{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T20:36:55Z","timestamp":1764103015300,"version":"3.37.3"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","award":["R185-2014-2482"],"award-info":[{"award-number":["R185-2014-2482"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Fam Pract"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1186\/s12875-019-0970-3","type":"journal-article","created":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T13:02:22Z","timestamp":1559394142000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Management of sore throat in Danish general practices"],"prefix":"10.1186","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3494-278X","authenticated-orcid":false,"given":"Kasper Basse","family":"Reinholdt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Rusan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pernille Rosbjerg","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tejs Ehlers","family":"Klug","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,6,1]]},"reference":[{"key":"970_CR1","unstructured":"DSAM Luftvejsinfektioner - diagnose og behandling 2014 [Respiratory tract infections - diagnosis and treatment, the Danish Society of General Practitioners, 2014]. \n                    http:\/\/vejledninger.dsam.dk\/luftvejsinfektioner\/\n                    \n                  . Accessed 19 July 2018."},{"issue":"2","key":"970_CR2","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1080\/09674845.2007.11732757","volume":"64","author":"JA Amess","year":"2007","unstructured":"Amess JA, O'Neill W, Giollariabhaigh CN, Dytrych JK. A six-month audit of the isolation of fusobacterium necrophorum from patients with sore throat in a district general hospital. Br J Biomed Sci. 2007;64(2):63\u20135.","journal-title":"Br J Biomed Sci"},{"key":"970_CR3","first-page":"CD000023","volume":"11","author":"A Spinks","year":"2013","unstructured":"Spinks A, Glasziou PP, Del Mar CB. Antibiotics for sore throat. Cochrane Database Syst Rev. 2013;11:CD000023.","journal-title":"Cochrane Database Syst Rev"},{"issue":"13","key":"970_CR4","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1001\/jama.291.13.1587","volume":"291","author":"WJ McIsaac","year":"2004","unstructured":"McIsaac WJ, Kellner JD, Aufricht P, Vanjaka A, Low DE. Empirical validation of guidelines for the management of pharyngitis in children and adults. JAMA. 2004;291(13):1587\u201395.","journal-title":"JAMA."},{"key":"970_CR5","unstructured":"HappyAudit Respiratory tract infections in general practice 2017. \n                    http:\/\/www.apo-danmark.dk\/files\/pub\/5393.pdf\n                    \n                  . Accessed 19 July 2018."},{"issue":"4","key":"970_CR6","doi-asserted-by":"publisher","first-page":"269","DOI":"10.3109\/02813432.2015.1114349","volume":"33","author":"N Run Sigurethardottir","year":"2015","unstructured":"Run Sigurethardottir N, Nielsen AB, Munck A, Bjerrum L. Appropriateness of antibiotic prescribing for upper respiratory tract infections in general practice: comparison between Denmark and Iceland. Scand J Prim Health Care. 2015;33(4):269\u201374.","journal-title":"Scand J Prim Health Care"},{"key":"970_CR7","doi-asserted-by":"publisher","first-page":"1163","DOI":"10.1007\/s10096-014-2052-8","volume":"33","author":"TE Klug","year":"2014","unstructured":"Klug TE. Incidence and microbiology of peritonsillar abscess: the influence of season, age, and gender. Eur J Clin Microbiol Infect Dis. 2014;33:1163\u20137.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"13","key":"970_CR8","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1001\/archinte.166.13.1374","volume":"166","author":"JA Linder","year":"2006","unstructured":"Linder JA, Chan JC, Bates DW. Evaluation and treatment of pharyngitis in primary care practice: the difference between guidelines is largely academic. Arch Intern Med. 2006;166(13):1374\u20139.","journal-title":"Arch Intern Med"},{"issue":"4","key":"970_CR9","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1111\/bcpt.12316","volume":"116","author":"S Malo","year":"2015","unstructured":"Malo S, Bjerrum L, Feja C, Lallana MJ, Moliner J, Rabanaque MJ. Compliance with recommendations on outpatient antibiotic prescribing for respiratory tract infections: the case of Spain. Basic Clin Pharmacol Toxicol. 2015;116(4):337\u201342.","journal-title":"Basic Clin Pharmacol Toxicol"},{"issue":"2","key":"970_CR10","doi-asserted-by":"publisher","first-page":"114","DOI":"10.3109\/13814788.2013.828200","volume":"20","author":"N Adriaenssens","year":"2014","unstructured":"Adriaenssens N, Bartholomeeusen S, Ryckebosch P, Coenen S. Quality of antibiotic prescribtion during office hours and out-of-office hours in Flemish primary care, using European quality indicators. Eur J Gen Pract. 