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The study protocol was approved by the Conjoint Health Research Ethics Board at the University of Calgary (Calgary, Alberta Canada).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Consent for publication was obtained from all patients in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"MJF has been a consultant to Inova Diagnostics (San Diego, CA), Werfen International (Barcelona, Spain) and BioRad (Hercules, CA, USA). He has also received gifts in kind from Euoimmun GmbH (Luebeck, Germany).MGS has served as a speaker and\/or advisory board member and\/or has received research support from Allergan, Genfit, Bristol Myers Squibb, Gilead Sciences, CymaBay Therapeutics, Abbott, Intercept Pharmaceuticals, Genkyotex, Novartis, Glaxo Smith Kline, Abbvie and Merck. 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