u200938.5 has a sensitivity of 80.0% and Specificity of 85.71% with AUC 0.971 and a good 95% CI (0.938 \u2013 1.0), which means that IVCci of 38.6% or more can indicate fluid responsiveness. We also found that IVCci 1\u00a0h (after fluid resuscitation) at cut-off point\u2009&gt;\u200928.6 has a sensitivity of 80.0% and Specificity of 75% with AUC 0.886 and good 95% CI (0.803 \u2013 0.968), which means that IVCci of 28.5% or less can indicate fluid unresponsiveness after 1st hour of resuscitation. We found no statistically significant difference between repleted and non-repleted cases regarding fluid requirement and amount of blood transfusion at 1st hour of resuscitation (<jats:italic>p-<\/jats:italic>value\u2009=\u20090.104).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Repeated bedside ultrasonography of IVCD, and IVCci before and after the first hour of resuscitation could be an excellent reliable invasive tool that can be used in estimating the First 24\u00a0h of fluid requirement in Major blunt trauma patients and assessment of fluid status.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12873-024-01033-7","type":"journal-article","created":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T07:02:04Z","timestamp":1721113324000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of the role of repeated inferior vena cava sonography in estimating first 24\u00a0h fluid requirement in resuscitation of major blunt trauma patients in emergency department Suez Canal University Hospital"],"prefix":"10.1186","volume":"24","author":[{"given":"Rasha Mahmoud","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassant Sayed","family":"Moussa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Amin","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aml Ibrahiem Sayed Ahmed","family":"Abo El Sood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gouda Mohamed El","family":"Labban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,16]]},"reference":[{"issue":"6","key":"1033_CR1","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1097\/TA.0b013e31823a05b5","volume":"71","author":"J Szopinski","year":"2011","unstructured":"Szopinski J, Kusza K, Semionow M. 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