{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:24:19Z","timestamp":1792290259504,"version":"4.4.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T00:00:00Z","timestamp":1652832000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T00:00:00Z","timestamp":1652832000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Gastroenterol"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Achalasia is a rare primary esophageal motility disorder disease. It is reported that the long-term effect of fully coated anti-reflux metal stent (FCARMS) implantation is satisfactory. Operated by a skilled and experienced endoscopist, the effect of per-oral endoscopic myotomy (POEM) treatment is equivalent to that of surgical myotomy. So far, there is still few evidence to prove FCARMS implantation or POEM which is better for achalasia. The choice of treatment for achalasia is still controversial. The aim of this study is to find a more suitable therapy for achalasia by comparing the efficacy of FCARMS implantation and POEM.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A propensity score (PS) matching (1:2) was used in this retrospective cohort study. Data collected from consecutive patients of Achalasia, receiving FCARMS implantation or POEM therapy at the department of gastroenterology, the Seventh Medical Center of the Chinese People\u2019s Liberation Army General Hospital from May 2007 to May 2018. According to their previous treatment, they are divided into two groups, FCARMS group and POEM group. Clinical efficacy and complications were compared between the two groups.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 166 cases were collected, including 113 cases of FCARMS and 53 cases of POEM. By PS matching, 150 patients were enrolled (100 cases of FCARMS and 50 cases of POEM). By comparison, the FCARMS group has shorter operation time, shorter fasting time and lower hospitalization costs than the POEM group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Common complications in the FCARMS group are nausea, vomiting, and stent shift. Repetitions of gastroscopy in the FCARMS group was more often, which were 3.8\u2009\u00b1\u20092.4 (vs 2.1\u2009\u00b1\u20091.8 of POEM) (<jats:italic>p<\/jats:italic>\u2009=\u20090.00\u2009&lt;\u20090.05) The 6-month remission rates of the FCARMS combination POEM group were 89% and 94%, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.39), and the 2-year remission rates were 61% and 90%, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.00).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Stent placement is a cost-effective and safe treatment option for achalasia. The short-term effect (less than 6\u00a0months) of FCARMS is similar to that of POEM, the long-term effect (more than 2\u00a0years), POEM is better than FCARMS. HRMIIis most suitable for POEM treatment. It indicate that Patients can choose treatment methods according to their own conditions.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12876-022-02282-1","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T18:02:51Z","timestamp":1652896971000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of fully coated anti-reflux metal stenting and per-oral endoscopic myotomy in patients with achalasia: a propensity score-matched retrospective study"],"prefix":"10.1186","volume":"22","author":[{"given":"Yu-fen","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-rong","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongliang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-qiu","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,5,18]]},"reference":[{"issue":"Suppl 12","key":"2282_CR1","doi-asserted-by":"publisher","first-page":"S1618-S1628","DOI":"10.21037\/jtd.2019.07.84","volume":"11","author":"Y Ahmed","year":"2019","unstructured":"Ahmed Y, Othman MO. Peroral endoscopic myotomy (POEM) for achalasia. J Thorac Dis. 2019;11(Suppl 12):S1618S1628. https:\/\/doi.org\/10.21037\/jtd.2019.07.84 (PMID:31489229;PMCID:PMC670239).","journal-title":"J Thorac Dis"},{"issue":"9911","key":"2282_CR2","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/S0140-6736(13)60651-0","volume":"383","author":"GE Boeckxstaens","year":"2014","unstructured":"Boeckxstaens GE, Zaninotto G, Richter JE. Achalasia. Lancet. 