{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T10:52:22Z","timestamp":1740135142260,"version":"3.37.3"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T00:00:00Z","timestamp":1691193600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T00:00:00Z","timestamp":1691193600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["BMC Gastroenterol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We read with interest the study by Freitas et al. comparing contrast-enhanced ultrasound (CEUS) and parameters from a time-intensity curve (TIC) with the SUS-CD score and IBUS-SAS score in patients with Crohn\u2019s disease (CD) undergoing gastrointestinal ultrasound (GIUS) and ileocolonoscopy. The aim was to compare the accuracy of CEUS and aforementioned scores in predicting terminal ileal inflammatory activity in patients with CD. In this retrospective study of 50 patients, inflammatory activity was defined as a segmental score of SES-CD\u2009\u2265\u20097 in the terminal ileum. The study found 30 patients with active endoscopic disease demonstrating no significant difference between the \u201cinactive\u201d and \u201cactive\u201d SUS CD and IBUS-SAS scores. However, the CEUS peak enhancement derived from the TIC was shown to be significantly different. The authors conclude CEUS was superior for detecting inflammation in the terminal ileum, as opposed to ultrasound scores relying on bowel wall thickness and color Doppler.<\/jats:p>","DOI":"10.1186\/s12876-023-02882-5","type":"journal-article","created":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T23:01:47Z","timestamp":1691190107000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comment on \u201cUltrasonographic scores for ileal Crohn\u2019s disease assessment: better, worse or the same as contrast\u2011enhanced ultrasound?\u201d"],"prefix":"10.1186","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8178-3614","authenticated-orcid":false,"given":"Kim","family":"Nylund","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerri","family":"Novak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4928-4708","authenticated-orcid":false,"given":"Rune","family":"Wilkens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,8,5]]},"reference":[{"issue":"1","key":"2882_CR1","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1186\/s12876-022-02326-6","volume":"22","author":"M Freitas","year":"2022","unstructured":"Freitas M, de Castro FD, Macedo Silva V, Arieira C, Curdia Goncalves T, Leite S, et al. Ultrasonographic scores for ileal Crohn\u2019s disease assessment: better, worse or the same as contrast-enhanced ultrasound? BMC Gastroenterol. 2022;22(1):252.","journal-title":"BMC Gastroenterol"},{"issue":"1","key":"2882_CR2","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1093\/ecco-jcc\/jjaa112","volume":"15","author":"F Saevik","year":"2021","unstructured":"Saevik F, Eriksen R, Eide GE, Gilja OH, Nylund K. Development and validation of a simple ultrasound activity score for Crohn\u2019s Disease. J Crohns Colitis. 2021;15(1):115\u201324.","journal-title":"J Crohns Colitis"},{"issue":"4","key":"2882_CR3","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1093\/ecco-jcc\/jjaa216","volume":"15","author":"KL Novak","year":"2021","unstructured":"Novak KL, Nylund K, Maaser C, Petersen F, Kucharzik T, Lu C, et al. Expert Consensus on Optimal Acquisition and Development of the International Bowel Ultrasound Segmental Activity score [IBUS-SAS]: a reliability and inter-rater variability study on intestinal Ultrasonography in Crohn\u2019s Disease. J Crohns Colitis. 2021;15(4):609\u201316.","journal-title":"J Crohns Colitis"},{"issue":"3","key":"2882_CR4","doi-asserted-by":"publisher","first-page":"183","DOI":"10.4103\/1319-3767.182455","volume":"22","author":"E Koutroumpakis","year":"2016","unstructured":"Koutroumpakis E, Katsanos KH. Implementation of the simple endoscopic activity score in crohn\u2019s disease. Saudi J Gastroenterol. 2016;22(3):183\u201391.","journal-title":"Saudi J Gastroenterol"},{"issue":"5","key":"2882_CR5","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1053\/j.gastro.2020.12.031","volume":"160","author":"D Turner","year":"2021","unstructured":"Turner D, Ricciuto A, Lewis A, D\u2019Amico F, Dhaliwal J, Griffiths AM, et al. STRIDE-II: an update on the selecting therapeutic targets in inflammatory bowel Disease (STRIDE) Initiative of the International Organization for the study of IBD (IOIBD): determining therapeutic goals for treat-to-target strategies in IBD. Gastroenterology. 2021;160(5):1570\u201383.","journal-title":"Gastroenterology"},{"issue":"3","key":"2882_CR6","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1093\/ecco-jcc\/jjv196","volume":"10","author":"Z Serafin","year":"2016","unstructured":"Serafin Z, Bialecki M, Bialecka A, Sconfienza LM, Klopocka M. Contrast-enhanced Ultrasound for detection of Crohn\u2019s Disease activity: systematic review and Meta-analysis. J Crohns Colitis. 2016;10(3):354\u201362.","journal-title":"J Crohns Colitis"},{"issue":"11","key":"2882_CR7","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1016\/j.ultrasmedbio.2018.06.018","volume":"44","author":"R Wilkens","year":"2018","unstructured":"Wilkens R, Wilson A, Burns PN, Ghosh S, Wilson SR. Persistent enhancement on contrast-enhanced Ultrasound studies of severe Crohn\u2019s Disease: Stuck bubbles? Ultrasound Med Biol. 2018;44(11):2189\u201398.","journal-title":"Ultrasound Med Biol"},{"key":"2882_CR8","doi-asserted-by":"crossref","unstructured":"de Voogd F, Bots S, Gecse K, Gilja OH, D\u2019Haens G, Nylund K. Intestinal ultrasound early on in treatment follow-up predicts endoscopic response to anti-TNFalpha treatment in Crohn\u2019s Disease. J Crohns Colitis. 2022.","DOI":"10.1093\/ecco-jcc\/jjac072"},{"issue":"1","key":"2882_CR9","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1093\/ibd\/izaa134","volume":"27","author":"T Ripolles","year":"2021","unstructured":"Ripolles T, Poza J, Suarez Ferrer C, Martinez-Perez MJ, de Martin-Algibez A. Las Heras Paez B. evaluation of Crohn\u2019s Disease activity: development of an Ultrasound score in a Multicenter Study. Inflamm Bowel Dis. 2021;27(1):145\u201354.","journal-title":"Inflamm Bowel Dis"},{"issue":"1","key":"2882_CR10","doi-asserted-by":"publisher","first-page":"E13","DOI":"10.1055\/s-0042-123841","volume":"3","author":"R Wilkens","year":"2017","unstructured":"Wilkens R, Peters DA, Nielsen AH, Hovgaard VP, Glerup H, Krogh K. Dynamic contrast-enhanced magnetic resonance enterography and dynamic contrast-enhanced Ultrasonography in Crohn\u2019s Disease: an observational comparison study. Ultrasound Int Open. 2017;3(1):E13\u2013E24.","journal-title":"Ultrasound Int Open"}],"container-title":["BMC Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12876-023-02882-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1186\/s12876-023-02882-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1186\/s12876-023-02882-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T09:16:30Z","timestamp":1700471790000},"score":1,"resource":{"primary":{"URL":"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/10.1186\/s12876-023-02882-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,5]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,12]]}},"alternative-id":["2882"],"URL":"https:\/\/doi.org\/10.1186\/s12876-023-02882-5","relation":{},"ISSN":["1471-230X"],"issn-type":[{"type":"electronic","value":"1471-230X"}],"subject":[],"published":{"date-parts":[[2023,8,5]]},"assertion":[{"value":"4 January 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 July 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 August 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors have non-financial competing interest as they are co-authors on one or two of the papers under discussion in the manuscript.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"265"}}