{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T10:42:30Z","timestamp":1780742550203,"version":"3.54.1"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:00:00Z","timestamp":1646265600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:00:00Z","timestamp":1646265600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"1\u00b73\u00b75 project for disciplines of excellence\u2013Clinical Research Incubation Project, West China Hospital, Sichuan University","award":["2019HXFH055"],"award-info":[{"award-number":["2019HXFH055"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Gastroenterol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Portal hypertensive biliopathy (PHB) was caused by anatomical and functional abnormalities in the intrahepatic and extrahepatic bile ducts secondary to portal hypertension. Currently, there is no consensus regarding to the optimal treatment for PHB. Transjugular intrahepatic portosystemic shunt (TIPS) is the treatment choice for the management of symptomatic PHB, however, it could be very difficult in patients with PHB and cavernous transformation of portal vein.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Case presentation<\/jats:title>\n                <jats:p>We report a case of PHB, successfully managed with TIPS. A 23-year-old man with liver cirrhosis presented with jaundice. Magnetic resonance cholangiopancreatography (MRCP) showed multiple tortuous hepatopetal collateral vessels compressing the common bile duct (CBD) and leading to the dilated proximal bile duct. He was diagnosed with PHB and treated with TIPS. A guidewire was inserted into the appropriate collateral vessel through transsplenic approach to guide intrahepatic puncture and TIPS was performed successfully. After the operation, portal vein pressure decreased and the symptoms of biliary obstruction were relieved significantly. In addition, the patient showed no jaundice at a follow-up of one year.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>For PHB patients presenting for cavernous transformation of the portal vein, which precludes the technical feasibility of TIPS, a combined transjugular\/transsplenic approach could be an alternative option.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12876-022-02168-2","type":"journal-article","created":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T14:04:43Z","timestamp":1646316283000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Transjugular intrahepatic portosystemic shunt for the treatment of portal hypertensive biliopathy with cavernous transformation of the portal vein: a case report"],"prefix":"10.1186","volume":"22","author":[{"given":"Ming","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoze","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bangxi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3992-5866","authenticated-orcid":false,"given":"Xuefeng","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,3]]},"reference":[{"key":"2168_CR1","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1136\/gut.33.2.272","volume":"33","author":"JB Dilawari","year":"1992","unstructured":"Dilawari JB, Chawla YK. Pseudosclerosing cholangitis in extrahepatic portal venous obstruction. Gut. 1992;33:272\u20136.","journal-title":"Gut"},{"key":"2168_CR2","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1002\/hep.1840170510","volume":"17","author":"MS Khuroo","year":"1993","unstructured":"Khuroo MS, Yattoo GN, Zargar SA, et al. Biliary abnormalities associated with extrahepatic portal venous obstruction. Hepatology. 1993;17:807\u201313.","journal-title":"Hepatology"},{"key":"2168_CR3","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1053\/jhep.2003.50232","volume":"37","author":"B Condat","year":"2003","unstructured":"Condat B, Vilgrain V, Asselah T, et al. Portal cavernoma-associated cholangiopathy: a clinical and MR cholangiography coupled with MR portography imaging study. 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Disappearance of \u201cpseudocholangiocarcinoma sign\u201d in a patient with portal hypertension due to complete thrombosis of left portal vein and main portal vein web after web dilatation and transjugular intrahepatic portosystemic shunt. J Clin Gastroenterol. 2000;31:328\u201332.","journal-title":"J Clin Gastroenterol"},{"key":"2168_CR9","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1097\/MEG.0b013e3283060ee8","volume":"21","author":"YH Oo","year":"2009","unstructured":"Oo YH, Olliff S, Haydon G, et al. Symptomatic portal biliopathy: a single centre experience from the UK. Eur J Gastroenterol Hepatol. 2009;21:206\u201313.","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"2168_CR10","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1111\/ans.12436","volume":"85","author":"PP Cellich","year":"2015","unstructured":"Cellich PP, Crawford M, Kaffes AJ, et al. Portal biliopathy: multidisciplinary management and outcomes of treatment. ANZ J Surg. 2015;85:561\u20136.","journal-title":"ANZ J Surg"},{"key":"2168_CR11","unstructured":"Gorgul A, Kayhan B, Dogan I, et al. Disappearance of the pseudocholangiocarcinoma sign after TIPSS. Am. J. Gastroenterol 1996; 150\u2013154"},{"key":"2168_CR12","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/j.jvir.2014.12.012","volume":"26","author":"A Habib","year":"2015","unstructured":"Habib A, Desai K, Hickey R, et al. Portal vein recanalization-transjugularintrahepatic portosystemic shunt using the transsplenic approach to achieve transplant candidacy in patients with chronic portal vein thrombosis. J Vasc Interv Radiol. 2015;26:499\u2013506.","journal-title":"J Vasc Interv Radiol"},{"key":"2168_CR13","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1136\/gut.2006.103606","volume":"56","author":"RK Dhiman","year":"2007","unstructured":"Dhiman RK, Behera A, Chawla YK, et al. Portal hypertensive biliopathy. 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This study was approved by the Ethics Committee of the West China Hospital (Chengdu, China).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Consent for publication was obtained from the patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"96"}}