2014;383(9911):83\u201393. https:\/\/doi.org\/10.1016\/S0140-6736(13)60651-0 (Epub 2013 Jul 17 PMID: 23871090).","journal-title":"Lancet"},{"issue":"3","key":"2282_CR3","first-page":"301","volume":"28","author":"F Torresan","year":"2015","unstructured":"Torresan F, Ioannou A, Azzaroli F, Bazzoli F. Treatment of achalasia in the era of high-resolution manometry. Ann Gastroenterol. 2015;28(3):301\u20138 (PMID: 26130022; PMCID: PMC4480166).","journal-title":"Ann Gastroenterol"},{"issue":"5","key":"2282_CR4","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1016\/j.suc.2011.06.005","volume":"91","author":"WC Beck","year":"2011","unstructured":"Beck WC, Sharp KW. Achalasia. Surg Clin N Am. 2011;91(5):1031\u20137. https:\/\/doi.org\/10.1016\/j.suc.2011.06.005 (PMID: 21889028).","journal-title":"Surg Clin N Am"},{"issue":"9","key":"2282_CR5","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1007\/s11605-013-2252-z","volume":"17","author":"ME Allaix","year":"2013","unstructured":"Allaix ME, Patti MG. What is the best primary therapy for achalasia: medical or surgical treatment? Who owns achalasia? J Gastrointest Surg. 2013;17(9):1547\u20139. https:\/\/doi.org\/10.1007\/s11605-013-2252-z (Epub 2013 Jun 19 PMID: 23780637).","journal-title":"J Gastrointest Surg"},{"issue":"3","key":"2282_CR6","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1097\/SLA.0000000000002311","volume":"267","author":"F Schlottmann","year":"2018","unstructured":"Schlottmann F, Luckett DJ, Fine J, Shaheen NJ, Patti MG. Laparoscopic heller myotomy versus peroral endoscopic myotomy (POEM) for achalasia: a systematic review and meta-analysis. Ann Surg. 2018;267(3):451\u201360. https:\/\/doi.org\/10.1097\/SLA.0000000000002311 (PMID: 28549006).","journal-title":"Ann Surg"},{"issue":"33","key":"2282_CR7","doi-asserted-by":"publisher","first-page":"5421","DOI":"10.3748\/wjg.v19.i33.5421","volume":"19","author":"SK Chuah","year":"2013","unstructured":"Chuah SK, Chiu CH, Tai WC, Lee JH, Lu HI, Changchien CS, Tseng PH, Wu KL. Current status in the treatment options for esophageal achalasia. World J Gastroenterol. 2013;19(33):5421\u20139. https:\/\/doi.org\/10.3748\/wjg.v19.i33.5421 (PMID: 24023484; PMCID: PMC3761094).","journal-title":"World J Gastroenterol"},{"issue":"3","key":"2282_CR8","doi-asserted-by":"publisher","first-page":"4117","DOI":"10.1038\/ajg.2011.388","volume":"107","author":"D von Renteln","year":"2012","unstructured":"von Renteln D, Inoue H, Minami H, Werner YB, Pace A, Kersten JF, Much CC, Schachschal G, Mann O, Keller J, Fuchs KH, R\u00f6sch T. Peroral endoscopic myotomy for the treatment of achalasia: a prospective single center study. Am J Gastroenterol. 2012;107(3):4117. https:\/\/doi.org\/10.1038\/ajg.2011.388 (Epub 2011 Nov 8.PMID: 22068665).","journal-title":"Am J Gastroenterol"},{"issue":"3","key":"2282_CR9","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1586\/17474124.2.3.435","volume":"2","author":"JE Richter","year":"2008","unstructured":"Richter JE. Update on the management of achalasia: balloons, surgery and drugs. Expert Rev Gastroenterol Hepatol. 2008;2(3):435\u201345. https:\/\/doi.org\/10.1586\/17474124.2.3.435 (PMID: 19072391).","journal-title":"Expert Rev Gastroenterol Hepatol"},{"issue":"6","key":"2282_CR10","doi-asserted-by":"publisher","first-page":"738","DOI":"10.3904\/kjim.2014.29.6.738","volume":"29","author":"HE Jung","year":"2014","unstructured":"Jung HE, Lee JS, Lee TH, Kim JN, Hong SJ, Kim JO, Kim HG, Jeon SR, Cho JY. Long-term outcomes of balloon dilation versus botulinum toxin injection in patients with primary achalasia. Korean J Intern Med. 2014;29(6):738\u201345. https:\/\/doi.org\/10.3904\/kjim.2014.29.6.738 (Epub 2014 Oct 31. PMID: 25378972; PMCID: PMC4219963).","journal-title":"Korean J Intern Med"},{"issue":"12","key":"2282_CR11","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1038\/ajg.2012.332","volume":"107","author":"KL Lynch","year":"2012","unstructured":"Lynch KL, Pandolfino JE, Howden CW, Kahrilas PJ. Major complications of pneumatic dilation and Heller myotomy for achalasia: single-center experience and systematic review of the literature. Am J Gastroenterol. 