2014;20(2):114\u201320.","journal-title":"Eur J Gen Pract"},{"issue":"6","key":"970_CR11","doi-asserted-by":"publisher","first-page":"1540","DOI":"10.1093\/jac\/dks073","volume":"67","author":"C Pulcini","year":"2012","unstructured":"Pulcini C, Pauvif L, Paraponaris A, Verger P, Ventelou B. Perceptions and attitudes of French general practitioners towards rapid antigen diagnostic tests in acute pharyngitis using a randomized case vignette study. J Antimicrob Chemother. 2012;67(6):1540\u20136.","journal-title":"J Antimicrob Chemother"},{"issue":"11","key":"970_CR12","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1001\/archinternmed.2012.950","volume":"172","author":"AM Fine","year":"2012","unstructured":"Fine AM, Nizet V, Mandl KD. Large-scale validation of the Centor and McIsaac scores to predict group a streptococcal pharyngitis. Arch Intern Med. 2012;172(11):847\u201352.","journal-title":"Arch Intern Med"},{"issue":"3","key":"970_CR13","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1177\/0272989X8100100304","volume":"1","author":"RM Centor","year":"1981","unstructured":"Centor RM, Witherspoon JM, Dalton HP, Brody CE, Link K. The diagnosis of strep throat in adults in the emergency room. Med Decis Mak. 1981;1(3):239\u201346.","journal-title":"Med Decis Mak"},{"key":"970_CR14","unstructured":"PLO: Data from the Organization of General Practitioners in Denmark 2017. \n                    https:\/\/www.laeger.dk\/sites\/default\/files\/plo_faktaark_2017_region_midtjylland_0.pdf\n                    \n                  . Accessed 19 July 2018."},{"key":"970_CR15","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/1471-2466-12-70","volume":"12","author":"AH Palla","year":"2012","unstructured":"Palla AH, Khan RA, Gilani AH, Marra F. Over prescription of antibiotics for adult pharyngitis is prevalent in developing countries but can be reduced using McIsaac modification of Centor scores: a cross-sectional study. BMC Pulm Med. 2012;12:70\u20132466-12-70.","journal-title":"BMC Pulm Med"},{"key":"970_CR16","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/1741-7015-9-67","volume":"9","author":"J Aalbers","year":"2011","unstructured":"Aalbers J, O'Brien KK, Chan WS, Falk GA, Teljeur C, Dimitrov BD, et al. Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score. BMC Med. 2011;9:67\u20137015-9-67.","journal-title":"BMC Med"},{"issue":"12","key":"970_CR17","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1007\/s10096-016-2757-y","volume":"35","author":"TE Klug","year":"2016","unstructured":"Klug TE, Rusan M, Fuursted K, Ovesen T, Jorgensen AW. A systematic review of fusobacterium necrophorum-positive acute tonsillitis: prevalence, methods of detection, patient characteristics, and the usefulness of the Centor score. Eur J Clin Microbiol Infect Dis. 2016;35(12):1903\u201312.","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"970_CR18","unstructured":"Klug TE. Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess. Dan Med J. 2017;64(3):B5333."},{"key":"970_CR19","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12875-015-0285-y","volume":"16","author":"H Grondal","year":"2015","unstructured":"Grondal H, Hedin K, Strandberg EL, Andre M, Brorsson A. Near-patient tests and the clinical gaze in decision-making of Swedish GPs not following current guidelines for sore throat - a qualitative interview study. BMC Fam Pract. 2015;16:81\u2013015-0285-y.","journal-title":"BMC Fam Pract"},{"issue":"1","key":"970_CR20","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/1471-2296-6-6","volume":"6","author":"T Fischer","year":"2005","unstructured":"Fischer T, Fischer S, Kochen MM, Hummers-Pradier E. Influence of patient symptoms and physical findings on general practitioners\u2019 treatment of respiratory tract infections: a direct observation study. BMC Fam Pract. 2005;6(1):6.","journal-title":"BMC Fam Pract"},{"key":"970_CR21","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1186\/1471-2296-13-43","volume":"13","author":"M Murphy","year":"2012","unstructured":"Murphy M, Bradley CP, Byrne S. Antibiotic prescribing in primary care, adherence to guidelines and unnecessary prescribing--an Irish perspective. BMC Fam Pract. 