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The main pancreatic duct (MPD) was evaluated in the head of the pancreas by its course, which were non-MMPD: descending, vertical, and sigmoid, or MMPD including loop types, reverse-Z subtypes, and an N-shape, which was identified for the first time in this study. IPMN patients were also evaluated for worrisome features (WF) or high-risk stigmata (HRS), and the extent of IPMN cysts.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among IPMN patients, 18.4% had MMPD, which we observed in only 3.0% of the control group (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Patients with MMPD were more likely to belong to the IPMN group compared with non-MMPD patients [odds ratio (OR) 6.4, 95% confidence interval (CI) 2.2\u201324.9]. Compared with a descending shape MPD, IPMN patients with an N-shaped MPD were more likely to have a cystic mural nodule (OR 5.9, 95% CI 1.02\u201336.0). The presence of ansa pancreatica associated with more extent IPMN disease (OR 12.8, 95% CI 2.6\u2013127.7).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>IPMN patients exhibited an MMPD more often than control patients. Ansa pancreatica associated with multiple cysts. Furthermore, an N-shape in IPMN patients associated with cystic mural nodules, suggesting that this shape serves as a risk factor for more severe IPMN.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1186\/s12876-022-02465-w","type":"journal-article","created":{"date-parts":[[2022,8,21]],"date-time":"2022-08-21T14:02:38Z","timestamp":1661090558000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Anatomical pancreatic variants in intraductal papillary mucinous neoplasm patients: a cross-sectional study"],"prefix":"10.1186","volume":"22","author":[{"given":"Katarina","family":"Johansson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harri","family":"Mustonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Sepp\u00e4nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiina E.","family":"Lehtim\u00e4ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,8,21]]},"reference":[{"issue":"5","key":"2465_CR1","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1136\/gutjnl-2018-316027","volume":"67","author":"European Study Group on Cystic Tumours of the Pancreas","year":"2018","unstructured":"European Study Group on Cystic Tumours of the Pancreas. 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All methods were carried out in accordance with the Declaration of Helsinki. We were not obligated to secure written informed consent from patients because of the retrospective nature of this study and based on the Act on the Secondary Use of Health and Social data (552\/2019).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Because of the retrospective nature of this study and the Act on the Secondary Use of Health and Social data (552\/2019), the written informed consent of the patients was not demanded and it was waived by IRB approval.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare that they have no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"394"}}