2012;107(12):1817\u201325. https:\/\/doi.org\/10.1038\/ajg.2012.332 (Epub 2012 Oct 2. PMID: 23032978; PMCID: PMC3808165).","journal-title":"Am J Gastroenterol"},{"issue":"8","key":"2282_CR12","doi-asserted-by":"publisher","first-page":"1973","DOI":"10.1007\/s00330-009-1373-y","volume":"19","author":"JG Zhao","year":"2009","unstructured":"Zhao JG, Li YD, Cheng YS, Li MH, Chen NW, Chen WX, Shang KZ. Long-term safety and outcome of a temporary self-expanding metallic stent for achalasia: a prospective study with a 13-year single-center experience. Eur Radiol. 2009;19(8):1973\u201380. https:\/\/doi.org\/10.1007\/s00330-009-1373-y (Epub 2009 Mar 19. PMID: 19296113; PMCID: PMC2705705).","journal-title":"Eur Radiol"},{"issue":"2","key":"2282_CR13","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1111\/dote.12083","volume":"27","author":"Y Zeng","year":"2014","unstructured":"Zeng Y, Dai YM, Wan XJ. Clinical remission following endoscopic placement of retrievable, fully covered metal stents in patients with esophageal achalasia. Dis Esophagus. 2014;27(2):103\u20138. https:\/\/doi.org\/10.1111\/dote.12083 (Epub 2013 Jun 24. PMID: 2379612).","journal-title":"Dis Esophagus"},{"key":"2282_CR14","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000001622","author":"A Facciorusso","year":"2021","unstructured":"Facciorusso A, Ramai D, Ichkhanian Y, Yadlapati R, Annese V, Wani S, Khashab MA. Peroral endoscopic myotomy for the treatment of esophageal diverticula: a systematic review and meta-analysis. J Clin Gastroenterol. 2021. https:\/\/doi.org\/10.1097\/MCG.0000000000001622 (Epub ahead of print. PMID: 34608024).","journal-title":"J Clin Gastroenterol"},{"issue":"6","key":"2282_CR15","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1111\/1751-2980.12241","volume":"16","author":"H Zhao","year":"2015","unstructured":"Zhao H, Wan XJ, Yang CQ. Comparison of endoscopic balloon dilation with metal stent placement in the treatment of achalasia. J Dig Dis. 2015;16(6):311\u20138. https:\/\/doi.org\/10.1111\/1751-2980.12241 (PMID: 25765898).","journal-title":"J Dig Dis"},{"key":"2282_CR16","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1055\/s-0029-1244080","volume":"42","author":"H Inoue","year":"2010","unstructured":"Inoue H, Minami H, Kobayashi Y, et al. Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy. 2010;42:265\u201371. https:\/\/doi.org\/10.1055\/s-0029-1244080.","journal-title":"Endoscopy"},{"issue":"2","key":"2282_CR17","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/S1052-5157(18)30071-0","volume":"11","author":"VF Eckardt","year":"2001","unstructured":"Eckardt VF. Clinical presentations and complications of achalasia. Gastrointest Endosc Clin N Am. 2001;11(2):281\u201392 (PMID: 11319062).","journal-title":"Gastrointest Endosc Clin N Am"},{"issue":"12","key":"2282_CR18","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1016\/j.kjms.2015.10.003","volume":"31","author":"HM Wang","year":"2015","unstructured":"Wang HM, Tai WC, Chuah SK, Lu HI, Lu LS, Liang CM, Kuo CH, Chiu YC, Wu KL, Changchien CS. Comparison of treatment outcomes of endoscope-guided pneumatic dilation and laparoscopic Heller myotomy. Kaohsiung J Med Sci. 2015;31(12):639\u201343. https:\/\/doi.org\/10.1016\/j.kjms.2015.10.003 (Epub 2015 Nov 30 PMID: 26709226).","journal-title":"Kaohsiung J Med Sci"},{"issue":"6-7","key":"2282_CR19","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1177\/2040622317710010","volume":"8","author":"Z Arora","year":"2017","unstructured":"Arora Z, Thota PN, Sanaka MR. Achalasia: current therapeutic options. Ther Adv Chronic Dis. 2017;8(6\u20137):101\u20138. https:\/\/doi.org\/10.1177\/2040622317710010 (Epub 2017 Jun 23. PMID: 28717439; PMCID: PMC5502956).","journal-title":"Ther Adv Chronic Dis"},{"issue":"5","key":"2282_CR20","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1053\/j.gastro.2008.07.022","volume":"135","author":"JE Pandolfino","year":"2008","unstructured":"Pandolfino JE, Kwiatek MA, Nealis T, Bulsiewicz W, Post J, Kahrilas PJ. Achalasia: a new clinically relevant classification by high-resolution manometry. Gastroenterology. 