2012;13:43\u20132296-13-43.","journal-title":"BMC Fam Pract"},{"issue":"1","key":"970_CR22","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1038\/s41533-017-0037-7","volume":"27","author":"R Aabenhus","year":"2017","unstructured":"Aabenhus R, Hansen MP, Saust LT, Bjerrum L. Characterisation of antibiotic prescriptions for acute respiratory tract infections in Danish general practice: a retrospective registry based cohort study. NPJ Prim Care Respir Med. 2017;27(1):37.","journal-title":"NPJ Prim Care Respir Med"},{"key":"970_CR23","first-page":"CD010502","volume":"7","author":"JF Cohen","year":"2016","unstructured":"Cohen JF, Bertille N, Cohen R, Chalumeau M. Rapid antigen detection test for group a streptococcus in children with pharyngitis. Cochrane Database Syst Rev. 2016;7:CD010502.","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"970_CR24","doi-asserted-by":"publisher","first-page":"e1623","DOI":"10.1542\/peds.2012-2635","volume":"131","author":"L Ambroggio","year":"2013","unstructured":"Ambroggio L, Thomson J, Murtagh Kurowski E, Courter J, Statile A, Graham C, et al. Quality improvement methods increase appropriate antibiotic prescribing for childhood pneumonia. Pediatrics. 2013;131(5):e1623\u201331.","journal-title":"Pediatrics."},{"issue":"1","key":"970_CR25","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.ijantimicag.2005.03.009","volume":"26","author":"J Segador","year":"2005","unstructured":"Segador J, Gil-Guillen VF, Orozco D, Quirce F, Carratala MC, Fernandez-Parker A, et al. The effect of written information on adherence to antibiotic treatment in acute sore throat. Int J Antimicrob Agents. 2005;26(1):56\u201361.","journal-title":"Int J Antimicrob Agents"},{"issue":"4","key":"970_CR26","doi-asserted-by":"publisher","first-page":"193","DOI":"10.3109\/02813432.2014.972046","volume":"32","author":"K Hedin","year":"2014","unstructured":"Hedin K, Strandberg EL, Grondal H, Brorsson A, Thulesius H, Andre M. Management of patients with sore throats in relation to guidelines: an interview study in Sweden. Scand J Prim Health Care. 2014;32(4):193\u20139.","journal-title":"Scand J Prim Health Care"},{"issue":"1005","key":"970_CR27","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1136\/pgmj.2008.076059","volume":"85","author":"NJ Clifton","year":"2009","unstructured":"Clifton NJ, Raghavan U, Birkin J, Jones NS. Prescribing antibiotics for sore throat: adherence to guidelines in patients admitted to hospital. Postgrad Med J. 2009;85(1005):347\u201351.","journal-title":"Postgrad Med J"},{"issue":"7381","key":"970_CR28","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1136\/bmj.326.7381.138","volume":"326","author":"S Kumar","year":"2003","unstructured":"Kumar S, Little P, Britten N. Why do general practitioners prescribe antibiotics for sore throat? Grounded theory interview study. BMJ. 2003;326(7381):138.","journal-title":"BMJ."},{"issue":"8","key":"970_CR29","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1080\/00365540210147624","volume":"34","author":"I Odenholt","year":"2002","unstructured":"Odenholt I, Bylander-Groth A, Frimodt-Moller N, Rokstad KS, Molstad S. Differences in antibiotic prescribing patterns between general practitioners in Scandinavia: a questionnaire study. Scand J Infect Dis. 2002;34(8):602\u20139.","journal-title":"Scand J Infect Dis"}],"container-title":["BMC Family Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12875-019-0970-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1186\/s12875-019-0970-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1186\/s12875-019-0970-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,30]],"date-time":"2020-05-30T23:07:03Z","timestamp":1590880023000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcfampract.biomedcentral.com\/articles\/10.1186\/s12875-019-0970-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["970"],"URL":"https:\/\/doi.org\/10.1186\/s12875-019-0970-3","relation":{},"ISSN":["1471-2296"],"issn-type":[{"type":"electronic","value":"1471-2296"}],"subject":[],"published":{"date-parts":[[2019,6,1]]},"assertion":[{"value":"20 July 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 May 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 June 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by the Danish Data Protection Agency (2015-57-0002) and data were handled confidentially in strict accordance with the guidelines. According to the Consolidation Act on Research Ethics Review of Health Research Projects, Consolidation Act number 1083 of 15 September 2017, section 14(2) notification of questionnaire surveys or medical database research projects to the research ethics committee system is only required if the project involves human biological material.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"75"}}