2008;135(5):1526\u201333.","journal-title":"Gastroenterology"},{"issue":"2","key":"2282_CR21","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1111\/nmo.12477","volume":"27","author":"PJ Kahrilas","year":"2015","unstructured":"Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJ, Pandolfino JE, International High Resolution Manometry Working Group. The Chicago classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil. 2015;27(2):160\u201374. https:\/\/doi.org\/10.1111\/nmo.12477 (Epub 2014 Dec 3. PMID: 25469569; PMCID: PMC4308501).","journal-title":"Neurogastroenterol Motil"},{"issue":"4","key":"2282_CR22","doi-asserted-by":"publisher","first-page":"556","DOI":"10.3748\/wjg.v19.i4.556","volume":"19","author":"HK Li","year":"2013","unstructured":"Li HK, Linghu EQ. New endoscopic classification of achalasia for selection of candidates for peroral endoscopic myotomy. World J Gastroenterol. 2013;19(4):556\u201360. https:\/\/doi.org\/10.3748\/wjg.v19.i4.556 (PMID: 23382636; PMCID: PMC3558581).","journal-title":"World J Gastroenterol"},{"issue":"8","key":"2282_CR23","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.cgh.2013.01.032","volume":"11","author":"JE Pandolfino","year":"2013","unstructured":"Pandolfino JE, Kahrilas PJ. Presentation, diagnosis, and management of achalasia. Clin Gastroenterol Hepatol. 2013;11(8):887\u201397. https:\/\/doi.org\/10.1016\/j.cgh.2013.01.032 (Epub 2013 Feb 8 PMID: 23395699).","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"2","key":"2282_CR24","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1007\/s00464-005-0365-5","volume":"20","author":"N Omura","year":"2006","unstructured":"Omura N, Kashiwagi H, Ishibashi Y, Yano F, Tsuboi K, Kawasaki N, Suzuki Y, Yanaga K. Laparoscopic Heller myotomy and Dor fundoplication for the treatment of achalasia. Assessment in relation to morphologic type. Surg Endosc. 2006;20(2):210\u20133. https:\/\/doi.org\/10.1007\/s00464-005-0365-5 (Epub 2005 Nov 21. PMID: 16328672).","journal-title":"Surg Endosc"},{"issue":"35\u201336","key":"2282_CR25","doi-asserted-by":"publisher","first-page":"597","DOI":"10.3238\/arztebl.2016.0597","volume":"113","author":"O Kuss","year":"2016","unstructured":"Kuss O, Blettner M, B\u00f6rgermann J. Propensity score: an alternative method of analyzing treatment effects. Dtsch Arztebl Int. 2016;113(35\u201336):597\u2013603. https:\/\/doi.org\/10.3238\/arztebl.2016.0597 (PMID: 27658473; PMCID: PMC5963493).","journal-title":"Dtsch Arztebl Int"},{"key":"2282_CR26","doi-asserted-by":"publisher","first-page":"S95","DOI":"10.1055\/s-2007-1001412","volume":"30","author":"GD De Palma","year":"1998","unstructured":"De Palma GD, Catanzano C. Removable self-expanding metal stents: a pilot study for treatment of achalasia of the esophagus. Endoscopy. 1998;30:S95\u20136.","journal-title":"Endoscopy"},{"issue":"1","key":"2282_CR27","doi-asserted-by":"publisher","first-page":"45","DOI":"10.4253\/wjge.v7.i1.45","volume":"7","author":"AD Sioulas","year":"2015","unstructured":"Sioulas AD, Malli C, Dimitriadis GD, Triantafyllou K. Self-expandable metal stents for achalasia: thinking out of the box! World J Gastrointest Endosc. 2015;7(1):45\u201352. https:\/\/doi.org\/10.4253\/wjge.v7.i1.45 (PMID: 25610533; PMCID: PMC4295180).","journal-title":"World J Gastrointest Endosc"},{"issue":"8","key":"2282_CR28","doi-asserted-by":"publisher","first-page":"4305","DOI":"10.1007\/s00464-020-07920-x","volume":"35","author":"A Facciorusso","year":"2021","unstructured":"Facciorusso A, Singh S, Abbas Fehmi SM, Annese V, Lipham J, Yadlapati R. Comparative efficacy of first-line therapeutic interventions for achalasia: a systematic review and network meta-analysis. Surg Endosc. 2021;35(8):4305\u201314. https:\/\/doi.org\/10.1007\/s00464-020-07920-x (PMID: 32856150; PMCID: PMC8011535).","journal-title":"Surg Endosc"},{"issue":"7","key":"2282_CR29","doi-asserted-by":"publisher","first-page":"E1097","DOI":"10.1055\/a-1483-9406","volume":"9","author":"A Ofosu","year":"2021","unstructured":"Ofosu A, Mohan BP, Ichkhanian Y, Masadeh M, Febin J, Barakat M, Ramai D, Chandan S, Haiyeva G, Khan SR, Aghaie Meybodi M, Facciorusso A, Repici A, Wani S, Thosani N, Khashab MA. Peroral endoscopic myotomy (POEM) vs pneumatic dilation (PD) in treatment of achalasia: A meta-analysis of studies with \u2265 12-month follow-up. Endosc Int Open. 2021;9(7):E1097\u2013107. https:\/\/doi.org\/10.1055\/a-1483-9406 (PMID: 34222636; PMCID: PMC8216779).","journal-title":"Endosc Int Open"},{"issue":"8","key":"2282_CR30","doi-asserted-by":"publisher","first-page":"E1246","DOI":"10.1055\/a-1490-8493","volume":"9","author":"S Chandan","year":"2021","unstructured":"Chandan S, Facciorusso A, Khan SR, Ramai D, Mohan BP, Bilal M, Dhindsa B, Kassab LL, Goyal H, Perisetti A, Bhat I, Singh S, McDonough S, Adler DG. Short versus standard esophageal myotomy in achalasia patients: a systematic review and meta-analysis of comparative studies. Endosc Int Open. 2021;9(8):E1246\u201354. https:\/\/doi.org\/10.1055\/a-1490-8493 (Epub 2021 Jul 16. PMID: 34447872; PMCID: PMC8383091).","journal-title":"Endosc Int Open"},{"issue":"11","key":"2282_CR31","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.1007\/s11605-010-1318-4","volume":"14","author":"R Salvador","year":"2010","unstructured":"Salvador R, Costantini M, Zaninotto G, Morbin T, Rizzetto C, Zanatta L, Ceolin M, Finotti E, Nicoletti L, Da Dalt G, Cavallin F, Ancona E. The preoperative manometric pattern predicts the outcome of surgical treatment for esophageal achalasia. J Gastrointest Surg. 2010;14(11):1635\u201345. https:\/\/doi.org\/10.1007\/s11605-010-1318-4 (Epub 2010 Sep 10 PMID: 20830530).","journal-title":"J Gastrointest Surg"},{"issue":"5","key":"2282_CR32","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1097\/MOG.0000000000000206","volume":"31","author":"SN Stavropoulos","year":"2015","unstructured":"Stavropoulos SN, Modayil R, Friedel D. Per oral endoscopic myotomy for the treatment of achalasia. Curr Opin Gastroenterol. 2015;31(5):430\u201340. https:\/\/doi.org\/10.1097\/MOG.0000000000000206 (PMID: 26200001).","journal-title":"Curr Opin Gastroenterol"}],"container-title":["BMC Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12876-022-02282-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12876-022-02282-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12876-022-02282-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T18:06:26Z","timestamp":1652897186000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/10.1186\/s12876-022-02282-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,18]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["2282"],"URL":"https:\/\/doi.org\/10.1186\/s12876-022-02282-1","relation":{},"ISSN":["1471-230X"],"issn-type":[{"value":"1471-230X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,18]]},"assertion":[{"value":"29 July 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All methods in this study were carried out in accordance with relevant guidelines and regulations. This study protocol was approved by the Ethics Research Committee of the seventh medical center of the People\u2019s Liberation Army General Hospital. All patients provided written, informed consent to participate in the study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors declare no conflict of interest in this study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"253"}}